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Drug Metabolism & Disposition

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    • Current Issue
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Index by author

October 01, 2002; Volume 30,Issue 10
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

B

  1. Balani, Suresh K.

    1. You have access
      Effective Dosing Regimen of 1-Aminobenzotriazole for Inhibition of Antipyrine Clearance in Rats, Dogs, and Monkeys
      Suresh K. Balani, Tong Zhu, Tian J. Yang, Zhi Liu, Bing He and Frank W. Lee
      Drug Metabolism and Disposition October 2002, 30 (10) 1059-1062; DOI: https://doi.org/10.1124/dmd.30.10.1059
  2. Brockmöller, Jürgen

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108
  3. Buko, Alex M.

    1. You have access
      Implication of P450-Metabolite Complex Formation in the Nonlinear Pharmacokinetics and Metabolic Fate of (±)-(1′R*,3R*)-3-Phenyl-1-[(1′,2′,3′,4′-tetrahydro-5′,6′-methylene-dioxy-1′-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in Dogs
      James L. Ferrero, Samuel B. Thomas, Kennan C. Marsh, A. David Rodrigues, John T. Uchic and Alex M. Buko
      Drug Metabolism and Disposition October 2002, 30 (10) 1094-1101; DOI: https://doi.org/10.1124/dmd.30.10.1094
  4. Burk, Oliver

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108

C

  1. Cashman, John R.

    1. You have access
      Interindividual Differences of Human Flavin-Containing Monooxygenase 3: Genetic Polymorphisms and Functional Variation
      John R. Cashman and Jun Zhang
      Drug Metabolism and Disposition October 2002, 30 (10) 1043-1052; DOI: https://doi.org/10.1124/dmd.30.10.1043
  2. Cha, In-June

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  3. Cheon, S. S.

    1. You have access
      Metabolic Activation of 4-Hydroxyanisole by Isolated Rat Hepatocytes
      M. Y. Moridani, S. S. Cheon, S. Khan and P. J. O'Brien
      Drug Metabolism and Disposition October 2002, 30 (10) 1063-1069; DOI: https://doi.org/10.1124/dmd.30.10.1063
  4. Cole, Richard B.

    1. You have access
      In Vitro Metabolism ofR(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a Cannabinoid Receptor Agonist
      Qiang Zhang, Peng Ma, Marcus Iszard, Richard B. Cole, Weiqun Wang and Guangdi Wang
      Drug Metabolism and Disposition October 2002, 30 (10) 1077-1086; DOI: https://doi.org/10.1124/dmd.30.10.1077

D

  1. de Graaf, I. A. M.

    1. You have access
      Comparison of in Vitro Preparations for Semi-Quantitative Prediction of in Vivo Drug Metabolism
      I. A. M. de Graaf, C. E. van Meijeren, F. Pektaş and H. J. Koster
      Drug Metabolism and Disposition October 2002, 30 (10) 1129-1136; DOI: https://doi.org/10.1124/dmd.30.10.1129

E

  1. Eichelbaum, Michel

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108
  2. Elfarra, Adnan A.

    1. You have access
      Sulfoxides as Urinary Metabolites ofS-Allyl-l-Cysteine in Rats: Evidence for the Involvement of Flavin-Containing Monooxygenases
      Renee J. Krause, Steven C. Glocke and Adnan A. Elfarra
      Drug Metabolism and Disposition October 2002, 30 (10) 1137-1142; DOI: https://doi.org/10.1124/dmd.30.10.1137
  3. Eliasson, Erik

    1. You have access
      Reactive Intermediates and The Dynamics of Glutathione Transferases
      Rosanna Rinaldi, Erik Eliasson, Stellan Swedmark and Ralf Morgenstern
      Drug Metabolism and Disposition October 2002, 30 (10) 1053-1058; DOI: https://doi.org/10.1124/dmd.30.10.1053

F

  1. Ferrero, James L.

    1. You have access
      Implication of P450-Metabolite Complex Formation in the Nonlinear Pharmacokinetics and Metabolic Fate of (±)-(1′R*,3R*)-3-Phenyl-1-[(1′,2′,3′,4′-tetrahydro-5′,6′-methylene-dioxy-1′-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in Dogs
      James L. Ferrero, Samuel B. Thomas, Kennan C. Marsh, A. David Rodrigues, John T. Uchic and Alex M. Buko
      Drug Metabolism and Disposition October 2002, 30 (10) 1094-1101; DOI: https://doi.org/10.1124/dmd.30.10.1094
  2. Fisher, Michael B.

