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CYP1A-Mediated Metabolism of the Janus Kinase-3 Inhibitor 4-(4′-Hydroxyphenyl)-amino-6,7-
dimethoxyquinazoline: Structural Basis for Inactivation by Regioselective O-Demethylation

Fatih M. Uckun, Jason Thoen, Hao Chen, Elise Sudbeck, Chen Mao, Ravi Malaviya, Xing-Ping Liu and Chun-Lin Chen
Drug Metabolism and Disposition January 2002, 30 (1) 74-85; DOI: https://doi.org/10.1124/dmd.30.1.74
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Research ArticleArticle

CYP1A-Mediated Metabolism of the Janus Kinase-3 Inhibitor 4-(4′-Hydroxyphenyl)-amino-6,7-
dimethoxyquinazoline: Structural Basis for Inactivation by Regioselective O-Demethylation

Fatih M. Uckun, Jason Thoen, Hao Chen, Elise Sudbeck, Chen Mao, Ravi Malaviya, Xing-Ping Liu and Chun-Lin Chen
Drug Metabolism and Disposition January 1, 2002, 30 (1) 74-85; DOI: https://doi.org/10.1124/dmd.30.1.74
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