The Aromatase Inactivator 4-Hydroxyandrostenedione (4-OH-A) Inhibits Tamoxifen Metabolism by Rat Hepatic Cytochrome P-450 3A: Potential for Drug-Drug Interaction of Tamoxifen and 4-OH-A in Combined Anti-Breast Cancer Therapy

	Abstract	Full	Pdf
Mar 1999	25	29	22
Apr 1999	11	10	6
May 1999	0	12	7
Jun 1999	5	6	3
Jul 1999	0	6	4
Aug 1999	1	6	4
Sep 1999	3	5	2
Oct 1999	1	5	0
Nov 1999	1	11	4
Dec 1999	4	11	2
Jan 2000	1	8	0
Feb 2000	1	3	2
Mar 2000	2	14	12
Apr 2000	2	0	0
May 2000	0	5	4
Jun 2000	2	4	18
Jul 2000	1	11	8
Aug 2000	2	4	8
Sep 2000	4	7	11
Oct 2000	1	41	27
Nov 2000	1	29	10
Dec 2000	1	10	5
Jan 2001	1	11	6
Feb 2001	1	12	8
Mar 2001	4	5	5
Apr 2001	3	5	8
May 2001	1	9	5
Jun 2001	0	7	6
Jul 2001	3	8	4
Aug 2001	1	2	5
Sep 2001	0	7	3
Oct 2001	0	5	5
Nov 2001	3	3	1
Dec 2001	0	8	2
Jan 2002	2	9	2
Feb 2002	2	12	6
Mar 2002	2	17	4
Apr 2002	0	15	7
May 2002	0	10	7
Jun 2002	0	10	5
Jul 2002	3	11	5
Aug 2002	2	8	5
Sep 2002	7	2	2
Oct 2002	16	1	10
Nov 2002	0	6	6
Dec 2002	0	2	1
Jan 2003	2	8	10
Feb 2003	2	6	9
Mar 2003	3	12	5
Apr 2003	5	11	9
May 2003	0	9	8
Jun 2003	1	5	7
Jul 2003	6	16	3
Aug 2003	12	17	5
Sep 2003	3	14	6
Oct 2003	8	43	12
Nov 2003	6	26	5
Dec 2003	6	23	5
Jan 2004	15	35	6
Feb 2004	5	17	6
Mar 2004	11	26	6
Apr 2004	12	41	9
May 2004	13	16	6
Jun 2004	29	28	11
Jul 2004	17	35	10
Aug 2004	20	35	6
Sep 2004	22	37	5
Oct 2004	23	48	13
Nov 2004	25	47	21
Dec 2004	38	43	9
Jan 2005	26	40	20
Feb 2005	21	47	12
Mar 2005	23	33	11
Apr 2005	12	18	8
May 2005	16	27	3
Jun 2005	12	36	4
Jul 2005	14	28	5
Aug 2005	6	24	7
Sep 2005	7	25	8
Oct 2005	7	15	5
Nov 2005	7	21	7
Dec 2005	4	22	1
Jan 2006	0	25	7
Feb 2006	3	26	3
Mar 2006	4	28	6
Apr 2006	1	20	5
May 2006	0	14	6
Jun 2006	4	15	4
Jul 2006	0	10	1
Aug 2006	2	16	2
Sep 2006	2	9	5
Oct 2006	3	13	4
Nov 2006	10	12	5
Dec 2006	4	13	4
Jan 2007	8	18	7
Feb 2007	4	19	3
Mar 2007	3	30	7
Apr 2007	4	14	5
May 2007	2	18	2
Jun 2007	2	24	6
Jul 2007	2	24	3
Aug 2007	3	39	2
Sep 2007	2	30	7
Oct 2007	7	103	10
Nov 2007	5	41	6
Dec 2007	1	32	4
Jan 2008	2	45	5
Feb 2008	5	35	5
Mar 2008	5	34	12
Apr 2008	2	40	8
May 2008	1	23	6
Jun 2008	1	17	5
Jul 2008	2	17	4
Aug 2008	5	5	2
Sep 2008	4	18	7
Oct 2008	3	16	5
Nov 2008	6	19	13
Dec 2008	1	18	3
Jan 2009	2	18	15
Feb 2009	4	22	4
Mar 2009	3	16	4
Apr 2009	4	14	7
May 2009	6	14	0
Jun 2009	5	15	10
Jul 2009	3	19	8
Aug 2009	3	6	4
Sep 2009	6	9	3
Oct 2009	5	6	3
Nov 2009	6	7	4