    1. You have access
      Flavin-Containing Monooxygenase Activity in Hepatocytes and Microsomes: In Vitro Characterization and In Vivo Scaling of Benzydamine Clearance
      Michael B. Fisher, Kwansik Yoon, Marcie L. Vaughn, Timothy J. Strelevitz and Robert S. Foti
      Drug Metabolism and Disposition October 2002, 30 (10) 1087-1093; DOI: https://doi.org/10.1124/dmd.30.10.1087
  3. Flockhart, David A.

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  4. Foti, Robert S.

    1. You have access
      Flavin-Containing Monooxygenase Activity in Hepatocytes and Microsomes: In Vitro Characterization and In Vivo Scaling of Benzydamine Clearance
      Michael B. Fisher, Kwansik Yoon, Marcie L. Vaughn, Timothy J. Strelevitz and Robert S. Foti
      Drug Metabolism and Disposition October 2002, 30 (10) 1087-1093; DOI: https://doi.org/10.1124/dmd.30.10.1087

G

  1. Ghosheh, Omar

    1. You have access
      Quaternary Ammonium-Linked Glucuronidation of 1-Substituted Imidazoles by Liver Microsomes: Interspecies Differences and Structure-Metabolism Relationships
      Sarvesh C. Vashishtha, Edward M. Hawes, Denis J. McCann, Omar Ghosheh and Lawrence Hogg
      Drug Metabolism and Disposition October 2002, 30 (10) 1070-1076; DOI: https://doi.org/10.1124/dmd.30.10.1070
  2. Glocke, Steven C.

    1. You have access
      Sulfoxides as Urinary Metabolites ofS-Allyl-l-Cysteine in Rats: Evidence for the Involvement of Flavin-Containing Monooxygenases
      Renee J. Krause, Steven C. Glocke and Adnan A. Elfarra
      Drug Metabolism and Disposition October 2002, 30 (10) 1137-1142; DOI: https://doi.org/10.1124/dmd.30.10.1137

H

  1. Hawes, Edward M.

    1. You have access
      Quaternary Ammonium-Linked Glucuronidation of 1-Substituted Imidazoles by Liver Microsomes: Interspecies Differences and Structure-Metabolism Relationships
      Sarvesh C. Vashishtha, Edward M. Hawes, Denis J. McCann, Omar Ghosheh and Lawrence Hogg
      Drug Metabolism and Disposition October 2002, 30 (10) 1070-1076; DOI: https://doi.org/10.1124/dmd.30.10.1070
  2. He, Bing

    1. You have access
      Effective Dosing Regimen of 1-Aminobenzotriazole for Inhibition of Antipyrine Clearance in Rats, Dogs, and Monkeys
      Suresh K. Balani, Tong Zhu, Tian J. Yang, Zhi Liu, Bing He and Frank W. Lee
      Drug Metabolism and Disposition October 2002, 30 (10) 1059-1062; DOI: https://doi.org/10.1124/dmd.30.10.1059
  3. Hecht, Stephen S.

