Index by author
December 01, 2000; Volume 28,Issue 12
A
Agouridas, Constantin
- You have accessEffects of Macrolide Antibiotics on CYP3A Expression in Human and Rat Hepatocytes: Interspecies Differences in Response to TroleandomycinNathalie Ledirac, Georges de Sousa, Franck Fontaine, Constantin Agouridas, Jean Gugenheim, Giocando Lorenzon and Roger RahmaniDrug Metabolism and Disposition December 2000, 28 (12) 1391-1393;
Aisaka, Kazuo
- You have accessDisposition and α1-Adrenoceptor Binding Characteristics of JTH-601 and Its Metabolites in Rat TissuesShizuo Yamada, Takashi Okura, Ryohei Kimura, Yoshiharu Deguchi, Yasunori Suzuki, Takuo Kobayashi and Kazuo AisakaDrug Metabolism and Disposition December 2000, 28 (12) 1487-1492;
Annaert, Pieter
- You have accessIncreased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal MetabolismJan Van Gelder, Sven Deferme, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget and Parick AugustijnsDrug Metabolism and Disposition December 2000, 28 (12) 1394-1396;
Antonian, Lida
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Augustijns, Parick
- You have accessIncreased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal MetabolismJan Van Gelder, Sven Deferme, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget and Parick AugustijnsDrug Metabolism and Disposition December 2000, 28 (12) 1394-1396;
B
Berger, Yves
- You have accessVery Slow Chiral Inversion of Clopidogrel in Rats: A Pharmacokinetic and Mechanistic InvestigationMarianne Reist, Marieke Roy-de Vos, Jean-Pierre Montseny, Joachim M. Mayer, Pierre-Alain Carrupt, Yves Berger and Bernard TestaDrug Metabolism and Disposition December 2000, 28 (12) 1405-1410;
Blanchard, Andrew P.
- You have accessSubstrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric SubstratesDavid M. Stresser, Andrew P. Blanchard, Stephanie D. Turner, John C. L. Erve, Andre A. Dandeneau, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition December 2000, 28 (12) 1440-1448;
Brouwer, Kim L. R.
- You have accessProbenecid-Associated Alterations in Valproic Acid Pharmacokinetics in Rats: Can in Vivo Disposition of Valproate Glucuronide Be Predicted from in Vitro Formation Data?E. Stacy Ward, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition December 2000, 28 (12) 1433-1439;
Bury, Michele
- You have accessComparative Tolerability, Pharmacodynamics, and Pharmacokinetics of a Metabolite of a Quinolizinone Hypnotic and Zolpidem in Healthy SubjectsJasper Dingemanse, Michele Bury, Yasmin Hussain and Paul van GiersbergenDrug Metabolism and Disposition December 2000, 28 (12) 1411-1416;
C
Carrupt, Pierre-Alain
- You have accessVery Slow Chiral Inversion of Clopidogrel in Rats: A Pharmacokinetic and Mechanistic InvestigationMarianne Reist, Marieke Roy-de Vos, Jean-Pierre Montseny, Joachim M. Mayer, Pierre-Alain Carrupt, Yves Berger and Bernard TestaDrug Metabolism and Disposition December 2000, 28 (12) 1405-1410;
Commandeur, Jan N. M.
- You have accessInfluence of N-Substitution of 7-Methoxy-4-(aminomethyl)-coumarin on Cytochrome P450 Metabolism and SelectivityJennifer Venhorst, Rob C. A. Onderwater, John H. N. Meerman, Jan N. M. Commandeur and Nico P. E. VermeulenDrug Metabolism and Disposition December 2000, 28 (12) 1524-1532;
Court, Michael H.
- You have accessComparison between Cytochrome P450 (CYP) Content and Relative Activity Approaches to Scaling from cDNA-Expressed CYPs to Human Liver Microsomes: Ratios of Accessory Proteins as Sources of Discrepancies between the ApproachesKarthik Venkatakrishnan, Lisa L. von Moltke, Michael H. Court, Jerold S. Harmatz, Charles L. Crespi and David J. GreenblattDrug Metabolism and Disposition December 2000, 28 (12) 1493-1504;
Crespi, Charles L.
- You have accessSubstrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric SubstratesDavid M. Stresser, Andrew P. Blanchard, Stephanie D. Turner, John C. L. Erve, Andre A. Dandeneau, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition December 2000, 28 (12) 1440-1448;
- You have accessComparison between Cytochrome P450 (CYP) Content and Relative Activity Approaches to Scaling from cDNA-Expressed CYPs to Human Liver Microsomes: Ratios of Accessory Proteins as Sources of Discrepancies between the ApproachesKarthik Venkatakrishnan, Lisa L. von Moltke, Michael H. Court, Jerold S. Harmatz, Charles L. Crespi and David J. GreenblattDrug Metabolism and Disposition December 2000, 28 (12) 1493-1504;
Cui, Yan-Yan
- You have accessCharacterization of Rat Liver Microsomal Metabolites of Clivorine, an Hepatotoxic Otonecine-Type Pyrrolizidine AlkaloidGe Lin, Yan-Yan Cui and Edward M. HawesDrug Metabolism and Disposition December 2000, 28 (12) 1475-1483;
D
Dandeneau, Andre A.
