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Index by author

October 01, 2000; Volume 28,Issue 10

A

  1. Achira, Meguru

    1. Selective Inhibition of Human Cytochrome P450 3A4 byN-[2(R)-Hydroxy-1(S)-indanyl]-5-[2(S)-(1,1-dimethylethylaminocarbonyl)-4-[(furo[2,3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethylpentanamide and P-glycoprotein by Valspodar in Gene Transfectant Systems
      Iichiro Kawahara, Yukio Kato, Hiroshi Suzuki, Meguru Achira, Kiyomi Ito, Charles L. Crespi and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2000, 28 (10) 1238-1243;

  2. Ammon, Susanne

    1. In Vitro Interaction of Codeine and Diclofenac
      Susanne Ammon, Oliver von Richter, Ute Hofmann, Klaus-Peter Thon, Michel Eichelbaum and Gerd Mikus
      Drug Metabolism and Disposition October 2000, 28 (10) 1149-1152;

  3. Angus, Peter W.

    1. Impaired Elimination of Propranolol Due to Right Heart Failure: Drug Clearance in the Isolated Liver and Its Relationship to Intrinsic Metabolic Capacity
      Connie Y. Ng, Hany Ghabrial, Denis J. Morgan, Michael S. Ching, Richard A. Smallwood and Peter W. Angus
      Drug Metabolism and Disposition October 2000, 28 (10) 1217-1221;

B

  1. Barone, Gary W.

    1. Glucuronidation of Estrogens and Retinoic Acid and Expression of UDP-Glucuronosyltransferase 2B7 in Human Intestinal Mucosa
      Piotr J. Czernik, Joanna M. Little, Gary W. Barone, Jean-Pierre Raufman and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2000, 28 (10) 1210-1216;

  2. Barton, Paula T.

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

  3. Boobis, Alan R.

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

  4. Brouwer, Eric

    1. Measurement of Fraction Unbound Paclitaxel in Human Plasma
      Eric Brouwer, Jaap Verweij, Peter De Bruijn, Walter J. Loos, Marrimuthoo Pillay, Dirk Buijs and Alex Sparreboom
      Drug Metabolism and Disposition October 2000, 28 (10) 1141-1145;

  5. Buijs, Dirk

    1. Measurement of Fraction Unbound Paclitaxel in Human Plasma
      Eric Brouwer, Jaap Verweij, Peter De Bruijn, Walter J. Loos, Marrimuthoo Pillay, Dirk Buijs and Alex Sparreboom
      Drug Metabolism and Disposition October 2000, 28 (10) 1141-1145;

C

  1. Ching, Michael S.

    1. Impaired Elimination of Propranolol Due to Right Heart Failure: Drug Clearance in the Isolated Liver and Its Relationship to Intrinsic Metabolic Capacity
      Connie Y. Ng, Hany Ghabrial, Denis J. Morgan, Michael S. Ching, Richard A. Smallwood and Peter W. Angus
      Drug Metabolism and Disposition October 2000, 28 (10) 1217-1221;

  2. Collier, Abby C.

    1. A Highly Sensitive Fluorescent Microplate Method for the Determination of UDP-Glucuronosyl Transferase Activity in Tissues and Placental Cell Lines
      Abby C. Collier, Malcolm D. Tingle, Jeffrey A. Keelan, James W. Paxton and Murray D. Mitchell
      Drug Metabolism and Disposition October 2000, 28 (10) 1184-1186;

  3. Court, Michael H.

    1. CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
      Leah M. Hesse, Karthik Venkatakrishnan, Michael H. Court, Lisa L. von Moltke, Su X. Duan, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1176-1183;

  4. Crespi, Charles L.

    1. Selective Inhibition of Human Cytochrome P450 3A4 byN-[2(R)-Hydroxy-1(S)-indanyl]-5-[2(S)-(1,1-dimethylethylaminocarbonyl)-4-[(furo[2,3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethylpentanamide and P-glycoprotein by Valspodar in Gene Transfectant Systems
      Iichiro Kawahara, Yukio Kato, Hiroshi Suzuki, Meguru Achira, Kiyomi Ito, Charles L. Crespi and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2000, 28 (10) 1238-1243;