    1. You have access
      Metabolism and Pharmacokinetics ofN′-Nitrosonornicotine in the Patas Monkey
      Pramod Upadhyaya, Cheryl L. Zimmerman and Stephen S. Hecht
      Drug Metabolism and Disposition October 2002, 30 (10) 1115-1122; DOI: https://doi.org/10.1124/dmd.30.10.1115
  4. Hogg, Lawrence

    1. You have access
      Quaternary Ammonium-Linked Glucuronidation of 1-Substituted Imidazoles by Liver Microsomes: Interspecies Differences and Structure-Metabolism Relationships
      Sarvesh C. Vashishtha, Edward M. Hawes, Denis J. McCann, Omar Ghosheh and Lawrence Hogg
      Drug Metabolism and Disposition October 2002, 30 (10) 1070-1076; DOI: https://doi.org/10.1124/dmd.30.10.1070
  5. Horie, Toshiharu

    1. You have access
      Diclofenac-Induced Inactivation of CYP3A4 and Its Stimulation by Quinidine
      Yasuhiro Masubuchi, Atsushi Ose and Toshiharu Horie
      Drug Metabolism and Disposition October 2002, 30 (10) 1143-1148; DOI: https://doi.org/10.1124/dmd.30.10.1143
  6. Hustert, Elisabeth

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108

I

  1. Iszard, Marcus

    1. You have access
      In Vitro Metabolism ofR(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a Cannabinoid Receptor Agonist
      Qiang Zhang, Peng Ma, Marcus Iszard, Richard B. Cole, Weiqun Wang and Guangdi Wang
      Drug Metabolism and Disposition October 2002, 30 (10) 1077-1086; DOI: https://doi.org/10.1124/dmd.30.10.1077

J

  1. Johnson, Kenneth L.

    1. You have access
      Cefazolin Administration and 2-Methyl-1,3,4-Thiadiazole-5-Thiol in Human Tissue: Possible Relationship to Hypoprothrombinemia
      Thomas C. Wood, Kenneth L. Johnson, Stephen Naylor and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2002, 30 (10) 1123-1128; DOI: https://doi.org/10.1124/dmd.30.10.1123

K

  1. Khan, S.

    1. You have access
      Metabolic Activation of 4-Hydroxyanisole by Isolated Rat Hepatocytes
      M. Y. Moridani, S. S. Cheon, S. Khan and P. J. O'Brien
      Drug Metabolism and Disposition October 2002, 30 (10) 1063-1069; DOI: https://doi.org/10.1124/dmd.30.10.1063
  2. Kim, Min-Jung

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  3. Kim, Sang-Woo

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  4. Koch, Ina

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108
  5. Koster, H. J.

    1. You have access
      Comparison of in Vitro Preparations for Semi-Quantitative Prediction of in Vivo Drug Metabolism
      I. A. M. de Graaf, C. E. van Meijeren, F. Pektaş and H. J. Koster
      Drug Metabolism and Disposition October 2002, 30 (10) 1129-1136; DOI: https://doi.org/10.1124/dmd.30.10.1129
  6. Krause, Renee J.

    1. You have access
      Sulfoxides as Urinary Metabolites ofS-Allyl-l-Cysteine in Rats: Evidence for the Involvement of Flavin-Containing Monooxygenases
      Renee J. Krause, Steven C. Glocke and Adnan A. Elfarra
      Drug Metabolism and Disposition October 2002, 30 (10) 1137-1142; DOI: https://doi.org/10.1124/dmd.30.10.1137

L

  1. Lee, Frank W.

    1. You have access
      Effective Dosing Regimen of 1-Aminobenzotriazole for Inhibition of Antipyrine Clearance in Rats, Dogs, and Monkeys
      Suresh K. Balani, Tong Zhu, Tian J. Yang, Zhi Liu, Bing He and Frank W. Lee
      Drug Metabolism and Disposition October 2002, 30 (10) 1059-1062; DOI: https://doi.org/10.1124/dmd.30.10.1059
  2. Lee, Sang-Seop

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  3. Liu, Zhi

    1. You have access
      Effective Dosing Regimen of 1-Aminobenzotriazole for Inhibition of Antipyrine Clearance in Rats, Dogs, and Monkeys
      Suresh K. Balani, Tong Zhu, Tian J. Yang, Zhi Liu, Bing He and Frank W. Lee
      Drug Metabolism and Disposition October 2002, 30 (10) 1059-1062; DOI: https://doi.org/10.1124/dmd.30.10.1059