- You have accessSubstrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric SubstratesDavid M. Stresser, Andrew P. Blanchard, Stephanie D. Turner, John C. L. Erve, Andre A. Dandeneau, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition December 2000, 28 (12) 1440-1448;
De Clercq, Erik
- You have accessIncreased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal MetabolismJan Van Gelder, Sven Deferme, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget and Parick AugustijnsDrug Metabolism and Disposition December 2000, 28 (12) 1394-1396;
Deferme, Sven
- You have accessIncreased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal MetabolismJan Van Gelder, Sven Deferme, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget and Parick AugustijnsDrug Metabolism and Disposition December 2000, 28 (12) 1394-1396;
Deguchi, Yoshiharu
- You have accessDisposition and α1-Adrenoceptor Binding Characteristics of JTH-601 and Its Metabolites in Rat TissuesShizuo Yamada, Takashi Okura, Ryohei Kimura, Yoshiharu Deguchi, Yasunori Suzuki, Takuo Kobayashi and Kazuo AisakaDrug Metabolism and Disposition December 2000, 28 (12) 1487-1492;
de Sousa, Georges
- You have accessEffects of Macrolide Antibiotics on CYP3A Expression in Human and Rat Hepatocytes: Interspecies Differences in Response to TroleandomycinNathalie Ledirac, Georges de Sousa, Franck Fontaine, Constantin Agouridas, Jean Gugenheim, Giocando Lorenzon and Roger RahmaniDrug Metabolism and Disposition December 2000, 28 (12) 1391-1393;
Dingemanse, Jasper
- You have accessComparative Tolerability, Pharmacodynamics, and Pharmacokinetics of a Metabolite of a Quinolizinone Hypnotic and Zolpidem in Healthy SubjectsJasper Dingemanse, Michele Bury, Yasmin Hussain and Paul van GiersbergenDrug Metabolism and Disposition December 2000, 28 (12) 1411-1416;
Dong, Haijun
- You have accessInvolvement of Human Cytochrome P450 2D6 in the Bioactivation of AcetaminophenHaijun Dong, Robert L. Haining, Kenneth E. Thummel, Allan E. Rettie and Sidney D. NelsonDrug Metabolism and Disposition December 2000, 28 (12) 1397-1400;
E
Erve, John C. L.
- You have accessSubstrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric SubstratesDavid M. Stresser, Andrew P. Blanchard, Stephanie D. Turner, John C. L. Erve, Andre A. Dandeneau, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition December 2000, 28 (12) 1440-1448;
Evans, Allan M.
- You have accessDisposition of l-Carnitine and Its Short-Chain Esters, Acetyl-l-carnitine and Propionyl-l-carnitine, in the Rat Isolated Perfused LiverAngelo Mancinelli, Antonio Longo, Roger L. Nation and Allan M. EvansDrug Metabolism and Disposition December 2000, 28 (12) 1401-1404;
F
Fontaine, Franck
- You have accessEffects of Macrolide Antibiotics on CYP3A Expression in Human and Rat Hepatocytes: Interspecies Differences in Response to TroleandomycinNathalie Ledirac, Georges de Sousa, Franck Fontaine, Constantin Agouridas, Jean Gugenheim, Giocando Lorenzon and Roger RahmaniDrug Metabolism and Disposition December 2000, 28 (12) 1391-1393;
G
Goodfellow, Geoffrey H.
- You have accessPharmacogenetics of the ArylamineN-Acetyltransferases: A Symposium in Honor of Wendell W. WeberDavid W. Hein, Charlene A. McQueen, Denis M. Grant, Geoffrey H. Goodfellow, Fred F. Kadlubar and Wendell W. WeberDrug Metabolism and Disposition December 2000, 28 (12) 1425-1432;
Grant, Denis M.
- You have accessPharmacogenetics of the ArylamineN-Acetyltransferases: A Symposium in Honor of Wendell W. WeberDavid W. Hein, Charlene A. McQueen, Denis M. Grant, Geoffrey H. Goodfellow, Fred F. Kadlubar and Wendell W. WeberDrug Metabolism and Disposition December 2000, 28 (12) 1425-1432;
Greenblatt, David J.
- You have accessComparison between Cytochrome P450 (CYP) Content and Relative Activity Approaches to Scaling from cDNA-Expressed CYPs to Human Liver Microsomes: Ratios of Accessory Proteins as Sources of Discrepancies between the ApproachesKarthik Venkatakrishnan, Lisa L. von Moltke, Michael H. Court, Jerold S. Harmatz, Charles L. Crespi and David J. GreenblattDrug Metabolism and Disposition December 2000, 28 (12) 1493-1504;
Gugenheim, Jean
- You have accessEffects of Macrolide Antibiotics on CYP3A Expression in Human and Rat Hepatocytes: Interspecies Differences in Response to TroleandomycinNathalie Ledirac, Georges de Sousa, Franck Fontaine, Constantin Agouridas, Jean Gugenheim, Giocando Lorenzon and Roger RahmaniDrug Metabolism and Disposition December 2000, 28 (12) 1391-1393;
H
Haining, Robert L.
