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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

December 01, 2002; Volume 30,Issue 12
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Austin, Rupert P.

    1. You have access
      The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties
      Rupert P. Austin, Patrick Barton, Scott L. Cockroft, Mark C. Wenlock and Robert J. Riley
      Drug Metabolism and Disposition December 2002, 30 (12) 1497-1503; DOI: https://doi.org/10.1124/dmd.30.12.1497
  2. Awasthi, Sanjay

    1. You have access
      RLIP76, a Novel Transporter Catalyzing ATP-Dependent Efflux of Xenobiotics
      Sanjay Awasthi, Rajendra Sharma, Sharad S. Singhal, Piotr Zimniak and Yogesh C. Awasthi
      Drug Metabolism and Disposition December 2002, 30 (12) 1300-1310; DOI: https://doi.org/10.1124/dmd.30.12.1300
  3. Awasthi, Yogesh C.

    1. You have access
      RLIP76, a Novel Transporter Catalyzing ATP-Dependent Efflux of Xenobiotics
      Sanjay Awasthi, Rajendra Sharma, Sharad S. Singhal, Piotr Zimniak and Yogesh C. Awasthi
      Drug Metabolism and Disposition December 2002, 30 (12) 1300-1310; DOI: https://doi.org/10.1124/dmd.30.12.1300

B

  1. Backman, Janne T.

    1. You have access
      Gemfibrozil Inhibits CYP2C8-Mediated Cerivastatin Metabolism in Human Liver Microsomes
      Jun-Sheng Wang, Mikko Neuvonen, Xia Wen, Janne T. Backman and Pertti J. Neuvonen
      Drug Metabolism and Disposition December 2002, 30 (12) 1352-1356; DOI: https://doi.org/10.1124/dmd.30.12.1352
  2. Bailey, Nigel J.C.

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357
  3. Barton, Patrick

    1. You have access
      The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties
      Rupert P. Austin, Patrick Barton, Scott L. Cockroft, Mark C. Wenlock and Robert J. Riley
      Drug Metabolism and Disposition December 2002, 30 (12) 1497-1503; DOI: https://doi.org/10.1124/dmd.30.12.1497
  4. Berry, Loren M.

    1. You have access
      Involvement of CYP3A in the Metabolism of Eplerenone in Humans and Dogs: Differential Metabolism by CYP3A4 and CYP3A5
      Chyung S. Cook, Loren M. Berry, David H. Kim, Earl G. Burton, Jeremy D. Hribar and Liming Zhang
      Drug Metabolism and Disposition December 2002, 30 (12) 1344-1351; DOI: https://doi.org/10.1124/dmd.30.12.1344
  5. Beydon, Dominique

    1. You have access
      Toxicokinetics and Metabolism ofN-[14C]Methylpyrrolidone in Male Sprague-Dawley Rats. A Saturable NMP Elimination Process
      Jean-Paul Payan, Dominique Beydon, Jean-Paul Fabry, Isabelle Boudry, Benoit Cossec and Elisabeth Ferrari
      Drug Metabolism and Disposition December 2002, 30 (12) 1418-1424; DOI: https://doi.org/10.1124/dmd.30.12.1418
  6. Bhathena, Anahita

    1. You have access
      Suppression of Cytochrome P450 2C11 by Aromatic Hydrocarbons: Mechanistic Insights from Studies of the 5′-Flanking Region of theCYP2C11 Gene
      Anahita Bhathena, Chunja Lee and David S. Riddick
      Drug Metabolism and Disposition December 2002, 30 (12) 1385-1392; DOI: https://doi.org/10.1124/dmd.30.12.1385
  7. Blaschke, Terrence F.

    1. You have access
      Model-based Analysis of the Pharmacokinetic Interactions Between Ritonavir, Nelfinavir, and Saquinavir after Simultaneous and Staggered Oral Administration
      Jian-Feng Lu, Terrence F. Blaschke, Charles Flexner, Susan L. Rosenkranz, Lewis B. Sheiner and AIDS Clinical Trials Group Protocol 378 Investigators
      Drug Metabolism and Disposition December 2002, 30 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.30.12.1455
  8. Bonner, Heather S.

