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Drug Metabolism & Disposition

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Table of Contents

November 01, 1975; Volume 3,Issue 6
  • You have access
    IDENTIFICATION AND URINARY EXCRETION OF p-CHLOROPHENOXYACETAMIDE, A METABOLITE OF IPROCLOZIDE, IN HUMANS
    R. M. DE SAGHER, A. P. DE LEENHEER, A. A. CRUYL and A. E. CLAEYS
    Drug Metabolism and Disposition November 1975, 3 (6) 423-429;
  • You have access
    SEX-DEPENDENT DIFFERENCES IN THE BIOSYNTHESIS OF PYRIMIDINE NUCLEOTIDES IN RAT LIVER AFTER REPEATED ADMINISTRATION OFα -HEXACHLOROCYCLOHEXANE
    J. SEIFERT and J. VÁCHA
    Drug Metabolism and Disposition November 1975, 3 (6) 430-436;
  • You have access
    TISSUE METABOLITES OF TRIFLUOPERAZINE, FLUPHENAZINE, PROCHLORPERAZINE, AND PERPHENAZINE
    HANS JORG GAERTNER, GERHILD LIOMIN, DEBORAH VILLUMSEN, RUDOLF BERTELE and URSULA BREYER
    Drug Metabolism and Disposition November 1975, 3 (6) 437-444;
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    COMPARATIVE BIOTRANSFORMATION OF TRIFLUBAZAM IN RATS, DOGS, AND MONKEYS
    K. B. ALTON, J. E. PATRICK, C. SHAW and J. L. McGUIRE
    Drug Metabolism and Disposition November 1975, 3 (6) 445-452;
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    PHYSIOLOGICAL DISPOSITION AND METABOLISM OF 5-(2',4'-DIFLUOROPHENYL)SALICYCLIC ACID, A NEW SALICYLATE
    D. J. TOCCO, G. O. BREAULT, A. G. ZACCHEI, S. L. STEELMAN and C. V. PERRIER
    Drug Metabolism and Disposition November 1975, 3 (6) 453-466;
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    SPIRONOLACTONE METABOLISM IN MAN STUDIED BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY
    A. KARIM, J. HRIBAR, W. AKSAMIT, M. DOHERTY and L. J. CHINN
    Drug Metabolism and Disposition November 1975, 3 (6) 467-478;
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    N-HYDROXYAMOBARBITAL: THE SECOND MAJOR METABOLITE OF AMOBARBITAL IN MAN
    B. K. TANG, T. INABA and W. KALOW
    Drug Metabolism and Disposition November 1975, 3 (6) 479-486;
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    CORRELATION OF 14C-GRISEOFULVIN METABOLISM IN RAT LIVER MICROSOMES, ISOLATED PERFUSED RAT LIVERS, AND IN RATS WITH BILE DUCT CANNULAS
    R. L. CHANG, N. ZAMPAGLIONE and C. LIN
    Drug Metabolism and Disposition November 1975, 3 (6) 487-493;
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    OXIDATIVE BIOTRANSFORMATION OF 2-ACETYLAMINOFLUORENE IN FETAL AND PLACENTAL TISSUES OF HUMANS AND MONKEYS
    MONT R. JUCHAU, MOSES J. NAMKUNG, DAVID L. BERRY and PRINCE K. ZACHARIAH
    Drug Metabolism and Disposition November 1975, 3 (6) 494-501;
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    EFFECT OF 3-METHYLCHOLANTHRENE TREATMENT ON PHENACETIN O-DEALKYLATION IN SEVERAL INBRED MOUSE STRAINS
    P. J. POPPERS, W. LEVIN and A. H. CONNEY
    Drug Metabolism and Disposition November 1975, 3 (6) 502-506;
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    FURTHER STUDIES OF METYRAPONE EFFECTS UPON ANILIDE HYDROXYLATION
    KENNETH C. LEIBMAN and ELSA ORTIZ
    Drug Metabolism and Disposition November 1975, 3 (6) 507-512;
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    NATURE AND FATE OF INSECTICIDE RESIDUES INHALED BY RATS IN CIGARETTE SMOKE
    Y. H. ATALLAH, H. W. DOROUGH and J. H. THORSTENSON
    Drug Metabolism and Disposition November 1975, 3 (6) 513-519;
