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Drug Metabolism & Disposition

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Table of Contents

July 01, 2001; Volume 29,Issue 7

Commentary

  • You have access
    Cassette Dosing Pharmacokinetics: Valuable Tool or Flawed Science?
    David D. Christ
    Drug Metabolism and Disposition July 2001, 29 (7) 935;

MINIREVIEW

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    Pharmacophore and Three-Dimensional Quantitative Structure Activity Relationship Methods for Modeling Cytochrome P450 Active Sites
    Sean Ekins, Marcel J. de Groot and Jeffrey P. Jones
    Drug Metabolism and Disposition July 2001, 29 (7) 936-944;

Short Communications

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    Pharmacokinetic Studies of 2-Amino-9-(3-acetoxymethyl-4-
    isopropoxycarbonyl-oxybut-1-yl)purine, an Oral Prodrug for the Antiviral Agent Penciclovir
    Won-Son Choi, Guang-Jin Im, Dae-Kee Kim, Tae-Kon Kim, Inho Jung, Taek-Soo Kim, Sung-Jae Lee, Namkyu Lee, Young-Woo Kim, Jae-Sun Kim and Kieyoung Chang
    Drug Metabolism and Disposition July 2001, 29 (7) 945-949;
  • You have access
    Selective Dehydrogenation/Oxygenation of 3-Methylindole by Cytochrome P450 Enzymes
    Diane L. Lanza and Garold S. Yost
    Drug Metabolism and Disposition July 2001, 29 (7) 950-953;
  • You have access
    Methadone Inhibits Rhodamine123 Transport in Caco-2 Cells
    Elke Störmer, Michael D. Perloff, Lisa L. von Moltke and David J. Greenblatt
    Drug Metabolism and Disposition July 2001, 29 (7) 954-956;
  • You have access
    Pharmacokinetic Theory of Cassette Dosing in Drug Discovery Screening
    Ronald E. White and Prasarn Manitpisitkul
    Drug Metabolism and Disposition July 2001, 29 (7) 957-966;
  • You have access
    Influence of Dose and Infusion Duration on Pharmacokinetics of Ifosfamide and Metabolites
    T. Kerbusch, R. A. A. Mathôt, H. J. Keizer, G. P. Kaijser, J. H. M. Schellens and J. H. Beijnen
    Drug Metabolism and Disposition July 2001, 29 (7) 967-975;
  • You have access
    Metabolism of Norethisterone and Norethisterone Derivatives in Rat Uterus, Vagina, and Aorta
    M. J. Blom, M. Groot Wassink, F. van Wijk, A. G. H. Ederveen, H. J. Kloosterboer, C. H. J. Verhoeven, J. G. D. Lambert and H. J. Th. Goos
    Drug Metabolism and Disposition July 2001, 29 (7) 976-982;
  • You have access
    Screening Of Organosulfur Compounds as Inhibitors of Human CYP2A6
    Ken-ichi Fujita and Tetsuya Kamataki
    Drug Metabolism and Disposition July 2001, 29 (7) 983-989;
  • You have access
    Bexarotene Metabolism in Rat, Dog, and Human, Synthesis of Oxidative Metabolites, and in Vitro Activity at Retinoid Receptors
    Stanley R. Howell, Michael A. Shirley, Timothy A. Grese, David A. Neel, Kirk E. Wells and Edgar H. Ulm
    Drug Metabolism and Disposition July 2001, 29 (7) 990-998;
  • You have access
    Polycyclic Aromatic Hydrocarbon/Metal Mixtures: Effect on PAH Induction of CYP1A1 in Human HepG2 Cells
    Dilip D. Vakharia, Ning Liu, Ronald Pause, Michael Fasco, Erin Bessette, Qing-Yu Zhang and Laurence S. Kaminsky
    Drug Metabolism and Disposition July 2001, 29 (7) 999-1006;
  • You have access
    Cytochrome P450 Down-Regulation by Serum from Humans with a Viral Infection and from Rabbits with an Inflammatory Reaction
    Anne-Marie Bleau, Caroline Fradette, Ayman O. S. El-Kadi, Marie-Claude Côté and Patrick du Souich
    Drug Metabolism and Disposition July 2001, 29 (7) 1007-1012;
  • You have access
    Dietary Uptake Kinetics of 2,2′,5,5′-Tetrachlorobiphenyl in Rainbow Trout
    J. W. Nichols, P. N. Fitzsimmons, F. W. Whiteman, D. W. Kuehl, B. C. Butterworth and C. T. Jenson
    Drug Metabolism and Disposition July 2001, 29 (7) 1013-1022;
  • You have access
    In Vivo Effect of Clarithromycin on Multiple Cytochrome P450s
    Melissa A. Bruce, Stephen D. Hall, Barbara D. Haehner-Daniels and J. Christopher Gorski
    Drug Metabolism and Disposition July 2001, 29 (7) 1023-1028;
  • You have access
    Dapsone Activation of CYP2C9-Mediated Metabolism: Evidence for Activation of Multiple Substrates and a Two-Site Model
    J. Matthew Hutzler, Michael J. Hauer and Timothy S. Tracy
    Drug Metabolism and Disposition July 2001, 29 (7) 1029-1034;
  • You have access
    In Vivo Pharmacokinetics and Metabolism of Anti-Human Immunodeficiency Virus Agent d4T-5′-[p-Bromophenyl Methoxyalaninyl Phosphate] (SAMPIDINE) in Mice
    Chun-Lin Chen, T. K. Venkatachalam, Zhao-Hai Zhu and Fatih M. Uckun
    Drug Metabolism and Disposition July 2001, 29 (7) 1035-1041;
  • You have access
    Studies Comparing in Vivo:in Vitro Metabolism of Three Pharmaceutical Compounds in Rat, Dog, Monkey, and Human Using Cryopreserved Hepatocytes, Microsomes, and Collagen Gel Immobilized Hepatocyte Cultures
    Nicola J. Hewitt, Karl-Uhlrich Bühring, Johannes Dasenbrock, Jutta Haunschild, Bernhard Ladstetter and Dietmar Utesch
    Drug Metabolism and Disposition July 2001, 29 (7) 1042-1050;
  • You have access
    Role of CYP2C9 Polymorphism in Losartan Oxidation
    Ümit Yasar, Gunnel Tybring, Mats Hidestrand, Mikael Oscarson, Magnus Ingelman-Sundberg, Marja-Liisa Dahl and Erik Eliasson
    Drug Metabolism and Disposition July 2001, 29 (7) 1051-1056;
  • You have access
    Cytochrome P450-Catalyzed Metabolism of Ezlopitant Alkene (CJ-12,458), a Pharmacologically Active Metabolite of Ezlopitant: Enzyme Kinetics and Mechanism Of an Alkene Hydration Reaction
    R. Scott Obach
    Drug Metabolism and Disposition July 2001, 29 (7) 1057-1067;
  • You have access
    Drug Interaction Between Simvastatin and Itraconazole in Male and Female Rats
    Michi Ishigami, Kiyoshi Kawabata, Wataru Takasaki, Toshihiko Ikeda, Toru Komai, Kiyomi Ito and Yuichi Sugiyama
    Drug Metabolism and Disposition July 2001, 29 (7) 1068-1072;
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In this issue

Drug Metabolism and Disposition: 29 (7)
Drug Metabolism and Disposition
Vol. 29, Issue 7
1 Jul 2001
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