Use of a Reporter Gene Assay to Predict and Rank the Potency and Efficacy of CYP3A4 Inducers

Dr. Nick Plant, Molecular Toxicology, School of Biological Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK. E-mail: n.plant{at}surrey.ac.uk

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Article usage: October 2001 to June 2022

	Abstract	Full	Pdf
Oct 2001	89	143	269
Nov 2001	43	68	143
Dec 2001	11	42	63
Jan 2002	9	38	55
Feb 2002	4	33	36
Mar 2002	10	35	34
Apr 2002	9	39	28
May 2002	9	33	24
Jun 2002	6	32	22
Jul 2002	12	31	18
Aug 2002	5	18	16
Sep 2002	5	32	26
Oct 2002	8	24	20
Nov 2002	4	29	24
Dec 2002	4	15	18
Jan 2003	2	23	32
Feb 2003	2	21	20
Mar 2003	6	31	34
Apr 2003	1	13	11
May 2003	4	7	17
Jun 2003	1	13	22
Jul 2003	11	44	19
Aug 2003	10	29	25
Sep 2003	10	28	6
Oct 2003	17	31	10
Nov 2003	11	35	20
Dec 2003	7	49	8
Jan 2004	16	45	18
Feb 2004	8	26	10
Mar 2004	9	30	19
Apr 2004	5	20	17
May 2004	11	26	19
Jun 2004	14	29	8
Jul 2004	20	33	16
Aug 2004	18	27	9
Sep 2004	20	33	8
Oct 2004	23	49	12
Nov 2004	21	59	25
Dec 2004	21	47	18
Jan 2005	26	56	18
Feb 2005	20	50	17
Mar 2005	14	37	18
Apr 2005	5	44	20
May 2005	5	30	10
Jun 2005	6	20	12
Jul 2005	14	30	13
Aug 2005	5	30	17
Sep 2005	5	26	15
Oct 2005	8	20	17
Nov 2005	3	25	13
Dec 2005	6	27	10
Jan 2006	6	17	10
Feb 2006	6	24	8
Mar 2006	7	39	15
Apr 2006	2	27	11
May 2006	8	25	11
Jun 2006	5	23	13
Jul 2006	6	22	10
Aug 2006	13	9	9
Sep 2006	6	12	14
Oct 2006	10	21	25
Nov 2006	3	35	20
Dec 2006	4	22	12
Jan 2007	8	26	32
Feb 2007	8	22	20
Mar 2007	11	25	15
Apr 2007	7	33	22
May 2007	7	36	19
Jun 2007	8	34	15
Jul 2007	4	29	20
Aug 2007	6	22	14
Sep 2007	9	24	13
Oct 2007	15	35	12
Nov 2007	6	26	21
Dec 2007	4	12	22
Jan 2008	4	16	15
Feb 2008	9	13	9
Mar 2008	10	12	11
Apr 2008	7	10	15
May 2008	8	17	11
Jun 2008	13	20	12
Jul 2008	31	36	18
Aug 2008	22	24	10
Sep 2008	6	12	7
Oct 2008	14	15	12
Nov 2008	21	11	14
Dec 2008	8	10	7
Jan 2009	6	11	9
Feb 2009	11	17	10
Mar 2009	22	16	8
Apr 2009	5	10	9
May 2009	8	9	11
Jun 2009	6	12	5
Jul 2009	4	10	7
Aug 2009	14	12	7
Sep 2009	14	10	8
Oct 2009	21	13	12
Nov 2009	22	14	12
Dec 2009	16	12	6
Jan 2010	15	6	11
Feb 2010	11	4	13
Mar 2010	28	6	11
Apr 2010	22	18	13
May 2010	22	13	12
Jun 2010	15	10	8
Jul 2010	42	22	18
Aug 2010	16	17	5
Sep 2010	17	30	19
Oct 2010	19	20	17
Nov 2010	8	15	11
Dec 2010	10	28	15
