Different Enantioselective 9-Hydroxylation of Risperidone by the Two Human CYP2D6 and CYP3A4 Enzymes

Gunnel Tybring Ph.D., Karolinska Institutet, Department of Medical Laboratory Science & Technology, Division of Clinical Pharmacology, Huddinge University Hospital, SE-141 86 Stockholm, Sweden. E-mail:gunnel.tybring{at}labtek.ki.se

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Apr 2004	9	41	18
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Aug 2013	6	10	4
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Oct 2013	7	8	5
Nov 2013	6	8	9
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Feb 2014	1	9	6
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Apr 2014	4	8	8
May 2014	14	8	5
Jun 2014	6	13	7
Jul 2014	3	21	7
Aug 2014	4	16	6
Sep 2014	4	26	15
Oct 2014	14	17	9
Nov 2014	7	13	7
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Feb 2015	6	10	4
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Apr 2015	8	19	7
May 2015	5	14	13
Jun 2015	3	16	7
Jul 2015	7	10	13
Aug 2015	9	4	13
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Oct 2015	9	8	11
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Feb 2017	3	10	4
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Apr 2017	4	8	4
May 2017	5	12	11
Jun 2017	2	7	8
Jul 2017	2	10	8
Aug 2017	1	16	5
Sep 2017	1	16	11
Oct 2017	1	16	13
Nov 2017	3	21	6
Dec 2017	2	20	8
Jan 2018	1	18	1
Feb 2018	8	11	8
Mar 2018	1	19	4
Apr 2018	1	22	10
May 2018	2	19	14
Jun 2018	0	20	12
Jul 2018	3	9	6
Aug 2018	1	11	7
Sep 2018	3	11	3
Oct 2018	2	11	5
Nov 2018	5	13	4
Dec 2018	41	8	3
Jan 2019	17	2	2
Feb 2019	16	1	1
Mar 2019	12	4	0
Apr 2019	31	8	9
May 2019	18	3	3
Jun 2019	6	2	0
Jul 2019	14	8	6
Aug 2019	10	1	1
Sep 2019	11	0	0
Oct 2019	10	2	2
Nov 2019	17	1	1
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Jan 2020	18	2	1
Feb 2020	20	2	5
Mar 2020	140	9	6
Apr 2020	24	5	7
May 2020	15	1	0
Jun 2020	8	3	5
Jul 2020	8	1	1
Aug 2020	15	1	13
Sep 2020	18	3	2
Oct 2020	16	1	1
Nov 2020	22	1	0
Dec 2020	31	2	1
Jan 2021	37	5	0
Feb 2021	14	5	0
Mar 2021	10	2	1
Apr 2021	9	3	1