Milk Thistle, a Herbal Supplement, Decreases the Activity of CYP3A4 and Uridine Diphosphoglucuronosyl Transferase in Human Hepatocyte Cultures

	Abstract	Full	Pdf
Oct 2000	45	59	49
Nov 2000	55	69	49
Dec 2000	13	13	19
Jan 2001	8	15	16
Feb 2001	4	36	7
Mar 2001	6	42	13
Apr 2001	4	35	15
May 2001	5	30	26
Jun 2001	21	42	19
Jul 2001	8	23	18
Aug 2001	15	25	10
Sep 2001	15	18	27
Oct 2001	12	40	15
Nov 2001	3	17	27
Dec 2001	2	15	17
Jan 2002	14	35	29
Feb 2002	5	40	25
Mar 2002	8	32	28
Apr 2002	2	26	18
May 2002	5	22	25
Jun 2002	13	18	18
Jul 2002	7	51	25
Aug 2002	20	26	17
Sep 2002	8	15	22
Oct 2002	7	43	43
Nov 2002	3	35	34
Dec 2002	3	41	42
Jan 2003	1	36	40
Feb 2003	12	32	32
Mar 2003	15	22	23
Apr 2003	6	16	28
May 2003	8	33	20
Jun 2003	2	26	33
Jul 2003	9	32	20
Aug 2003	11	51	25
Sep 2003	3	43	27
Oct 2003	3	55	29
Nov 2003	11	62	19
Dec 2003	10	56	14
Jan 2004	12	54	25
Feb 2004	11	65	23
Mar 2004	14	61	20
Apr 2004	20	78	24
May 2004	9	29	19
Jun 2004	25	36	21
Jul 2004	12	42	14
Aug 2004	25	57	25
Sep 2004	22	61	21
Oct 2004	18	103	30
Nov 2004	22	58	28
Dec 2004	21	68	22
Jan 2005	25	64	21
Feb 2005	24	77	27
Mar 2005	14	99	23
Apr 2005	16	69	38
May 2005	7	64	21
Jun 2005	12	59	19
Jul 2005	7	66	31
Aug 2005	17	60	27
Sep 2005	11	69	40
Oct 2005	13	41	16
Nov 2005	21	48	31
Dec 2005	11	24	15
Jan 2006	8	80	17
Feb 2006	9	41	11
Mar 2006	22	44	17
Apr 2006	36	61	22
May 2006	67	65	21
Jun 2006	47	43	12
Jul 2006	40	42	27
Aug 2006	32	36	24
Sep 2006	49	40	26
Oct 2006	50	58	28
Nov 2006	62	70	29
Dec 2006	41	59	24
Jan 2007	44	66	27
Feb 2007	58	62	25
Mar 2007	52	96	27
Apr 2007	45	45	19
May 2007	35	48	18
Jun 2007	24	68	19
Jul 2007	33	66	17
Aug 2007	24	58	16
Sep 2007	29	56	18
Oct 2007	37	69	23
Nov 2007	38	67	33
Dec 2007	19	45	18
Jan 2008	9	44	23
Feb 2008	18	54	24
Mar 2008	17	55	21
Apr 2008	11	69	28
May 2008	15	44	14
Jun 2008	28	51	22
Jul 2008	19	61	11
Aug 2008	35	70	13
Sep 2008	44	45	20
Oct 2008	36	67	34
Nov 2008	43	58	24
Dec 2008	24	49	16
Jan 2009	37	57	18
Feb 2009	43	53	26
Mar 2009	49	73	20
Apr 2009	34	60	23
May 2009	29	50	27
Jun 2009	37	51	12
Jul 2009	19	55	13
Aug 2009	32	39	19
Sep 2009	37	40	18
Oct 2009	41	44	17
Nov 2009	33	36	8
Dec 2009	25	38	10
Jan 2010	45	108	26
Feb 2010	57	82	21
Mar 2010	37	92	31
Apr 2010	14	89	16
May 2010	26	128	17
Jun 2010	34	111	20
