Table of Contents

Articles

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  Heterologous Expression of Cyp2k1 and Identification of the Expressed Protein (bv-Cyp2k1) As Lauric Acid (ω-1)-Hydroxylase and Aflatoxin B1exo-Epoxidase

  Yea-Huey Yang, Cristobal L. Miranda, Marilyn C. Henderson, Jun-Lan Wang-Buhler and Donald R. Buhler

  Drug Metabolism and Disposition November 2000, 28 (11) 1279-1283;
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  Cytochrome P4502C9 Is the Principal Catalyst of Racemic Acenocoumarol Hydroxylation Reactions in Human Liver Microsomes

  Henk H. Thijssen, Jean-Pierre Flinois and Phillippe H. Beaune

  Drug Metabolism and Disposition November 2000, 28 (11) 1284-1290;
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  CYP3A4 Is a Major Isoform Responsible for Oxidation of 7-Hydroxy-Δ⁸-tetrahydrocannabinol to 7-Oxo-Δ⁸-tetrahydrocannabinol in Human Liver Microsomes

  Tamihide Matsunaga, Nobuyuki Kishi, Shinsuke Higuchi, Kazuhito Watanabe, Tohru Ohshima and Ikuo Yamamoto

  Drug Metabolism and Disposition November 2000, 28 (11) 1291-1296;
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  Prenylflavonoids from Hops Inhibit the Metabolic Activation of the Carcinogenic Heterocyclic Amine 2-Amino-3-methylimidazo[4,5-f]quinoline, Mediated by cDNA-Expressed Human CYP1A2

  Cristobal L. Miranda, Yea-Huey Yang, Marilyn C. Henderson, Jan F. Stevens, Gilberto Santana-Rios, Max L. Deinzer and Donald R. Buhler

  Drug Metabolism and Disposition November 2000, 28 (11) 1297-1302;
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  A Significant Role of Human Cytochrome P450 2C8 in Amiodarone N-Deethylation: An Approach to Predict the Contribution with Relative Activity Factor

  Katsuhiro Ohyama, Miki Nakajima, Sumika Nakamura, Noriaki Shimada, Hiroshi Yamazaki and Tsuyoshi Yokoi

  Drug Metabolism and Disposition November 2000, 28 (11) 1303-1310;
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  Induction of Mouse CYP2J by Pyrazole in the Eye, Kidney, Liver, Lung, Olfactory Mucosa, and Small Intestine, but Not in the Heart

  Qiang Xie, Qing-Yu Zhang, Yan Zhang, Ting Su, Jun Gu, Laurence S. Kaminsky and Xinxin Ding

  Drug Metabolism and Disposition November 2000, 28 (11) 1311-1316;
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  Decreased in Vivo Metabolism of Drugs in Chronic Renal Failure

  François A. Leblond, Lise Giroux, Jean-Pierre Villeneuve and Vincent Pichette

  Drug Metabolism and Disposition November 2000, 28 (11) 1317-1320;
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  CYP2A5/CYP2A6 Expression in Mouse and Human Hepatocytes Treated with Various in Vivo Inducers

  Marı́a Teresa Donato, Pirkko Viitala, Cristina Rodriguez-Antona, Aija Lindfors, Jose V. Castell, Hannu Raunio, Maria Jose Gómez-Lechón and Olavi Pelkonen

  Drug Metabolism and Disposition November 2000, 28 (11) 1321-1326;
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  Automated Definition of the Enzymology of Drug Oxidation by the Major Human Drug Metabolizing Cytochrome P450s

  Dermot F. McGinnity, Alison J. Parker, Matthew Soars and Robert J. Riley

  Drug Metabolism and Disposition November 2000, 28 (11) 1327-1334;
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  Human Serum Paraoxonase (pon1) Isozymes Q and R Hydrolyze Lactones and Cyclic Carbonate Esters

  S. Billecke, D. Draganov, R. Counsell, P. Stetson, C. Watson, C. Hsu and B. N. La Du

  Drug Metabolism and Disposition November 2000, 28 (11) 1335-1342;
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  In Vitro Evaluation of the Disposition of A Novel Cysteine Protease Inhibitor

  Wolfgang Jacobsen, Uwe Christians and Leslie Z. Benet

  Drug Metabolism and Disposition November 2000, 28 (11) 1343-1351;
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  O-Glucuronidation of the Lung Carcinogen 4-(methylnitrosamino)-1- (3-Pyridyl)-1-Butanol (nnal) by Human Udp-Glucuronosyltransferases 2b7 and 1a9

  Qing Ren, Sharon E. Murphy, Zhong Zheng and Philip Lazarus

  Drug Metabolism and Disposition November 2000, 28 (11) 1352-1360;
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  Formation of A Dihydroxy Metabolite of Phenytoin in Human Liver Microsomes/cytosol: Roles of Cytochromes P450 2c9, 2c19, and 3a4

  Tomoko Komatsu, Hiroshi Yamazaki, Satoru Asahi, Elizabeth M. J. Gillam, F. Peter Guengerich, Miki Nakajima and Tsuyoshi Yokoi

  Drug Metabolism and Disposition November 2000, 28 (11) 1361-1368;
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  Lactonization Is the Critical First Step in the Disposition of the 3-Hydroxy-3-Methylglutaryl-Coa Reductase Inhibitor Atorvastatin

  Wolfgang Jacobsen, Bernd Kuhn, Andrea Soldner, Gabriele Kirchner, Karl-Fr. Sewing, Peter A. Kollman, Leslie Z. Benet and Uwe Christians

  Drug Metabolism and Disposition November 2000, 28 (11) 1369-1378;
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  Early Biotransformations of Oxaliplatin after Its Intravenous Administration to Cancer Patients

  Pierre Allain, Oliver Heudi, Annie Cailleux, Anne Le Bouil, Francis Larra, Michele Boisdron-Celle and Erik Gamelin

  Drug Metabolism and Disposition November 2000, 28 (11) 1379-1384;
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  The Specificity of Glucuronidation of Entacapone and Tolcapone by Recombinant Human Udp-Glucuronosyltransferases

  Pia Lautala, Brian T. Ethell, Jyrki Taskinen and Brian Burchell

  Drug Metabolism and Disposition November 2000, 28 (11) 1385-1389;