Metabolism of the Human Immunodeficiency Virus Protease Inhibitors Indinavir and Ritonavir by Human Intestinal Microsomes and Expressed Cytochrome P4503A4/3A5: Mechanism-Based Inactivation of Cytochrome P4503A by Ritonavir

	Abstract	Full	Pdf
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Jan 2000	2	23	8
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Sep 2001	9	28	24
Oct 2001	6	18	30
Nov 2001	3	16	21
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Jan 2002	0	16	23
Feb 2002	2	35	11
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Apr 2002	0	19	16
May 2002	2	19	19
Jun 2002	3	28	33
Jul 2002	3	36	24
Aug 2002	1	10	14
Sep 2002	3	23	26
Oct 2002	4	20	23
Nov 2002	5	35	19
Dec 2002	1	13	13
Jan 2003	1	26	28
Feb 2003	6	22	23
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Apr 2003	0	14	23
May 2003	2	32	41
Jun 2003	3	24	25
Jul 2003	11	34	24
Aug 2003	11	30	27
Sep 2003	13	40	14
Oct 2003	17	38	22
Nov 2003	15	28	19
Dec 2003	15	33	20
Jan 2004	22	42	30
Feb 2004	10	36	23
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Apr 2004	10	42	19
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Jun 2004	21	65	58
Jul 2004	21	37	19
Aug 2004	20	37	16
Sep 2004	25	45	31
Oct 2004	25	90	44
Nov 2004	21	62	22
Dec 2004	25	67	24
Jan 2005	33	64	40
Feb 2005	15	47	38
Mar 2005	10	40	33
Apr 2005	6	33	20
May 2005	13	36	21
Jun 2005	9	34	23
Jul 2005	22	39	20
Aug 2005	8	29	7
Sep 2005	8	34	16
Oct 2005	13	34	22
Nov 2005	11	43	16
Dec 2005	10	28	23
Jan 2006	9	22	12
Feb 2006	8	47	24
Mar 2006	10	71	18
Apr 2006	10	30	19
May 2006	23	48	20
Jun 2006	11	27	13
Jul 2006	14	20	20
Aug 2006	12	23	20
Sep 2006	8	22	13
Oct 2006	12	28	21
Nov 2006	14	44	24
Dec 2006	10	18	6
Jan 2007	8	12	18
Feb 2007	11	22	16
Mar 2007	7	42	28
Apr 2007	21	48	20
May 2007	19	29	25
Jun 2007	13	25	13
Jul 2007	13	16	14
Aug 2007	6	22	12
Sep 2007	10	33	29
Oct 2007	6	21	20
Nov 2007	12	28	18
Dec 2007	2	28	10
Jan 2008	7	23	9
Feb 2008	12	12	10
Mar 2008	9	49	22
Apr 2008	5	57	25
May 2008	8	46	16
Jun 2008	12	28	13
Jul 2008	5	37	18
Aug 2008	9	40	11
Sep 2008	16	26	32
Oct 2008	6	31	18
Nov 2008	10	53	22
Dec 2008	9	29	12
Jan 2009	8	22	16
Feb 2009	11	27	13
Mar 2009	12	28	16
Apr 2009	12	54	28
May 2009	10	41	28
Jun 2009	8	44	24
Jul 2009	9	40	18
Aug 2009	12	29	18
Sep 2009	9	26	19
Oct 2009	14	18	20
Nov 2009	6	12	12
Dec 2009	9	5	13
Jan 2010	30	22	18
Feb 2010	13	27	9
Mar 2010	16	42	20
