Table of Contents

Articles

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  Pharmacokinetics of a Model Organic Nitrite Inhalant and its Alcohol Metabolite in Rats

  William Kielbasa and Ho-Leung Fung

  Drug Metabolism and Disposition April 2000, 28 (4) 386-391;
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  In Vitro Biotransformation of Sildenafil (Viagra): Identification of Human Cytochromes and Potential Drug Interactions

  Jill S. Warrington, Richard I. Shader, Lisa L. von Moltke and David J. Greenblatt

  Drug Metabolism and Disposition April 2000, 28 (4) 392-397;
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  Thioesterification of 2-Arylpropionic Acids by Recombinant Acyl-Coenzyme A Synthetases (ACS1 and ACS2)

  Cendrine Sevoz, Etienne Benoit and Thierry Buronfosse

  Drug Metabolism and Disposition April 2000, 28 (4) 398-402;
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  Pharmacokinetics, Biliary Excretion, and Tissue Distribution of Novel Anti-HIV Agents, Cosalane and Dihydrocosalane, in Sprague-Dawley Rats

  Kameswara R. Kuchimanchi, Chandrasekhar Udata, Thomas P. Johnston and Ashim K. Mitra

  Drug Metabolism and Disposition April 2000, 28 (4) 403-408;
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  Studies on the Cytochrome P450 (CYP)-Mediated Metabolic Properties of Miocamycin: Evaluation of the Possibility of a Metabolic Intermediate Complex Formation with CYP, and Identification of the Human CYP Isoforms

  Mie Kasahara, Hisashi Suzuki and Izumi Komiya

  Drug Metabolism and Disposition April 2000, 28 (4) 409-417;
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  Disposition in Rats of N-Pyridinium-propyl-cyclam,N-Triethylammonium-propyl-cyclam, andN-[Triethylammonium]-3-propyl-[15]ane-N5, Potential Cartilage Imaging Agents

  Jean-Claude Maurizis, Maryse Rapp, Colette Nicolas, Monique Ollier, Michel Verny and Jean-Claude Madelmont

  Drug Metabolism and Disposition April 2000, 28 (4) 418-422;
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  Pharmacokinetics, Metabolism, and Excretion of Irinotecan (CPT-11) Following I.V. Infusion of [¹⁴C]CPT-11 in Cancer Patients

  John Greg Slatter, Larry J. Schaaf, James P. Sams, Kenneth L. Feenstra, Mark G. Johnson, Paul A. Bombardt, Karen Sue Cathcart, Michael T. Verburg, Laura K. Pearson, Linda D. Compton, Langdon L. Miller, David S. Baker, Caroline V. Pesheck and Raymond S. Lord

  Drug Metabolism and Disposition April 2000, 28 (4) 423-433;
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  The Synthesis, In Vitro Reactivity, and Evidence for Formation in Humans of 5-Phenyl-1,3-oxazinane-2,4-dione, a Metabolite of Felbamate

  Charles D. Thompson, Thomas A. Miller, Mary T. Barthen, Christine M. Dieckhaus, R. Duane Sofia and Timothy L. Macdonald

  Drug Metabolism and Disposition April 2000, 28 (4) 434-439;
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  Porcine Kidney Microsomal Cysteine S-ConjugateN-Acetyltransferase-CatalyzedN-Acetylation of Haloalkene-Derived CysteineS-Conjugates

  Torsten Kraus, Viuita Uttamsingh, M.W. Anders and Sabine Wolf

  Drug Metabolism and Disposition April 2000, 28 (4) 440-445;
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  Metabolism and Disposition of Moxonidine in Fischer 344 Rats

  Minxia M. He, Trent L. Abraham, Thomas J. Lindsay, Sylvia H. Chay, Boris A. Czeskis and Lisa A. Shipley

  Drug Metabolism and Disposition April 2000, 28 (4) 446-459;
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  Route-Dependent Nonlinear Pharmacokinetics of a Novel HIV Protease Inhibitor: Involvement of Enzyme Inactivation

  Jiunn H. Lin, I-Wu Chen, Masato Chiba, Joy A. Nishime and Florencia A. deLuna

  Drug Metabolism and Disposition April 2000, 28 (4) 460-466;
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  Prediction of In Vivo Drug-Drug Interactions Based on Mechanism-based Inhibition from In Vitro Data: Inhibition of 5-Fluorouracil Metabolism by (E)-5-(2-Bromovinyl)uracil

  Shin-ichi Kanamitsu, Kiyomi Ito, Haruhiro Okuda, Kenichiro Ogura, Tadashi Watabe, Kei Muro and Yuichi Sugiyama

  Drug Metabolism and Disposition April 2000, 28 (4) 467-474;
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  Prediction of in Vivo Drug-Drug Interactions between Tolbutamide and Various Sulfonamides in Humans Based on in Vitro Experiments

  Kanji Komatsu, Kiyomi Ito, Yukiko Nakajima, Shin-ichi Kanamitsu, Susumu Imaoka, Yoshihiko Funae, Carol E. Green, Charles A. Tyson, Noriaki Shimada and Yuichi Sugiyama

  Drug Metabolism and Disposition April 2000, 28 (4) 475-481;
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  Effects of Long-Term Grapefruit Juice Ingestion on Nifedipine Pharmacokinetics: Induction of Rat Hepatic P-450 by Grapefruit Juice

  Kiminori Mohri, Yoshihiro Uesawa and Ken-ichi Sagawa

  Drug Metabolism and Disposition April 2000, 28 (4) 482-486;
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  The N-Acetylation of Arsanilic Acid In Vitro by Mammalian Enzymes

  Gladys S. Bayse, Laide A. Jinadu, Kiana L. Shaw and Kelita L. Wiley

  Drug Metabolism and Disposition April 2000, 28 (4) 487-492;