- You have accessInvolvement of Human Cytochrome P450 2D6 in the Bioactivation of AcetaminophenHaijun Dong, Robert L. Haining, Kenneth E. Thummel, Allan E. Rettie and Sidney D. NelsonDrug Metabolism and Disposition December 2000, 28 (12) 1397-1400;
Halada, Petr
- You have accessChemoenzymatic Preparation of Silybin β-Glucuronides and Their Biological EvaluationVladimír Kr̆en, Jitka Ulrichová, Pavel Kosina, David Stevenson, Petr Sedmera, Věra Přikrylová, Petr Halada and Vilím šsimánekDrug Metabolism and Disposition December 2000, 28 (12) 1513-1517;
Harmatz, Jerold S.
- You have accessComparison between Cytochrome P450 (CYP) Content and Relative Activity Approaches to Scaling from cDNA-Expressed CYPs to Human Liver Microsomes: Ratios of Accessory Proteins as Sources of Discrepancies between the ApproachesKarthik Venkatakrishnan, Lisa L. von Moltke, Michael H. Court, Jerold S. Harmatz, Charles L. Crespi and David J. GreenblattDrug Metabolism and Disposition December 2000, 28 (12) 1493-1504;
Hawes, Edward M.
- You have accessCharacterization of Rat Liver Microsomal Metabolites of Clivorine, an Hepatotoxic Otonecine-Type Pyrrolizidine AlkaloidGe Lin, Yan-Yan Cui and Edward M. HawesDrug Metabolism and Disposition December 2000, 28 (12) 1475-1483;
Hein, David W.
- You have accessPharmacogenetics of the ArylamineN-Acetyltransferases: A Symposium in Honor of Wendell W. WeberDavid W. Hein, Charlene A. McQueen, Denis M. Grant, Geoffrey H. Goodfellow, Fred F. Kadlubar and Wendell W. WeberDrug Metabolism and Disposition December 2000, 28 (12) 1425-1432;
Hirao, Yukihiro
- You have accessIn Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, a Novel Antimicrobial Agent, in Dog Liver MicrosomesKen Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Tadaaki Ohtani, Minoru Uchida and Gohachiro MiyamotoDrug Metabolism and Disposition December 2000, 28 (12) 1417-1424;
Hubbard, Deanna L.
- You have accessThe Incorporation of Cocaine and Metabolites into Hair: Effects of Dose and Hair PigmentationDeanna L. Hubbard, Diana G. Wilkins and Douglas E. RollinsDrug Metabolism and Disposition December 2000, 28 (12) 1464-1469;
Hussain, Yasmin
- You have accessComparative Tolerability, Pharmacodynamics, and Pharmacokinetics of a Metabolite of a Quinolizinone Hypnotic and Zolpidem in Healthy SubjectsJasper Dingemanse, Michele Bury, Yasmin Hussain and Paul van GiersbergenDrug Metabolism and Disposition December 2000, 28 (12) 1411-1416;
I
Imura-Miyoshi, Kaoru
- You have accessPanipenum, A Carbapenem Antibiotic, Increases the Level of Hepatic Udp-Glucuronic Acid in RatsNaotoshi Yamamura, Kaoru Imura-Miyoshi and Hideo NaganumaDrug Metabolism and Disposition December 2000, 28 (12) 1484-1486;
Ishii, Yasuyuki
- You have accessA Convenient In Vitro Screening Method for Predicting In Vivo Drug Metabolic Clearance Using Isolated Hepatocytes Suspended in SerumYoshihiro Shibata, Hiroyuki Takahashi and Yasuyuki IshiiDrug Metabolism and Disposition December 2000, 28 (12) 1518-1523;
K
Kadlubar, Fred F.
