Table of Contents

Articles

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  A Flow Cell Assay for Evaluation of Whole Cell Drug Efflux Kinetics: Analysis of Paclitaxel Efflux in CCRF-CEM Leukemia Cells Overexpressing P-Glycoprotein

  James T. Lin, Rashmi Sharma, James J. Grady and Sanjay Awasthi

  Drug Metabolism and Disposition February 2001, 29 (2) 103-110;
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  Epidermal Growth Factor Regulation of Female-Dependent CYP2A1 and CYP2C12 in Primary Rat Hepatocyte Culture

  Martha C. Garcia, Chellappagounder Thangavel and Bernard H. Shapiro

  Drug Metabolism and Disposition February 2001, 29 (2) 111-120;
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  Evidence for Significant Differences in Microsomal Drug Glucuronidation by Canine and Human Liver and Kidney

  Matthew G. Soars, Robert J. Riley, Karen A. B. Findlay, Marcus J. Coffey and Brian Burchell

  Drug Metabolism and Disposition February 2001, 29 (2) 121-126;
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  Metabolism of a Disulfiram Metabolite, S-MethylN,N-Diethyldithiocarbamate, by Flavin Monooxygenase in Human Renal Microsomes

  M. Gennett Pike, Dennis C. Mays, David W. Macomber and James J. Lipsky

  Drug Metabolism and Disposition February 2001, 29 (2) 127-132;
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  CYP3A4 Is the Major CYP Isoform Mediating the in Vitro Hydroxylation and Demethylation of Flunitrazepam

  Leah M. Hesse, Karthik Venkatakrishnan, Lisa L. von Moltke, Richard I. Shader and David J. Greenblatt

  Drug Metabolism and Disposition February 2001, 29 (2) 133-140;
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  Effects of Organic Solvents on the Activities of Cytochrome P450 Isoforms, UDP-Dependent Glucuronyl Transferase, and Phenol Sulfotransferase in Human Hepatocytes

  Judy Easterbrook, Chuang Lu, Yumiko Sakai and Albert P. Li

  Drug Metabolism and Disposition February 2001, 29 (2) 141-144;
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  Pharmacokinetic Interaction of Cytochrome P450 3A-Related Compounds with Rhodamine 123, a P-Glycoprotein Substrate, in Rats Pretreated with Dexamethasone

  Ryoko Yumoto, Teruo Murakami, Maki Sanemasa, Reishi Nasu, Junya Nagai and Mikihisa Takano

  Drug Metabolism and Disposition February 2001, 29 (2) 145-151;
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  Metabolism of Amiodarone (Part I): Identification of a New Hydroxylated Metabolite of Amiodarone

  Huy Riem Ha, Laurent Bigler, Martin Binder, Peter Kozlik, Bruno Stieger, Manfred Hesse, Hansruedi R. Altorfer and Ferenc Follath

  Drug Metabolism and Disposition February 2001, 29 (2) 152-158;
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  Application of Rat Hepatocyte Culture to Predict in Vivo Metabolic Auto-Induction: Studies with DFP, a Cyclooxygenase-2 Inhibitor

  Deborah A. Nicoll-Griffith, Jose M. Silva, Nathalie Chauret, Stephen Day, Yves Leblanc, Patrick Roy, James A. Yergey, Rakesh Dixit and Darryl Patrick

  Drug Metabolism and Disposition February 2001, 29 (2) 159-165;
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  Metabolism and Disposition of α-Methylstyrene in Rats

  Kristi S. De Costa, Sherry R. Black, Brian F. Thomas, Jason P. Burgess and James M. Mathews

  Drug Metabolism and Disposition February 2001, 29 (2) 166-171;
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  Human 3′-Phosphoadenosine 5′-Phosphosulfate Synthetase: Radiochemical Enzymatic Assay, Biochemical Properties, and Hepatic Variation

  Zhen-Hua Xu, Thomas C. Wood, Araba A. Adjei and Richard M. Weinshilboum

  Drug Metabolism and Disposition February 2001, 29 (2) 172-178;
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  Stereochemical Aspects of Vinylcyclohexene Bioactivation in Rodent Hepatic Microsomes and Purified Human Cytochrome P450 Enzyme Systems

  Susan M. Fontaine, Eugene A. Mash, Patricia B. Hoyer and I. Glenn Sipes

  Drug Metabolism and Disposition February 2001, 29 (2) 179-184;
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  Methanol Solvent May Cause Increased Apparent Metabolic Instability in in Vitro Assays

  Hequn Yin, Phi Tran, Gerald E. Greenberg and Volker Fischer

  Drug Metabolism and Disposition February 2001, 29 (2) 185-193;
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  Maturational Changes in CYP2D16 Expression and Xenobiotic Metabolism in Adrenal Glands from Male and Female Guinea Pigs

  Bing-Bing Yuan, Ruy Tchao, Jeffrey M. Voigt and Howard D. Colby

  Drug Metabolism and Disposition February 2001, 29 (2) 194-199;
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  Oxidation of 1,8-Cineole, the Monoterpene Cyclic Ether Originated From Eucalyptus Polybractea, by Cytochrome P450 3A Enzymes in Rat and Human Liver Microsomes

  Mitsuo Miyazawa, Masaki Shindo and Tsutomu Shimada

  Drug Metabolism and Disposition February 2001, 29 (2) 200-205;