Table of Contents

Articles

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  Drug Interactions with Calcium Channel Blockers: Possible Involvement of Metabolite-Intermediate Complexation with CYP3A

  Bennett Ma, Thomayant Prueksaritanont and Jiunn H. Lin

  Drug Metabolism and Disposition February 2000, 28 (2) 125-130;
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  Antisense Oligonucleotides Targeted to thep53 Gene Modulate Liver Regeneration In Vivo

  Vikram Arora and Patrick L. Iversen

  Drug Metabolism and Disposition February 2000, 28 (2) 131-138;
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  Tissue- and Gender-Specific Expression ofN-Acetyltransferase 2 (Nat2*) during Development of the Outbred Mouse Strain CD-1

  Lourdes Estrada, Kimon C. Kanelakis, Gerald N. Levy and Wendell W. Weber

  Drug Metabolism and Disposition February 2000, 28 (2) 139-146;
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  Metabolism and Pharmacokinetics, in the Rat, of (R)-N-(2-Heptyl)Methyl-Propargylamine (R-2HMP), A New Potent Monoamine Oxidase Inhibitor and Antiapoptotic Agent

  David A. Durden, Lillian E. Dyck, Bruce A. Davis, Ya-Dong Liu and Alan A. Boulton

  Drug Metabolism and Disposition February 2000, 28 (2) 147-154;
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  Pharmacokinetics of the Rapid-Acting Insulin Analog, Insulin Aspart, in Rats, Dogs, and Pigs, and Pharmacodynamics of Insulin Aspart in Pigs

  Anne Plum, Henrik Agersø and Lennart Andersen

  Drug Metabolism and Disposition February 2000, 28 (2) 155-160;
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  Prediction of Pharmacokinetic Drug/Drug Interactions from In Vitro Data: Interactions of the Nonsteroidal Anti-Inflammatory Drug Lornoxicam with Oral Anticoagulants

  Christopher Kohl and Michael Steinkellner

  Drug Metabolism and Disposition February 2000, 28 (2) 161-168;
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  Population-Specific Polymorphisms of the HumanFMO3 Gene: Significance for Detoxication

  John R. Cashman, Beverly R. Akerman, Susan M. Forrest and Eileen P. Treacy

  Drug Metabolism and Disposition February 2000, 28 (2) 169-173;
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  Molecular Dynamics Simulation of Metallothionein-Drug Complexes

  Zoltán Szilágyi and Catherine Fenselau

  Drug Metabolism and Disposition February 2000, 28 (2) 174-179;
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  Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Primary Cultures of Rat Alveolar Type II Cells

  Eberhard Schrader, Karen I. Hirsch-Ernst, Ekkehard Scholz, Georg F. Kahl and Heidi Foth

  Drug Metabolism and Disposition February 2000, 28 (2) 180-185;
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  Dexamethasone Differentially Regulates Expression of Carboxylesterase Genes in Humans and Rats

  Weizhu Zhu, Li Song, He Zhang, Lynn Matoney, Edward LeCluyse and Bingfang Yan

  Drug Metabolism and Disposition February 2000, 28 (2) 186-191;
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  Disposition of Radioactivity in Fischer 344 Rats after Single and Multiple Inhalation Exposure to [¹⁴C]Octamethylcyclotetrasiloxane ([¹⁴C]D₄)

  Kathleen P. Plotzke, Steven D. Crofoot, Eckhardt S. Ferdinandi, J. Gregory Beattie, Richard H. Reitz, Debra A. McNett and Robert G. Meeks

  Drug Metabolism and Disposition February 2000, 28 (2) 192-204;
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  Pharmacokinetics of All-trans Retinoic Acid, 13-cis Retinoic Acid, and Fenretinide in Plasma and Brain of Rat

  François Le Doze, Daniele Debruyne, Françoise Albessard, Louisa Barre and Gilles Louis Defer

  Drug Metabolism and Disposition February 2000, 28 (2) 205-208;
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  Biliary Metabolites of β-Artemether in Rats: Biotransformations of an Antimalarial Endoperoxide

  James L. Maggs, Laurence P. D. Bishop, Geoffrey Edwards, Paul M. O'Neill, Stephen A. Ward, Peter A. Winstanley and B. Kevin Park

  Drug Metabolism and Disposition February 2000, 28 (2) 209-217;
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  o-Hydroxyphenylacetaldehyde Is a Hepatotoxic Metabolite of Coumarin

  Stephanie L. Born, Joanna K. Hu and Lois D. Lehman-McKeeman

  Drug Metabolism and Disposition February 2000, 28 (2) 218-223;
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  A New Physiologically Based, Segregated-Flow Model to Explain Route-Dependent Intestinal Metabolism

  Diem Cong, Margaret Doherty and K. Sandy Pang

  Drug Metabolism and Disposition February 2000, 28 (2) 224-235;
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  Systemic Coadministration of Chloramphenicol with Intravenous but not Intracerebroventricular Morphine Markedly Increases Morphine Antinociception and Delays Development of Antinociceptive Tolerance in Rats

  Maree T. Smith, Carsten K. Nielsen, Megan Y. C. Lim-Fraser, Andrew W. E. Wright and Michael Lau

  Drug Metabolism and Disposition February 2000, 28 (2) 236-244;