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425
  9. Borgeaud, Nathan

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357
  10. Boudry, Isabelle

    1. You have access
      Toxicokinetics and Metabolism ofN-[14C]Methylpyrrolidone in Male Sprague-Dawley Rats. A Saturable NMP Elimination Process
      Jean-Paul Payan, Dominique Beydon, Jean-Paul Fabry, Isabelle Boudry, Benoit Cossec and Elisabeth Ferrari
      Drug Metabolism and Disposition December 2002, 30 (12) 1418-1424; DOI: https://doi.org/10.1124/dmd.30.12.1418
  11. Buhler, Donald R.

    1. You have access
      Functional Properties of a Rainbow Trout CYP3A27 Expressed by Recombinant Baculovirus in Insect Cells
      Su-Jun Lee and Donald R. Buhler
      Drug Metabolism and Disposition December 2002, 30 (12) 1406-1412; DOI: https://doi.org/10.1124/dmd.30.12.1406
  12. Burton, Earl G.

    1. You have access
      Involvement of CYP3A in the Metabolism of Eplerenone in Humans and Dogs: Differential Metabolism by CYP3A4 and CYP3A5
      Chyung S. Cook, Loren M. Berry, David H. Kim, Earl G. Burton, Jeremy D. Hribar and Liming Zhang
      Drug Metabolism and Disposition December 2002, 30 (12) 1344-1351; DOI: https://doi.org/10.1124/dmd.30.12.1344

C

  1. Cai, Hongbo

    1. You have access
      Regulation of CYP2B6 and CYP3A Expression by Hydroxymethylglutaryl Coenzyme A Inhibitors in Primary Cultured Human Hepatocytes
      Thomas A. Kocarek, Michael S. Dahn, Hongbo Cai, Stephen C. Strom and Nancy A. Mercer-Haines
      Drug Metabolism and Disposition December 2002, 30 (12) 1400-1405; DOI: https://doi.org/10.1124/dmd.30.12.1400
  2. Carter, K. M.

    1. You have access
      Irreversible Inhibition of CYP2D6 by (−)-Chloroephedrine, a Possible Impurity in Methamphetamine
      B. Rege, K. M. Carter, M. A. Sarkar, G. E. Kellogg and W. H. Soine
      Drug Metabolism and Disposition December 2002, 30 (12) 1337-1343; DOI: https://doi.org/10.1124/dmd.30.12.1337
  3. Chen, Chun-Lin

    1. You have access
      Metabolism of Stavudine-5′-[p-Bromophenyl Methoxyalaninyl Phosphate], Stampidine, in Mice, Dogs, and Cats
      Chun-Lin Chen, Gengli Yu, T. K. Venkatachalam and Fatih M. Uckun
      Drug Metabolism and Disposition December 2002, 30 (12) 1523-1531; DOI: https://doi.org/10.1124/dmd.30.12.1523
  4. Cheng, K.-C.

    1. You have access
      Development of a Novel in Vitro Model to Predict Hepatic Clearance Using Fresh, Cryopreserved, and Sandwich-Cultured Hepatocytes
      Yau Yi Lau, Elpida Sapidou, Xiaoming Cui, Ronald E. White and K.-C. Cheng
      Drug Metabolism and Disposition December 2002, 30 (12) 1446-1454; DOI: https://doi.org/10.1124/dmd.30.12.1446
  5. Clarke, Stephen E.

    1. You have access
      Quinidine and Haloperidol as Modifiers of CYP3A4 Activity: Multisite Kinetic Model Approach
      Aleksandra Galetin, Stephen E. Clarke and J. Brian Houston
      Drug Metabolism and Disposition December 2002, 30 (12) 1512-1522; DOI: https://doi.org/10.1124/dmd.30.12.1512
  6. Cockroft, Scott L.

    1. You have access
      The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties
      Rupert P. Austin, Patrick Barton, Scott L. Cockroft, Mark C. Wenlock and Robert J. Riley
      Drug Metabolism and Disposition December 2002, 30 (12) 1497-1503; DOI: https://doi.org/10.1124/dmd.30.12.1497
  7. Connelly, John C.

