Table of Contents

Articles

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  Early Events in the Induction of Rat Hepatic UDP-Glucuronosyltransferases, Glutathione S-Transferase, and Microsomal Epoxide Hydrolase by 1,7-Phenanthroline: Comparison with Oltipraz, tert-Butyl-4-hydroxyanisole, andtert-Butylhydroquinone

  John G. Lamb and Michael R. Franklin

  Drug Metabolism and Disposition September 2000, 28 (9) 1018-1023;
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  O-Methylation of Tea Polyphenols Catalyzed by Human Placental Cytosolic Catechol-O-Methyltransferase

  Bao Ting Zhu, Ushma K. Patel, May Xiaoxin Cai and Allan H. Conney

  Drug Metabolism and Disposition September 2000, 28 (9) 1024-1030;
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  An In Vitro Model for Predicting In Vivo Inhibition of Cytochrome P450 3A4 by Metabolic Intermediate Complex Formation

  Bradley S. Mayhew, David R. Jones and Stephen D. Hall

  Drug Metabolism and Disposition September 2000, 28 (9) 1031-1037;
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  Effect of Aging on Tryptophan Hydroxylase in Rat Brain: Implications on Serotonin Level

  Azher M. Hussain and Ashim K. Mitra

  Drug Metabolism and Disposition September 2000, 28 (9) 1038-1042;
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  Cytochrome P450 3A4-Mediated Interaction of Diclofenac and Quinidine

  Jason S. Ngui, Wei Tang, Ralph A. Stearns, Magang Shou, Randall R. Miller, Yong Zhang, Jiunn H. Lin and Thomas A. Baillie

  Drug Metabolism and Disposition September 2000, 28 (9) 1043-1050;
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  Catalysis of the 4-Hydroxylation of Retinoic Acids by Cyp3a7 in Human Fetal Hepatic Tissues

  Hao Chen, Alan G. Fantel and Mont R. Juchau

  Drug Metabolism and Disposition September 2000, 28 (9) 1051-1057;
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  The Disposition of Saquinavir in Normal and P-glycoprotein Deficient Mice, Rats, and in Cultured Cells

  Carla B. Washington, Hugh R. Wiltshire, Martha Man, Tina Moy, Steve R. Harris, Eric Worth, Paul Weigl, Zhenmin Liang, David Hall, Lorraine Marriott and Terrence F. Blaschke

  Drug Metabolism and Disposition September 2000, 28 (9) 1058-1062;
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  A Simple Colorimetric Assay for Phenotyping the Major Human Thermostable Phenol Sulfotransferase (SULT1A1) Using Platelet Cytosols

  Lynn T. Frame, Shogo Ozawa, Susan A. Nowell, Hsien-Chang Chou, Robert R. DeLongchamp, Daniel R. Doerge, Nicholas P. Lang and Fred F. Kadlubar

  Drug Metabolism and Disposition September 2000, 28 (9) 1063-1068;
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  Metabolism of Ezlopitant, a Nonpeptidic Substance P Receptor Antagonist, in Liver Microsomes: Enzyme Kinetics, Cytochrome P450 Isoform Identity, and In Vitro-In Vivo Correlation

  R. Scott Obach

  Drug Metabolism and Disposition September 2000, 28 (9) 1069-1076;
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  Induction of UDP-Glucuronosyltransferase UGT1A1 by the Flavonoid Chrysin in the Human Hepatoma Cell Line Hep G2

  Thomas Walle, Yoko Otake, Alema Galijatovic, Joseph K. Ritter and U. Kristina Walle

  Drug Metabolism and Disposition September 2000, 28 (9) 1077-1082;
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  Isoform Specificity of N-Deacetyl Ketoconazole by Human and Rabbit Flavin-Containing Monooxygenases

  Rosita J. Rodriguez and Cristobal L. Miranda

  Drug Metabolism and Disposition September 2000, 28 (9) 1083-1086;
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    Comparison of Drug Disposition between Wild-Type and Novel Tissue-Type Plasminogen Activator Pamiteplase in Rats

  Keishi Oikawa, Takashi Watanabe and Saburou Higuchi

  Drug Metabolism and Disposition September 2000, 28 (9) 1087-1093;
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  The 1′-Hydroxylation of rac-Bufuralol by Rat Brain Microsomes

  Tanya Coleman, Ellen F. Spellman, Amin Rostami-Hodjegan, Martin S. Lennard and Geoffrey T. Tucker

  Drug Metabolism and Disposition September 2000, 28 (9) 1094-1099;
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  Increased Post-Thaw Viability and Phase I and II Biotransformation Activity in Cryopreserved Rat Liver Slices after Improvement of a Fast-Freezing Method

  I. A. M. de Graaf, D. van der Voort, J. H. F. G. Brits and H. J. Koster

  Drug Metabolism and Disposition September 2000, 28 (9) 1100-1106;
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  Immunoquantitation of FMO1 in Human Liver, Kidney, and Intestine

  Catherine K. Yeung, Dieter H. Lang, Kenneth E. Thummel and Allan E. Rettie

  Drug Metabolism and Disposition September 2000, 28 (9) 1107-1111;
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  Role of Reactive Oxygen Intermediates in the Decrease of Hepatic Cytochrome P450 Activity by Serum of Humans and Rabbits with an Acute Inflammatory Reaction

  Ayman O. S. El-Kadi, Anne-Marie Bleau, Isabelle Dumont, Hélène Maurice and Patrick du Souich

  Drug Metabolism and Disposition September 2000, 28 (9) 1112-1120;
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  CYP3A4 Is Mainly Responsibile for the Metabolism of a New Vinca Alkaloid, Vinorelbine, in Human Liver Microsomes

  Jiro Kajita, Takashi Kuwabara, Hiroyuki Kobayashi and Satoshi Kobayashi

  Drug Metabolism and Disposition September 2000, 28 (9) 1121-1127;
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  Stereoselective Metabolism of Cibenzoline, an Antiarrhythmic Drug, by Human and Rat Liver Microsomes: Possible Involvement of CYP2D and CYP3A

  Toshiro Niwa, Toshifumi Shiraga, Yasuyuki Mitani, Masato Terakawa, Yoji Tokuma and Akira Kagayama

  Drug Metabolism and Disposition September 2000, 28 (9) 1128-1134;