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Drug Metabolism & Disposition

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Table of Contents

November 01, 2001; Volume 29,Issue 11

Short Communications

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    Gemfibrozil Is a Potent Inhibitor of Human Cytochrome P450 2C9
    Xia Wen, Jun-Sheng Wang, Janne T. Backman, Kari T. Kivistö and Pertti J. Neuvonen
    Drug Metabolism and Disposition November 2001, 29 (11) 1359-1361;
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    Characterization of Dextromethorphan O- andN-Demethylation Catalyzed by Highly Purified Recombinant Human CYP2D6
    Aiming Yu, Haijun Dong, Dieter Lang and Robert L. Haining
    Drug Metabolism and Disposition November 2001, 29 (11) 1362-1365;

Symposium Report

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    Cytochromes P450 and Flavin Monooxygenases—Targets and Sources of Nitric Oxide
    Edward T. Morgan, Volker Ullrich, Andreas Daiber, Patrick Schmidt, Naoki Takaya, Hirofumi Shoun, John C. McGiff, Adebayo Oyekan, Craig J. Hanke, William B. Campbell, Chang-Shin Park, Ju-Seop Kang, Hyeon-Gyu Yi, Young-Nam Cha, Daniel Mansuy and Jean-Luc Boucher
    Drug Metabolism and Disposition November 2001, 29 (11) 1366-1376;

