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Research ArticleArticle

Prediction of Midazolam—cyp3a Inhibitors Interaction in the Human Liver from in Vivo/in Vitro Absorption, Distribution, and Metabolism Data

Katsuhiro Yamano, Koujirou Yamamoto, Masataka Katashima, Hajime Kotaki, Sayuri Takedomi, Hirotami Matsuo, Hisakazu Ohtani, Yasufumi Sawada and Tatsuji Iga
Drug Metabolism and Disposition April 2001, 29 (4) 443-452;

Article Information

vol. 29 no. 4 443-452
PubMed 
11259329
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 19, 2000
  • Accepted December 6, 2000
  • Published online April 1, 2001.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Katsuhiro Yamano1,2,
  2. Koujirou Yamamoto3,
  3. Masataka Katashima1,2,
  4. Hajime Kotaki4,
  5. Sayuri Takedomi5,
  6. Hirotami Matsuo5,
  7. Hisakazu Ohtani5,
  8. Yasufumi Sawada5 and
  9. Tatsuji Iga1
  1. 1Department of Pharmacy, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo, Hongo, Bunkyo-ku, Tokyo, Japan (Ka.Y., M.K., T.I.); 2Biopharmaceutical and Pharmacokinetic Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Kashima, Yodogawa-ku, Osaka, Japan (Ka.Y., M.K.); 3Department of Clinical Pharmacology School of Medicine, Gunma University, Showa-machi, Maebashi, Japan (Ko.Y.); 4Department of Pharmacy, The Research Hospital, The Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo, Japan (H.K.); and 5Graduate School of Pharmaceutical Sciences, Kyushu University, Maidashi, Higashi-ku, Fukuoka, Japan (S.T., H.M., H.O., Y.S.)
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    Research ArticleArticle

    Prediction of Midazolam—cyp3a Inhibitors Interaction in the Human Liver from in Vivo/in Vitro Absorption, Distribution, and Metabolism Data

    Katsuhiro Yamano, Koujirou Yamamoto, Masataka Katashima, Hajime Kotaki, Sayuri Takedomi, Hirotami Matsuo, Hisakazu Ohtani, Yasufumi Sawada and Tatsuji Iga
    Drug Metabolism and Disposition April 1, 2001, 29 (4) 443-452;
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