Table of Contents

Articles

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  Detection of Quantitative Trait Loci Affecting Caffeine Metabolism by Interval Mapping in a Genome-Wide Scan of C3H/HeJ × APN F₂ Mice

  William L. Casley, J. Allan Menzies, Larry W. Whitehouse and Thomas W. Moon

  Drug Metabolism and Disposition December 1999, 27 (12) 1375-1380;
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  Azelastine N-Demethylation by Cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in Human Liver Microsomes: Evaluation of Approach to Predict the Contribution of Multiple CYPs

  Miki Nakajima, Sumika Nakamura, Shogo Tokudome, Noriaki Shimada, Hiroshi Yamazaki and Tsuyoshi Yokoi

  Drug Metabolism and Disposition December 1999, 27 (12) 1381-1391;
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  Modulation of Hepatic CYP2A1, CYP2C11, and CYP3A9 Expression in Adult Rats by Neonatal Administration of Tamoxifen

  Masahiko Kawai, Stelvio M. Bandiera, Thomas K. H. Chang, Frederique M. Poulet, Paul M. Vancutsem and Gail D. Bellward

  Drug Metabolism and Disposition December 1999, 27 (12) 1392-1398;
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  Enhancement of Platinum-Drug Cytotoxicity in a Human Head and Neck Squamous Cell Carcinoma Line and its Platinum-Resistant Variant by Liposomal Amphotericin B and Phospholipase A2-II

  Peter J. Ferguson, Catherine Currie and Mark D. Vincent

  Drug Metabolism and Disposition December 1999, 27 (12) 1399-1405;
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  Absorption, Distribution, Metabolism, and Excretion of Donepezil (Aricept) after a Single Oral Administration to Rat

  Kenji Matsui, Mannen Mishima, Yasushi Nagai, Teruaki Yuzuriha and Tsutomu Yoshimura

  Drug Metabolism and Disposition December 1999, 27 (12) 1406-1414;
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  Drug Metabolizing Capacity of Cryopreserved Human, Rat, and Mouse Liver Parenchymal Cells in Suspension

  Pablo Steinberg, Thomas Fischer, Sandra Kiulies, Katja Biefang, Karl-Ludwig Platt, Franz Oesch, Thomas Böttger, Clemens Bulitta, Peter Kempf and Jan Hengstler

  Drug Metabolism and Disposition December 1999, 27 (12) 1415-1422;
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  Effect of Selective Phase II Enzyme Inducers on Glucuronidation of Benoxaprofen in Rats

  Jennifer Q. Dong, Amy S. Etheridge and Philip C. Smith

  Drug Metabolism and Disposition December 1999, 27 (12) 1423-1428;
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  Role of Human CYP2B6 in S-MephobarbitalN-Demethylation

  Kaoru Kobayashi, Seiji Abe, Miki Nakajima, Noriaki Shimada, Masayoshi Tani, Kan Chiba and Toshinori Yamamoto

  Drug Metabolism and Disposition December 1999, 27 (12) 1429-1433;
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  Biotransformation of Nevirapine, a Non-nucleoside HIV-1 Reverse Transcriptase Inhibitor, in Mice, Rats, Rabbits, Dogs, Monkeys, and Chimpanzees

  Paul S. Riska, David P. Joseph, Roger M. Dinallo, Walter C. Davidson, James J. Keirns and Susan E. Hattox

  Drug Metabolism and Disposition December 1999, 27 (12) 1434-1447;
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  Residence Times and Half-Lives of Nicotine Metabolites in Rat Brain after Acute Peripheral Administration of [2′-¹⁴C]Nicotine

  Omar Ghosheh, Linda P. Dwoskin, Wen-Kui Li and Peter A. Crooks

  Drug Metabolism and Disposition December 1999, 27 (12) 1448-1455;
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  Metabolism and Disposition of [¹⁴C]1-Nitronaphthalene in Male Sprague-Dawley Rats

  Jason S. Halladay, John-Michael Sauer and I. Glenn Sipes

  Drug Metabolism and Disposition December 1999, 27 (12) 1456-1465;
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  Up-Regulation of Glutathione S-Transferase Activity in Enterocytes of Young Children

  John P. Gibbs, Chris A. Liacouras, Robert N. Baldassano and John T. Slattery

  Drug Metabolism and Disposition December 1999, 27 (12) 1466-1469;
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  Toxicokinetics of 1,2-Diethylbenzene in Male Sprague-Dawley Rats—Part 1: Excretion and Metabolism of [¹⁴C]1,2-Diethylbenzene

  Jean-Paul Payan, Dominique Beydon, Benoît Cossec, André Ensminger, Jean-Paul Fabry and Elisabeth Ferrari

  Drug Metabolism and Disposition December 1999, 27 (12) 1470-1478;
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  A Method for Estimating Pharmacokinetic Risks of Concentration-Dependent Drug Interactions from Preclinical Data

  Murali Ramanathan

  Drug Metabolism and Disposition December 1999, 27 (12) 1479-1487;
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  Characterization of the In Vitro Biotransformation of the HIV-1 Reverse Transcriptase Inhibitor Nevirapine by Human Hepatic Cytochromes P-450

  David A. Erickson, Gary Mather, William F. Trager, Rene H. Levy and James J. Keirns

  Drug Metabolism and Disposition December 1999, 27 (12) 1488-1495;
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  Pharmacokinetics of Orally Administered Desferrithiocin Analogs in Cebus apella Primates

  Raymond J. Bergeron, William R. Weimar and Jan Wiegand

  Drug Metabolism and Disposition December 1999, 27 (12) 1496-1498;
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  Absorption, Metabolism, and Disposition of 1,3-Diphenyl-1-Triazene in Rats and Mice after Oral, i.v., and Dermal Administration

  James M. Mathews and Kristi S. De Costa

  Drug Metabolism and Disposition December 1999, 27 (12) 1499-1504;
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  Ethynylestradiol-Mediated Induction of HepaticCYP3A9 in Female Rats: Implication for Cyclosporine Metabolism

  Walter Jäger, Maria Almira Correia, Lester M. Bornheim, Axel Mahnke, Walter G. Hanstein, Linlong Xue and Leslie Z. Benet

  Drug Metabolism and Disposition December 1999, 27 (12) 1505-1511;
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  Induction of the Metabolism of Midazolam by Rifampin in Cultured Porcine Hepatocytes: Preliminary Evidence for CYP3A Isoforms in Pigs

  Vinayak P. Hosagrahara, Linda K. Hansen and Rory P. Remmel

  Drug Metabolism and Disposition December 1999, 27 (12) 1512-1518;