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357
  8. Connor, Susan C.

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357
  9. Cook, Chyung S.

    1. You have access
      Involvement of CYP3A in the Metabolism of Eplerenone in Humans and Dogs: Differential Metabolism by CYP3A4 and CYP3A5
      Chyung S. Cook, Loren M. Berry, David H. Kim, Earl G. Burton, Jeremy D. Hribar and Liming Zhang
      Drug Metabolism and Disposition December 2002, 30 (12) 1344-1351; DOI: https://doi.org/10.1124/dmd.30.12.1344
  10. Cook, James M.

    1. You have access
      Enzyme Kinetics for the Formation of 3-Hydroxyquinine and Three New Metabolites of Quinine in Vitro; 3-Hydroxylation by CYP3A4 is Indeed the Major Metabolic Pathway
      Rajaa A. Mirghani, Ümit Yasar, Tao Zheng, James M. Cook, Lars L. Gustafsson, Gunnel Tybring and Örjan Ericsson
      Drug Metabolism and Disposition December 2002, 30 (12) 1368-1371; DOI: https://doi.org/10.1124/dmd.30.12.1368
  11. Cossec, Benoit

    1. You have access
      Toxicokinetics and Metabolism ofN-[14C]Methylpyrrolidone in Male Sprague-Dawley Rats. A Saturable NMP Elimination Process
      Jean-Paul Payan, Dominique Beydon, Jean-Paul Fabry, Isabelle Boudry, Benoit Cossec and Elisabeth Ferrari
      Drug Metabolism and Disposition December 2002, 30 (12) 1418-1424; DOI: https://doi.org/10.1124/dmd.30.12.1418
  12. Cui, Xiaoming

    1. You have access
      Development of a Novel in Vitro Model to Predict Hepatic Clearance Using Fresh, Cryopreserved, and Sandwich-Cultured Hepatocytes
      Yau Yi Lau, Elpida Sapidou, Xiaoming Cui, Ronald E. White and K.-C. Cheng
      Drug Metabolism and Disposition December 2002, 30 (12) 1446-1454; DOI: https://doi.org/10.1124/dmd.30.12.1446

D

  1. Dabrowiak, James C.

    1. You have access
      Kinetic Study of the Reaction of Cisplatin with Thiols
      James C. Dabrowiak, Jerry Goodisman and Abdul-Kader Souid
      Drug Metabolism and Disposition December 2002, 30 (12) 1378-1384; DOI: https://doi.org/10.1124/dmd.30.12.1378
  2. Dahn, Michael S.

    1. You have access
      Regulation of CYP2B6 and CYP3A Expression by Hydroxymethylglutaryl Coenzyme A Inhibitors in Primary Cultured Human Hepatocytes
      Thomas A. Kocarek, Michael S. Dahn, Hongbo Cai, Stephen C. Strom and Nancy A. Mercer-Haines
      Drug Metabolism and Disposition December 2002, 30 (12) 1400-1405; DOI: https://doi.org/10.1124/dmd.30.12.1400
  3. Davidson, Jeffrey N.

    1. You have access
      Dihydroorotase Catalyzes the Ring Opening of the Hydrolysis Intermediates of the Cardioprotective Drug Dexrazoxane (ICRF-187)
      Patricia E. Schroeder, Jeffrey N. Davidson and Brian B. Hasinoff
      Drug Metabolism and Disposition December 2002, 30 (12) 1431-1435; DOI: https://doi.org/10.1124/dmd.30.12.1431
  4. DeRemer, Susan J.

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425
  5. Dou, Chunzhi

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425

E

  1. Elaut, G.

    1. You have access
      Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver Microsomes
      G. Elaut, G. Török, M. Vinken, G. Laus, P. Papeleu, D. Tourwe and V. Rogiers
      Drug Metabolism and Disposition December 2002, 30 (12) 1320-1328; DOI: https://doi.org/10.1124/dmd.30.12.1320
  2. Ensminger, William D.

