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Meeting ReportSymposium Report

Cytochromes P450 and Flavin Monooxygenases—Targets and Sources of Nitric Oxide

Edward T. Morgan, Volker Ullrich, Andreas Daiber, Patrick Schmidt, Naoki Takaya, Hirofumi Shoun, John C. McGiff, Adebayo Oyekan, Craig J. Hanke, William B. Campbell, Chang-Shin Park, Ju-Seop Kang, Hyeon-Gyu Yi, Young-Nam Cha, Daniel Mansuy and Jean-Luc Boucher
Drug Metabolism and Disposition November 2001, 29 (11) 1366-1376;
Edward T. Morgan
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Volker Ullrich
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Andreas Daiber
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Patrick Schmidt
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Naoki Takaya
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Hirofumi Shoun
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John C. McGiff
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Adebayo Oyekan
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Craig J. Hanke
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William B. Campbell
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Chang-Shin Park
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Ju-Seop Kang
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Hyeon-Gyu Yi
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Young-Nam Cha
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Daniel Mansuy
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Jean-Luc Boucher
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Article Information

vol. 29 no. 11 1366-1376
PubMed 
11602511

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 21, 2001
  • Accepted August 6, 2001
  • Published online November 1, 2001.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Edward T. Morgan1,
  2. Volker Ullrich2,
  3. Andreas Daiber2,
  4. Patrick Schmidt2,
  5. Naoki Takaya3,
  6. Hirofumi Shoun4,
  7. John C. McGiff5,
  8. Adebayo Oyekan6,
  9. Craig J. Hanke7,
  10. William B. Campbell7,
  11. Chang-Shin Park8,
  12. Ju-Seop Kang9,
  13. Hyeon-Gyu Yi8,
  14. Young-Nam Cha8,
  15. Daniel Mansuy10 and
  16. Jean-Luc Boucher10
  1. 1Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia (E.T.M.); 2Department of Biology, University of Konstanz, Konstanz, Germany (V.U., A.D., P.S.); 3Institute of Applied Biochemistry, University of Tsukuba, Ibaraki, Japan (N.T.); 4Department of Biotechnology, University of Tokyo, Tokyo, Japan (H.S.); 5Department of Pharmacology, New York Medical College, Valhalla, New York (J.C.McG.); 6Center for Cardiovascular Diseases, Texas Southern University, Houston, Texas (A.O.); 7Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin (C.J.H., W.B.C); 8Department of Pharmacology and Toxicology, Inha University, Incon, Korea (C.S.P., H.G.Y., Y.N.C.); 9Department of Pharmacology, Hanyang University, Seoul, Korea (J.S.K.); and 10UMR 8601 Centre National de la Recherche Scientifique, University of Paris V, Paris, France (D.M., J.-L. B.).
  1. Dr. Edward T. Morgan, Department of Pharmacology, Emory University, Atlanta, GA 30322. E-mail: etmorga{at}emory.edu
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Drug Metabolism and Disposition: 29 (11)
Drug Metabolism and Disposition
Vol. 29, Issue 11
1 Nov 2001
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Meeting ReportSymposium Report

Cytochromes P450 and Flavin Monooxygenases—Targets and Sources of Nitric Oxide

Edward T. Morgan, Volker Ullrich, Andreas Daiber, Patrick Schmidt, Naoki Takaya, Hirofumi Shoun, John C. McGiff, Adebayo Oyekan, Craig J. Hanke, William B. Campbell, Chang-Shin Park, Ju-Seop Kang, Hyeon-Gyu Yi, Young-Nam Cha, Daniel Mansuy and Jean-Luc Boucher
Drug Metabolism and Disposition November 1, 2001, 29 (11) 1366-1376;

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Meeting ReportSymposium Report

Cytochromes P450 and Flavin Monooxygenases—Targets and Sources of Nitric Oxide

Edward T. Morgan, Volker Ullrich, Andreas Daiber, Patrick Schmidt, Naoki Takaya, Hirofumi Shoun, John C. McGiff, Adebayo Oyekan, Craig J. Hanke, William B. Campbell, Chang-Shin Park, Ju-Seop Kang, Hyeon-Gyu Yi, Young-Nam Cha, Daniel Mansuy and Jean-Luc Boucher
Drug Metabolism and Disposition November 1, 2001, 29 (11) 1366-1376;
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  • Article
    • Abstract
    • Isoform-Selective Role of NO in Hepatic Cytochrome P450 Down-Regulation (E.T.M.)
    • Reactions of P450 Proteins with Peroxynitrite (V.U., A.D., P.S., T.N., and H.S.)
    • NO Exerts a Tonic Inhibitory Effect on 20-HETE Formation: Renal Functional Implications (J.C.McG. and A.O.)
    • Nitric Oxide Inhibits Steroid Hormone Synthesis in Adrenal Zona Glomerulosa Cells (C.J.H. and W.B.C.)
    • Overproduction of Nitric Oxide Causes Reduction of Hepatic Flavin-Containing Monooxygenase (FMO) Activity and Trimethylaminuria in Patients with Chronic Viral Hepatitis (C.S.P, J.S.K., H.G.Y., and Y.N.C.)
    • Formation of Nitric Oxide by Cytochromes P450: Comparison with NO Synthases (D.M. and J.-L. B.)
    • Acknowledgments
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    • References
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  • Physiological Regulation of Drug Transport and Metabolism
  • P450 System Protein-Protein and Protein-Lipid Interactions
  • Interindividual Variability in P450s
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