Apr 2010	20	23	16
May 2010	37	36	23
Jun 2010	21	22	14
Jul 2010	23	24	15
Aug 2010	14	38	17
Sep 2010	22	40	24
Oct 2010	31	35	28
Nov 2010	22	34	25
Dec 2010	33	34	19
Jan 2011	26	22	16
Feb 2011	26	20	16
Mar 2011	25	42	34
Apr 2011	20	43	29
May 2011	23	27	31
Jun 2011	15	34	19
Jul 2011	21	34	36
Aug 2011	15	28	19
Sep 2011	16	28	29
Oct 2011	17	30	25
Nov 2011	30	37	36
Dec 2011	28	41	32
Jan 2012	18	45	25
Feb 2012	14	22	29
Mar 2012	44	54	41
Apr 2012	25	48	53
May 2012	21	26	37
Jun 2012	9	39	43
Jul 2012	22	24	37
Aug 2012	19	21	28
Sep 2012	29	14	26
Oct 2012	21	28	42
Nov 2012	14	24	30
Dec 2012	23	35	31
Jan 2013	21	24	27
Feb 2013	28	48	23
Mar 2013	34	19	22
Apr 2013	32	30	34
May 2013	38	21	28
Jun 2013	12	17	19
Jul 2013	12	12	15
Aug 2013	9	6	15
Sep 2013	24	10	24
Oct 2013	28	9	19
Nov 2013	15	8	17
Dec 2013	15	17	23
Jan 2014	14	9	17
Feb 2014	23	17	26
Mar 2014	22	28	45
Apr 2014	20	21	39
May 2014	15	23	27
Jun 2014	19	16	17
Jul 2014	21	29	26
Aug 2014	8	44	19
Sep 2014	15	13	8
Oct 2014	19	24	18
Nov 2014	28	26	9
Dec 2014	13	22	17
Jan 2015	18	21	15
Feb 2015	10	17	16
Mar 2015	24	30	26
Apr 2015	17	22	10
May 2015	22	20	16
Jun 2015	12	9	10
Jul 2015	15	22	8
Aug 2015	16	29	11
Sep 2015	14	12	5
Oct 2015	11	19	18
Nov 2015	12	13	9
Dec 2015	13	19	9
Jan 2016	17	7	10
Feb 2016	7	7	13
Mar 2016	22	19	19
Apr 2016	26	28	17
May 2016	16	6	16
Jun 2016	12	9	11
Jul 2016	7	11	13
Aug 2016	15	5	9
Sep 2016	11	12	12
Oct 2016	10	723	10
Nov 2016	11	1222	9
Dec 2016	5	391	10
Jan 2017	16	51	15
Feb 2017	5	395	13
Mar 2017	8	859	17
Apr 2017	3	253	14
May 2017	11	31	24
Jun 2017	3	24	9
Jul 2017	5	16	13
Aug 2017	3	19	9
Sep 2017	5	34	7
Oct 2017	2	43	18
Nov 2017	5	66	11
Dec 2017	9	37	15
Jan 2018	12	32	13
Feb 2018	0	28	10
Mar 2018	9	35	5
Apr 2018	6	23	12
May 2018	2	26	12
Jun 2018	6	24	12
Jul 2018	8	22	19
Aug 2018	2	26	12
Sep 2018	1	19	10
Oct 2018	5	39	7
Nov 2018	3	27	10
Dec 2018	17	9	3
Jan 2019	32	8	4
Feb 2019	39	5	1
Mar 2019	19	7	3
Apr 2019	21	4	3
May 2019	33	5	4
Jun 2019	25	3	6
Jul 2019	17	6	3
Aug 2019	26	17	12
Sep 2019	37	9	4
Oct 2019	67	9	9
Nov 2019	34	5	3
Dec 2019	29	12	4
Jan 2020	28	8	0
Feb 2020	39	11	6
Mar 2020	72	11	3
Apr 2020	78	5	7
May 2020	45	7	6
Jun 2020	53	3	1
Jul 2020	15	4	2
Aug 2020	31	4	6
Sep 2020	30	3	1
Oct 2020	33	5	3
Nov 2020	41	1	1
Dec 2020	54	5	3
Jan 2021	21	39	6
Feb 2021	25	28	2
Mar 2021	33	8	3
Apr 2021	45	5	2
May 2021	52	13	1
Jun 2021	28	16	2
Jul 2021	24	6	3