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425
  3. Ericsson, Örjan

    1. You have access
      Enzyme Kinetics for the Formation of 3-Hydroxyquinine and Three New Metabolites of Quinine in Vitro; 3-Hydroxylation by CYP3A4 is Indeed the Major Metabolic Pathway
      Rajaa A. Mirghani, Ümit Yasar, Tao Zheng, James M. Cook, Lars L. Gustafsson, Gunnel Tybring and Örjan Ericsson
      Drug Metabolism and Disposition December 2002, 30 (12) 1368-1371; DOI: https://doi.org/10.1124/dmd.30.12.1368

F

  1. Fabry, Jean-Paul

    1. You have access
      Toxicokinetics and Metabolism ofN-[14C]Methylpyrrolidone in Male Sprague-Dawley Rats. A Saturable NMP Elimination Process
      Jean-Paul Payan, Dominique Beydon, Jean-Paul Fabry, Isabelle Boudry, Benoit Cossec and Elisabeth Ferrari
      Drug Metabolism and Disposition December 2002, 30 (12) 1418-1424; DOI: https://doi.org/10.1124/dmd.30.12.1418
  2. Ferrari, Elisabeth

    1. You have access
      Toxicokinetics and Metabolism ofN-[14C]Methylpyrrolidone in Male Sprague-Dawley Rats. A Saturable NMP Elimination Process
      Jean-Paul Payan, Dominique Beydon, Jean-Paul Fabry, Isabelle Boudry, Benoit Cossec and Elisabeth Ferrari
      Drug Metabolism and Disposition December 2002, 30 (12) 1418-1424; DOI: https://doi.org/10.1124/dmd.30.12.1418
  3. Flexner, Charles

    1. You have access
      Model-based Analysis of the Pharmacokinetic Interactions Between Ritonavir, Nelfinavir, and Saquinavir after Simultaneous and Staggered Oral Administration
      Jian-Feng Lu, Terrence F. Blaschke, Charles Flexner, Susan L. Rosenkranz, Lewis B. Sheiner and AIDS Clinical Trials Group Protocol 378 Investigators
      Drug Metabolism and Disposition December 2002, 30 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.30.12.1455
  4. Fuse, Eiichi

    1. You have access
      Effects of Olopatadine, a New Antiallergic Agent, on Human Liver Microsomal Cytochrome P450 Activities
      Jiro Kajita, Keiko Inano, Eiichi Fuse, Takashi Kuwabara and Hiroyuki Kobayashi
      Drug Metabolism and Disposition December 2002, 30 (12) 1504-1511; DOI: https://doi.org/10.1124/dmd.30.12.1504

G

  1. Galetin, Aleksandra

    1. You have access
      Quinidine and Haloperidol as Modifiers of CYP3A4 Activity: Multisite Kinetic Model Approach
      Aleksandra Galetin, Stephen E. Clarke and J. Brian Houston
      Drug Metabolism and Disposition December 2002, 30 (12) 1512-1522; DOI: https://doi.org/10.1124/dmd.30.12.1512
  2. Gavaghan, Claire L.

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357
  3. Ghosheh, Omar

    1. You have access
      Microsomal N-Glucuronidation of Nicotine and Cotinine: Human Hepatic Interindividual, Human Intertissue, and Interspecies Hepatic Variation
      Omar Ghosheh and Edward M. Hawes
      Drug Metabolism and Disposition December 2002, 30 (12) 1478-1483; DOI: https://doi.org/10.1124/dmd.30.12.1478
  4. Gibbs, Megan A.

    1. You have access
      Microsomal Protein Concentration Modifies the Apparent Inhibitory Potency of CYP3A Inhibitors
      Thanh Huu Tran, Lisa L. von Moltke, Karthik Venkatakrishnan, Brian W. Granda, Megan A. Gibbs, R. Scott Obach, Jerold S. Harmatz and David J. Greenblatt
      Drug Metabolism and Disposition December 2002, 30 (12) 1441-1445; DOI: https://doi.org/10.1124/dmd.30.12.1441
  5. Goodisman, Jerry

    1. You have access
      Kinetic Study of the Reaction of Cisplatin with Thiols
      James C. Dabrowiak, Jerry Goodisman and Abdul-Kader Souid
      Drug Metabolism and Disposition December 2002, 30 (12) 1378-1384; DOI: https://doi.org/10.1124/dmd.30.12.1378
  6. Granda, Brian W.