Jul 2010	31	99	16
Aug 2010	10	115	7
Sep 2010	11	133	27
Oct 2010	95	82	35
Nov 2010	42	80	30
Dec 2010	55	58	13
Jan 2011	45	68	8
Feb 2011	53	57	18
Mar 2011	47	75	34
Apr 2011	44	38	17
May 2011	54	57	26
Jun 2011	43	56	33
Jul 2011	56	40	17
Aug 2011	43	45	18
Sep 2011	44	55	32
Oct 2011	76	75	32
Nov 2011	70	77	24
Dec 2011	31	71	11
Jan 2012	31	50	15
Feb 2012	36	63	27
Mar 2012	37	50	22
Apr 2012	42	58	30
May 2012	44	45	38
Jun 2012	34	50	23
Jul 2012	40	59	23
Aug 2012	34	49	25
Sep 2012	31	40	18
Oct 2012	55	45	42
Nov 2012	46	45	35
Dec 2012	31	35	19
Jan 2013	54	76	34
Feb 2013	56	44	21
Mar 2013	48	63	37
Apr 2013	57	82	50
May 2013	56	51	19
Jun 2013	17	33	17
Jul 2013	26	20	10
Aug 2013	30	35	23
Sep 2013	51	25	19
Oct 2013	51	37	25
Nov 2013	42	32	14
Dec 2013	36	27	25
Jan 2014	34	38	18
Feb 2014	15	33	12
Mar 2014	23	37	15
Apr 2014	28	39	15
May 2014	24	33	28
Jun 2014	34	39	15
Jul 2014	22	41	32
Aug 2014	18	35	17
Sep 2014	32	35	15
Oct 2014	38	25	15
Nov 2014	32	26	13
Dec 2014	50	30	24
Jan 2015	36	30	11
Feb 2015	40	28	15
Mar 2015	48	34	18
Apr 2015	42	107	22
May 2015	34	151	20
Jun 2015	27	127	14
Jul 2015	43	112	16
Aug 2015	31	37	9
Sep 2015	35	55	8
Oct 2015	28	31	13
Nov 2015	138	29	10
Dec 2015	31	35	6
Jan 2016	32	38	11
Feb 2016	19	51	14
Mar 2016	14	33	18
Apr 2016	33	49	19
May 2016	50	52	23
Jun 2016	17	32	7
Jul 2016	18	36	13
Aug 2016	16	28	7
Sep 2016	24	77	8
Oct 2016	26	58	12
Nov 2016	28	33	12
Dec 2016	21	63	22
Jan 2017	10	57	8
Feb 2017	17	42	6
Mar 2017	21	81	6
Apr 2017	22	43	12
May 2017	26	74	13
Jun 2017	30	50	11
Jul 2017	17	36	9
Aug 2017	15	74	9
Sep 2017	27	65	5
Oct 2017	32	89	12
Nov 2017	26	85	11
Dec 2017	19	56	6
Jan 2018	49	60	8
Feb 2018	29	61	11
Mar 2018	35	62	9
Apr 2018	53	63	15
May 2018	31	75	15
Jun 2018	29	49	5
Jul 2018	36	47	11
Aug 2018	28	52	13
Sep 2018	32	41	12
Oct 2018	41	66	28
Nov 2018	44	55	23
Dec 2018	106	12	13
Jan 2019	83	4	4
Feb 2019	61	3	4
Mar 2019	52	5	6
Apr 2019	75	5	1
May 2019	73	2	4
Jun 2019	91	0	0
Jul 2019	93	2	0
Aug 2019	93	2	1
Sep 2019	47	4	1
Oct 2019	60	0	1
Nov 2019	90	3	1
Dec 2019	60	3	0
Jan 2020	73	2	0
Feb 2020	83	2	1
Mar 2020	94	4	3
Apr 2020	105	4	1
May 2020	76	0	0
Jun 2020	74	2	0
Jul 2020	58	0	0
Aug 2020	40	0	1
Sep 2020	34	5	0
Oct 2020	103	4	0
Nov 2020	81	2	1
Dec 2020	80	2	3
Jan 2021	86	12	2
Feb 2021	109	6	0