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Drug Metabolism & Disposition

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Table of Contents

May 01, 2001; Volume 29,Issue 5

MINIREVIEW

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    CYP3A Regulation: From Pharmacology to Nuclear Receptors
    Linda C. Quattrochi and Philip S. Guzelian
    Drug Metabolism and Disposition May 2001, 29 (5) 615-622;
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    Molecular Regulation of Genes Encoding Xenobiotic-Metabolizing Enzymes: Mechanisms Involving Endogenous Factors
    R. N. Hines, Z. Luo, T. Cresteil, X. Ding, R. A. Prough, J. L. Fitzpatrick, S. L. Ripp, K. C. Falkner, N.-L. Ge, A. Levine and C. J. Elferink
    Drug Metabolism and Disposition May 2001, 29 (5) 623-633;

Short Communication

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    Multidrug Resistance P-Glycoprotein 2 Is Essential for the Biliary Excretion of Indocyanine Green
    Liyue Huang and Mary Vore
    Drug Metabolism and Disposition May 2001, 29 (5) 634-637;

Articles

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    In Vitro Metabolism of the COX-2 Inhibitor DFU, Including a Novel Glutathione Adduct Rearomatization
    James A. Yergey, Laird A. Trimble, José Silva, Nathalie Chauret, Chun Li, Michel Therien, Erich Grimm and Deborah A. Nicoll-Griffith
    Drug Metabolism and Disposition May 2001, 29 (5) 638-644;
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    Accumulation of Nicotine and Its Metabolites in Rat Brain After Intermittent or Continuous Peripheral Administration of [2′-14C]Nicotine
    Omar A. Ghosheh, Linda P. Dwoskin, Dennis K. Miller and Peter A. Crooks
    Drug Metabolism and Disposition May 2001, 29 (5) 645-651;
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    13-Hydroxy- and 13-Oxooctadecadienoic acids: Novel Substrates for Human UDP-Glucuronosyltransferases
    Anthony R. Jude, Joanna M. Little, Arthur W. Bull, Izabela Podgorski and Anna Radominska-Pandya
    Drug Metabolism and Disposition May 2001, 29 (5) 652-655;
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    Metoprolol-Paroxetine Interaction in Human Liver Microsomes: Stereoselective Aspects and Prediction of the in Vivo Interaction
    Alex Hemeryck, Cindy A. De Vriendt and Frans M. Belpaire
    Drug Metabolism and Disposition May 2001, 29 (5) 656-663;
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    Dose-Dependent Pharmacokinetics and Metabolism of Valproic Acid in Newborn Lambs and Adult Sheep
    Harvey Wong, Dan W. Rurak, Sanjeev Kumar, Eddie Kwan, Frank S. Abbott and K. Wayne Riggs
    Drug Metabolism and Disposition May 2001, 29 (5) 664-675;
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    Spermidine/SpermineN 1-Acetyltransferase Catalyzes Amantadine Acetylation
    Alvaro P. M. Bras, Juhani Jänne, Carl W. Porter and Daniel S. Sitar
    Drug Metabolism and Disposition May 2001, 29 (5) 676-680;
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    Biodistribution of 4-[14C]Cholesterol-AmBisome following a Single Intravenous Administration to Rats
    Robert W. Townsend, Anup Zutshi and Ihor Bekersky
    Drug Metabolism and Disposition May 2001, 29 (5) 681-685;
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    Epirubicin Glucuronidation Is Catalyzed by Human UDP-Glucuronosyltransferase 2B7
    Federico Innocenti, Lalitha Iyer, Jacqueline Ramı́rez, Mitchell D. Green and Mark J. Ratain
    Drug Metabolism and Disposition May 2001, 29 (5) 686-692;
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    Characterization of Expressed Full-Length and Truncated FMO2 from Rhesus Monkey
    Sharon K. Krueger, Mei-Fei Yueh, Sarah R. Martin, Clifford B. Pereira and David E. Williams
    Drug Metabolism and Disposition May 2001, 29 (5) 693-700;
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    Metabolism of Sulfinpyrazone Sulfide and Sulfinpyrazone by Human Liver Microsomes and cDNA-Expressed Cytochrome P450s
    Minxia He, Allan E. Rettie, John Neal and William F. Trager
    Drug Metabolism and Disposition May 2001, 29 (5) 701-711;