- You have accessPharmacogenetics of the ArylamineN-Acetyltransferases: A Symposium in Honor of Wendell W. WeberDavid W. Hein, Charlene A. McQueen, Denis M. Grant, Geoffrey H. Goodfellow, Fred F. Kadlubar and Wendell W. WeberDrug Metabolism and Disposition December 2000, 28 (12) 1425-1432;
Kestell, Philip
- You have accessIdentification of the Human Liver Cytochrome P450 Isoenzyme Responsible for the 6-Methylhydroxylation of the Novel Anticancer Drug 5,6-Dimethylxanthenone-4-acetic AcidShufeng Zhou, James W. Paxton, Malcolm D. Tingle and Philip KestellDrug Metabolism and Disposition December 2000, 28 (12) 1449-1456;
Kimura, Ryohei
- You have accessDisposition and α1-Adrenoceptor Binding Characteristics of JTH-601 and Its Metabolites in Rat TissuesShizuo Yamada, Takashi Okura, Ryohei Kimura, Yoshiharu Deguchi, Yasunori Suzuki, Takuo Kobayashi and Kazuo AisakaDrug Metabolism and Disposition December 2000, 28 (12) 1487-1492;
Kinget, Renaat
- You have accessIncreased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal MetabolismJan Van Gelder, Sven Deferme, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget and Parick AugustijnsDrug Metabolism and Disposition December 2000, 28 (12) 1394-1396;
Kobayashi, Takuo
- You have accessDisposition and α1-Adrenoceptor Binding Characteristics of JTH-601 and Its Metabolites in Rat TissuesShizuo Yamada, Takashi Okura, Ryohei Kimura, Yoshiharu Deguchi, Yasunori Suzuki, Takuo Kobayashi and Kazuo AisakaDrug Metabolism and Disposition December 2000, 28 (12) 1487-1492;
Komatsu, Tomoko
- You have accessRoles of Cytochromes P450 1A2, 2A6, and 2C8 in 5-Fluorouracil Formation from Tegafur, an Anticancer Prodrug, in Human Liver MicrosomesTomoko Komatsu, Hiroshi Yamazaki, Noriaki Shimada, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition December 2000, 28 (12) 1457-1463;
Kosina, Pavel
- You have accessChemoenzymatic Preparation of Silybin β-Glucuronides and Their Biological EvaluationVladimír Kr̆en, Jitka Ulrichová, Pavel Kosina, David Stevenson, Petr Sedmera, Věra Přikrylová, Petr Halada and Vilím šsimánekDrug Metabolism and Disposition December 2000, 28 (12) 1513-1517;
Kr̆en, Vladimír
- You have accessChemoenzymatic Preparation of Silybin β-Glucuronides and Their Biological EvaluationVladimír Kr̆en, Jitka Ulrichová, Pavel Kosina, David Stevenson, Petr Sedmera, Věra Přikrylová, Petr Halada and Vilím šsimánekDrug Metabolism and Disposition December 2000, 28 (12) 1513-1517;
Kudo, Shoji
- You have accessIn Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, a Novel Antimicrobial Agent, in Dog Liver MicrosomesKen Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Tadaaki Ohtani, Minoru Uchida and Gohachiro MiyamotoDrug Metabolism and Disposition December 2000, 28 (12) 1417-1424;
L
Ledirac, Nathalie
- You have accessEffects of Macrolide Antibiotics on CYP3A Expression in Human and Rat Hepatocytes: Interspecies Differences in Response to TroleandomycinNathalie Ledirac, Georges de Sousa, Franck Fontaine, Constantin Agouridas, Jean Gugenheim, Giocando Lorenzon and Roger RahmaniDrug Metabolism and Disposition December 2000, 28 (12) 1391-1393;
Lin, Ge
- You have accessCharacterization of Rat Liver Microsomal Metabolites of Clivorine, an Hepatotoxic Otonecine-Type Pyrrolizidine AlkaloidGe Lin, Yan-Yan Cui and Edward M. HawesDrug Metabolism and Disposition December 2000, 28 (12) 1475-1483;
Lindros, Kai O.
- You have accessEffect of Long-Term Ethanol Exposure on the Acinar Distribution of Hepatic Glutathione S-TransferaseTamara Vanhaecke, Kai O. Lindros, Teija Oinonen, Antoine Vercruysse and Vera RogiersDrug Metabolism and Disposition December 2000, 28 (12) 1470-1474;
Longo, Antonio
- You have accessDisposition of l-Carnitine and Its Short-Chain Esters, Acetyl-l-carnitine and Propionyl-l-carnitine, in the Rat Isolated Perfused LiverAngelo Mancinelli, Antonio Longo, Roger L. Nation and Allan M. EvansDrug Metabolism and Disposition December 2000, 28 (12) 1401-1404;
Lorenzon, Giocando
- You have accessEffects of Macrolide Antibiotics on CYP3A Expression in Human and Rat Hepatocytes: Interspecies Differences in Response to TroleandomycinNathalie Ledirac, Georges de Sousa, Franck Fontaine, Constantin Agouridas, Jean Gugenheim, Giocando Lorenzon and Roger RahmaniDrug Metabolism and Disposition December 2000, 28 (12) 1391-1393;
M
Madan, Ajay
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Mancinelli, Angelo
- You have accessDisposition of l-Carnitine and Its Short-Chain Esters, Acetyl-l-carnitine and Propionyl-l-carnitine, in the Rat Isolated Perfused LiverAngelo Mancinelli, Antonio Longo, Roger L. Nation and Allan M. EvansDrug Metabolism and Disposition December 2000, 28 (12) 1401-1404;
Mayer, Joachim M.
- You have accessVery Slow Chiral Inversion of Clopidogrel in Rats: A Pharmacokinetic and Mechanistic InvestigationMarianne Reist, Marieke Roy-de Vos, Jean-Pierre Montseny, Joachim M. Mayer, Pierre-Alain Carrupt, Yves Berger and Bernard TestaDrug Metabolism and Disposition December 2000, 28 (12) 1405-1410;
McQueen, Charlene A.
- You have accessPharmacogenetics of the ArylamineN-Acetyltransferases: A Symposium in Honor of Wendell W. WeberDavid W. Hein, Charlene A. McQueen, Denis M. Grant, Geoffrey H. Goodfellow, Fred F. Kadlubar and Wendell W. WeberDrug Metabolism and Disposition December 2000, 28 (12) 1425-1432;
Meerman, John H. N.
