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Research ArticleArticle

Influence of Microsomal Concentration on Apparent Intrinsic Clearance: Implications for Scaling in Vitro Data

J. Cory Kalvass, David A. Tess, Craig Giragossian, Michael C. Linhares and Tristan S. Maurer
Drug Metabolism and Disposition October 2001, 29 (10) 1332-1336;

Article Information

vol. 29 no. 10 1332-1336
PubMed 
11560877
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 4, 2001
  • Accepted July 19, 2001
  • Published online October 1, 2001.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. J. Cory Kalvass,
  2. David A. Tess,
  3. Craig Giragossian,
  4. Michael C. Linhares and
  5. Tristan S. Maurer
  1. Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development Groton, Connecticut
  1. Tristan S. Maurer, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research, Inc., Eastern Point Road, Groton, CT 06340. E-mail:tristan_s_maurer{at}groton.pfizer.com
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Research ArticleArticle

Influence of Microsomal Concentration on Apparent Intrinsic Clearance: Implications for Scaling in Vitro Data

J. Cory Kalvass, David A. Tess, Craig Giragossian, Michael C. Linhares and Tristan S. Maurer
Drug Metabolism and Disposition October 1, 2001, 29 (10) 1332-1336;
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