  5. Czernik, Piotr J.

    1. Glucuronidation of Estrogens and Retinoic Acid and Expression of UDP-Glucuronosyltransferase 2B7 in Human Intestinal Mucosa
      Piotr J. Czernik, Joanna M. Little, Gary W. Barone, Jean-Pierre Raufman and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2000, 28 (10) 1210-1216;

D

  1. Dean, Dennis C.

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;

  2. De Bruijn, Peter

    1. Measurement of Fraction Unbound Paclitaxel in Human Plasma
      Eric Brouwer, Jaap Verweij, Peter De Bruijn, Walter J. Loos, Marrimuthoo Pillay, Dirk Buijs and Alex Sparreboom
      Drug Metabolism and Disposition October 2000, 28 (10) 1141-1145;

  3. Doss, George

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;

  4. Douya, Rika

    1. The Involvement of Flavin-Containing Monooxygenase but Not CYP3A4 in Metabolism of Itopride Hydrochloride, a Gastroprokinetic Agent: Comparison with Cisapride and Mosapride Citrate
      Taisei Mushiroda, Rika Douya, Eiji Takahara and Osamu Nagata
      Drug Metabolism and Disposition October 2000, 28 (10) 1231-1237;

  5. Duan, Su X.

    1. CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
      Leah M. Hesse, Karthik Venkatakrishnan, Michael H. Court, Lisa L. von Moltke, Su X. Duan, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1176-1183;

  6. Dvorchik, Barry H.

    1. Disposition and Toxicity of a Mixed Backbone Antisense Oligonucleotide, Targeted against Human Cytomegalovirus, after Intravitreal Injection of Escalating Single Doses in the Rabbit
      Barry H. Dvorchik and Judith K. Marquis
      Drug Metabolism and Disposition October 2000, 28 (10) 1255-1261;

E

  1. Edwards, Robert J.

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

  2. Eichelbaum, Michel

    1. In Vitro Interaction of Codeine and Diclofenac
      Susanne Ammon, Oliver von Richter, Ute Hofmann, Klaus-Peter Thon, Michel Eichelbaum and Gerd Mikus
      Drug Metabolism and Disposition October 2000, 28 (10) 1149-1152;

  3. Ekins, Sean

    1. (R)-, (S)-, and Racemic Fluoxetine N-Demethylation by Human Cytochrome P450 Enzymes
      Jeannine M. Margolis, John P. O'Donnell, Dayna C. Mankowski, Sean Ekins and R. Scott Obach
      Drug Metabolism and Disposition October 2000, 28 (10) 1187-1191;

F

  1. Faucette, Stephanie R.

    1. Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity
      Stephanie R. Faucette, Roy L. Hawke, Edward L. Lecluyse, Stacy S. Shord, Bingfang Yan, Ronald M. Laethem and Celeste M. Lindley
      Drug Metabolism and Disposition October 2000, 28 (10) 1222-1230;

G

  1. Galchev, Vladimir

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

  2. Geer, Leslie A.

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;

  3. Ghabrial, Hany

    1. Impaired Elimination of Propranolol Due to Right Heart Failure: Drug Clearance in the Isolated Liver and Its Relationship to Intrinsic Metabolic Capacity
      Connie Y. Ng, Hany Ghabrial, Denis J. Morgan, Michael S. Ching, Richard A. Smallwood and Peter W. Angus
      Drug Metabolism and Disposition October 2000, 28 (10) 1217-1221;

  4. Greenblatt, David J.

    1. Metabolism of the Antidepressant Mirtazapine In Vitro: Contribution of Cytochromes P-450 1A2, 2D6, and 3A4
      Elke Störmer, Lisa L. von Moltke, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1168-1175;
    2. CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
      Leah M. Hesse, Karthik Venkatakrishnan, Michael H. Court, Lisa L. von Moltke, Su X. Duan, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1176-1183;

  5. Guyonnet, Isabelle

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

H

  1. Halpin, Rita A.

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;

  2. Hawke, Roy L.

    1. Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity
      Stephanie R. Faucette, Roy L. Hawke, Edward L. Lecluyse, Stacy S. Shord, Bingfang Yan, Ronald M. Laethem and Celeste M. Lindley
      Drug Metabolism and Disposition October 2000, 28 (10) 1222-1230;