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    An Assessment of Human Liver-Derived in Vitro Systems to Predict the in Vivo Metabolism and Clearance of Almokalant
    Tommy B. Andersson, Helena Sjöberg, Kurt-Jürgen Hoffmann, Alan R. Boobis, Patricia Watts, Robert J. Edwards, Brian G. Lake, Roger J. Price, Anthony B. Renwick, Maria J. Gómez-Lechón, José V. Castell, Magnus Ingelman-Sundberg, Mats Hidestrand, Peter S. Goldfarb, David F. V. Lewis, Laurent Corcos, André Guillouzo, Päivi Taavitsainen and Olavi Pelkonen
    Drug Metabolism and Disposition May 2001, 29 (5) 712-720;
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    Intestinal Bioavailability and Biotransformation of 3-Hydroxybenzo(a)pyrene in an Isolated Perfused Preparation from Channel Catfish, Ictalurus punctatus
    Margaret O. James, Zeen Tong, Laura Rowland-Faux, Changaram S. Venugopal and Kevin M. Kleinow
    Drug Metabolism and Disposition May 2001, 29 (5) 721-728;
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    Liquid Chromatography-Mass Spectrometry and Liquid Chromatography-NMR Characterization of in Vitro Metabolites of a Potent and Irreversible Peptidomimetic Inhibitor of Rhinovirus 3C Protease
    Kanyin E. Zhang, Brian Hee, Caroline A. Lee, Baihong Liang and Barbara C. M. Potts
    Drug Metabolism and Disposition May 2001, 29 (5) 729-734;
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    Involvement of Semicarbazide-Sensitive Amine Oxidase in Tresperimus Metabolism in Human and in Rat
    Philippe Claud, Paul Padovani, Jean-Pierre Guichard, Yves Artur and Romuald Lainé
    Drug Metabolism and Disposition May 2001, 29 (5) 735-741;
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    Effects of Receptor-Selective Retinoids on CYP26 Gene Expression and Metabolism of All-trans-Retinoic Acid in Intestinal Cells
    Alfonso Lampen, Silke Meyer and Heinz Nau
    Drug Metabolism and Disposition May 2001, 29 (5) 742-747;
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    Inhibition of CYP3A4 in a Rapid Microtiter Plate Assay Using Recombinant Enzyme and in Human Liver Microsomes Using Conventional Substrates
    Amin A. Nomeir, Charles Ruegg, Matthew Shoemaker, Leonard V. Favreau, Jairam R. Palamanda, Paul Silber and Chin-chung Lin
    Drug Metabolism and Disposition May 2001, 29 (5) 748-753;
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    Induction of P-Glycoprotein and Cytochrome P450 3A by HIV Protease Inhibitors
    Liyue Huang, Stephen A. Wring, Joseph L. Woolley, Kenneth R. Brouwer, Cosette Serabjit-Singh and Joseph W. Polli
    Drug Metabolism and Disposition May 2001, 29 (5) 754-760;
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    Verapamil Metabolism in Distinct Regions of the Heart and in Cultures of Cardiomyocytes of Adult Rats
    Markus Walles, Thomas Thum, Karsten Levsen and Jürgen Borlak
    Drug Metabolism and Disposition May 2001, 29 (5) 761-768;
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    Pharmacokinetics of Budesonide and Its Major Ester Metabolite after Inhalation and Intravenous Administration of Budesonide in the Rat
    Magnus Jendbro, Carl-Johan Johansson, Per Strandberg, Hanna Falk-Nilsson and Staffan Edsbäcker
    Drug Metabolism and Disposition May 2001, 29 (5) 769-776;

Letter to the Editor

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    Probenecid-Associated Alterations in Valproic Acid Pharmacokinetics in Rats: Can in Vivo Disposition of Valproate Glucuronide Be Predicted from in Vitro Formation Data?
    Swamy Yeleswaram
    Drug Metabolism and Disposition May 2001, 29 (5) 777;
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In this issue

Drug Metabolism and Disposition: 29 (5)
Drug Metabolism and Disposition
Vol. 29, Issue 5
1 May 2001
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  • Pharmacokinetics and Disposition of Biologics
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  • Tissue Drug Concentrations: Beyond the Free Drug Hypothesis
  • Metabolism and Disposition of Volanesorsen across Species
  • Transporter-Mediated Drug-Drug Interactions for E7766
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