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Metabolism of Delavirdine, a Human Immunodeficiency Virus Type-1 Reverse Transcriptase Inhibitor, by Microsomal Cytochrome P450 in Humans, Rats, and Other Species: Probable Involvement of CYP2D6 and CYP3A

Richard L. Voorman, Stephen M. Maio, Michael J. Hauer, Philip E. Sanders, N. Ann Payne and Mark J. Ackland
Drug Metabolism and Disposition July 1998, 26 (7) 631-639;

Article Information

vol. 26 no. 7 631-639
PubMed 
9660845
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 4, 1997
  • Accepted March 4, 1998
  • Published online July 1, 1998.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Richard L. Voorman,
  2. Stephen M. Maio,
  3. Michael J. Hauer,
  4. Philip E. Sanders,
  5. N. Ann Payne and
  6. Mark J. Ackland1
  1. Drug Metabolism Research, Pharmacia and Upjohn
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    Research ArticleArticle

    Metabolism of Delavirdine, a Human Immunodeficiency Virus Type-1 Reverse Transcriptase Inhibitor, by Microsomal Cytochrome P450 in Humans, Rats, and Other Species: Probable Involvement of CYP2D6 and CYP3A

    Richard L. Voorman, Stephen M. Maio, Michael J. Hauer, Philip E. Sanders, N. Ann Payne and Mark J. Ackland
    Drug Metabolism and Disposition July 1, 1998, 26 (7) 631-639;
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