Table of Contents

Articles

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  Biliary and Urinary Metabolic Profiles of 1,2-Diethyl-3-hydroxypyridin-4-one (CP94) in the Rat

  Shu L. Lu, Itsaraet Gosriwatana, Ding Y. Liu, Zu D. Liu, Anthony I. Mallet and Robert C. Hider

  Drug Metabolism and Disposition August 2000, 28 (8) 873-879;
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  Metabolism of para-Aminophenol by Rat Hepatocytes

  Zimeng Yan, John G. Nikelly, Lewis Killmer and Joan B. Tarloff

  Drug Metabolism and Disposition August 2000, 28 (8) 880-886;
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  Oxidative Cleavage of the Octyl Side Chain of 1-(3,4-Dichlorobenzyl)-5-Octylbiguanide (OPB-2045) in Rat and Dog Liver Preparations

  Ken Umehara, Shoji Kudo, Yukihiro Hirao, Seiji Morita, Minoru Uchida, Masaaki Odomi and Gohachiro Miyamoto

  Drug Metabolism and Disposition August 2000, 28 (8) 887-894;
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  Mibefradil Is a P-Glycoprotein Substrate and a Potent Inhibitor of Both P-Glycoprotein and CYP3A In Vitro

  Christoph Wandel, Richard B. Kim, F. Peter Guengerich and Alastair J. J. Wood

  Drug Metabolism and Disposition August 2000, 28 (8) 895-898;
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  Isolation and Identification of Urinary Metabolites of Porfiromycin in Dogs and Humans

  Wensheng Lang, John Mao, Terrence W. Doyle and Bijan Almassian

  Drug Metabolism and Disposition August 2000, 28 (8) 899-904;
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  Mechanism-Based Inactivation of Cytochromes P450 2B1 and P450 2B6 by 2-Phenyl-2-(1-piperidinyl)propane

  Jarin Chun, Ute M. Kent, Rachel M. Moss, Lawrence M. Sayre and Paul F. Hollenberg

  Drug Metabolism and Disposition August 2000, 28 (8) 905-911;
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  Ontogeny of Valproic Acid Disposition and Metabolism: A Developmental Study in Postnatal Lambs and Adult Sheep

  Harvey Wong, Sanjeev Kumar, Dan W. Rurak, Eddie Kwan, Frank S. Abbott and K. Wayne Riggs

  Drug Metabolism and Disposition August 2000, 28 (8) 912-919;
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  Assessment of the Metabolic Chiral Inversion ofd-Leucine in Rat by Gas Chromatography-Mass Spectrometry Combined with a Stable Isotope Dilution Analysis

  Hiroshi Hasegawa, Takehisa Matsukawa, Yoshihiko Shinohara and Takao Hashimoto

  Drug Metabolism and Disposition August 2000, 28 (8) 920-924;
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  Pharmacokinetic Profiles in Rats After Intravenous, Oral, or Dermal Administration of Dapsone

  David R. Helton, David W. Osborne, Sharon K. Pierson, Michael H. Buonarati and Robert A. Bethem

  Drug Metabolism and Disposition August 2000, 28 (8) 925-929;
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  Concurrent Flavin-Containing Monooxygenase Down-Regulation and Cytochrome P-450 Induction by Dietary Indoles in Rat: Implications for Drug-Drug Interaction

  Sirinmas Katchamart, David M. Stresser, Shangara S. Dehal, David Kupfer and David E. Williams

  Drug Metabolism and Disposition August 2000, 28 (8) 930-936;
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  Identification of CYP3A4 as the Enzyme Involved in the Mono-N-Dealkylation of Disopyramide Enantiomers in Humans

  Hirotoshi Echizen, Michika Tanizaki, Jun Tatsuno, Kan Chiba, Teresa Berwick, Masayoshi Tani, Frank J. Gonzalez and Takashi Ishizaki

  Drug Metabolism and Disposition August 2000, 28 (8) 937-944;
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  Phenytoin Metabolism by Human Cytochrome P450: Involvement of P450 3A and 2C Forms in Secondary Metabolism and Drug-Protein Adduct Formation

  Leila Cuttle, Andrew J. Munns, Nicole A. Hogg, Justin R. Scott, Wayne D. Hooper, Ronald G. Dickinson and Elizabeth M. J. Gillam

  Drug Metabolism and Disposition August 2000, 28 (8) 945-950;
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  Glutathione S-Transferase Metabolism of the Antineoplastic Pentafluorophenylsulfonamide in Tissue Culture and Mice

  Walter P. Frankmoelle, Julio C. Medina, Bei Shan, Mathew R. Narbut and Holger Beckmann

  Drug Metabolism and Disposition August 2000, 28 (8) 951-958;
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  Involvement of CYP1A2 and CYP3A4 in LidocaineN-Deethylation and 3-Hydroxylation in Humans

  Jun-Sheng Wang, Janne T. Backman, Päivi Taavitsainen, Pertti J. Neuvonen and Kari T. Kivistö

  Drug Metabolism and Disposition August 2000, 28 (8) 959-965;
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  Stereoselective Metabolism of Omeprazole by Human Cytochrome P450 Enzymes

  Angela Äbelö, Tommy B. Andersson, Madeleine Antonsson, Anna Knuts Naudot, Inger Skånberg and Lars Weidolf

  Drug Metabolism and Disposition August 2000, 28 (8) 966-972;
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  Disposition of Radiolabeled Ifetroban in Rats, Dogs, Monkeys, and Humans

  Randy C. Dockens, Kenneth S. Santone, James G. Mitroka, Richard A. Morrison, Mohammed Jemal, Douglas S. Greene and Rashmi H. Barbhaiya

  Drug Metabolism and Disposition August 2000, 28 (8) 973-980;
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  Cloning of Canine Cytochrome P450 2E1 cDNA: Identification and Characterization of Two Variant Alleles

  Susan M. Lankford, Stephen A. Bai and Joyce A. Goldstein

  Drug Metabolism and Disposition August 2000, 28 (8) 981-986;
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  Detection of Cytochrome P450 and Other Drug-Metabolizing Enzyme mRNAs in Peripheral Blood Mononuclear Cells Using DNA Arrays

  Linh T. Nguyen, Murali Ramanathan, Bianca Weinstock-Guttman, Kiran Dole, Colleen Miller, Margaret Planter, Kara Patrick, Carol Brownscheidle and Lawrence D. Jacobs

  Drug Metabolism and Disposition August 2000, 28 (8) 987-993;
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  Three- and Four-Dimensional-Quantitative Structure Activity Relationship (3D/4D-QSAR) Analyses of CYP2C9 Inhibitors

  Sean Ekins, Gianpaolo Bravi, Shelly Binkley, Jennifer S. Gillespie, Barbara J. Ring, James H. Wikel and Steven A Wrighton

  Drug Metabolism and Disposition August 2000, 28 (8) 994-1002;
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  Size Limits of Thiocarbamides Accepted as Substrates by Human Flavin-Containing Monooxygenase 1

  Young Mi Kim and Daniel M. Ziegler

  Drug Metabolism and Disposition August 2000, 28 (8) 1003-1006;