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Research ArticleArticle

Elevated Alpha-1-Acid Glycoprotein Reduces the Volume of Distribution and Systemic Clearance of Saquinavir

John W. Holladay, Michael J. Dewey, Bozena B. Michniak, Hugh Wiltshire, Daniel L. Halberg, Paul Weigl, Zhenmin Liang, Kathryn Halifax, W. Edward Lindup and David J. Back
Drug Metabolism and Disposition March 2001, 29 (3) 299-303;
John W. Holladay
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Michael J. Dewey
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Bozena B. Michniak
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Hugh Wiltshire
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Daniel L. Halberg
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Paul Weigl
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Zhenmin Liang
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Kathryn Halifax
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W. Edward Lindup
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David J. Back
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Article Information

vol. 29 no. 3 299-303
PubMed 
11181499

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 23, 2000
  • Accepted October 11, 2000
  • Published online March 1, 2001.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. John W. Holladay1,
  2. Michael J. Dewey3,
  3. Bozena B. Michniak4,
  4. Hugh Wiltshire5,
  5. Daniel L. Halberg2,
  6. Paul Weigl6,
  7. Zhenmin Liang6,
  8. Kathryn Halifax7,
  9. W. Edward Lindup7 and
  10. David J. Back7
  1. Departments of 1Pharmaceutical Sciences (J.W.H.) and 2Pharmacy Practice (D.L.H.), College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Departments of 3Biological Sciences (M.J.D.) and 4Pharmaceutical Sciences (B.B.M.), University of South Carolina, Columbia, South Carolina; 5Roche Discovery, Welwyn, England (H.W.); 6Roche Laboratories, Nutley, New Jersey (P.W., Z.L.); and 7Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, England (K.H., W.E.L., D.J.B.)
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    Drug Metabolism and Disposition: 29 (3)
    Drug Metabolism and Disposition
    Vol. 29, Issue 3
    1 Mar 2001
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    Research ArticleArticle

    Elevated Alpha-1-Acid Glycoprotein Reduces the Volume of Distribution and Systemic Clearance of Saquinavir

    John W. Holladay, Michael J. Dewey, Bozena B. Michniak, Hugh Wiltshire, Daniel L. Halberg, Paul Weigl, Zhenmin Liang, Kathryn Halifax, W. Edward Lindup and David J. Back
    Drug Metabolism and Disposition March 1, 2001, 29 (3) 299-303;

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    Research ArticleArticle

    Elevated Alpha-1-Acid Glycoprotein Reduces the Volume of Distribution and Systemic Clearance of Saquinavir

    John W. Holladay, Michael J. Dewey, Bozena B. Michniak, Hugh Wiltshire, Daniel L. Halberg, Paul Weigl, Zhenmin Liang, Kathryn Halifax, W. Edward Lindup and David J. Back
    Drug Metabolism and Disposition March 1, 2001, 29 (3) 299-303;
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