M

  1. Ma, Peng

    1. You have access
      In Vitro Metabolism ofR(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a Cannabinoid Receptor Agonist
      Qiang Zhang, Peng Ma, Marcus Iszard, Richard B. Cole, Weiqun Wang and Guangdi Wang
      Drug Metabolism and Disposition October 2002, 30 (10) 1077-1086; DOI: https://doi.org/10.1124/dmd.30.10.1077
  2. Marsh, Kennan C.

    1. You have access
      Implication of P450-Metabolite Complex Formation in the Nonlinear Pharmacokinetics and Metabolic Fate of (±)-(1′R*,3R*)-3-Phenyl-1-[(1′,2′,3′,4′-tetrahydro-5′,6′-methylene-dioxy-1′-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in Dogs
      James L. Ferrero, Samuel B. Thomas, Kennan C. Marsh, A. David Rodrigues, John T. Uchic and Alex M. Buko
      Drug Metabolism and Disposition October 2002, 30 (10) 1094-1101; DOI: https://doi.org/10.1124/dmd.30.10.1094
  3. Masubuchi, Yasuhiro

    1. You have access
      Diclofenac-Induced Inactivation of CYP3A4 and Its Stimulation by Quinidine
      Yasuhiro Masubuchi, Atsushi Ose and Toshiharu Horie
      Drug Metabolism and Disposition October 2002, 30 (10) 1143-1148; DOI: https://doi.org/10.1124/dmd.30.10.1143
  4. McCann, Denis J.

    1. You have access
      Quaternary Ammonium-Linked Glucuronidation of 1-Substituted Imidazoles by Liver Microsomes: Interspecies Differences and Structure-Metabolism Relationships
      Sarvesh C. Vashishtha, Edward M. Hawes, Denis J. McCann, Omar Ghosheh and Lawrence Hogg
      Drug Metabolism and Disposition October 2002, 30 (10) 1070-1076; DOI: https://doi.org/10.1124/dmd.30.10.1070
  5. Morgenstern, Ralf

    1. You have access
      Reactive Intermediates and The Dynamics of Glutathione Transferases
      Rosanna Rinaldi, Erik Eliasson, Stellan Swedmark and Ralf Morgenstern
      Drug Metabolism and Disposition October 2002, 30 (10) 1053-1058; DOI: https://doi.org/10.1124/dmd.30.10.1053
  6. Moridani, M. Y.

    1. You have access
      Metabolic Activation of 4-Hydroxyanisole by Isolated Rat Hepatocytes
      M. Y. Moridani, S. S. Cheon, S. Khan and P. J. O'Brien
      Drug Metabolism and Disposition October 2002, 30 (10) 1063-1069; DOI: https://doi.org/10.1124/dmd.30.10.1063

N

  1. Naylor, Stephen

    1. You have access
      Cefazolin Administration and 2-Methyl-1,3,4-Thiadiazole-5-Thiol in Human Tissue: Possible Relationship to Hypoprothrombinemia
      Thomas C. Wood, Kenneth L. Johnson, Stephen Naylor and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2002, 30 (10) 1123-1128; DOI: https://doi.org/10.1124/dmd.30.10.1123
  2. Neuhaus, Peter

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108
  3. Nuessler, Andreas

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108

O

  1. O'Brien, P. J.

    1. You have access
      Metabolic Activation of 4-Hydroxyanisole by Isolated Rat Hepatocytes
      M. Y. Moridani, S. S. Cheon, S. Khan and P. J. O'Brien
      Drug Metabolism and Disposition October 2002, 30 (10) 1063-1069; DOI: https://doi.org/10.1124/dmd.30.10.1063
  2. Oh, Se-Wook

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  3. Ose, Atsushi

    1. You have access
      Diclofenac-Induced Inactivation of CYP3A4 and Its Stimulation by Quinidine
      Yasuhiro Masubuchi, Atsushi Ose and Toshiharu Horie
      Drug Metabolism and Disposition October 2002, 30 (10) 1143-1148; DOI: https://doi.org/10.1124/dmd.30.10.1143

P

  1. Park, Ji-Young

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  2. Pektaş, F.