  3. Hesse, Leah M.

    1. CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
      Leah M. Hesse, Karthik Venkatakrishnan, Michael H. Court, Lisa L. von Moltke, Su X. Duan, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1176-1183;

  4. Hofmann, Ute

    1. In Vitro Interaction of Codeine and Diclofenac
      Susanne Ammon, Oliver von Richter, Ute Hofmann, Klaus-Peter Thon, Michel Eichelbaum and Gerd Mikus
      Drug Metabolism and Disposition October 2000, 28 (10) 1149-1152;

  5. Hughes, Helen

    1. In Vivo Metabolism and Mass Balance of 4-[4-Fluorophenoxy]benzaldehyde Semicarbazone in Rats
      Kumar Ramu, Gilbert N. Lam and Helen Hughes
      Drug Metabolism and Disposition October 2000, 28 (10) 1153-1161;

I

  1. Igarashi, Takashi

    1. Both cMOAT/MRP2 and Another Unknown Transporter(s) Are Responsible for the Biliary Excretion of Glucuronide Conjugate of the Nonpeptide Angiotensin II Antagonist, Telmisaltan
      Yukio Kato, Takashi Igarashi, Yuichi Sugiyama and Akiko Nishino
      Drug Metabolism and Disposition October 2000, 28 (10) 1146-1148;

  2. Ikeda, Kazumasa

    1. Tissue Distribution and Biotransformation of Potassium Oxonate after Oral Administration of a Novel Antitumor Agent (Drug Combination of Tegafur, 5-Chloro-2,4-dihydroxypyridine, and Potassium Oxonate) to Rats
      Kunihiro Yoshisue, Hirotoshi Masuda, Eiji Matsushima, Kazumasa Ikeda, Sekio Nagayama and Yasuro Kawaguchi
      Drug Metabolism and Disposition October 2000, 28 (10) 1162-1167;

  3. Ito, Kiyomi

    1. Selective Inhibition of Human Cytochrome P450 3A4 byN-[2(R)-Hydroxy-1(S)-indanyl]-5-[2(S)-(1,1-dimethylethylaminocarbonyl)-4-[(furo[2,3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethylpentanamide and P-glycoprotein by Valspodar in Gene Transfectant Systems
      Iichiro Kawahara, Yukio Kato, Hiroshi Suzuki, Meguru Achira, Kiyomi Ito, Charles L. Crespi and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2000, 28 (10) 1238-1243;

J

  1. Jones, Allen N.

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;

K

  1. Kato, Yukio

    1. Both cMOAT/MRP2 and Another Unknown Transporter(s) Are Responsible for the Biliary Excretion of Glucuronide Conjugate of the Nonpeptide Angiotensin II Antagonist, Telmisaltan
      Yukio Kato, Takashi Igarashi, Yuichi Sugiyama and Akiko Nishino
      Drug Metabolism and Disposition October 2000, 28 (10) 1146-1148;
    2. Selective Inhibition of Human Cytochrome P450 3A4 byN-[2(R)-Hydroxy-1(S)-indanyl]-5-[2(S)-(1,1-dimethylethylaminocarbonyl)-4-[(furo[2,3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethylpentanamide and P-glycoprotein by Valspodar in Gene Transfectant Systems
      Iichiro Kawahara, Yukio Kato, Hiroshi Suzuki, Meguru Achira, Kiyomi Ito, Charles L. Crespi and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2000, 28 (10) 1238-1243;

  2. Kawaguchi, Yasuro

    1. Tissue Distribution and Biotransformation of Potassium Oxonate after Oral Administration of a Novel Antitumor Agent (Drug Combination of Tegafur, 5-Chloro-2,4-dihydroxypyridine, and Potassium Oxonate) to Rats
      Kunihiro Yoshisue, Hirotoshi Masuda, Eiji Matsushima, Kazumasa Ikeda, Sekio Nagayama and Yasuro Kawaguchi
      Drug Metabolism and Disposition October 2000, 28 (10) 1162-1167;