- You have accessInfluence of N-Substitution of 7-Methoxy-4-(aminomethyl)-coumarin on Cytochrome P450 Metabolism and SelectivityJennifer Venhorst, Rob C. A. Onderwater, John H. N. Meerman, Jan N. M. Commandeur and Nico P. E. VermeulenDrug Metabolism and Disposition December 2000, 28 (12) 1524-1532;
Miller, Vaughn P.
- You have accessSubstrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric SubstratesDavid M. Stresser, Andrew P. Blanchard, Stephanie D. Turner, John C. L. Erve, Andre A. Dandeneau, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition December 2000, 28 (12) 1440-1448;
Miyamoto, Gohachiro
- You have accessIn Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, a Novel Antimicrobial Agent, in Dog Liver MicrosomesKen Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Tadaaki Ohtani, Minoru Uchida and Gohachiro MiyamotoDrug Metabolism and Disposition December 2000, 28 (12) 1417-1424;
Montseny, Jean-Pierre
- You have accessVery Slow Chiral Inversion of Clopidogrel in Rats: A Pharmacokinetic and Mechanistic InvestigationMarianne Reist, Marieke Roy-de Vos, Jean-Pierre Montseny, Joachim M. Mayer, Pierre-Alain Carrupt, Yves Berger and Bernard TestaDrug Metabolism and Disposition December 2000, 28 (12) 1405-1410;
Morita, Seiji
- You have accessIn Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, a Novel Antimicrobial Agent, in Dog Liver MicrosomesKen Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Tadaaki Ohtani, Minoru Uchida and Gohachiro MiyamotoDrug Metabolism and Disposition December 2000, 28 (12) 1417-1424;
N
Naesens, Lieve
- You have accessIncreased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal MetabolismJan Van Gelder, Sven Deferme, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget and Parick AugustijnsDrug Metabolism and Disposition December 2000, 28 (12) 1394-1396;
Naganuma, Hideo
- You have accessPanipenum, A Carbapenem Antibiotic, Increases the Level of Hepatic Udp-Glucuronic Acid in RatsNaotoshi Yamamura, Kaoru Imura-Miyoshi and Hideo NaganumaDrug Metabolism and Disposition December 2000, 28 (12) 1484-1486;
Nakajima, Miki
- You have accessRoles of Cytochromes P450 1A2, 2A6, and 2C8 in 5-Fluorouracil Formation from Tegafur, an Anticancer Prodrug, in Human Liver MicrosomesTomoko Komatsu, Hiroshi Yamazaki, Noriaki Shimada, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition December 2000, 28 (12) 1457-1463;
Nation, Roger L.
- You have accessDisposition of l-Carnitine and Its Short-Chain Esters, Acetyl-l-carnitine and Propionyl-l-carnitine, in the Rat Isolated Perfused LiverAngelo Mancinelli, Antonio Longo, Roger L. Nation and Allan M. EvansDrug Metabolism and Disposition December 2000, 28 (12) 1401-1404;
Nelson, Sidney D.
- You have accessInvolvement of Human Cytochrome P450 2D6 in the Bioactivation of AcetaminophenHaijun Dong, Robert L. Haining, Kenneth E. Thummel, Allan E. Rettie and Sidney D. NelsonDrug Metabolism and Disposition December 2000, 28 (12) 1397-1400;
O
Ogilvie, Brian
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Ohtani, Tadaaki
- You have accessIn Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, a Novel Antimicrobial Agent, in Dog Liver MicrosomesKen Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Tadaaki Ohtani, Minoru Uchida and Gohachiro MiyamotoDrug Metabolism and Disposition December 2000, 28 (12) 1417-1424;
Oinonen, Teija
- You have accessEffect of Long-Term Ethanol Exposure on the Acinar Distribution of Hepatic Glutathione S-TransferaseTamara Vanhaecke, Kai O. Lindros, Teija Oinonen, Antoine Vercruysse and Vera RogiersDrug Metabolism and Disposition December 2000, 28 (12) 1470-1474;
Okura, Takashi
- You have accessDisposition and α1-Adrenoceptor Binding Characteristics of JTH-601 and Its Metabolites in Rat TissuesShizuo Yamada, Takashi Okura, Ryohei Kimura, Yoshiharu Deguchi, Yasunori Suzuki, Takuo Kobayashi and Kazuo AisakaDrug Metabolism and Disposition December 2000, 28 (12) 1487-1492;
Onderwater, Rob C. A.
- You have accessInfluence of N-Substitution of 7-Methoxy-4-(aminomethyl)-coumarin on Cytochrome P450 Metabolism and SelectivityJennifer Venhorst, Rob C. A. Onderwater, John H. N. Meerman, Jan N. M. Commandeur and Nico P. E. VermeulenDrug Metabolism and Disposition December 2000, 28 (12) 1524-1532;
P
Parkinson, Andrew
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Paxton, James W.
- You have accessIdentification of the Human Liver Cytochrome P450 Isoenzyme Responsible for the 6-Methylhydroxylation of the Novel Anticancer Drug 5,6-Dimethylxanthenone-4-acetic AcidShufeng Zhou, James W. Paxton, Malcolm D. Tingle and Philip KestellDrug Metabolism and Disposition December 2000, 28 (12) 1449-1456;
Pollack, Gary M.
