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Drug Metabolism & Disposition

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Table of Contents

March 01, 1998; Volume 26,Issue 3

Accelerated Communication

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    Thiodiglycolic Acid is Excreted by Humans Receiving Ifosfamide and Inhibits Mitochondrial Function in Rats
    Theresa M. Visarius, Heinz Bähler, Adrian Küpfer, Thomas Cerny and Bernhard H. Lauterburg
    Drug Metabolism and Disposition March 1998, 26 (3) 193-196;

Articles

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    Dermal Absorption and Pharmacokinetics of Isopropanol in the Male and Female F-344 Rat
    Rodney J. Boatman, Louise G. Perry, Laurie A. Fiorica, J. Caroline English, Robert W. Kapp, Christopher Bevan, Tipton R. Tyler, Marcy I. Banton and Gary A. Wright
    Drug Metabolism and Disposition March 1998, 26 (3) 197-202;
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    In Vitro Transesterification of Cocaethylene (Ethylcocaine) in the Presence of Ethanol
    James A. Bourland, Debra K. Martin and Michael Mayersohn
    Drug Metabolism and Disposition March 1998, 26 (3) 203-206;
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    Evaluation of the Selectivity of In Vitro Probes and Suitability of Organic Solvents for the Measurement of Human Cytochrome P450 Monooxygenase Activities
    Dean Hickman, Ji-Ping Wang, Yi Wang and Jashvant D. Unadkat
    Drug Metabolism and Disposition March 1998, 26 (3) 207-215;
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    In Vivo Clearance of Ethoxycoumarin and Its Prediction from In Vitro Systems
    David J. Carlile, Alex J. Stevens, Elizabeth I. L. Ashforth, Daxa Waghela and J. Brian Houston
    Drug Metabolism and Disposition March 1998, 26 (3) 216-221;
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    Biotransformation of 13-cis- and 9-cis-Retinoic Acid to All-trans-Retinoic Acid in Rat Conceptal Homogenates
    Hao Chen and Mont R. Juchau
    Drug Metabolism and Disposition March 1998, 26 (3) 222-228;
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    Modification of Paclitaxel Metabolism in a Cancer Patient by Induction of Cytochrome P450 3A4
    Bernard Monsarrat, Etienne Chatelut, Isabelle Royer, Paul Alvinerie, Joelle Dubois, Annik Dezeuse, Henri Roché, Suzy Cros, Michel Wright and Pierre Canal
    Drug Metabolism and Disposition March 1998, 26 (3) 229-233;
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    Effects of Retinoid Treatment of Rats on Hepatic Microsomal Metabolism and Cytochromes P450
    Stanley R. Howell, Michael A. Shirley and Edgar H. Ulm
    Drug Metabolism and Disposition March 1998, 26 (3) 234-239;
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    Pharmacokinetics and Plasma Protein Binding of Tamsulosin Hydrochloride in Rats, Dogs, and Humans
    Hiroshi Matsushima, Hidetaka Kamimura, Yoshiaki Soeishi, Takashi Watanabe, Saburo Higuchi and Michio Tsunoo
    Drug Metabolism and Disposition March 1998, 26 (3) 240-245;
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    Mechanisms for Covalent Binding of Benoxaprofen Glucuronide to Human Serum Albumin
    Y. Qiu, A. L. Burlingame and L. Z. Benet
    Drug Metabolism and Disposition March 1998, 26 (3) 246-256;
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    Inhibition of Methadone and BuprenorphineN-Dealkylations by Three HIV-1 Protease Inhibitors
    Christelle Iribarne, François Berthou, Dominique Carlhant, Yvonne Dreano, Daniel Picart, Françoise Lohezic and Christian Riche
    Drug Metabolism and Disposition March 1998, 26 (3) 257-260;
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    Cytochrome P450 2C9 Catalyzes IndomethacinO-Demethylation in Human Liver Microsomes
    Miki Nakajima, Tsuyoshi Inoue, Noriaki Shimada, Shogo Tokudome, Toshinori Yamamoto and Yukio Kuroiwa
    Drug Metabolism and Disposition March 1998, 26 (3) 261-266;
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    Immunochemical Comparison of 3′-Hydroxyacetanilide and Acetaminophen Binding in Mouse Liver
    William F. Salminen, Stephen M. Roberts, Neil R. Pumford and Jack A. Hinson
    Drug Metabolism and Disposition March 1998, 26 (3) 267-271;
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    Quantitative Comparison of Autoradioluminographic and Radiometric Tissue Distribution Studies Using Carbon-14 Labeled Xenobiotics
    Michael J. Potchoiba, Michael West and Mark R. Nocerini
    Drug Metabolism and Disposition March 1998, 26 (3) 272-277;
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    Isolation of a New Canine Cytochrome P450 cDNA from the Cytochrome P450 2C Subfamily (CYP2C41) and Evidence for Polymorphic Differences in Its Expression
    Joyce Blaisdell, Joyce A. Goldstein and Stephen A. Bai
    Drug Metabolism and Disposition March 1998, 26 (3) 278-283;

Short Communication

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    Expression of Two Different FMOs in Sheep Liver
    C. Longin-Sauvageon, V. Lattard, C. Lilaz-Michel, T. Buronfosse and E. Benoit
    Drug Metabolism and Disposition March 1998, 26 (3) 284-287;

Erratum

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    Correction for vol. 25, p. 1329
    Drug Metabolism and Disposition March 1998, 26 (3) 288-289;
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In this issue

Drug Metabolism and Disposition
Vol. 26, Issue 3
1 Mar 1998
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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