  3. Kawahara, Iichiro

    1. Selective Inhibition of Human Cytochrome P450 3A4 byN-[2(R)-Hydroxy-1(S)-indanyl]-5-[2(S)-(1,1-dimethylethylaminocarbonyl)-4-[(furo[2,3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethylpentanamide and P-glycoprotein by Valspodar in Gene Transfectant Systems
      Iichiro Kawahara, Yukio Kato, Hiroshi Suzuki, Meguru Achira, Kiyomi Ito, Charles L. Crespi and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2000, 28 (10) 1238-1243;

  4. Keelan, Jeffrey A.

    1. A Highly Sensitive Fluorescent Microplate Method for the Determination of UDP-Glucuronosyl Transferase Activity in Tissues and Placental Cell Lines
      Abby C. Collier, Malcolm D. Tingle, Jeffrey A. Keelan, James W. Paxton and Murray D. Mitchell
      Drug Metabolism and Disposition October 2000, 28 (10) 1184-1186;

  5. Kindt, Erick

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

  6. Kostrubsky, Vsevolod E.

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

L

  1. Laethem, Ronald M.

    1. Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity
      Stephanie R. Faucette, Roy L. Hawke, Edward L. Lecluyse, Stacy S. Shord, Bingfang Yan, Ronald M. Laethem and Celeste M. Lindley
      Drug Metabolism and Disposition October 2000, 28 (10) 1222-1230;

  2. Lake, Brian G.

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

  3. Lam, Gilbert N.

    1. In Vivo Metabolism and Mass Balance of 4-[4-Fluorophenoxy]benzaldehyde Semicarbazone in Rats
      Kumar Ramu, Gilbert N. Lam and Helen Hughes
      Drug Metabolism and Disposition October 2000, 28 (10) 1153-1161;

  4. Lecluyse, Edward L.

    1. Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity
      Stephanie R. Faucette, Roy L. Hawke, Edward L. Lecluyse, Stacy S. Shord, Bingfang Yan, Ronald M. Laethem and Celeste M. Lindley
      Drug Metabolism and Disposition October 2000, 28 (10) 1222-1230;

  5. Lindley, Celeste M.

    1. Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity
      Stephanie R. Faucette, Roy L. Hawke, Edward L. Lecluyse, Stacy S. Shord, Bingfang Yan, Ronald M. Laethem and Celeste M. Lindley
      Drug Metabolism and Disposition October 2000, 28 (10) 1222-1230;

  6. Little, Joanna M.

    1. Glucuronidation of Estrogens and Retinoic Acid and Expression of UDP-Glucuronosyltransferase 2B7 in Human Intestinal Mucosa
      Piotr J. Czernik, Joanna M. Little, Gary W. Barone, Jean-Pierre Raufman and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2000, 28 (10) 1210-1216;

  7. Loos, Walter J.

    1. Measurement of Fraction Unbound Paclitaxel in Human Plasma
      Eric Brouwer, Jaap Verweij, Peter De Bruijn, Walter J. Loos, Marrimuthoo Pillay, Dirk Buijs and Alex Sparreboom
      Drug Metabolism and Disposition October 2000, 28 (10) 1141-1145;

M

  1. Mankowski, Dayna C.

    1. (R)-, (S)-, and Racemic Fluoxetine N-Demethylation by Human Cytochrome P450 Enzymes
      Jeannine M. Margolis, John P. O'Donnell, Dayna C. Mankowski, Sean Ekins and R. Scott Obach
      Drug Metabolism and Disposition October 2000, 28 (10) 1187-1191;

  2. Margolis, Jeannine M.

    1. (R)-, (S)-, and Racemic Fluoxetine N-Demethylation by Human Cytochrome P450 Enzymes
      Jeannine M. Margolis, John P. O'Donnell, Dayna C. Mankowski, Sean Ekins and R. Scott Obach
      Drug Metabolism and Disposition October 2000, 28 (10) 1187-1191;

  3. Marks, Tina M.

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;

  4. Marquis, Judith K.

    1. Disposition and Toxicity of a Mixed Backbone Antisense Oligonucleotide, Targeted against Human Cytomegalovirus, after Intravitreal Injection of Escalating Single Doses in the Rabbit
      Barry H. Dvorchik and Judith K. Marquis
      Drug Metabolism and Disposition October 2000, 28 (10) 1255-1261;