- You have accessProbenecid-Associated Alterations in Valproic Acid Pharmacokinetics in Rats: Can in Vivo Disposition of Valproate Glucuronide Be Predicted from in Vitro Formation Data?E. Stacy Ward, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition December 2000, 28 (12) 1433-1439;
Přikrylová, Věra
- You have accessChemoenzymatic Preparation of Silybin β-Glucuronides and Their Biological EvaluationVladimír Kr̆en, Jitka Ulrichová, Pavel Kosina, David Stevenson, Petr Sedmera, Věra Přikrylová, Petr Halada and Vilím šsimánekDrug Metabolism and Disposition December 2000, 28 (12) 1513-1517;
R
Rahmani, Roger
- You have accessEffects of Macrolide Antibiotics on CYP3A Expression in Human and Rat Hepatocytes: Interspecies Differences in Response to TroleandomycinNathalie Ledirac, Georges de Sousa, Franck Fontaine, Constantin Agouridas, Jean Gugenheim, Giocando Lorenzon and Roger RahmaniDrug Metabolism and Disposition December 2000, 28 (12) 1391-1393;
Reist, Marianne
- You have accessVery Slow Chiral Inversion of Clopidogrel in Rats: A Pharmacokinetic and Mechanistic InvestigationMarianne Reist, Marieke Roy-de Vos, Jean-Pierre Montseny, Joachim M. Mayer, Pierre-Alain Carrupt, Yves Berger and Bernard TestaDrug Metabolism and Disposition December 2000, 28 (12) 1405-1410;
Rettie, Allan E.
- You have accessInvolvement of Human Cytochrome P450 2D6 in the Bioactivation of AcetaminophenHaijun Dong, Robert L. Haining, Kenneth E. Thummel, Allan E. Rettie and Sidney D. NelsonDrug Metabolism and Disposition December 2000, 28 (12) 1397-1400;
Rogiers, Vera
- You have accessEffect of Long-Term Ethanol Exposure on the Acinar Distribution of Hepatic Glutathione S-TransferaseTamara Vanhaecke, Kai O. Lindros, Teija Oinonen, Antoine Vercruysse and Vera RogiersDrug Metabolism and Disposition December 2000, 28 (12) 1470-1474;
Rollins, Douglas E.
- You have accessThe Incorporation of Cocaine and Metabolites into Hair: Effects of Dose and Hair PigmentationDeanna L. Hubbard, Diana G. Wilkins and Douglas E. RollinsDrug Metabolism and Disposition December 2000, 28 (12) 1464-1469;
S
Sedmera, Petr
- You have accessChemoenzymatic Preparation of Silybin β-Glucuronides and Their Biological EvaluationVladimír Kr̆en, Jitka Ulrichová, Pavel Kosina, David Stevenson, Petr Sedmera, Věra Přikrylová, Petr Halada and Vilím šsimánekDrug Metabolism and Disposition December 2000, 28 (12) 1513-1517;
Shawver, Laura K.
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Shet, Manjunath
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Shibata, Yoshihiro
- You have accessA Convenient In Vitro Screening Method for Predicting In Vivo Drug Metabolic Clearance Using Isolated Hepatocytes Suspended in SerumYoshihiro Shibata, Hiroyuki Takahashi and Yasuyuki IshiiDrug Metabolism and Disposition December 2000, 28 (12) 1518-1523;
Shimada, Noriaki
- You have accessRoles of Cytochromes P450 1A2, 2A6, and 2C8 in 5-Fluorouracil Formation from Tegafur, an Anticancer Prodrug, in Human Liver MicrosomesTomoko Komatsu, Hiroshi Yamazaki, Noriaki Shimada, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition December 2000, 28 (12) 1457-1463;
šsimánek, Vilím
- You have accessChemoenzymatic Preparation of Silybin β-Glucuronides and Their Biological EvaluationVladimír Kr̆en, Jitka Ulrichová, Pavel Kosina, David Stevenson, Petr Sedmera, Věra Přikrylová, Petr Halada and Vilím šsimánekDrug Metabolism and Disposition December 2000, 28 (12) 1513-1517;
Stevenson, David
- You have accessChemoenzymatic Preparation of Silybin β-Glucuronides and Their Biological EvaluationVladimír Kr̆en, Jitka Ulrichová, Pavel Kosina, David Stevenson, Petr Sedmera, Věra Přikrylová, Petr Halada and Vilím šsimánekDrug Metabolism and Disposition December 2000, 28 (12) 1513-1517;
Stresser, David M.
