Table of Contents

Articles

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  In Vitro Inhibition of Cytochrome P450 Enzymes in Human Liver Microsomes by a Potent CYP2A6 inhibitor, trans-2-Phenylcyclopropylamine (Tranylcypromine), and Its Nonamine Analog, Cyclopropylbenzene

  Päivi Taavitsainen, Risto Juvonen and Olavi Pelkonen

  Drug Metabolism and Disposition March 2001, 29 (3) 217-222;
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  In Vitro Biotransformation of Xanthohumol, a Flavonoid from Hops (Humulus lupulus), by Rat Liver Microsomes

  Meltem Yilmazer, Jan F. Stevens, Max L. Deinzer and Donald R. Buhler

  Drug Metabolism and Disposition March 2001, 29 (3) 223-231;
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  Investigation of the in Vitro Metabolism Profile of a Phosphodiesterase-IV Inhibitor, CDP-840: Leading to Structural Optimization

  Chun Li, Nathalie Chauret, Laird A. Trimble, Deborah A. Nicoll-Griffith, Jose M. Silva, Dwight MacDonald, Helene Perrier, James A. Yergey, Ted Parton, Rakki P. Alexander and Graham J. Warrellow

  Drug Metabolism and Disposition March 2001, 29 (3) 232-241;
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  Induction of CYP2C Genes in Human Hepatocytes in Primary Culture

  Sabine Gerbal-Chaloin, Jean-Marc Pascussi, Lydiane Pichard-Garcia, Martine Daujat, Felix Waechter, Jean-Michel Fabre, Nicolas Carrère and Patrick Maurel

  Drug Metabolism and Disposition March 2001, 29 (3) 242-251;
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  Effects of Bacterial Lipopolysaccharide on Phenobarbital-Induced CYP2B Expression in Mice

  Tong Li-Masters and Edward T. Morgan

  Drug Metabolism and Disposition March 2001, 29 (3) 252-257;
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  Involvement of CYP2E1 and Carboxylesterase Enzymes in Vinyl Carbamate Metabolism in Human Lung Microsomes

  Poh-Gek Forkert, Raymond P. Lee and Ken Reid

  Drug Metabolism and Disposition March 2001, 29 (3) 258-263;
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  Glutathione S-Transferase Activity Influences Busulfan Pharmacokinetics in Patients with Beta Thalassemia Major Undergoing Bone Marrow Transplantation

  Balasubramanian Poonkuzhali, Mammen Chandy, Alok Srivastava, David Dennison and Rajagopal Krishnamoorthy

  Drug Metabolism and Disposition March 2001, 29 (3) 264-267;
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  Novel Mutations of CYP3A4 in Chinese

  Kun-Pin Hsieh, Yen-Yu Lin, Ching-Ling Cheng, Ming-Liang Lai, Min-Shung Lin, Jean-Pascal Siest and Jin-Ding Huang

  Drug Metabolism and Disposition March 2001, 29 (3) 268-273;
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  Enzymatic Characterization and Interspecies Difference of Phenol Sulfotransferases, ST1A Forms

  Wataru Honma, Yoshiteru Kamiyama, Kouichi Yoshinari, Hironobu Sasano, Miki Shimada, Kiyoshi Nagata and Yasushi Yamazoe

  Drug Metabolism and Disposition March 2001, 29 (3) 274-281;
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  A Comparison of the Effects of 3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG-CoA) Reductase Inhibitors on the CYP3A4-Dependent Oxidation of Mexazolam in Vitro

  Michi Ishigami, Tomoyo Honda, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito and Yuichi Sugiyama

  Drug Metabolism and Disposition March 2001, 29 (3) 282-288;
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  Characterization of 2-[[4-[[2-(1H-Tetrazol-5-ylmethyl)phenyl]methoxy]phenoxy]methyl] Quinoline N-Glucuronidation by in Vitro and in Vivo Approaches

  Jeffrey C. Stevens, Jessica L. Fayer and Kenneth C. Cassidy

  Drug Metabolism and Disposition March 2001, 29 (3) 289-295;
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  Tissue-Specific Alterations in the 6-Hydroxylation of Chlorzoxazone Following Traumatic Brain Injury in the Rat

  Samuel M. Poloyac, Alex Perez, Stephen Scheff and Robert A. Blouin

  Drug Metabolism and Disposition March 2001, 29 (3) 296-298;
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  Elevated Alpha-1-Acid Glycoprotein Reduces the Volume of Distribution and Systemic Clearance of Saquinavir

  John W. Holladay, Michael J. Dewey, Bozena B. Michniak, Hugh Wiltshire, Daniel L. Halberg, Paul Weigl, Zhenmin Liang, Kathryn Halifax, W. Edward Lindup and David J. Back

  Drug Metabolism and Disposition March 2001, 29 (3) 299-303;
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  P450 Enzyme Expression Patterns in the NCI Human Tumor Cell Line Panel

  Li J. Yu, Jocelyn Matias, Dominic A. Scudiero, Karen M. Hite, Anne Monks, Edward A. Sausville and David J. Waxman

  Drug Metabolism and Disposition March 2001, 29 (3) 304-312;
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  PSA-Specific and Non-PSA-Specific Conversion of a PSA-Targeted Peptide Conjugate of Doxorubicin to Its Active Metabolites

  Bradley K. Wong, Deborah DeFeo-Jones, Raymond E. Jones, Victor M. Garsky, Dong-Mei Feng, Allen Oliff, Masato Chiba, Joan D. Ellis and Jiunn H. Lin

  Drug Metabolism and Disposition March 2001, 29 (3) 313-318;
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  Variables in Human Liver Microsome Preparation: Impact on the Kinetics of L-α-Acetylmethadol (LAAM)N-Demethylation and DextromethorphanO-Demethylation

  Ann C. Nelson, Wei Huang and David E. Moody

  Drug Metabolism and Disposition March 2001, 29 (3) 319-325;
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  In Vivo Metabolism of 2,6,9-Trisubstituted Purine-Derived Cyclin-Dependent Kinase Inhibitor Bohemine in Mice: Glucosidation as the Principal Metabolic Route

  Zdeněk Chmela, Jaroslav Veselý, Karel Lemr, Miroslav Rypka, Jan Hanuš, Libor Havlı́ček, Vladimı́r Kryštof, Lucie Michnová, Květoslava Fuksová and Jiřı́ Lukeš

  Drug Metabolism and Disposition March 2001, 29 (3) 326-334;
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  Sulfation is Rate Limiting in the Futile Cycling Between Estrone and Estrone Sulfate in Enriched Periportal and Perivenous Rat Hepatocytes

  Eugene Tan and K. Sandy Pang

  Drug Metabolism and Disposition March 2001, 29 (3) 335-346;
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  Metabolic Characterization of the Major Human Small Intestinal Cytochrome P450s

  R. Scott Obach, Qing-Yu Zhang, Deborah Dunbar and Laurence S. Kaminsky

  Drug Metabolism and Disposition March 2001, 29 (3) 347-352;
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  Differential Induction of Rat Hepatic Cytochromes P450 3A1, 3A2, 2B1, 2B2, and 2E1 in Response to Pyridine Treatment

  Hyesook Kim, David A. Putt, Richard C. Zangar, C. Roland Wolf, F. Peter Guengerich, Robert J. Edwards, Paul F. Hollenberg and Raymond F. Novak

  Drug Metabolism and Disposition March 2001, 29 (3) 353-360;