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Research ArticleArticle

Route-Dependent Nonlinear Pharmacokinetics of a Novel HIV Protease Inhibitor: Involvement of Enzyme Inactivation

Jiunn H. Lin, I-Wu Chen, Masato Chiba, Joy A. Nishime and Florencia A. deLuna
Drug Metabolism and Disposition April 2000, 28 (4) 460-466;

Article Information

vol. 28 no. 4 460-466
PubMed 
10725315
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 20, 1999
  • Accepted January 4, 2000
  • Published online April 1, 2000.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jiunn H. Lin,
  2. I-Wu Chen,
  3. Masato Chiba,
  4. Joy A. Nishime and
  5. Florencia A. deLuna
  1. Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania
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    Research ArticleArticle

    Route-Dependent Nonlinear Pharmacokinetics of a Novel HIV Protease Inhibitor: Involvement of Enzyme Inactivation

    Jiunn H. Lin, I-Wu Chen, Masato Chiba, Joy A. Nishime and Florencia A. deLuna
    Drug Metabolism and Disposition April 1, 2000, 28 (4) 460-466;
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