Dec 2009	9	4	2
Jan 2010	9	10	4
Feb 2010	18	7	5
Mar 2010	17	9	7
Apr 2010	11	20	5
May 2010	4	13	4
Jun 2010	6	15	7
Jul 2010	5	27	17
Aug 2010	3	14	3
Sep 2010	5	15	3
Oct 2010	7	9	1
Nov 2010	7	4	2
Dec 2010	4	18	4
Jan 2011	3	12	2
Feb 2011	6	15	2
Mar 2011	17	17	4
Apr 2011	4	24	3
May 2011	7	12	5
Jun 2011	5	17	8
Jul 2011	7	16	10
Aug 2011	15	16	4
Sep 2011	16	9	6
Oct 2011	11	12	2
Nov 2011	10	14	5
Dec 2011	13	23	10
Jan 2012	16	13	7
Feb 2012	13	7	3
Mar 2012	12	13	6
Apr 2012	7	11	13
May 2012	8	10	5
Jun 2012	11	13	7
Jul 2012	7	11	5
Aug 2012	9	5	9
Sep 2012	8	3	6
Oct 2012	10	8	12
Nov 2012	11	11	13
Dec 2012	9	15	5
Jan 2013	20	13	3
Feb 2013	22	13	4
Mar 2013	12	9	5
Apr 2013	28	7	11
May 2013	16	5	6
Jun 2013	4	6	5
Jul 2013	8	4	6
Aug 2013	2	2	4
Sep 2013	8	2	9
Oct 2013	5	2	2
Nov 2013	7	3	6
Dec 2013	5	5	7
Jan 2014	3	1	4
Feb 2014	4	2	3
Mar 2014	11	2	8
Apr 2014	2	3	5
May 2014	1	2	4
Jun 2014	3	3	4
Jul 2014	7	10	3
Aug 2014	0	9	1
Sep 2014	0	20	6
Oct 2014	8	8	3
Nov 2014	9	9	7
Dec 2014	3	3	4
Jan 2015	7	5	0
Feb 2015	0	10	5
Mar 2015	7	10	4
Apr 2015	4	6	2
May 2015	3	1	3
Jun 2015	9	5	3
Jul 2015	6	5	3
Aug 2015	2	3	9
Sep 2015	4	3	4
Oct 2015	2	1	1
Nov 2015	1	1	2
Dec 2015	3	2	3
Jan 2016	2	9	3
Feb 2016	1	4	6
Mar 2016	2	2	10
Apr 2016	0	5	3
May 2016	3	3	5
Jun 2016	1	0	1
Jul 2016	0	3	2
Aug 2016	0	5	7
Sep 2016	0	1	2
Oct 2016	2	5	3
Nov 2016	0	1	3
Dec 2016	1	3	5
Jan 2017	1	9	4
Feb 2017	0	8	2
Mar 2017	0	2	1
Apr 2017	1	5	2
May 2017	0	8	2
Jun 2017	0	5	2
Jul 2017	1	3	3
Aug 2017	0	18	12
Sep 2017	0	16	9
Oct 2017	2	16	3
Nov 2017	2	14	4
Dec 2017	0	12	1
Jan 2018	0	8	2
Feb 2018	0	9	0
Mar 2018	1	9	5
Apr 2018	0	8	4
May 2018	0	15	5
Jun 2018	0	9	2
Jul 2018	0	7	10
Aug 2018	0	2	0
Sep 2018	0	2	3
Oct 2018	0	5	2
Nov 2018	0	3	1
Dec 2018	4	2	1
Jan 2019	5	0	1
Feb 2019	8	0	0
Mar 2019	5	0	0
Apr 2019	10	0	0
May 2019	6	2	2
Jun 2019	1	0	4
Jul 2019	8	1	0
Aug 2019	10	0	0
Sep 2019	9	0	0
Oct 2019	8	0	0
Nov 2019	7	0	0
Dec 2019	16	1	1
Jan 2020	7	1	1
Feb 2020	10	0	0
Mar 2020	7	3	0
Apr 2020	9	0	0
May 2020	14	2	0
Jun 2020	3	0	0
Jul 2020	3	0	0
Aug 2020	2	0	1
Sep 2020	3	0	0
Oct 2020	6	0	0
Nov 2020	13	0	0
Dec 2020	9	0	0
Jan 2021	5	1	0
Feb 2021	4	1	0
Mar 2021	17	1	0
Apr 2021	31	1	0
May 2021	9	1	0
Jun 2021	15	1	0
Jul 2021	6	1	0
Aug 2021	7	1	0
Sep 2021	5	1	0
Oct 2021	16	1	0
Nov 2021	25	1	0
Dec 2021	8	1	0
Jan 2022	5	1	0
Feb 2022	10	1	0
Mar 2022	8	2	0
Apr 2022	6	1	0
May 2022	1	0	0