  5. Masuda, Hirotoshi

    1. Tissue Distribution and Biotransformation of Potassium Oxonate after Oral Administration of a Novel Antitumor Agent (Drug Combination of Tegafur, 5-Chloro-2,4-dihydroxypyridine, and Potassium Oxonate) to Rats
      Kunihiro Yoshisue, Hirotoshi Masuda, Eiji Matsushima, Kazumasa Ikeda, Sekio Nagayama and Yasuro Kawaguchi
      Drug Metabolism and Disposition October 2000, 28 (10) 1162-1167;

  6. Matsushima, Eiji

    1. Tissue Distribution and Biotransformation of Potassium Oxonate after Oral Administration of a Novel Antitumor Agent (Drug Combination of Tegafur, 5-Chloro-2,4-dihydroxypyridine, and Potassium Oxonate) to Rats
      Kunihiro Yoshisue, Hirotoshi Masuda, Eiji Matsushima, Kazumasa Ikeda, Sekio Nagayama and Yasuro Kawaguchi
      Drug Metabolism and Disposition October 2000, 28 (10) 1162-1167;

  7. Melillo, David

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;

  8. Mikus, Gerd

    1. In Vitro Interaction of Codeine and Diclofenac
      Susanne Ammon, Oliver von Richter, Ute Hofmann, Klaus-Peter Thon, Michel Eichelbaum and Gerd Mikus
      Drug Metabolism and Disposition October 2000, 28 (10) 1149-1152;

  9. Mitchell, Murray D.

    1. A Highly Sensitive Fluorescent Microplate Method for the Determination of UDP-Glucuronosyl Transferase Activity in Tissues and Placental Cell Lines
      Abby C. Collier, Malcolm D. Tingle, Jeffrey A. Keelan, James W. Paxton and Murray D. Mitchell
      Drug Metabolism and Disposition October 2000, 28 (10) 1184-1186;

  10. Morgan, Denis J.

    1. Impaired Elimination of Propranolol Due to Right Heart Failure: Drug Clearance in the Isolated Liver and Its Relationship to Intrinsic Metabolic Capacity
      Connie Y. Ng, Hany Ghabrial, Denis J. Morgan, Michael S. Ching, Richard A. Smallwood and Peter W. Angus
      Drug Metabolism and Disposition October 2000, 28 (10) 1217-1221;

  11. Mushiroda, Taisei

    1. The Involvement of Flavin-Containing Monooxygenase but Not CYP3A4 in Metabolism of Itopride Hydrochloride, a Gastroprokinetic Agent: Comparison with Cisapride and Mosapride Citrate
      Taisei Mushiroda, Rika Douya, Eiji Takahara and Osamu Nagata
      Drug Metabolism and Disposition October 2000, 28 (10) 1231-1237;

N

  1. Nagata, Osamu

    1. The Involvement of Flavin-Containing Monooxygenase but Not CYP3A4 in Metabolism of Itopride Hydrochloride, a Gastroprokinetic Agent: Comparison with Cisapride and Mosapride Citrate
      Taisei Mushiroda, Rika Douya, Eiji Takahara and Osamu Nagata
      Drug Metabolism and Disposition October 2000, 28 (10) 1231-1237;

  2. Nagayama, Sekio

    1. Tissue Distribution and Biotransformation of Potassium Oxonate after Oral Administration of a Novel Antitumor Agent (Drug Combination of Tegafur, 5-Chloro-2,4-dihydroxypyridine, and Potassium Oxonate) to Rats
      Kunihiro Yoshisue, Hirotoshi Masuda, Eiji Matsushima, Kazumasa Ikeda, Sekio Nagayama and Yasuro Kawaguchi
      Drug Metabolism and Disposition October 2000, 28 (10) 1162-1167;

  3. Ng, Connie Y.

    1. Impaired Elimination of Propranolol Due to Right Heart Failure: Drug Clearance in the Isolated Liver and Its Relationship to Intrinsic Metabolic Capacity
      Connie Y. Ng, Hany Ghabrial, Denis J. Morgan, Michael S. Ching, Richard A. Smallwood and Peter W. Angus
      Drug Metabolism and Disposition October 2000, 28 (10) 1217-1221;