    1. You have access
      Microsomal Protein Concentration Modifies the Apparent Inhibitory Potency of CYP3A Inhibitors
      Thanh Huu Tran, Lisa L. von Moltke, Karthik Venkatakrishnan, Brian W. Granda, Megan A. Gibbs, R. Scott Obach, Jerold S. Harmatz and David J. Greenblatt
      Drug Metabolism and Disposition December 2002, 30 (12) 1441-1445; DOI: https://doi.org/10.1124/dmd.30.12.1441
  7. Greenblatt, David J.

    1. You have access
      Microsomal Protein Concentration Modifies the Apparent Inhibitory Potency of CYP3A Inhibitors
      Thanh Huu Tran, Lisa L. von Moltke, Karthik Venkatakrishnan, Brian W. Granda, Megan A. Gibbs, R. Scott Obach, Jerold S. Harmatz and David J. Greenblatt
      Drug Metabolism and Disposition December 2002, 30 (12) 1441-1445; DOI: https://doi.org/10.1124/dmd.30.12.1441
  8. Gustafsson, Lars L.

    1. You have access
      Enzyme Kinetics for the Formation of 3-Hydroxyquinine and Three New Metabolites of Quinine in Vitro; 3-Hydroxylation by CYP3A4 is Indeed the Major Metabolic Pathway
      Rajaa A. Mirghani, Ümit Yasar, Tao Zheng, James M. Cook, Lars L. Gustafsson, Gunnel Tybring and Örjan Ericsson
      Drug Metabolism and Disposition December 2002, 30 (12) 1368-1371; DOI: https://doi.org/10.1124/dmd.30.12.1368

H

  1. Halladay, Jason S.

    1. You have access
      Comparative Pharmacokinetic and Disposition Studies of [1-14C]1-Eicosanylcyclohexane, a Surrogate Mineral Hydrocarbon, in Female Fischer-344 and Sprague-Dawley Rats
      Jason S. Halladay, Carl R. Mackerer, Lorraine E. Twerdok and I. Glenn Sipes
      Drug Metabolism and Disposition December 2002, 30 (12) 1470-1477; DOI: https://doi.org/10.1124/dmd.30.12.1470
  2. Harmatz, Jerold S.

    1. You have access
      Microsomal Protein Concentration Modifies the Apparent Inhibitory Potency of CYP3A Inhibitors
      Thanh Huu Tran, Lisa L. von Moltke, Karthik Venkatakrishnan, Brian W. Granda, Megan A. Gibbs, R. Scott Obach, Jerold S. Harmatz and David J. Greenblatt
      Drug Metabolism and Disposition December 2002, 30 (12) 1441-1445; DOI: https://doi.org/10.1124/dmd.30.12.1441
  3. Hasegawa, Hiroshi

    1. You have access
      Kinetics of Sequential Metabolism from d-Leucine tol-Leucine via α-Ketoisocaproic Acid in Rat
      Hiroshi Hasegawa, Takehisa Matsukawa, Yoshihiko Shinohara and Takao Hashimoto
      Drug Metabolism and Disposition December 2002, 30 (12) 1436-1440; DOI: https://doi.org/10.1124/dmd.30.12.1436
  4. Hashimoto, Takao

    1. You have access
      Kinetics of Sequential Metabolism from d-Leucine tol-Leucine via α-Ketoisocaproic Acid in Rat
      Hiroshi Hasegawa, Takehisa Matsukawa, Yoshihiko Shinohara and Takao Hashimoto
      Drug Metabolism and Disposition December 2002, 30 (12) 1436-1440; DOI: https://doi.org/10.1124/dmd.30.12.1436
  5. Hasinoff, Brian B.

    1. You have access
      Dihydroorotase Catalyzes the Ring Opening of the Hydrolysis Intermediates of the Cardioprotective Drug Dexrazoxane (ICRF-187)
      Patricia E. Schroeder, Jeffrey N. Davidson and Brian B. Hasinoff
      Drug Metabolism and Disposition December 2002, 30 (12) 1431-1435; DOI: https://doi.org/10.1124/dmd.30.12.1431
  6. Hawes, Edward M.

