Formation of the Quaternary Ammonium-Linked Glucuronide of Nicotine in Human Liver Microsomes: Identification and Stereoselectivity in the Kinetics

Omar Ghosheh; Sarvesh C. Vashishtha; Edward M. Hawes

Article Information

vol. 29 no. 12 1525-1528

PubMed

11717169

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0090-9556

Online ISSN

1521-009X

History

Received July 13, 2001
Accepted September 12, 2001
Published online December 1, 2001.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

Omar Ghosheh,
Sarvesh C. Vashishtha2 and
Edward M. Hawes

Drug Metabolism and Drug Disposition
Group,
College of Pharmacy and Nutrition,
University of Saskatchewan,
Saskatoon, Saskatchewan, Canada

Edward M. Hawes, Drug Metabolism and Drug Disposition Group, College of Pharmacy and Nutrition, 110 Science Place, University of Saskatchewan, Saskatoon, SK, S7N 5C9, Canada. E-mail: hawes{at}duke.usask.ca

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