  4. Nishino, Akiko

    1. Both cMOAT/MRP2 and Another Unknown Transporter(s) Are Responsible for the Biliary Excretion of Glucuronide Conjugate of the Nonpeptide Angiotensin II Antagonist, Telmisaltan
      Yukio Kato, Takashi Igarashi, Yuichi Sugiyama and Akiko Nishino
      Drug Metabolism and Disposition October 2000, 28 (10) 1146-1148;

O

  1. O'Donnell, John P.

    1. (R)-, (S)-, and Racemic Fluoxetine N-Demethylation by Human Cytochrome P450 Enzymes
      Jeannine M. Margolis, John P. O'Donnell, Dayna C. Mankowski, Sean Ekins and R. Scott Obach
      Drug Metabolism and Disposition October 2000, 28 (10) 1187-1191;

  2. Obach, R. Scott

    1. (R)-, (S)-, and Racemic Fluoxetine N-Demethylation by Human Cytochrome P450 Enzymes
      Jeannine M. Margolis, John P. O'Donnell, Dayna C. Mankowski, Sean Ekins and R. Scott Obach
      Drug Metabolism and Disposition October 2000, 28 (10) 1187-1191;

P

  1. Paxton, James W.

    1. A Highly Sensitive Fluorescent Microplate Method for the Determination of UDP-Glucuronosyl Transferase Activity in Tissues and Placental Cell Lines
      Abby C. Collier, Malcolm D. Tingle, Jeffrey A. Keelan, James W. Paxton and Murray D. Mitchell
      Drug Metabolism and Disposition October 2000, 28 (10) 1184-1186;

  2. Pelkonen, Olavi

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

  3. Pillay, Marrimuthoo

    1. Measurement of Fraction Unbound Paclitaxel in Human Plasma
      Eric Brouwer, Jaap Verweij, Peter De Bruijn, Walter J. Loos, Marrimuthoo Pillay, Dirk Buijs and Alex Sparreboom
      Drug Metabolism and Disposition October 2000, 28 (10) 1141-1145;

  4. Price, Roger J.

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

R

  1. Radominska-Pandya, Anna

    1. Glucuronidation of Estrogens and Retinoic Acid and Expression of UDP-Glucuronosyltransferase 2B7 in Human Intestinal Mucosa
      Piotr J. Czernik, Joanna M. Little, Gary W. Barone, Jean-Pierre Raufman and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2000, 28 (10) 1210-1216;

  2. Ramachandran, Vinod

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

  3. Ramu, Kumar

    1. In Vivo Metabolism and Mass Balance of 4-[4-Fluorophenoxy]benzaldehyde Semicarbazone in Rats
      Kumar Ramu, Gilbert N. Lam and Helen Hughes
      Drug Metabolism and Disposition October 2000, 28 (10) 1153-1161;

  4. Raufman, Jean-Pierre

    1. Glucuronidation of Estrogens and Retinoic Acid and Expression of UDP-Glucuronosyltransferase 2B7 in Human Intestinal Mucosa
      Piotr J. Czernik, Joanna M. Little, Gary W. Barone, Jean-Pierre Raufman and Anna Radominska-Pandya
      Drug Metabolism and Disposition October 2000, 28 (10) 1210-1216;

  5. Renwick, Anthony B.

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

  6. Rose, Kelly

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

S

  1. Schrag, Michael L.

    1. Topological Alteration of the CYP3A4 Active Site by the Divalent Cation Mg2+
      Michael L. Schrag and Larry C. Wienkers
      Drug Metabolism and Disposition October 2000, 28 (10) 1198-1201;

  2. Shader, Richard I.

    1. Metabolism of the Antidepressant Mirtazapine In Vitro: Contribution of Cytochromes P-450 1A2, 2D6, and 3A4
      Elke Störmer, Lisa L. von Moltke, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1168-1175;
    2. CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
      Leah M. Hesse, Karthik Venkatakrishnan, Michael H. Court, Lisa L. von Moltke, Su X. Duan, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1176-1183;