Articles

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    Importance of Amine pK a and Distribution Coefficient in the Metabolism of Fluorinated Propranolol Derivatives. Preparation, Identification of Metabolite Regioisomers, and Metabolism by CYP2D6
    Alana L. Upthagrove and Wendel L. Nelson
    Drug Metabolism and Disposition November 2001, 29 (11) 1377-1388;
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    Importance of Amine p K a and Distribution Coefficient in the Metabolism of Fluorinated Propranolol Analogs: Metabolism by CYP1A2
    Alana L. Upthagrove and Wendel L. Nelson
    Drug Metabolism and Disposition November 2001, 29 (11) 1389-1395;
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    Differential Metabolism of 1,1-Dichloroethylene in Livers of A/J, CD-1, and C57BL/6 Mice
    Poh-Gek Forkert and Stephanie M. Boyd
    Drug Metabolism and Disposition November 2001, 29 (11) 1396-1402;
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    Pharmacokinetics and Metabolism of a Cysteinyl Leukotriene-1 Receptor Antagonist from the Heterocyclic Chromanol Series in Rats: In Vitro-In Vivo Correlation, Gender-Related Differences, Isoform Identification, and Comparison with Metabolism in Human Hepatic Tissue
    Alexander V. Kuperman, Amit S. Kalgutkar, Anthony Marfat, Robert J. Chambers and Theodore E. Liston
    Drug Metabolism and Disposition November 2001, 29 (11) 1403-1409;
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    Monoclonal Antibodies Specific and Inhibitory to Human Cytochromes P450 2C8, 2C9, and 2C19
    Kristopher W. Krausz, Inna Goldfarb, Jeroen T. M. Buters, Tian J. Yang, Frank J. Gonzalez and Harry V. Gelboin
    Drug Metabolism and Disposition November 2001, 29 (11) 1410-1423;
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    Absorption, Distribution, Metabolism, and Excretion Considerations in Selection of Orally Active Indole-Containing Endothelin Antagonist
    Donald K. Walker, Kevin N. Dack, Roger P. Dickinson, Katherine S. Fenner, Kim James, David J. Rawson and Dennis A. Smith
    Drug Metabolism and Disposition November 2001, 29 (11) 1424-1431;
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    Caffeic Acid, Chlorogenic Acid, and Dihydrocaffeic Acid Metabolism: Glutathione Conjugate Formation
    Majid Y. Moridani, Hugh Scobie, Akram Jamshidzadeh, Par Salehi and Peter J. O'Brien
    Drug Metabolism and Disposition November 2001, 29 (11) 1432-1439;
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    Identification of New Derivatives of Sinigrin and Glucotropaeolin Produced by the Human Digestive Microflora Using 1H NMR Spectroscopy Analysis of in Vitro Incubations
    Bruno Combourieu, Lila Elfoul, Anne-Marie Delort and Sylvie Rabot
    Drug Metabolism and Disposition November 2001, 29 (11) 1440-1445;
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    Induction of CYP3A4 by 1α,25-Dihydroxyvitamin D3 Is Human Cell Line-Specific and Is Unlikely to Involve Pregnane X Receptor
    Phyllissa Schmiedlin-Ren, Kenneth E. Thummel, Jeannine M. Fisher, Mary F. Paine and Paul B. Watkins
    Drug Metabolism and Disposition November 2001, 29 (11) 1446-1453;
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    Natural Protein Variants of Pregnane X Receptor with Altered Transactivation Activity Toward CYP3A4
    Elisabeth Hustert, Arne Zibat, Elena Presecan-Siedel, Regina Eiselt, Romy Mueller, Christine Fuß, Ilka Brehm, Ulrich Brinkmann, Michel Eichelbaum, Leszek Wojnowski and Oliver Burk
    Drug Metabolism and Disposition November 2001, 29 (11) 1454-1459;
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    Blood Thiols Following Amifostine and Mesna Infusions, a Pediatric Oncology Group Study
    Abdul-Kader Souid, Robert C. Fahey, Mehmet K. Aktas, Omer A. Sayin, Sara Karjoo, Gerald L. Newton, Peter D. Sadowitz, Ronald L. Dubowy and Mark L. Bernstein
    Drug Metabolism and Disposition November 2001, 29 (11) 1460-1466;
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    Coordinate Regulation of Xenobiotic and Bile Acid Homeostasis by Pregnane X Receptor
    Jeff Staudinger, Yaping Liu, Ajay Madan, Sultan Habeebu and Curtis D. Klaassen
    Drug Metabolism and Disposition November 2001, 29 (11) 1467-1472;
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    Testosterone, 7-Benzyloxyquinoline, and 7-Benzyloxy-4-trifluoromethyl-coumarin Bind to Different Domains within the Active Site of Cytochrome P450 3A4
    Ping Lu, Yuh Lin, A. David Rodrigues, Thomas H. Rushmore, Thomas A. Baillie and Magang Shou
    Drug Metabolism and Disposition November 2001, 29 (11) 1473-1479;
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    CYP2B6 and CYP2C19 as the Major Enzymes Responsible for the Metabolism of Selegiline, a Drug Used in the Treatment of Parkinson's Disease, as Revealed from Experiments with Recombinant Enzymes
    Mats Hidestrand, Mikael Oscarson, Jarmo S. Salonen, Leena Nyman, Olavi Pelkonen, Miia Turpeinen and Magnus Ingelman-Sundberg
    Drug Metabolism and Disposition November 2001, 29 (11) 1480-1484;
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    Oxidation Mechanism of 7-Hydroxy-Δ8-tetrahydrocannabinol and 8-Hydroxy-Δ9-tetrahydrocannabinol to the Corresponding Ketones by CYP3A11
    Tamihide Matsunaga, Hiroyuki Tanaka, Shinsuke Higuchi, Kinya Shibayama, Nobuyuki Kishi, Kazuhito Watanabe and Ikuo Yamamoto
    Drug Metabolism and Disposition November 2001, 29 (11) 1485-1491;
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    Pharmacokinetics and Metabolism of Hydroxytyrosol, a Natural Antioxidant from Olive Oil
    Stefania D'Angelo, Caterina Manna, Valentina Migliardi, Orazio Mazzoni, Patrizia Morrica, Giovanni Capasso, Gabriele Pontoni, Patrizia Galletti and Vincenzo Zappia
    Drug Metabolism and Disposition November 2001, 29 (11) 1492-1498;
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    Use of a Reporter Gene Assay to Predict and Rank the Potency and Efficacy of CYP3A4 Inducers
    Wafaa El-Sankary, G. Gordon Gibson, Andy Ayrton and Nick Plant
    Drug Metabolism and Disposition November 2001, 29 (11) 1499-1504;
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    A New Metabolite of Irinotecan in Which Formation Is Mediated by Human Hepatic Cytochrome P-450 3a4
    Kimie Sai, Naoko Kaniwa, Shogo Ozawa and Jun-ichi Sawada
    Drug Metabolism and Disposition November 2001, 29 (11) 1505-1513;
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    Comparative Contribution to Dextromethorphan Metabolism by Cytochrome P450 Isoforms in Vitro: Can Dextromethorphan Be Used as a Dual Probe for Both CYP2D6 and CYP3A Activities?
    Aiming Yu and Robert L. Haining
    Drug Metabolism and Disposition November 2001, 29 (11) 1514-1520;
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In this issue

Drug Metabolism and Disposition: 29 (11)
Drug Metabolism and Disposition
Vol. 29, Issue 11
1 Nov 2001
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