Table of Contents

Articles

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  Metabolism of Retinaldehyde Isomers in Pregnant Rats: 13-cis- and all-trans-Retinaldehyde, but not 9-cis-Retinaldehyde, Yield Very Similar Patterns of Retinoid Metabolites

  Jörn Oliver Sass, Georg Tzimas, Mohamed M.A. Elmazar and Heinz Nau

  Drug Metabolism and Disposition March 1999, 27 (3) 317-321;
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  Involvement of Cytochromes P-450 2E1 and 3A4 in the 5-Hydroxylation of Salicylate in Humans

  Isabelle Dupont, François Berthou, Pierre Bodenez, Louis Bardou, Caroline Guirriec, Nathalie Stephan, Yvonne Dreano and Danièle Lucas

  Drug Metabolism and Disposition March 1999, 27 (3) 322-326;
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  Effect of Cryopreservation on Cytochrome P-450 Enzyme Induction in Cultured Rat Hepatocytes

  Ajay Madan, Ryan DeHaan, Dan Mudra, Kathy Carroll, Edward LeCluyse and Andrew Parkinson

  Drug Metabolism and Disposition March 1999, 27 (3) 327-335;
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  Lack of Zonal Uptake of Estrone Sulfate in Enriched Periportal and Perivenous Isolated Rat Hepatocytes

  Eugene Tan, Rommel G. Tirona and K. Sandy Pang

  Drug Metabolism and Disposition March 1999, 27 (3) 336-341;
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  Metabolism of the New Liposomal Anticancer Drug N⁴-Octadecyl-1-β-D-Arabinofuranosylcytosine in Mice

  Sibylle K. M. Koller-Lucae, Marc J.-F. Suter, Katharina M. Rentsch, Herbert Schott and Reto A. Schwendener

  Drug Metabolism and Disposition March 1999, 27 (3) 342-350;
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  Glutathione Conjugation of Trichloroethylene in Human Liver and Kidney: Kinetics and Individual Variation

  Lawrence H. Lash, John C. Lipscomb, David A. Putt and Jean C. Parker

  Drug Metabolism and Disposition March 1999, 27 (3) 351-359;
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  Cytochrome P-450 1A1 Expression in Human Small Bowel: Interindividual Variation and Inhibition by Ketoconazole

  Mary F. Paine, Phyllissa Schmiedlin-Ren and Paul B. Watkins

  Drug Metabolism and Disposition March 1999, 27 (3) 360-364;
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  Studies on Cytochrome P-450-Mediated Bioactivation of Diclofenac in Rats and in Human Hepatocytes: Identification of Glutathione Conjugated Metabolites

  Wei Tang, Ralph A. Stearns, Stelvio M. Bandiera, Yong Zhang, Conrad Raab, Matthew P. Braun, Dennis C. Dean, Jianmei Pang, Kwan H. Leung, George A. Doss, John R. Strauss, Gloria Y. Kwei, Thomas H. Rushmore, Shuet-Hing L. Chiu and Thomas A. Baillie

  Drug Metabolism and Disposition March 1999, 27 (3) 365-372;
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  Distribution Kinetics of Salicylic Acid in the Dual-Perfused Rat Liver Preparation

  Selma Sahin and Malcolm Rowland

  Drug Metabolism and Disposition March 1999, 27 (3) 373-378;
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  Induction of CYP1A2 by Phenobarbital in the Livers of Aryl Hydrocarbon-Responsive and -Nonresponsive Mice

  Tsutomu Sakuma, Miwako Ohtake, Yoko Katsurayama, Kanokwan Jarukamjorn and Nobuo Nemoto

  Drug Metabolism and Disposition March 1999, 27 (3) 379-384;
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  G169R Mutation Diminishes the Metabolic Activity of CYP2D6 in Chinese

  Su-Lan Wang, Ming-Derg Lai and Jin-ding Huang

  Drug Metabolism and Disposition March 1999, 27 (3) 385-388;
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  The Aromatase Inactivator 4-Hydroxyandrostenedione (4-OH-A) Inhibits Tamoxifen Metabolism by Rat Hepatic Cytochrome P-450 3A: Potential for Drug-Drug Interaction of Tamoxifen and 4-OH-A in Combined Anti-Breast Cancer Therapy

  Shangara S. Dehal, Angela M. H. Brodie and David Kupfer

  Drug Metabolism and Disposition March 1999, 27 (3) 389-394;
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  Quantitative Prediction of Metabolic Inhibition of Midazolam by Itraconazole and Ketoconazole in Rats: Implication of Concentrative Uptake of Inhibitors into Liver

  Katsuhiro Yamano, Koujirou Yamamoto, Hajime Kotaki, Yasufumi Sawada and Tatsuji Iga

  Drug Metabolism and Disposition March 1999, 27 (3) 395-402;
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  Oxidative Bioactivation of the Lactol Prodrug of A Lactone Cyclooxygenase-2 Inhibitor

  Deborah A. Nicoll-Griffith, Jean-Pierre Falgueyret, José M. Silva, Pierre-Emmanuel Morin, Laird Trimble, Chi-C. Chan, Sophie Clas, Serge Leger, Zhaoyin Wang, James A. Yergey and Denis Riendeau

  Drug Metabolism and Disposition March 1999, 27 (3) 403-409;
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  The 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor Fluvastatin: Effect on Human Cytochrome P-450 and Implications for Metabolic Drug Interactions

  Volker Fischer, Laurie Johanson, Francis Heitz, Robert Tullman, Elizabeth Graham, Jean-Pierre Baldeck and William T. Robinson

  Drug Metabolism and Disposition March 1999, 27 (3) 410-416;
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  The Effect of Fluconazole on Cyclophosphamide Metabolism in Children

  S. M. Yule, D. Walker, M. Cole, L. McSorley, S. Cholerton, A. K. Daly, A.D.J. Pearson and A. V. Boddy

  Drug Metabolism and Disposition March 1999, 27 (3) 417-421;
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  Aldehyde Oxidase-Dependent Marked Species Difference in Hepatic Metabolism of the Sedative-Hypnotic, Zaleplon, Between Monkeys and Rats

  Kosuke Kawashima, Kenichi Hosoi, Takeshi Naruke, Toshiharu Shiba, Masataka Kitamura and Tadashi Watabe

  Drug Metabolism and Disposition March 1999, 27 (3) 422-428;