Table of Contents

Articles

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  Disposition and Pharmacokinetics of Phenethyl Isothiocyanate and 6-Phenylhexyl Isothiocyanate in F344 Rats

  C. Clifford Conaway, Ding Jiao, Toshiyuki Kohri, Leonard Liebes and Fung-Lung Chung

  Drug Metabolism and Disposition January 1999, 27 (1) 13-20;
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  Animal Pharmacokinetics of the Tumor Necrosis Factor Receptor-Immunoglobulin Fusion Protein Lenercept and Their Extrapolation to Humans

  Wolfgang F. Richter, Harald Gallati and Claus-Dieter Schiller

  Drug Metabolism and Disposition January 1999, 27 (1) 21-25;
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  Glucuronidation of R- andS-Ketoprofen, Acetaminophen, and Diflunisal by Liver Microsomes of Adjuvant-Induced Arthritic Rats

  Christine J. Meunier and Roger K. Verbeeck

  Drug Metabolism and Disposition January 1999, 27 (1) 26-31;
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  Rapid Liquid Chromatography with Tandem Mass Spectrometry-Based Screening Procedures for Studies on the Biotransformation of Drug Candidates

  C. L. Fernández-Metzler, K. G. Owens*, T. A. Baillie and R. C. King

  Drug Metabolism and Disposition January 1999, 27 (1) 32-40;
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  Nonlinear Pharmacokinetics of Efavirenz (DMP-266), a Potent HIV-1 Reverse Transcriptase Inhibitor, in Rats and Monkeys

  Suresh K. Balani, Laura R. Kauffman, Florencia A. deLuna and Jiunn H. Lin

  Drug Metabolism and Disposition January 1999, 27 (1) 41-45;
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  Species and Sex Differences in Expression of Flavin-Containing Monooxygenase Form 3 in Liver and Kidney Microsomes

  Sharon L. Ripp, Kiyoshi Itagaki, Richard M. Philpot and Adnan A. Elfarra

  Drug Metabolism and Disposition January 1999, 27 (1) 46-52;
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  EDTA-Resistant and Sensitive Phosphotriesterase Activities Associated with Albumin and Lipoproteins in Rabbit Serum

  Miguel A. Sogorb, Inés Sánchez, Manuel López-Rivadulla, Virtudes Céspedes and Eugenio Vilanova

  Drug Metabolism and Disposition January 1999, 27 (1) 53-59;
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  Aldose Reductase Catalyzes the Oxidation of Naphthalene-1,2-Dihydrodiol for the Formation ofOrtho-Naphthoquinone

  Katsumi Sugiyama, Tao-Chin Lin Wang, John T. Simpson, Libaniel Rodriguez, Peter F. Kador and Sanai Sato

  Drug Metabolism and Disposition January 1999, 27 (1) 60-67;
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  Diminished CYP2E1 Expression and Formation of 2-S-Glutathionyl Acetate, a Glutathione Conjugate Derived from 1,1-Dichloroethylene Epoxide, in Murine Lung Tumors

  Poh-Gek Forkert, Alvin M. Malkinson, Pamela Rice and Madeleine Moussa

  Drug Metabolism and Disposition January 1999, 27 (1) 68-73;
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  Metabolic Disposition of a Monoterpene Ketone, Piperitenone, in Rats: Evidence for the Formation of a Known Toxin,p-cresol

  K. Madhava Madyastha and Nilesh W. Gaikwad

  Drug Metabolism and Disposition January 1999, 27 (1) 74-80;
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  Role of Plasma Protein Binding on Renal Metabolism and Dynamics of Furosemide in the Rabbit

  Vincent Pichette, David Geadah and Patrick du Souich

  Drug Metabolism and Disposition January 1999, 27 (1) 81-85;
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  In Vitro Metabolism of the HIV-1 Protease Inhibitor ABT-378: Species Comparison and Metabolite Identification

  Gondi N. Kumar, Venkata Jayanti, Ronald D. Lee, David N. Whittern, John Uchic, Samuel Thomas, Paulette Johnson, Brian Grabowski, Hing Sham, David Betebenner, Dale J. Kempf and Jon F. Denissen

  Drug Metabolism and Disposition January 1999, 27 (1) 86-91;
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  A Unique Tertiary Amine N-Oxide Reduction System Composed of Quinone Reductase and Heme in Rat Liver Preparations

  Shigeyuki Kitamura, Kazumi Sugihara and Kiyoshi Tatsumi

  Drug Metabolism and Disposition January 1999, 27 (1) 92-97;
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  Detection of a Novel Cytochrome P-450 1A2 polymorphism (F21L) in Chinese

  Jin-ding Huang, Wei-Chung Guo, Ming-Derg Lai, Yueleong Leon Guo and George H. Lambert

  Drug Metabolism and Disposition January 1999, 27 (1) 98-101;
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  Eight Inhibitory Monoclonal Antibodies Define the Role of Individual P-450s in Human Liver Microsomal Diazepam, 7-Ethoxycoumarin, and Imipramine Metabolism

  Tian J. Yang, Kristopher W. Krausz, Yang Sai, Frank J. Gonzalez and Harry V. Gelboin

  Drug Metabolism and Disposition January 1999, 27 (1) 102-109;
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  Heterogeneity in Systemic Availability of Ondansetron and Granisetron following Oral Administration

  B. W. Corrigan, B. Nicholls, B. Thakrar, R. Lam, C. Grosse, J. Alianti and J. L. Palmer

  Drug Metabolism and Disposition January 1999, 27 (1) 110-112;
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  First-Pass Disposition of (−)-6-Aminocarbovir in Rats. I. Prodrug Activation May Be Limited by Access to Enzyme

  Yandong Wen, Rory P. Remmel and Cheryl L. Zimmerman

  Drug Metabolism and Disposition January 1999, 27 (1) 113-121;
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  Prolactin Increases the Hepatic Content of μ-Class Subunits of Glutathione S-Transferase in the Rat

  Marcelo G. Luquita, Viviana A. Catania, Enrique J. Sánchez-Pozzi, Mary Vore and Aldo D. Mottino

  Drug Metabolism and Disposition January 1999, 27 (1) 122-124;
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  In Vitro Metabolism of the M1-Muscarinic Agonist 5-(2-Ethyl-2H-tetrazol-5-yl)-1-methyl-1,2,3,6-tetrahydropyridine by Human Hepatic Cytochromes P-450 Determined at pH 7.4 and 8.5

  Klaus Gjervig Jensen and Lars Dalgaard

  Drug Metabolism and Disposition January 1999, 27 (1) 125-132;
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  Inhibition of Human Aldehyde Dehydrogenase 1 by the 4-Hydroxycyclophosphamide Degradation Product Acrolein

  Song Ren, Thomas F. Kalhorn and John T. Slattery

  Drug Metabolism and Disposition January 1999, 27 (1) 133-137;
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  Comparative Metabolism and Disposition of Gemfibrozil in Male and Female Sprague-Dawley Rats and Syrian golden Hamsters

  Kelly J. Dix, Donna P. Coleman and A. Robert Jeffcoat

  Drug Metabolism and Disposition January 1999, 27 (1) 138-146;
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  Isolation and identification of novel metabolites of gemfibrozil in rat urine

  Brian F. Thomas, Jason P. Burgess, Donna P. Coleman, Nicole M. Scheffler, A. Robert Jeffcoat and Kelly J. Dix

  Drug Metabolism and Disposition January 1999, 27 (1) 147-157;