    1. You have access
      Microsomal N-Glucuronidation of Nicotine and Cotinine: Human Hepatic Interindividual, Human Intertissue, and Interspecies Hepatic Variation
      Omar Ghosheh and Edward M. Hawes
      Drug Metabolism and Disposition December 2002, 30 (12) 1478-1483; DOI: https://doi.org/10.1124/dmd.30.12.1478
  7. Holmes, Elaine

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357
  8. Houston, J. Brian

    1. You have access
      Quinidine and Haloperidol as Modifiers of CYP3A4 Activity: Multisite Kinetic Model Approach
      Aleksandra Galetin, Stephen E. Clarke and J. Brian Houston
      Drug Metabolism and Disposition December 2002, 30 (12) 1512-1522; DOI: https://doi.org/10.1124/dmd.30.12.1512
  9. Hribar, Jeremy D.

    1. You have access
      Involvement of CYP3A in the Metabolism of Eplerenone in Humans and Dogs: Differential Metabolism by CYP3A4 and CYP3A5
      Chyung S. Cook, Loren M. Berry, David H. Kim, Earl G. Burton, Jeremy D. Hribar and Liming Zhang
      Drug Metabolism and Disposition December 2002, 30 (12) 1344-1351; DOI: https://doi.org/10.1124/dmd.30.12.1344
  10. Hu, Yiding

    1. You have access
      Enantioselective Metabolism of the Endocrine Disruptor Pesticide Methoxychlor by Human Cytochromes P450 (P450s): Major Differences in Selective Enantiomer Formation by Various P450 Isoforms
      Yiding Hu and David Kupfer
      Drug Metabolism and Disposition December 2002, 30 (12) 1329-1336; DOI: https://doi.org/10.1124/dmd.30.12.1329
  11. Huang, Jin-Ding

    1. You have access
      Pharmacokinetics of Midazolam and 1′-Hydroxymidazolam in Chinese with Different CYP3A5 Genotypes
      Pei-Shan Shih and Jin-Ding Huang
      Drug Metabolism and Disposition December 2002, 30 (12) 1491-1496; DOI: https://doi.org/10.1124/dmd.30.12.1491
  12. Huang, Shiew-Mei

    1. You have access
      Evaluation of Cytochrome P450 Probe Substrates Commonly Used by the Pharmaceutical Industry to Study in Vitro Drug Interactions
      Rae Yuan, Soraya Madani, Xiao-Xiong Wei, Kellie Reynolds and Shiew-Mei Huang
      Drug Metabolism and Disposition December 2002, 30 (12) 1311-1319; DOI: https://doi.org/10.1124/dmd.30.12.1311

I

  1. Inano, Keiko

    1. You have access
      Effects of Olopatadine, a New Antiallergic Agent, on Human Liver Microsomal Cytochrome P450 Activities
      Jiro Kajita, Keiko Inano, Eiichi Fuse, Takashi Kuwabara and Hiroyuki Kobayashi
      Drug Metabolism and Disposition December 2002, 30 (12) 1504-1511; DOI: https://doi.org/10.1124/dmd.30.12.1504
  2. Itose, Minoru

    1. You have access
      Mechanism for the Tissue Distribution of Grepafloxacin, a Fluoroquinolone Antibiotic, in Rats
      Takashi Suzuki, Yukio Kato, Hiroyuki Sasabe, Minoru Itose, Gohachiro Miyamoto and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2002, 30 (12) 1393-1399; DOI: https://doi.org/10.1124/dmd.30.12.1393

K

  1. Kajita, Jiro

    1. You have access
      Effects of Olopatadine, a New Antiallergic Agent, on Human Liver Microsomal Cytochrome P450 Activities
      Jiro Kajita, Keiko Inano, Eiichi Fuse, Takashi Kuwabara and Hiroyuki Kobayashi
      Drug Metabolism and Disposition December 2002, 30 (12) 1504-1511; DOI: https://doi.org/10.1124/dmd.30.12.1504
  2. Kato, Yukio

    1. You have access
      Mechanism for the Tissue Distribution of Grepafloxacin, a Fluoroquinolone Antibiotic, in Rats
      Takashi Suzuki, Yukio Kato, Hiroyuki Sasabe, Minoru Itose, Gohachiro Miyamoto and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2002, 30 (12) 1393-1399; DOI: https://doi.org/10.1124/dmd.30.12.1393
  3. Kellogg, G. E.

