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Cytochrome P-450 3A and 2D6 Catalyze OrthoHydroxylation of 4-Hydroxytamoxifen and 3-Hydroxytamoxifen (Droloxifene) Yielding Tamoxifen Catechol: Involvement of Catechols in Covalent Binding to Hepatic Proteins

Shangara S. Dehal and David Kupfer
Drug Metabolism and Disposition June 1999, 27 (6) 681-688;
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Research ArticleArticle

Cytochrome P-450 3A and 2D6 Catalyze OrthoHydroxylation of 4-Hydroxytamoxifen and 3-Hydroxytamoxifen (Droloxifene) Yielding Tamoxifen Catechol: Involvement of Catechols in Covalent Binding to Hepatic Proteins

Shangara S. Dehal and David Kupfer
Drug Metabolism and Disposition June 1, 1999, 27 (6) 681-688;
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