In the article entitled “Physiologically Based Pharmacokinetics Model of Primidone and Its Metabolites Phenobarbital and Phenylethylmalonamide in Humans, Rats, and Mice” (El-Masri HA and Portier CJ (1998)26:585–594), Dr. Patrick Poulin noted the following errors in Tables 2 and 3, about which the authors of the article agree. The neutral lipids content of plasma in Table 2 should be 0.639 instead of 0.6311. The neutral lipids content of adipose tissue in Table 2 should be 0.997 instead of 0.11. The neutral lipids content of muscle tissue should be 0.459 instead of 0.4511. The total lipids content of muscle tissue in Table 2 should be 0.019 instead of 0.0111. The neutral lipids content of adipose tissue in Table 3 should be 0.999 instead of 0.1111. The reference concerning the phospholipids content of muscle tissue in Table 3 should be (De Krester et al., 1977) instead of (Poulin and Krishnan, 1995a). The complete reference of this item is as follows: De Krester TA, Livett BG (1977) Skeletal-muscle sarcolemma from normal and dystrophic mice: isolation, characterization, and lipid composition. Biochem J 168:229–237. In all cases, these were simple typographical errors, and the correct values were used in our analysis.

• The American Society for Pharmacology and Experimental Therapeutics