Table of Contents

Articles

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  Evidence Supporting the Interaction of CYP2B4 and CYP1A2 in Microsomal Preparations

  George F. Cawley, Shuxin Zhang, Russell W. Kelley and Wayne L. Backes

  Drug Metabolism and Disposition December 2001, 29 (12) 1529-1534;
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  In Vivo Perturbation of Rat Hepatocyte Canalicular Membrane Function by Diclofenac

  Benedetta C. Sallustio and Felicity L. Holbrook

  Drug Metabolism and Disposition December 2001, 29 (12) 1535-1538;
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  Absorption of Benzoic Acid in Segmental Regions of the Vascularly Perfused Rat Small Intestine Preparation

  Diem Cong, Angela K. Y. Fong, Ronita Lee and K. Sandy Pang

  Drug Metabolism and Disposition December 2001, 29 (12) 1539-1547;
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  Cytochrome P450 Involvement in the Biotransformation of Cisapride and Racemic Norcisapride in Vitro: Differential Activity of Individual Human CYP3A Isoforms

  Robin E. Pearce, R. Russell Gotschall, Gregory L. Kearns and J. Steven Leeder

  Drug Metabolism and Disposition December 2001, 29 (12) 1548-1554;
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  Characterization of the Selectivity and Mechanism of Cytochrome P450 Inhibition by Dimethyl-4,4′-dimethoxy-5,6,5′,6′-
  dimethylenedioxybiphenyl-2,2′-dicarboxylate

  Ji-Yeon Kim, Minsun Baek, Sooyong Lee, Sung-Ok Kim, Mi-Sook Dong, Bok-Ryang Kim and Dong-Hyun Kim

  Drug Metabolism and Disposition December 2001, 29 (12) 1555-1560;
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  The Effect of Troglitazone Biliary Excretion on Metabolite Distribution and Cholestasis in Transporter-Deficient Rats

  Vsevolod E. Kostrubsky, Mary Vore, Erick Kindt, James Burliegh, Karen Rogers, Gregory Peter, Douglas Altrogge and Michael W. Sinz

  Drug Metabolism and Disposition December 2001, 29 (12) 1561-1566;
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  Metabolism of (R)-(+)-Pulegone in F344 Rats

  Ling-Jen Chen, Edward H. Lebetkin and Leo T. Burka

  Drug Metabolism and Disposition December 2001, 29 (12) 1567-1577;
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  Pharmacokinetics and Metabolism of a Ras Farnesyl Transferase Inhibitor in Rats and Dogs: In Vitro-In Vivo Correlation

  Rominder Singh, I-Wu Chen, Lixia Jin, Maria V. Silva, Byron H. Arison, Jiunn H. Lin and Bradley K. Wong

  Drug Metabolism and Disposition December 2001, 29 (12) 1578-1587;
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  Boron Neutron Capture Therapy of Brain Tumors: Investigation of Urinary Metabolites and Oxidation Products of Sodium Borocaptate by Electrospray Ionization Mass Spectrometry

  Christopher R. Gibson, Alfred E. Staubus, Rolf F. Barth, Weilian Yang, Nan M. Kleinholz, R. Benjamin Jones, Kari Green-Church, Werner Tjarks and Albert H. Soloway

  Drug Metabolism and Disposition December 2001, 29 (12) 1588-1598;
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  Mechanism of Cytochrome P4503A4- and 2D6-Catalyzed Dehydrogenation of Ezlopitant as Probed with Isotope Effects Using Five Deuterated Analogs

  R. Scott Obach

  Drug Metabolism and Disposition December 2001, 29 (12) 1599-1607;
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  Bioactivation of Diclofenac via Benzoquinone Imine Intermediates—Identification of Urinary Mercapturic Acid Derivatives in Rats and Humans

  Grace K. Poon, Qing Chen, Yohannes Teffera, Jason S. Ngui, Patrick R. Griffin, Mathew P. Braun, George A. Doss, Christopher Freeden, Ralph A. Stearns, David C. Evans, Thomas A. Baillie and Wei Tang

  Drug Metabolism and Disposition December 2001, 29 (12) 1608-1613;
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  Mechanistic Studies on the Reversible Metabolism of Rofecoxib to 5-Hydroxyrofecoxib in the Rat: Evidence for Transient Ring Opening of a Substituted 2-Furanone Derivative Using Stable Isotope-Labeling Techniques.

  Thomas A. Baillie, Rita A. Halpin, Bogdan K. Matuszewski, Leslie A. Geer, Cynthia M. Chavez-Eng, Dennis Dean, Matthew Braun, George Doss, Allen Jones, Tina Marks, David Melillo and Kamlesh P. Vyas

  Drug Metabolism and Disposition December 2001, 29 (12) 1614-1628;
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  Population Distribution of Human Flavin-Containing Monooxygenase Form 3: Gene Polymorphisms

  John R. Cashman, Jun Zhang, James Leushner and Andreas Braun

  Drug Metabolism and Disposition December 2001, 29 (12) 1629-1637;
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  In Vitro Characterization of the Metabolism of Haloperidol Using Recombinant Cytochrome P450 Enzymes and Human Liver Microsomes

  Jim Fang, Gordon McKay, Jiuxue Song, Alfread Remillrd, Xinmin Li and Kamal Midha

  Drug Metabolism and Disposition December 2001, 29 (12) 1638-1643;
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  Multisite Kinetic Models for CYP3A4: Simultaneous Activation and Inhibition of Diazepam and Testosterone Metabolism

  Kathryn E. Kenworthy, Stephen E. Clarke, Julie Andrews and J. Brian Houston

  Drug Metabolism and Disposition December 2001, 29 (12) 1644-1651;