  3. Shord, Stacy S.

    1. Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity
      Stephanie R. Faucette, Roy L. Hawke, Edward L. Lecluyse, Stacy S. Shord, Bingfang Yan, Ronald M. Laethem and Celeste M. Lindley
      Drug Metabolism and Disposition October 2000, 28 (10) 1222-1230;

  4. Sinclair, Jacqueline F.

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

  5. Sinz, Michael

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

  6. Smallwood, Richard A.

    1. Impaired Elimination of Propranolol Due to Right Heart Failure: Drug Clearance in the Isolated Liver and Its Relationship to Intrinsic Metabolic Capacity
      Connie Y. Ng, Hany Ghabrial, Denis J. Morgan, Michael S. Ching, Richard A. Smallwood and Peter W. Angus
      Drug Metabolism and Disposition October 2000, 28 (10) 1217-1221;

  7. Sparreboom, Alex

    1. Measurement of Fraction Unbound Paclitaxel in Human Plasma
      Eric Brouwer, Jaap Verweij, Peter De Bruijn, Walter J. Loos, Marrimuthoo Pillay, Dirk Buijs and Alex Sparreboom
      Drug Metabolism and Disposition October 2000, 28 (10) 1141-1145;

  8. Störmer, Elke

    1. Metabolism of the Antidepressant Mirtazapine In Vitro: Contribution of Cytochromes P-450 1A2, 2D6, and 3A4
      Elke Störmer, Lisa L. von Moltke, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1168-1175;

  9. Strom, Stephen C.

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

  10. Sugiyama, Yuichi

    1. Both cMOAT/MRP2 and Another Unknown Transporter(s) Are Responsible for the Biliary Excretion of Glucuronide Conjugate of the Nonpeptide Angiotensin II Antagonist, Telmisaltan
      Yukio Kato, Takashi Igarashi, Yuichi Sugiyama and Akiko Nishino
      Drug Metabolism and Disposition October 2000, 28 (10) 1146-1148;
    2. Selective Inhibition of Human Cytochrome P450 3A4 byN-[2(R)-Hydroxy-1(S)-indanyl]-5-[2(S)-(1,1-dimethylethylaminocarbonyl)-4-[(furo[2,3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethylpentanamide and P-glycoprotein by Valspodar in Gene Transfectant Systems
      Iichiro Kawahara, Yukio Kato, Hiroshi Suzuki, Meguru Achira, Kiyomi Ito, Charles L. Crespi and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2000, 28 (10) 1238-1243;

  11. Suzuki, Hiroshi

    1. Selective Inhibition of Human Cytochrome P450 3A4 byN-[2(R)-Hydroxy-1(S)-indanyl]-5-[2(S)-(1,1-dimethylethylaminocarbonyl)-4-[(furo[2,3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethylpentanamide and P-glycoprotein by Valspodar in Gene Transfectant Systems
      Iichiro Kawahara, Yukio Kato, Hiroshi Suzuki, Meguru Achira, Kiyomi Ito, Charles L. Crespi and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2000, 28 (10) 1238-1243;

T

  1. Takahara, Eiji

    1. The Involvement of Flavin-Containing Monooxygenase but Not CYP3A4 in Metabolism of Itopride Hydrochloride, a Gastroprokinetic Agent: Comparison with Cisapride and Mosapride Citrate
      Taisei Mushiroda, Rika Douya, Eiji Takahara and Osamu Nagata
      Drug Metabolism and Disposition October 2000, 28 (10) 1231-1237;

  2. Thon, Klaus-Peter

    1. In Vitro Interaction of Codeine and Diclofenac
      Susanne Ammon, Oliver von Richter, Ute Hofmann, Klaus-Peter Thon, Michel Eichelbaum and Gerd Mikus
      Drug Metabolism and Disposition October 2000, 28 (10) 1149-1152;

  3. Tingle, Malcolm D.

    1. A Highly Sensitive Fluorescent Microplate Method for the Determination of UDP-Glucuronosyl Transferase Activity in Tissues and Placental Cell Lines
      Abby C. Collier, Malcolm D. Tingle, Jeffrey A. Keelan, James W. Paxton and Murray D. Mitchell
      Drug Metabolism and Disposition October 2000, 28 (10) 1184-1186;

