Table of Contents

Articles

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  Cellular Distribution and Handling of Liver-Targeting Preparations in Human Livers Studied by a Liver Lobe Perfusion

  Barbro N. Melgert, Peter Olinga, Betty Weert, Maarten J. H. Slooff, Dirk K. F. Meijer, Klaas Poelstra and Geny M. M. Groothuis

  Drug Metabolism and Disposition June 2001, 29 (6) 361-367;
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  A Novel Cytochrome P450 Enzyme Responsible for the Metabolism of Ebastine in Monkey Small Intestine

  Takanori Hashizume, Masashi Mise, Satoshi Matsumoto, Yoshiaki Terauchi, Toshihiko Fujii, Susumu Imaoka, Yoshihiko Funae, Tetsuya Kamataki and Hisashi Miyazaki

  Drug Metabolism and Disposition June 2001, 29 (6) 798-805;
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  Identification of Rat Urinary and Biliary Metabolites of Esonarimod, a Novel Antirheumatic Drug, Using Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry with Postcolumn Addition of 2-(2-Methoxyethoxy)Ethanol, a Signal-Enhancing Modifier

  Jun-Ichi Yamaguchi, Mari Ohmichi, Masatoshi Hasegawa, Hideo Yoshida, Naoyoshi Ogawa and Shohei Higuchi

  Drug Metabolism and Disposition June 2001, 29 (6) 806-812;
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  Role of Human Liver Cytochrome P4503A in the Metabolism of Etoricoxib, a Novel Cyclooxygenase-2 Selective Inhibitor

  Kelem Kassahun, Ian S. McIntosh, Magang Shou, Deborah J. Walsh, Carey Rodeheffer, Donald E. Slaughter, Leslie A. Geer, Rita A. Halpin, Nancy Agrawal and A. David Rodrigues

  Drug Metabolism and Disposition June 2001, 29 (6) 813-820;
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  Effect of Ring Size in R-(+)-Pulegone-Mediated Hepatotoxicity: Studies on the Metabolism ofR-(+)-4-Methyl-2-(1-Methylethylidene)-Cyclopentanone anddl-Camphorone in Rats

  Hirekodathakallu V. Thulasiram, Vadiraja B. Bhat and Madhava K. Madyastha

  Drug Metabolism and Disposition June 2001, 29 (6) 821-829;
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  Metabolism of Butadiene Monoxide by Freshly Isolated Hepatocytes from Mice and Rats: Different Partitioning between Oxidative, Hydrolytic, and Conjugation Pathways

  Raymond A. Kemper, Renee J. Krause and Adnan A. Elfarra

  Drug Metabolism and Disposition June 2001, 29 (6) 830-836;
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  Clotrimazole is a Selective and Potent Inhibitor of Rat Cytochrome P450 3A Subfamily-Related Testosterone Metabolism

  Valerie K. Turan, Vladimir M. Mishin and Paul E. Thomas

  Drug Metabolism and Disposition June 2001, 29 (6) 837-842;
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  In Vivo and in Vitro Percutaneous Absorption of [¹⁴C]Di-n-Butylphthalate in Rat

  Jean-Paul Payan, Jean-Paul Marty, Jean-Paul Fabry, Dominique Beydon, Isabelle Boudry, Elisabeth Ferrari, Francine Canel, Marie-Christine Grandclaude and Claire Marie Vincent

  Drug Metabolism and Disposition June 2001, 29 (6) 843-854;
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  New Metabolic Pathways of α-Lipoic Acid

  Hubert Schupke, Roland Hempel, Gernot Peter, Robert Hermann, Klaus Wessel, Jürgen Engel and Thomas Kronbach

  Drug Metabolism and Disposition June 2001, 29 (6) 855-862;
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  Mechanism-Based Inactivation of CYP2D6 by 5-Fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine

  Jairam R. Palamanda, Christopher N. Casciano, Laura A. Norton, Robert P. Clement, Leonard V. Favreau, Chin-chung Lin and Amin A. Nomeir

  Drug Metabolism and Disposition June 2001, 29 (6) 863-867;
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  Toxicokinetics and Metabolism of 1,2-Diethylbenzene in Male Sprague Dawley Rats—Part 2: Evidence for in Vitro and in Vivo Stereoselectivity of 1,2-Diethylbenzene Metabolism

  Jean Paul Payan, Benoit Cossec, Dominique Beydon, Jean Paul Fabry and Elisabeth Ferrari

  Drug Metabolism and Disposition June 2001, 29 (6) 868-876;
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  In Vitro Stimulation of Warfarin Metabolism by Quinidine: Increases in the Formation of 4′- and 10-Hydroxywarfarin

  Jason S. Ngui, Qing Chen, Magang Shou, Regina W. Wang, Ralph A. Stearns, Thomas A. Baillie and Wei Tang

  Drug Metabolism and Disposition June 2001, 29 (6) 877-886;
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  Involvement of CYP2B6 in N-Demethylation of Ketamine in Human Liver Microsomes

  Yoshitsugu Yanagihara, Satoru Kariya, Michiteru Ohtani, Katsuyoshi Uchino, Takao Aoyama, Yoshikazu Yamamura and Tatsuji Iga

  Drug Metabolism and Disposition June 2001, 29 (6) 887-890;
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  Bioactivation of Tamoxifen to Metabolite E Quinone Methide: Reaction with Glutathione and DNA

  Peter W. Fan and Judy L. Bolton

  Drug Metabolism and Disposition June 2001, 29 (6) 891-896;
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  Evaluation of Methoxsalen, Tranylcypromine, and Tryptamine as Specific and Selective CYP2A6 Inhibitors in Vitro

  Wenjiang Zhang, Tansel Kilicarslan, Rachel F. Tyndale and Edward M. Sellers

  Drug Metabolism and Disposition June 2001, 29 (6) 897-902;
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  Direct Nuclear Magnetic Resonance Spectroscopic Analysis of ¹³C-Labeled Antipyrine Metabolites in Human Urine

  Kazuki Akira, Eiji Negishi, Misako Imachi and Takao Hashimoto

  Drug Metabolism and Disposition June 2001, 29 (6) 903-907;
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  Identification of Multiple Constitutive and Inducible Hepatic Cytochrome P450 Enzymes in Market Weight Swine

  Michael J. Myers, Dorothy E. Farrell, Karyn D. Howard and Joseph C. Kawalek

  Drug Metabolism and Disposition June 2001, 29 (6) 908-915;
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  CYP1B1 Expression in Human Lung

  Simon D. Spivack, Gregory J. Hurteau, Andrew A. Reilly, Kenneth M. Aldous, Xinxin Ding and Laurence S. Kaminsky

  Drug Metabolism and Disposition June 2001, 29 (6) 916-922;
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  Isolation and Identification of Clozapine Metabolites in Patient Urine

  Gisela Schaber, Gerlinde Wiatr, Helmut Wachsmuth, Markus Dachtler, Klaus Albert, Ines Gaertner and Ursula Breyer-Pfaff

  Drug Metabolism and Disposition June 2001, 29 (6) 923-931;