    1. You have access
      Comparison of in Vitro Preparations for Semi-Quantitative Prediction of in Vivo Drug Metabolism
      I. A. M. de Graaf, C. E. van Meijeren, F. Pektaş and H. J. Koster
      Drug Metabolism and Disposition October 2002, 30 (10) 1129-1136; DOI: https://doi.org/10.1124/dmd.30.10.1129

R

  1. Rinaldi, Rosanna

    1. You have access
      Reactive Intermediates and The Dynamics of Glutathione Transferases
      Rosanna Rinaldi, Erik Eliasson, Stellan Swedmark and Ralf Morgenstern
      Drug Metabolism and Disposition October 2002, 30 (10) 1053-1058; DOI: https://doi.org/10.1124/dmd.30.10.1053
  2. Rodrigues, A. David

    1. You have access
      Implication of P450-Metabolite Complex Formation in the Nonlinear Pharmacokinetics and Metabolic Fate of (±)-(1′R*,3R*)-3-Phenyl-1-[(1′,2′,3′,4′-tetrahydro-5′,6′-methylene-dioxy-1′-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in Dogs
      James L. Ferrero, Samuel B. Thomas, Kennan C. Marsh, A. David Rodrigues, John T. Uchic and Alex M. Buko
      Drug Metabolism and Disposition October 2002, 30 (10) 1094-1101; DOI: https://doi.org/10.1124/dmd.30.10.1094

S

  1. Shin, Jae-Gook

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  2. Shon, Ji-Hong

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102
  3. Strelevitz, Timothy J.

    1. You have access
      Flavin-Containing Monooxygenase Activity in Hepatocytes and Microsomes: In Vitro Characterization and In Vivo Scaling of Benzydamine Clearance
      Michael B. Fisher, Kwansik Yoon, Marcie L. Vaughn, Timothy J. Strelevitz and Robert S. Foti
      Drug Metabolism and Disposition October 2002, 30 (10) 1087-1093; DOI: https://doi.org/10.1124/dmd.30.10.1087
  4. Swedmark, Stellan

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      Reactive Intermediates and The Dynamics of Glutathione Transferases
      Rosanna Rinaldi, Erik Eliasson, Stellan Swedmark and Ralf Morgenstern
      Drug Metabolism and Disposition October 2002, 30 (10) 1053-1058; DOI: https://doi.org/10.1124/dmd.30.10.1053

T

  1. Thomas, Samuel B.

    1. You have access
      Implication of P450-Metabolite Complex Formation in the Nonlinear Pharmacokinetics and Metabolic Fate of (±)-(1′R*,3R*)-3-Phenyl-1-[(1′,2′,3′,4′-tetrahydro-5′,6′-methylene-dioxy-1′-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in Dogs
      James L. Ferrero, Samuel B. Thomas, Kennan C. Marsh, A. David Rodrigues, John T. Uchic and Alex M. Buko
      Drug Metabolism and Disposition October 2002, 30 (10) 1094-1101; DOI: https://doi.org/10.1124/dmd.30.10.1094

U

  1. Uchic, John T.

    1. You have access
      Implication of P450-Metabolite Complex Formation in the Nonlinear Pharmacokinetics and Metabolic Fate of (±)-(1′R*,3R*)-3-Phenyl-1-[(1′,2′,3′,4′-tetrahydro-5′,6′-methylene-dioxy-1′-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200) in Dogs
      James L. Ferrero, Samuel B. Thomas, Kennan C. Marsh, A. David Rodrigues, John T. Uchic and Alex M. Buko
      Drug Metabolism and Disposition October 2002, 30 (10) 1094-1101; DOI: https://doi.org/10.1124/dmd.30.10.1094
  2. Upadhyaya, Pramod

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      Metabolism and Pharmacokinetics ofN′-Nitrosonornicotine in the Patas Monkey
      Pramod Upadhyaya, Cheryl L. Zimmerman and Stephen S. Hecht
      Drug Metabolism and Disposition October 2002, 30 (10) 1115-1122; DOI: https://doi.org/10.1124/dmd.30.10.1115

V

  1. van Meijeren, C. E.