  4. Tredger, J. Michael

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

V

  1. Venkatakrishnan, Karthik

    1. CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
      Leah M. Hesse, Karthik Venkatakrishnan, Michael H. Court, Lisa L. von Moltke, Su X. Duan, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1176-1183;

  2. Venkataramanan, Raman

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

  3. Verweij, Jaap

    1. Measurement of Fraction Unbound Paclitaxel in Human Plasma
      Eric Brouwer, Jaap Verweij, Peter De Bruijn, Walter J. Loos, Marrimuthoo Pillay, Dirk Buijs and Alex Sparreboom
      Drug Metabolism and Disposition October 2000, 28 (10) 1141-1145;

  4. von Moltke, Lisa L.

    1. Metabolism of the Antidepressant Mirtazapine In Vitro: Contribution of Cytochromes P-450 1A2, 2D6, and 3A4
      Elke Störmer, Lisa L. von Moltke, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1168-1175;
    2. CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants
      Leah M. Hesse, Karthik Venkatakrishnan, Michael H. Court, Lisa L. von Moltke, Su X. Duan, Richard I. Shader and David J. Greenblatt
      Drug Metabolism and Disposition October 2000, 28 (10) 1176-1183;

  5. von Richter, Oliver

    1. In Vitro Interaction of Codeine and Diclofenac
      Susanne Ammon, Oliver von Richter, Ute Hofmann, Klaus-Peter Thon, Michel Eichelbaum and Gerd Mikus
      Drug Metabolism and Disposition October 2000, 28 (10) 1149-1152;

  6. Vyas, Kamlesh P.

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;

W

  1. Watts, Patricia S.

    1. Differential Maintenance of Cytochrome P450 Enzymes in Cultured Precision-Cut Human Liver Slices
      Anthony B. Renwick, Patricia S. Watts, Robert J. Edwards, Paula T. Barton, Isabelle Guyonnet, Roger J. Price, J. Michael Tredger, Olavi Pelkonen, Alan R. Boobis and Brian G. Lake
      Drug Metabolism and Disposition October 2000, 28 (10) 1202-1209;

  2. Wen, Yuan Hua

    1. The Role of Conjugation in Hepatotoxicity of Troglitazone in Human and Porcine Hepatocyte Cultures
      Vsevolod E. Kostrubsky, Jacqueline F. Sinclair, Vinod Ramachandran, Raman Venkataramanan, Yuan Hua Wen, Erick Kindt, Vladimir Galchev, Kelly Rose, Michael Sinz and Stephen C. Strom
      Drug Metabolism and Disposition October 2000, 28 (10) 1192-1197;

  3. Wienkers, Larry C.

    1. Topological Alteration of the CYP3A4 Active Site by the Divalent Cation Mg2+
      Michael L. Schrag and Larry C. Wienkers
      Drug Metabolism and Disposition October 2000, 28 (10) 1198-1201;

Y

  1. Yan, Bingfang

    1. Validation of Bupropion Hydroxylation as a Selective Marker of Human Cytochrome P450 2B6 Catalytic Activity
      Stephanie R. Faucette, Roy L. Hawke, Edward L. Lecluyse, Stacy S. Shord, Bingfang Yan, Ronald M. Laethem and Celeste M. Lindley
      Drug Metabolism and Disposition October 2000, 28 (10) 1222-1230;

  2. Yoshisue, Kunihiro

    1. Tissue Distribution and Biotransformation of Potassium Oxonate after Oral Administration of a Novel Antitumor Agent (Drug Combination of Tegafur, 5-Chloro-2,4-dihydroxypyridine, and Potassium Oxonate) to Rats
      Kunihiro Yoshisue, Hirotoshi Masuda, Eiji Matsushima, Kazumasa Ikeda, Sekio Nagayama and Yasuro Kawaguchi
      Drug Metabolism and Disposition October 2000, 28 (10) 1162-1167;

Z

  1. Zhang, Kanyin E.

    1. The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
      Rita A. Halpin, Leslie A. Geer, Kanyin E. Zhang, Tina M. Marks, Dennis C. Dean, Allen N. Jones, David Melillo, George Doss and Kamlesh P. Vyas
      Drug Metabolism and Disposition October 2000, 28 (10) 1244-1254;
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