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    ABSORPTION AND DISPOSITION OF 2-[4-(2,2-DICHLOROCYCLOPROPYL)PHENOXY]-2-METHYL-PROPANOIC ACID, WIN 35,833, IN RATS, MONKEYS, AND MEN
    CLARKE DAVISON, DAVID BENZIGER, ALAN FRITZ and JEROME EDELSON
    Drug Metabolism and Disposition November 1975, 3 (6) 520-524;
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    THE GASTROINTESTINAL ABSORPTION OF METHADONE IN THE RAT
    CAROL T. WALSH, RUTH R. LEVINE and CHITRA SQUIRES
    Drug Metabolism and Disposition November 1975, 3 (6) 525-529;
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    BILIARY EXCRETION OF COLCHICINE IN NEWBORN RATS
    ANDREA L. HUNTER and CURTIS D. KLAASSEN
    Drug Metabolism and Disposition November 1975, 3 (6) 530-535;
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    DISPOSITION IN RATS OF A POLYOXYPROPYLENE-POLYOXYETHYLENE COPOLYMER USED IN PLASMA FRACTIONATION
    ZER-YUANG JO WANG and IVAN J. STERN
    Drug Metabolism and Disposition November 1975, 3 (6) 536-542;
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    UPTAKE AND DISPOSITION OF ALDRIN AND DIELDRIN BY ISOLATED PERFUSED RABBIT LUNG
    H. M. MEHENDALE and E. A. EL-BASSIOUNI
    Drug Metabolism and Disposition November 1975, 3 (6) 543-556;
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    KINETIC AND SPECTRAL STUDIES OF TYPE I AND TYPE II COMPOUNDS WITH RAT HEPATIC MICROSOMES IN THE PRESENCE OF THE MAJOR METABOLITE OF DIPHENYLHYDANTOIN
    S. A. STAVCHANSKY, H. B. KOSTENBAUDER and W. C. LUBAWY
    Drug Metabolism and Disposition November 1975, 3 (6) 557-564;
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    CHANGE IN THE KINETICS OF SULPHACETAMIDE TISSUE DISTRIBUTION IN WALKER TUMOR-BEARING RATS
    DENIS NADEAU and CLAUDE MARCHAND
    Drug Metabolism and Disposition November 1975, 3 (6) 565-576;
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    CYTOCHROME P-450 MEASUREMENT IN RAT LIVER HOMOGENATE AND MICROSOMES
    J.-G. JOLY, C. DOYON and Y. PESANT
    Drug Metabolism and Disposition November 1975, 3 (6) 577-586;
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    Isoniazid Acetylation and Hepatitis
    K. C. L.
    Drug Metabolism and Disposition November 1975, 3 (6) 587-588;
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    Pentobarbital Metabolite Inactivity
    K. C. L.
    Drug Metabolism and Disposition November 1975, 3 (6) 588-589;
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    Metabolism and Tolerance
    K. C. L.
    Drug Metabolism and Disposition November 1975, 3 (6) 588;
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    Review Serials
    K. C. L.
    Drug Metabolism and Disposition November 1975, 3 (6) 589-590;
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    Further Studies on Medazepam Metabolism in the Rat
    Rudolph W. Lucek, Claude B. Coutinho, Joyce A. Cheripko, John Ryan and Morton A. Schwartz
    Drug Metabolism and Disposition November 1975, 3 (6) 590;
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    Books Received
    Drug Metabolism and Disposition November 1975, 3 (6) 590;
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In this issue

Drug Metabolism and Disposition
Vol. 3, Issue 6
1 Nov 1975
  • Table of Contents
  • Index by author
  • Back Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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