Drug Metabolism and Disposition: 27 (12)

Cover Caption

Casley et al. report on a genome-wide scan for quantitative trait loci affecting caffeine metabolism using an interval mapping approach on an F₂ intercross population of APN and C3H/HeJ inbred mice. See related article by Casley et al. on page 1375 of this issue.

In this issue

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUC_I/AUC) RATIOS
In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

More...

Main menu

User menu

Search

Cover Caption

In this issue

Jump to

Navigate

More Information

ASPET's Other Journals