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Research ArticleArticle

Rapid Characterization of the Major Drug-Metabolizing Human Hepatic Cytochrome P-450 Enzymes Expressed in Escherichia coli

Dermot F. McGinnity, Sarah J. Griffin, Graeme C. Moody, Mike Voice, Stephen Hanlon, Thomas Friedberg and Robert J. Riley
Drug Metabolism and Disposition September 1999, 27 (9) 1017-1023;

Article Information

vol. 27 no. 9 1017-1023
PubMed 
10460801
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 17, 1999
  • Accepted June 15, 1999
  • Published online September 1, 1999.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Dermot F. McGinnity1,
  2. Sarah J. Griffin1,
  3. Graeme C. Moody1,
  4. Mike Voice2,
  5. Stephen Hanlon2,
  6. Thomas Friedberg2 and
  7. Robert J. Riley1
  1. 1Department of Physical & Metabolic Sciences, AstraZeneca R&D Charnwood, Loughborough, Leicestershire (D.F.M., S.J.G., G.C.M., R.J.R.); and 2Biomedical Research Centre, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom (M.V., S.H., T.F.)
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    Research ArticleArticle

    Rapid Characterization of the Major Drug-Metabolizing Human Hepatic Cytochrome P-450 Enzymes Expressed in Escherichia coli

    Dermot F. McGinnity, Sarah J. Griffin, Graeme C. Moody, Mike Voice, Stephen Hanlon, Thomas Friedberg and Robert J. Riley
    Drug Metabolism and Disposition September 1, 1999, 27 (9) 1017-1023;
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