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      Comparison of in Vitro Preparations for Semi-Quantitative Prediction of in Vivo Drug Metabolism
      I. A. M. de Graaf, C. E. van Meijeren, F. Pektaş and H. J. Koster
      Drug Metabolism and Disposition October 2002, 30 (10) 1129-1136; DOI: https://doi.org/10.1124/dmd.30.10.1129
  2. Vashishtha, Sarvesh C.

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      Quaternary Ammonium-Linked Glucuronidation of 1-Substituted Imidazoles by Liver Microsomes: Interspecies Differences and Structure-Metabolism Relationships
      Sarvesh C. Vashishtha, Edward M. Hawes, Denis J. McCann, Omar Ghosheh and Lawrence Hogg
      Drug Metabolism and Disposition October 2002, 30 (10) 1070-1076; DOI: https://doi.org/10.1124/dmd.30.10.1070
  3. Vaughn, Marcie L.

    1. You have access
      Flavin-Containing Monooxygenase Activity in Hepatocytes and Microsomes: In Vitro Characterization and In Vivo Scaling of Benzydamine Clearance
      Michael B. Fisher, Kwansik Yoon, Marcie L. Vaughn, Timothy J. Strelevitz and Robert S. Foti
      Drug Metabolism and Disposition October 2002, 30 (10) 1087-1093; DOI: https://doi.org/10.1124/dmd.30.10.1087

W

  1. Wang, Guangdi

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      In Vitro Metabolism ofR(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a Cannabinoid Receptor Agonist
      Qiang Zhang, Peng Ma, Marcus Iszard, Richard B. Cole, Weiqun Wang and Guangdi Wang
      Drug Metabolism and Disposition October 2002, 30 (10) 1077-1086; DOI: https://doi.org/10.1124/dmd.30.10.1077
  2. Wang, Weiqun

    1. You have access
      In Vitro Metabolism ofR(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a Cannabinoid Receptor Agonist
      Qiang Zhang, Peng Ma, Marcus Iszard, Richard B. Cole, Weiqun Wang and Guangdi Wang
      Drug Metabolism and Disposition October 2002, 30 (10) 1077-1086; DOI: https://doi.org/10.1124/dmd.30.10.1077
  3. Weil, Regina

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      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108
  4. Weinshilboum, Richard M.

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      Cefazolin Administration and 2-Methyl-1,3,4-Thiadiazole-5-Thiol in Human Tissue: Possible Relationship to Hypoprothrombinemia
      Thomas C. Wood, Kenneth L. Johnson, Stephen Naylor and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2002, 30 (10) 1123-1128; DOI: https://doi.org/10.1124/dmd.30.10.1123
  5. Wojnowski, Leszek

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108
  6. Wolbold, Renzo

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108
  7. Wood, Thomas C.

    1. You have access
      Cefazolin Administration and 2-Methyl-1,3,4-Thiadiazole-5-Thiol in Human Tissue: Possible Relationship to Hypoprothrombinemia
      Thomas C. Wood, Kenneth L. Johnson, Stephen Naylor and Richard M. Weinshilboum
      Drug Metabolism and Disposition October 2002, 30 (10) 1123-1128; DOI: https://doi.org/10.1124/dmd.30.10.1123

