Table of Contents

Articles

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  Bioactivation and Covalent Binding of Hydroxyfluperlapine in Human Neutrophils: Implications for Fluperlapine-Induced Agranulocytosis

  W. George Lai, Iain Gardner, Nasir Zahid and Jack P. Uetrecht

  Drug Metabolism and Disposition March 2000, 28 (3) 255-263;
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  The Role of mdr1a P-Glycoprotein in the Biliary and Intestinal Secretion of Doxorubicin and Vinblastine in Mice

  Judith van Asperen, Olaf van Tellingen and Jos H. Beijnen

  Drug Metabolism and Disposition March 2000, 28 (3) 264-267;
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  The Glucocorticoid Receptor Is Essential for Induction of Cytochrome P-4502B by Steroids but Not for Drug or Steroid Induction of CYP3A or P-450 Reductase in Mouse Liver

  Erin G. Schuetz, Wolfgang Schmid, Gunther Schutz, Cynthia Brimer, Kazuto Yasuda, Tetsuya Kamataki, Lester Bornheim, Kathy Myles and Timothy J. Cole

  Drug Metabolism and Disposition March 2000, 28 (3) 268-278;
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  Diphenhydramine Disposition in the Sheep Maternal-Placental-Fetal Unit: Gestational Age, Plasma Drug Protein Binding, and Umbilical Blood Flow Effects on Clearance

  Sanjeev Kumar, George R. Tonn, K. Wayne Riggs and Dan W. Rurak

  Drug Metabolism and Disposition March 2000, 28 (3) 279-285;
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  Incorporation and Retention of RadiolabeledS-(+)-and R-(−)-Methamphetamine andS(+)- andR(−)-N-(n-butyl)-amphetamine in Mouse Hair after Systemic Administration

  Peter R. Stout, David J. Claffey and James A. Ruth

  Drug Metabolism and Disposition March 2000, 28 (3) 286-291;
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  Human Cytochrome P-450 Metabolism of Retinals to Retinoic Acids

  Qing-Yu Zhang, Deborah Dunbar and Laurence Kaminsky

  Drug Metabolism and Disposition March 2000, 28 (3) 292-297;
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  Analysis of Soy Isoflavone Conjugation In Vitro and in Human Blood Using Liquid Chromatography-Mass Spectrometry

  Daniel R. Doerge, Hebron C. Chang, Mona I. Churchwell and C. Lee Holder

  Drug Metabolism and Disposition March 2000, 28 (3) 298-307;
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  Metabolism and Excretion of [¹⁴C]Celecoxib in Healthy Male Volunteers

  Susan K. Paulson, Jeremy D. Hribar, Norman W. K. Liu, Elisabeth Hajdu, Roy H. Bible, Antoni Piergies and Aziz Karim

  Drug Metabolism and Disposition March 2000, 28 (3) 308-314;
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  Biosynthesis Of All-trans-Retinoic Acid from All-trans-Retinol: Catalysis of All-trans-Retinol Oxidation by Human P-450 Cytochromes

  Hao Chen, William N. Howald and Mont R. Juchau

  Drug Metabolism and Disposition March 2000, 28 (3) 315-322;
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  Input Rate as a Major Determinant of Furosemide Pharmacodynamics: Influence of Fluid Replacement and Hypoalbuminemia

  Gilberto Castañeda-Hernández, Josep Vergés, Vincent Pichette, Lucie Héroux, Gilles Caillé and Patrick du Souich

  Drug Metabolism and Disposition March 2000, 28 (3) 323-328;
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  Interactions of HIV Protease Inhibitors with a Human Organic Cation Transporter in a Mammalian Expression System

  Lei Zhang, Wenche Gorset, Carla B. Washington, Terrence F. Blaschke, Deanna L. Kroetz and Kathleen M. Giacomini

  Drug Metabolism and Disposition March 2000, 28 (3) 329-334;
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  m-Hydroxy Benzoylecgonine Recovery in Fetal Guinea Pigs

  Lynn M. Iwamoto, Christine M. Moore, Naomi Fujiwara, Michael J. Christ, Delores M. Gries and Kenneth T. Nakamura

  Drug Metabolism and Disposition March 2000, 28 (3) 335-338;
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  On the Metabolism of the Amphetamine-Derived Antispasmodic Drug Mebeverine: Gas Chromatography-Mass Spectrometry Studies on Rat Liver Microsomes and on Human Urine

  Thomas Kraemer, Joerg Bickeboeller-Friedrich and Hans H. Maurer

  Drug Metabolism and Disposition March 2000, 28 (3) 339-347;
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  Selective Involvement of Cytochrome P450 2D Subfamily in In Vivo 4-Hydroxylation of Amphetamine in Rat

  Michael Y. L. Law, Matthew H. Slawson and David E. Moody

  Drug Metabolism and Disposition March 2000, 28 (3) 348-353;
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  CYP2C19 Participates in Tolbutamide Hydroxylation by Human Liver Microsomes

  Michael R. Wester, Jerome M. Lasker, Eric F. Johnson and Judy L. Raucy

  Drug Metabolism and Disposition March 2000, 28 (3) 354-359;
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  Human Cytochrome P-450 3A4: In Vitro Drug-Drug Interaction Patterns Are Substrate-Dependent

  Regina W. Wang, Deborah J. Newton, Nini Liu, William M. Atkins and Anthony Y. H. Lu

  Drug Metabolism and Disposition March 2000, 28 (3) 360-366;
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  Butyrylcholinesterase Accelerates Cocaine Metabolism: In Vitro and In Vivo Effects in Nonhuman Primates and Humans

  Gilberto N. Carmona, Rebecca A. Jufer, Steven R. Goldberg, David A. Gorelick, Nigel H. Greig, Qian-Sheng Yu, Edward J. Cone and Charles W. Schindler

  Drug Metabolism and Disposition March 2000, 28 (3) 367-371;