Jan 2011	18	18	10
Feb 2011	19	13	11
Mar 2011	25	31	13
Apr 2011	16	21	13
May 2011	29	21	13
Jun 2011	15	21	7
Jul 2011	31	17	10
Aug 2011	17	7	15
Sep 2011	28	9	11
Oct 2011	39	12	14
Nov 2011	33	16	15
Dec 2011	21	10	8
Jan 2012	24	11	9
Feb 2012	28	8	10
Mar 2012	38	18	19
Apr 2012	16	11	10
May 2012	38	16	20
Jun 2012	25	23	19
Jul 2012	39	20	16
Aug 2012	25	22	18
Sep 2012	28	12	31
Oct 2012	25	10	21
Nov 2012	26	13	20
Dec 2012	29	11	13
Jan 2013	37	24	22
Feb 2013	22	12	10
Mar 2013	29	14	18
Apr 2013	41	24	26
May 2013	29	13	17
Jun 2013	16	9	11
Jul 2013	21	9	12
Aug 2013	15	3	9
Sep 2013	26	4	6
Oct 2013	20	3	16
Nov 2013	13	2	11
Dec 2013	14	5	9
Jan 2014	23	5	9
Feb 2014	22	2	5
Mar 2014	19	2	3
Apr 2014	30	10	12
May 2014	41	4	14
Jun 2014	34	1	7
Jul 2014	26	8	9
Aug 2014	14	14	8
Sep 2014	9	14	6
Oct 2014	33	16	10
Nov 2014	12	13	5
Dec 2014	20	11	7
Jan 2015	16	9	7
Feb 2015	8	10	4
Mar 2015	29	3	8
Apr 2015	22	11	5
May 2015	25	1	0
Jun 2015	18	17	6
Jul 2015	17	7	12
Aug 2015	12	7	4
Sep 2015	10	9	3
Oct 2015	16	3	2
Nov 2015	16	8	12
Dec 2015	20	8	4
Jan 2016	29	20	11
Feb 2016	6	12	2
Mar 2016	15	4	7
Apr 2016	10	9	4
May 2016	16	8	8
Jun 2016	18	4	16
Jul 2016	12	6	11
Aug 2016	9	11	10
Sep 2016	9	8	7
Oct 2016	3	14	5
Nov 2016	9	6	8
Dec 2016	3	4	9
Jan 2017	4	21	9
Feb 2017	1	8	2
Mar 2017	4	27	11
Apr 2017	4	12	1
May 2017	1	16	7
Jun 2017	1	8	2
Jul 2017	2	7	7
Aug 2017	0	13	3
Sep 2017	1	20	9
Oct 2017	1	21	2
Nov 2017	2	46	2
Dec 2017	1	13	0
Jan 2018	2	19	3
Feb 2018	2	29	9
Mar 2018	6	21	10
Apr 2018	2	19	6
May 2018	2	32	8
Jun 2018	4	18	12
Jul 2018	5	18	13
Aug 2018	2	8	5
Sep 2018	0	11	4
Oct 2018	6	22	13
Nov 2018	2	28	12
Dec 2018	14	19	3
Jan 2019	14	2	2
Feb 2019	20	0	1
Mar 2019	34	3	0
Apr 2019	23	2	2
May 2019	13	0	1
Jun 2019	13	1	3
Jul 2019	13	0	0
Aug 2019	8	2	0
Sep 2019	16	3	0
Oct 2019	15	1	1
Nov 2019	20	0	2
Dec 2019	20	8	2
Jan 2020	15	3	0
Feb 2020	27	1	1
Mar 2020	12	6	2
Apr 2020	21	3	2
May 2020	4	1	1
Jun 2020	17	0	0
Jul 2020	5	0	0
Aug 2020	9	1	2
Sep 2020	8	3	0
Oct 2020	15	0	0
Nov 2020	15	0	0
Dec 2020	19	2	0
Jan 2021	17	20	2
Feb 2021	15	22	1
Mar 2021	10	2	2
Apr 2021	13	5	2
May 2021	18	4	0
Jun 2021	16	11	1
Jul 2021	13	5	0
Aug 2021	12	12	0
Sep 2021	10	7	1
Oct 2021	18	3	0
Nov 2021	21	4	0
Dec 2021	17	5	1
Jan 2022	10	3	0
Feb 2022	24	2	2
Mar 2022	21	3	1
Apr 2022	30	4	1
May 2022	4	4	1
Jun 2022	15	2	1