Y

  1. Yang, Tian J.

    1. You have access
      Effective Dosing Regimen of 1-Aminobenzotriazole for Inhibition of Antipyrine Clearance in Rats, Dogs, and Monkeys
      Suresh K. Balani, Tong Zhu, Tian J. Yang, Zhi Liu, Bing He and Frank W. Lee
      Drug Metabolism and Disposition October 2002, 30 (10) 1059-1062; DOI: https://doi.org/10.1124/dmd.30.10.1059
  2. Yoon, Kwansik

    1. You have access
      Flavin-Containing Monooxygenase Activity in Hepatocytes and Microsomes: In Vitro Characterization and In Vivo Scaling of Benzydamine Clearance
      Michael B. Fisher, Kwansik Yoon, Marcie L. Vaughn, Timothy J. Strelevitz and Robert S. Foti
      Drug Metabolism and Disposition October 2002, 30 (10) 1087-1093; DOI: https://doi.org/10.1124/dmd.30.10.1087
  3. Yoon, Young-Ran

    1. You have access
      Inhibitory Effects of Tricyclic Antidepressants (TCAs) on Human Cytochrome P450 Enzymes in Vitro: Mechanism of Drug Interaction between TCAs and Phenytoin
      Jae-Gook Shin, Ji-Young Park, Min-Jung Kim, Ji-Hong Shon, Young-Ran Yoon, In-June Cha, Sang-Seop Lee, Se-Wook Oh, Sang-Woo Kim and David A. Flockhart
      Drug Metabolism and Disposition October 2002, 30 (10) 1102-1107; DOI: https://doi.org/10.1124/dmd.30.10.1102

Z

  1. Zanger, Ulrich

    1. You have access
      Interindividual Variability and Tissue-Specificity in the Expression of Cytochrome P450 3A mRNA
      Ina Koch, Regina Weil, Renzo Wolbold, Jürgen Brockmöller, Elisabeth Hustert, Oliver Burk, Andreas Nuessler, Peter Neuhaus, Michel Eichelbaum, Ulrich Zanger and Leszek Wojnowski
      Drug Metabolism and Disposition October 2002, 30 (10) 1108-1114; DOI: https://doi.org/10.1124/dmd.30.10.1108
  2. Zhang, Jun

    1. You have access
      Interindividual Differences of Human Flavin-Containing Monooxygenase 3: Genetic Polymorphisms and Functional Variation
      John R. Cashman and Jun Zhang
      Drug Metabolism and Disposition October 2002, 30 (10) 1043-1052; DOI: https://doi.org/10.1124/dmd.30.10.1043
  3. Zhang, Qiang

    1. You have access
      In Vitro Metabolism ofR(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]1,4-benzoxazinyl]-(1-naphthalenyl) methanone mesylate, a Cannabinoid Receptor Agonist
      Qiang Zhang, Peng Ma, Marcus Iszard, Richard B. Cole, Weiqun Wang and Guangdi Wang
      Drug Metabolism and Disposition October 2002, 30 (10) 1077-1086; DOI: https://doi.org/10.1124/dmd.30.10.1077
  4. Zhu, Tong

    1. You have access
      Effective Dosing Regimen of 1-Aminobenzotriazole for Inhibition of Antipyrine Clearance in Rats, Dogs, and Monkeys
      Suresh K. Balani, Tong Zhu, Tian J. Yang, Zhi Liu, Bing He and Frank W. Lee
      Drug Metabolism and Disposition October 2002, 30 (10) 1059-1062; DOI: https://doi.org/10.1124/dmd.30.10.1059
  5. Zimmerman, Cheryl L.

    1. You have access
      Metabolism and Pharmacokinetics ofN′-Nitrosonornicotine in the Patas Monkey
      Pramod Upadhyaya, Cheryl L. Zimmerman and Stephen S. Hecht
      Drug Metabolism and Disposition October 2002, 30 (10) 1115-1122; DOI: https://doi.org/10.1124/dmd.30.10.1115
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Drug Metabolism and Disposition: 30 (10)
Drug Metabolism and Disposition
Vol. 30, Issue 10
1 Oct 2002
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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