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Research ArticleArticle

Involvement of CYP2E1 as A Low-Affinity Enzyme in Phenacetin O-Deethylation in Human Liver Microsomes

Kaoru Kobayashi, Miki Nakajima, Kanako Oshima, Noriaki Shimada, Tsuyoshi Yokoi and Kan Chiba
Drug Metabolism and Disposition August 1999, 27 (8) 860-865;

Article Information

vol. 27 no. 8 860-865
PubMed 
10421611
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 8, 1999
  • Accepted May 3, 1999
  • Published online August 1, 1999.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kaoru Kobayashi1,
  2. Miki Nakajima2,
  3. Kanako Oshima1,
  4. Noriaki Shimada3,
  5. Tsuyoshi Yokoi2 and
  6. Kan Chiba1
  1. 1Laboratory of Biochemical Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Chiba University, Chiba (K.K., K.O., K.C.); 2Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa (M.N., T.Y.); and 3Materials Technology Research Laboratories, Daiichi Pure Chemicals Co. Ltd., Ibaraki (N.S.), Japan
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    Research ArticleArticle

    Involvement of CYP2E1 as A Low-Affinity Enzyme in Phenacetin O-Deethylation in Human Liver Microsomes

    Kaoru Kobayashi, Miki Nakajima, Kanako Oshima, Noriaki Shimada, Tsuyoshi Yokoi and Kan Chiba
    Drug Metabolism and Disposition August 1, 1999, 27 (8) 860-865;
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