Evaluation of the Selectivity of In Vitro Probes and Suitability of Organic Solvents for the Measurement of Human Cytochrome P450 Monooxygenase Activities

Dean Hickman; Ji-Ping Wang; Yi Wang; Jashvant D. Unadkat

Article Information

vol. 26 no. 3 207-215

PubMed

9492382

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0090-9556

Online ISSN

1521-009X

History

Received May 20, 1997
Accepted November 18, 1997
Published online March 1, 1998.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

Dean Hickman1,
Ji-Ping Wang2,
Yi Wang and
Jashvant D. Unadkat

Department of Pharmaceutics, University of Washington

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: January 1999 to January 2022

	Abstract	Full	Pdf
Jan 1999	4	15	6
Feb 1999	4	16	8
Mar 1999	4	20	11
Apr 1999	0	7	1
May 1999	6	20	15
Jun 1999	2	11	10
Jul 1999	3	44	24
Aug 1999	2	14	14
Sep 1999	3	10	10
Oct 1999	2	11	11
Nov 1999	2	21	17
Dec 1999	0	16	18
Jan 2000	0	30	5
Feb 2000	7	27	14
Mar 2000	2	38	17
Apr 2000	0	14	16
May 2000	4	11	30
Jun 2000	3	35	28
Jul 2000	5	30	20
Aug 2000	7	27	31
Sep 2000	2	9	27
Oct 2000	4	30	30
Nov 2000	1	14	18
Dec 2000	2	9	16
Jan 2001	5	16	37
Feb 2001	6	12	36
Mar 2001	6	18	26
Apr 2001	2	28	16
May 2001	6	18	35
Jun 2001	14	22	15
Jul 2001	18	22	30
Aug 2001	19	24	38
Sep 2001	24	8	17
Oct 2001	12	30	24
Nov 2001	4	11	16
Dec 2001	5	8	20
Jan 2002	7	18	31
Feb 2002	11	18	25
Mar 2002	5	12	26
Apr 2002	8	30	34
May 2002	10	20	32
Jun 2002	11	14	20
Jul 2002	8	22	24
Aug 2002	15	17	29
Sep 2002	9	11	33
Oct 2002	7	30	33
Nov 2002	2	25	24
Dec 2002	5	18	30
Jan 2003	6	17	40
Feb 2003	11	21	59
Mar 2003	4	27	37
Apr 2003	7	28	40
May 2003	12	29	40
Jun 2003	16	20	25
Jul 2003	18	37	39
Aug 2003	14	32	53
Sep 2003	13	40	47
Oct 2003	37	44	47
Nov 2003	14	34	45
Dec 2003	12	31	18
Jan 2004	34	60	36
Feb 2004	19	55	51
Mar 2004	24	67	71
Apr 2004	23	44	42
May 2004	18	48	41
Jun 2004	27	58	52
Jul 2004	24	55	40
Aug 2004	29	52	21
Sep 2004	27	48	23
Oct 2004	23	98	39
Nov 2004	25	77	64
Dec 2004	42	65	21
Jan 2005	27	89	38
Feb 2005	18	53	32
Mar 2005	27	46	56
Apr 2005	24	36	44
May 2005	17	35	27
Jun 2005	13	33	28
Jul 2005	6	37	21
Aug 2005	8	27	27
Sep 2005	13	33	28
Oct 2005	17	28	32
Nov 2005	11	29	17
Dec 2005	9	36	29
Jan 2006	10	52	25
Feb 2006	7	55	25
Mar 2006	7	35	27
Apr 2006	3	34	18
May 2006	7	45	31
Jun 2006	9	32	18
Jul 2006	6	17	8
Aug 2006	15	13	22
Sep 2006	8	30	33
Oct 2006	12	21	22
Nov 2006	18	29	29
Dec 2006	20	18	32
Jan 2007	18	30	29
Feb 2007	16	35	22
Mar 2007	16	51	34
Apr 2007	16	41	20
May 2007	16	26	36
Jun 2007	15	21	35
Jul 2007	4	20	21
Aug 2007	11	14	16
Sep 2007	8	25	24
Oct 2007	5	25	24
Nov 2007	11	14	20
Dec 2007	4	15	16
Jan 2008	9	16	23
Feb 2008	11	18	30
Mar 2008	10	17	26
Apr 2008	4	15	27
May 2008	6	18	29
Jun 2008	8	13	19
Jul 2008	19	17	17
Aug 2008	11	12	24
Sep 2008	24	23	21