- You have accessSubstrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric SubstratesDavid M. Stresser, Andrew P. Blanchard, Stephanie D. Turner, John C. L. Erve, Andre A. Dandeneau, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition December 2000, 28 (12) 1440-1448;
Suzuki, Yasunori
- You have accessDisposition and α1-Adrenoceptor Binding Characteristics of JTH-601 and Its Metabolites in Rat TissuesShizuo Yamada, Takashi Okura, Ryohei Kimura, Yoshiharu Deguchi, Yasunori Suzuki, Takuo Kobayashi and Kazuo AisakaDrug Metabolism and Disposition December 2000, 28 (12) 1487-1492;
T
Takahashi, Hiroyuki
- You have accessA Convenient In Vitro Screening Method for Predicting In Vivo Drug Metabolic Clearance Using Isolated Hepatocytes Suspended in SerumYoshihiro Shibata, Hiroyuki Takahashi and Yasuyuki IshiiDrug Metabolism and Disposition December 2000, 28 (12) 1518-1523;
Testa, Bernard
- You have accessVery Slow Chiral Inversion of Clopidogrel in Rats: A Pharmacokinetic and Mechanistic InvestigationMarianne Reist, Marieke Roy-de Vos, Jean-Pierre Montseny, Joachim M. Mayer, Pierre-Alain Carrupt, Yves Berger and Bernard TestaDrug Metabolism and Disposition December 2000, 28 (12) 1405-1410;
Thummel, Kenneth E.
- You have accessInvolvement of Human Cytochrome P450 2D6 in the Bioactivation of AcetaminophenHaijun Dong, Robert L. Haining, Kenneth E. Thummel, Allan E. Rettie and Sidney D. NelsonDrug Metabolism and Disposition December 2000, 28 (12) 1397-1400;
Tingle, Malcolm D.
- You have accessIdentification of the Human Liver Cytochrome P450 Isoenzyme Responsible for the 6-Methylhydroxylation of the Novel Anticancer Drug 5,6-Dimethylxanthenone-4-acetic AcidShufeng Zhou, James W. Paxton, Malcolm D. Tingle and Philip KestellDrug Metabolism and Disposition December 2000, 28 (12) 1449-1456;
Turner, Stephanie D.
- You have accessSubstrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric SubstratesDavid M. Stresser, Andrew P. Blanchard, Stephanie D. Turner, John C. L. Erve, Andre A. Dandeneau, Vaughn P. Miller and Charles L. CrespiDrug Metabolism and Disposition December 2000, 28 (12) 1440-1448;
U
Uchida, Minoru
- You have accessIn Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, a Novel Antimicrobial Agent, in Dog Liver MicrosomesKen Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Tadaaki Ohtani, Minoru Uchida and Gohachiro MiyamotoDrug Metabolism and Disposition December 2000, 28 (12) 1417-1424;
Ulrichová, Jitka
- You have accessChemoenzymatic Preparation of Silybin β-Glucuronides and Their Biological EvaluationVladimír Kr̆en, Jitka Ulrichová, Pavel Kosina, David Stevenson, Petr Sedmera, Věra Přikrylová, Petr Halada and Vilím šsimánekDrug Metabolism and Disposition December 2000, 28 (12) 1513-1517;
Umehara, Ken
- You have accessIn Vitro Characterization of the Oxidative Cleavage of the Octyl Side Chain of Olanexidine, a Novel Antimicrobial Agent, in Dog Liver MicrosomesKen Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Tadaaki Ohtani, Minoru Uchida and Gohachiro MiyamotoDrug Metabolism and Disposition December 2000, 28 (12) 1417-1424;
V
Van den Mooter, Guy
- You have accessIncreased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal MetabolismJan Van Gelder, Sven Deferme, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget and Parick AugustijnsDrug Metabolism and Disposition December 2000, 28 (12) 1394-1396;
Van Gelder, Jan
- You have accessIncreased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal MetabolismJan Van Gelder, Sven Deferme, Pieter Annaert, Lieve Naesens, Erik De Clercq, Guy Van den Mooter, Renaat Kinget and Parick AugustijnsDrug Metabolism and Disposition December 2000, 28 (12) 1394-1396;
van Giersbergen, Paul
- You have accessComparative Tolerability, Pharmacodynamics, and Pharmacokinetics of a Metabolite of a Quinolizinone Hypnotic and Zolpidem in Healthy SubjectsJasper Dingemanse, Michele Bury, Yasmin Hussain and Paul van GiersbergenDrug Metabolism and Disposition December 2000, 28 (12) 1411-1416;
Vanhaecke, Tamara
- You have accessEffect of Long-Term Ethanol Exposure on the Acinar Distribution of Hepatic Glutathione S-TransferaseTamara Vanhaecke, Kai O. Lindros, Teija Oinonen, Antoine Vercruysse and Vera RogiersDrug Metabolism and Disposition December 2000, 28 (12) 1470-1474;
Venhorst, Jennifer
- You have accessInfluence of N-Substitution of 7-Methoxy-4-(aminomethyl)-coumarin on Cytochrome P450 Metabolism and SelectivityJennifer Venhorst, Rob C. A. Onderwater, John H. N. Meerman, Jan N. M. Commandeur and Nico P. E. VermeulenDrug Metabolism and Disposition December 2000, 28 (12) 1524-1532;
Venkatakrishnan, Karthik
- You have accessComparison between Cytochrome P450 (CYP) Content and Relative Activity Approaches to Scaling from cDNA-Expressed CYPs to Human Liver Microsomes: Ratios of Accessory Proteins as Sources of Discrepancies between the ApproachesKarthik Venkatakrishnan, Lisa L. von Moltke, Michael H. Court, Jerold S. Harmatz, Charles L. Crespi and David J. GreenblattDrug Metabolism and Disposition December 2000, 28 (12) 1493-1504;
Vercruysse, Antoine
- You have accessEffect of Long-Term Ethanol Exposure on the Acinar Distribution of Hepatic Glutathione S-TransferaseTamara Vanhaecke, Kai O. Lindros, Teija Oinonen, Antoine Vercruysse and Vera RogiersDrug Metabolism and Disposition December 2000, 28 (12) 1470-1474;
Vermeulen, Nico P. E.
