Table of Contents

Articles

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  Importance of Amine pK _a and Distribution Coefficient in the Metabolism of Fluorinated Propranolol Derivatives. Preparation, Identification of Metabolite Regioisomers, and Metabolism by CYP2D6

  Alana L. Upthagrove and Wendel L. Nelson

  Drug Metabolism and Disposition November 2001, 29 (11) 1377-1388;
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  Importance of Amine p K _a and Distribution Coefficient in the Metabolism of Fluorinated Propranolol Analogs: Metabolism by CYP1A2

  Alana L. Upthagrove and Wendel L. Nelson

  Drug Metabolism and Disposition November 2001, 29 (11) 1389-1395;
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  Differential Metabolism of 1,1-Dichloroethylene in Livers of A/J, CD-1, and C57BL/6 Mice

  Poh-Gek Forkert and Stephanie M. Boyd

  Drug Metabolism and Disposition November 2001, 29 (11) 1396-1402;
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  Pharmacokinetics and Metabolism of a Cysteinyl Leukotriene-1 Receptor Antagonist from the Heterocyclic Chromanol Series in Rats: In Vitro-In Vivo Correlation, Gender-Related Differences, Isoform Identification, and Comparison with Metabolism in Human Hepatic Tissue

  Alexander V. Kuperman, Amit S. Kalgutkar, Anthony Marfat, Robert J. Chambers and Theodore E. Liston

  Drug Metabolism and Disposition November 2001, 29 (11) 1403-1409;
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  Monoclonal Antibodies Specific and Inhibitory to Human Cytochromes P450 2C8, 2C9, and 2C19

  Kristopher W. Krausz, Inna Goldfarb, Jeroen T. M. Buters, Tian J. Yang, Frank J. Gonzalez and Harry V. Gelboin

  Drug Metabolism and Disposition November 2001, 29 (11) 1410-1423;
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  Absorption, Distribution, Metabolism, and Excretion Considerations in Selection of Orally Active Indole-Containing Endothelin Antagonist

  Donald K. Walker, Kevin N. Dack, Roger P. Dickinson, Katherine S. Fenner, Kim James, David J. Rawson and Dennis A. Smith

  Drug Metabolism and Disposition November 2001, 29 (11) 1424-1431;
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  Caffeic Acid, Chlorogenic Acid, and Dihydrocaffeic Acid Metabolism: Glutathione Conjugate Formation

  Majid Y. Moridani, Hugh Scobie, Akram Jamshidzadeh, Par Salehi and Peter J. O'Brien

  Drug Metabolism and Disposition November 2001, 29 (11) 1432-1439;
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  Identification of New Derivatives of Sinigrin and Glucotropaeolin Produced by the Human Digestive Microflora Using ¹H NMR Spectroscopy Analysis of in Vitro Incubations

  Bruno Combourieu, Lila Elfoul, Anne-Marie Delort and Sylvie Rabot

  Drug Metabolism and Disposition November 2001, 29 (11) 1440-1445;
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  Induction of CYP3A4 by 1α,25-Dihydroxyvitamin D₃ Is Human Cell Line-Specific and Is Unlikely to Involve Pregnane X Receptor

  Phyllissa Schmiedlin-Ren, Kenneth E. Thummel, Jeannine M. Fisher, Mary F. Paine and Paul B. Watkins

  Drug Metabolism and Disposition November 2001, 29 (11) 1446-1453;
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  Natural Protein Variants of Pregnane X Receptor with Altered Transactivation Activity Toward CYP3A4

  Elisabeth Hustert, Arne Zibat, Elena Presecan-Siedel, Regina Eiselt, Romy Mueller, Christine Fuß, Ilka Brehm, Ulrich Brinkmann, Michel Eichelbaum, Leszek Wojnowski and Oliver Burk

  Drug Metabolism and Disposition November 2001, 29 (11) 1454-1459;
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  Blood Thiols Following Amifostine and Mesna Infusions, a Pediatric Oncology Group Study

  Abdul-Kader Souid, Robert C. Fahey, Mehmet K. Aktas, Omer A. Sayin, Sara Karjoo, Gerald L. Newton, Peter D. Sadowitz, Ronald L. Dubowy and Mark L. Bernstein

  Drug Metabolism and Disposition November 2001, 29 (11) 1460-1466;
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  Coordinate Regulation of Xenobiotic and Bile Acid Homeostasis by Pregnane X Receptor

  Jeff Staudinger, Yaping Liu, Ajay Madan, Sultan Habeebu and Curtis D. Klaassen

  Drug Metabolism and Disposition November 2001, 29 (11) 1467-1472;
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  Testosterone, 7-Benzyloxyquinoline, and 7-Benzyloxy-4-trifluoromethyl-coumarin Bind to Different Domains within the Active Site of Cytochrome P450 3A4

  Ping Lu, Yuh Lin, A. David Rodrigues, Thomas H. Rushmore, Thomas A. Baillie and Magang Shou

  Drug Metabolism and Disposition November 2001, 29 (11) 1473-1479;
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  CYP2B6 and CYP2C19 as the Major Enzymes Responsible for the Metabolism of Selegiline, a Drug Used in the Treatment of Parkinson's Disease, as Revealed from Experiments with Recombinant Enzymes

  Mats Hidestrand, Mikael Oscarson, Jarmo S. Salonen, Leena Nyman, Olavi Pelkonen, Miia Turpeinen and Magnus Ingelman-Sundberg

  Drug Metabolism and Disposition November 2001, 29 (11) 1480-1484;
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  Oxidation Mechanism of 7-Hydroxy-Δ⁸-tetrahydrocannabinol and 8-Hydroxy-Δ⁹-tetrahydrocannabinol to the Corresponding Ketones by CYP3A11

  Tamihide Matsunaga, Hiroyuki Tanaka, Shinsuke Higuchi, Kinya Shibayama, Nobuyuki Kishi, Kazuhito Watanabe and Ikuo Yamamoto

  Drug Metabolism and Disposition November 2001, 29 (11) 1485-1491;
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  Pharmacokinetics and Metabolism of Hydroxytyrosol, a Natural Antioxidant from Olive Oil

  Stefania D'Angelo, Caterina Manna, Valentina Migliardi, Orazio Mazzoni, Patrizia Morrica, Giovanni Capasso, Gabriele Pontoni, Patrizia Galletti and Vincenzo Zappia

  Drug Metabolism and Disposition November 2001, 29 (11) 1492-1498;
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  Use of a Reporter Gene Assay to Predict and Rank the Potency and Efficacy of CYP3A4 Inducers

  Wafaa El-Sankary, G. Gordon Gibson, Andy Ayrton and Nick Plant

  Drug Metabolism and Disposition November 2001, 29 (11) 1499-1504;
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  A New Metabolite of Irinotecan in Which Formation Is Mediated by Human Hepatic Cytochrome P-450 3a4

  Kimie Sai, Naoko Kaniwa, Shogo Ozawa and Jun-ichi Sawada

  Drug Metabolism and Disposition November 2001, 29 (11) 1505-1513;
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  Comparative Contribution to Dextromethorphan Metabolism by Cytochrome P450 Isoforms in Vitro: Can Dextromethorphan Be Used as a Dual Probe for Both CYP2D6 and CYP3A Activities?

  Aiming Yu and Robert L. Haining

  Drug Metabolism and Disposition November 2001, 29 (11) 1514-1520;