Oct 2008	14	24	19
Nov 2008	18	28	32
Dec 2008	7	8	13
Jan 2009	7	14	14
Feb 2009	8	10	14
Mar 2009	13	11	18
Apr 2009	10	20	15
May 2009	5	10	12
Jun 2009	6	22	20
Jul 2009	13	17	26
Aug 2009	16	16	24
Sep 2009	12	19	17
Oct 2009	20	11	22
Nov 2009	22	15	18
Dec 2009	39	11	20
Jan 2010	38	9	13
Feb 2010	40	13	21
Mar 2010	27	12	13
Apr 2010	44	37	24
May 2010	30	22	6
Jun 2010	37	42	30
Jul 2010	21	24	21
Aug 2010	15	11	12
Sep 2010	38	18	16
Oct 2010	34	30	30
Nov 2010	22	33	22
Dec 2010	38	21	18
Jan 2011	26	25	14
Feb 2011	35	51	13
Mar 2011	39	23	21
Apr 2011	35	13	21
May 2011	40	15	11
Jun 2011	30	16	17
Jul 2011	39	11	38
Aug 2011	33	31	30
Sep 2011	33	42	25
Oct 2011	27	25	26
Nov 2011	39	15	26
Dec 2011	20	27	18
Jan 2012	26	35	13
Feb 2012	26	33	12
Mar 2012	34	27	75
Apr 2012	32	44	32
May 2012	31	20	23
Jun 2012	36	35	29
Jul 2012	32	22	20
Aug 2012	29	17	31
Sep 2012	38	25	49
Oct 2012	34	17	29
Nov 2012	18	23	33
Dec 2012	30	18	25
Jan 2013	31	27	31
Feb 2013	33	15	22
Mar 2013	38	21	30
Apr 2013	35	20	28
May 2013	24	28	27
Jun 2013	25	11	13
Jul 2013	16	16	24
Aug 2013	17	7	11
Sep 2013	142	10	16
Oct 2013	361	8	13
Nov 2013	289	11	26
Dec 2013	18	6	15
Jan 2014	20	10	14
Feb 2014	20	11	9
Mar 2014	16	10	18
Apr 2014	73	21	20
May 2014	22	8	10
Jun 2014	22	8	13
Jul 2014	26	24	19
Aug 2014	22	6	12
Sep 2014	24	8	13
Oct 2014	19	22	16
Nov 2014	37	3	15
Dec 2014	20	8	10
Jan 2015	9	15	9
Feb 2015	16	10	10
Mar 2015	23	9	17
Apr 2015	20	12	20
May 2015	55	10	12
Jun 2015	19	15	21
Jul 2015	28	10	21
Aug 2015	15	10	42
Sep 2015	9	2	3
Oct 2015	24	11	10
Nov 2015	65	23	16
Dec 2015	19	13	10
Jan 2016	21	12	13
Feb 2016	18	9	8
Mar 2016	21	10	18
Apr 2016	21	12	11
May 2016	52	23	20
Jun 2016	29	16	14
Jul 2016	43	29	22
Aug 2016	41	19	13
Sep 2016	8	7	6
Oct 2016	3	20	6
Nov 2016	1	20	11
Dec 2016	2	9	5
Jan 2017	5	15	10
Feb 2017	4	25	9
Mar 2017	3	17	8
Apr 2017	5	16	12
May 2017	7	15	18
Jun 2017	9	9	18
Jul 2017	4	7	4
Aug 2017	1	43	20
Sep 2017	2	54	12
Oct 2017	1	67	20
Nov 2017	5	73	23
Dec 2017	1	424	17
Jan 2018	5	373	18
Feb 2018	3	224	15
Mar 2018	4	168	11
Apr 2018	8	106	19
May 2018	2	65	8
Jun 2018	2	58	8
Jul 2018	4	43	12
Aug 2018	4	29	6
Sep 2018	3	29	15
Oct 2018	2	75	6
Nov 2018	8	142	8
Dec 2018	88	33	9
Jan 2019	69	8	3
Feb 2019	82	5	10
Mar 2019	24	5	1
Apr 2019	19	4	1
May 2019	15	7	5
Jun 2019	13	4	5
Jul 2019	17	2	1
Aug 2019	10	4	4
Sep 2019	34	6	2
Oct 2019	23	2	1
Nov 2019	38	6	4
Dec 2019	38	13	2
Jan 2020	22	4	1
Feb 2020	19	2	0
Mar 2020	13	14	4
Apr 2020	32	5	2
May 2020	19	1	1
Jun 2020	19	1	0
Jul 2020	23	1	4
Aug 2020	8	1	3
Sep 2020	31	10	3
Oct 2020	27	3	3
Nov 2020	10	2	2
Dec 2020	25	14	2
Jan 2021	16	64	4
Feb 2021	12	46	1
Mar 2021	7	7	4
Apr 2021	32	5	1
May 2021	23	18	0
Jun 2021	32	38	4
Jul 2021	15	5	1
Aug 2021	13	46	4
Sep 2021	21	15	1
Oct 2021	27	8	1
Nov 2021	20	2	1
Dec 2021	32	9	0
Jan 2022	2	4	0