- You have accessInfluence of N-Substitution of 7-Methoxy-4-(aminomethyl)-coumarin on Cytochrome P450 Metabolism and SelectivityJennifer Venhorst, Rob C. A. Onderwater, John H. N. Meerman, Jan N. M. Commandeur and Nico P. E. VermeulenDrug Metabolism and Disposition December 2000, 28 (12) 1524-1532;
von Moltke, Lisa L.
- You have accessComparison between Cytochrome P450 (CYP) Content and Relative Activity Approaches to Scaling from cDNA-Expressed CYPs to Human Liver Microsomes: Ratios of Accessory Proteins as Sources of Discrepancies between the ApproachesKarthik Venkatakrishnan, Lisa L. von Moltke, Michael H. Court, Jerold S. Harmatz, Charles L. Crespi and David J. GreenblattDrug Metabolism and Disposition December 2000, 28 (12) 1493-1504;
Vos, Marieke Roy-de
- You have accessVery Slow Chiral Inversion of Clopidogrel in Rats: A Pharmacokinetic and Mechanistic InvestigationMarianne Reist, Marieke Roy-de Vos, Jean-Pierre Montseny, Joachim M. Mayer, Pierre-Alain Carrupt, Yves Berger and Bernard TestaDrug Metabolism and Disposition December 2000, 28 (12) 1405-1410;
W
Wagner, Greg
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Ward, E. Stacy
- You have accessProbenecid-Associated Alterations in Valproic Acid Pharmacokinetics in Rats: Can in Vivo Disposition of Valproate Glucuronide Be Predicted from in Vitro Formation Data?E. Stacy Ward, Gary M. Pollack and Kim L. R. BrouwerDrug Metabolism and Disposition December 2000, 28 (12) 1433-1439;
Weber, Wendell W.
- You have accessPharmacogenetics of the ArylamineN-Acetyltransferases: A Symposium in Honor of Wendell W. WeberDavid W. Hein, Charlene A. McQueen, Denis M. Grant, Geoffrey H. Goodfellow, Fred F. Kadlubar and Wendell W. WeberDrug Metabolism and Disposition December 2000, 28 (12) 1425-1432;
Wilkins, Diana G.
- You have accessThe Incorporation of Cocaine and Metabolites into Hair: Effects of Dose and Hair PigmentationDeanna L. Hubbard, Diana G. Wilkins and Douglas E. RollinsDrug Metabolism and Disposition December 2000, 28 (12) 1464-1469;
Y
Yamada, Shizuo
- You have accessDisposition and α1-Adrenoceptor Binding Characteristics of JTH-601 and Its Metabolites in Rat TissuesShizuo Yamada, Takashi Okura, Ryohei Kimura, Yoshiharu Deguchi, Yasunori Suzuki, Takuo Kobayashi and Kazuo AisakaDrug Metabolism and Disposition December 2000, 28 (12) 1487-1492;
Yamamura, Naotoshi
- You have accessPanipenum, A Carbapenem Antibiotic, Increases the Level of Hepatic Udp-Glucuronic Acid in RatsNaotoshi Yamamura, Kaoru Imura-Miyoshi and Hideo NaganumaDrug Metabolism and Disposition December 2000, 28 (12) 1484-1486;
Yamazaki, Hiroshi
- You have accessRoles of Cytochromes P450 1A2, 2A6, and 2C8 in 5-Fluorouracil Formation from Tegafur, an Anticancer Prodrug, in Human Liver MicrosomesTomoko Komatsu, Hiroshi Yamazaki, Noriaki Shimada, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition December 2000, 28 (12) 1457-1463;
Yang, Cheng
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Yokoi, Tsuyoshi
- You have accessRoles of Cytochromes P450 1A2, 2A6, and 2C8 in 5-Fluorouracil Formation from Tegafur, an Anticancer Prodrug, in Human Liver MicrosomesTomoko Komatsu, Hiroshi Yamazaki, Noriaki Shimada, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition December 2000, 28 (12) 1457-1463;
Z
Zhang, Hongbing
- You have accessBiotransformation of the Anti-Angiogenic Compound SU5416Lida Antonian, Hongbing Zhang, Cheng Yang, Greg Wagner, Laura K. Shawver, Manjunath Shet, Brian Ogilvie, Ajay Madan and Andrew ParkinsonDrug Metabolism and Disposition December 2000, 28 (12) 1505-1512;
Zhou, Shufeng
- You have accessIdentification of the Human Liver Cytochrome P450 Isoenzyme Responsible for the 6-Methylhydroxylation of the Novel Anticancer Drug 5,6-Dimethylxanthenone-4-acetic AcidShufeng Zhou, James W. Paxton, Malcolm D. Tingle and Philip KestellDrug Metabolism and Disposition December 2000, 28 (12) 1449-1456;