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Review ArticleMINIREVIEW

Interindividual Differences of Human Flavin-Containing Monooxygenase 3: Genetic Polymorphisms and Functional Variation

John R. Cashman and Jun Zhang
Drug Metabolism and Disposition October 2002, 30 (10) 1043-1052; DOI: https://doi.org/10.1124/dmd.30.10.1043
John R. Cashman
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Article Information

vol. 30 no. 10 1043-1052
DOI 
https://doi.org/10.1124/dmd.30.10.1043
PubMed 
12228178

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 15, 2002
  • Accepted July 15, 2002
  • Published online October 1, 2002.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. John R. Cashman and
  2. Jun Zhang
  1. Human BioMolecular Research Institute, San Diego, California
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    In this issue

    Drug Metabolism and Disposition: 30 (10)
    Drug Metabolism and Disposition
    Vol. 30, Issue 10
    1 Oct 2002
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    Review ArticleMINIREVIEW

    Interindividual Differences of Human Flavin-Containing Monooxygenase 3: Genetic Polymorphisms and Functional Variation

    John R. Cashman and Jun Zhang
    Drug Metabolism and Disposition October 1, 2002, 30 (10) 1043-1052; DOI: https://doi.org/10.1124/dmd.30.10.1043

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    Review ArticleMINIREVIEW

    Interindividual Differences of Human Flavin-Containing Monooxygenase 3: Genetic Polymorphisms and Functional Variation

    John R. Cashman and Jun Zhang
    Drug Metabolism and Disposition October 1, 2002, 30 (10) 1043-1052; DOI: https://doi.org/10.1124/dmd.30.10.1043
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    • Article
      • Abstract
      • Hepatic Human FMO
      • Human FMO3 Substrate Specificity
      • Extra Hepatic Human FMO
      • Interindividual Variability of Human FMO3 Functional Activity: In Vitro Considerations
      • Interindividual Variability of Human FMO3 Functional Activity: In Vivo Considerations
      • FMO Gene Organization
      • Biochemical Properties of FMO: Modulation and Regulation
      • Common Polymorphisms of Human FMO3 Genes and Haplotype Analysis in Ethnic Groups
      • Human FMO3 Polymorphism Analysis and Other Considerations
      • An Example of a Human FMO3 Polymorphism Associated with Ethnicity
      • Rare Human FMO3 Mutations
      • Human FMO3 Variants Associated with Transient Trimethylaminuria
      • Conclusions
      • Acknowledgments
      • Note Added in Proof.
      • Footnotes
      • References
      • Footnotes
    • Figures & Data
    • Info & Metrics
    • eLetters
    • PDF

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