    1. You have access
      Irreversible Inhibition of CYP2D6 by (−)-Chloroephedrine, a Possible Impurity in Methamphetamine
      B. Rege, K. M. Carter, M. A. Sarkar, G. E. Kellogg and W. H. Soine
      Drug Metabolism and Disposition December 2002, 30 (12) 1337-1343; DOI: https://doi.org/10.1124/dmd.30.12.1337
  4. Kim, David H.

    1. You have access
      Involvement of CYP3A in the Metabolism of Eplerenone in Humans and Dogs: Differential Metabolism by CYP3A4 and CYP3A5
      Chyung S. Cook, Loren M. Berry, David H. Kim, Earl G. Burton, Jeremy D. Hribar and Liming Zhang
      Drug Metabolism and Disposition December 2002, 30 (12) 1344-1351; DOI: https://doi.org/10.1124/dmd.30.12.1344
  5. Kitamura, Shigeyuki

    1. You have access
      Deacylation of N-Arylformamides andN-Arylacetamides by Formamidase in Rat Liver
      Osamu Ueda, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2002, 30 (12) 1297-1299; DOI: https://doi.org/10.1124/dmd.30.12.1297
  6. Knol, James A.

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425
  7. Kobayashi, Hiroyuki

    1. You have access
      Effects of Olopatadine, a New Antiallergic Agent, on Human Liver Microsomal Cytochrome P450 Activities
      Jiro Kajita, Keiko Inano, Eiichi Fuse, Takashi Kuwabara and Hiroyuki Kobayashi
      Drug Metabolism and Disposition December 2002, 30 (12) 1504-1511; DOI: https://doi.org/10.1124/dmd.30.12.1504
  8. Kocarek, Thomas A.

    1. You have access
      Regulation of CYP2B6 and CYP3A Expression by Hydroxymethylglutaryl Coenzyme A Inhibitors in Primary Cultured Human Hepatocytes
      Thomas A. Kocarek, Michael S. Dahn, Hongbo Cai, Stephen C. Strom and Nancy A. Mercer-Haines
      Drug Metabolism and Disposition December 2002, 30 (12) 1400-1405; DOI: https://doi.org/10.1124/dmd.30.12.1400
  9. Kupfer, David

    1. You have access
      Enantioselective Metabolism of the Endocrine Disruptor Pesticide Methoxychlor by Human Cytochromes P450 (P450s): Major Differences in Selective Enantiomer Formation by Various P450 Isoforms
      Yiding Hu and David Kupfer
      Drug Metabolism and Disposition December 2002, 30 (12) 1329-1336; DOI: https://doi.org/10.1124/dmd.30.12.1329
  10. Kuwabara, Takashi

    1. You have access
      Effects of Olopatadine, a New Antiallergic Agent, on Human Liver Microsomal Cytochrome P450 Activities
      Jiro Kajita, Keiko Inano, Eiichi Fuse, Takashi Kuwabara and Hiroyuki Kobayashi
      Drug Metabolism and Disposition December 2002, 30 (12) 1504-1511; DOI: https://doi.org/10.1124/dmd.30.12.1504
  11. Kwon, Jun-Tack

    1. You have access
      Characterization of Nicotine and CotinineN-Glucuronidations in Human Liver Microsomes
      Miki Nakajima, Eriko Tanaka, Jun-Tack Kwon and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2002, 30 (12) 1484-1490; DOI: https://doi.org/10.1124/dmd.30.12.1484

L

  1. Lau, Yau Yi

    1. You have access
      Development of a Novel in Vitro Model to Predict Hepatic Clearance Using Fresh, Cryopreserved, and Sandwich-Cultured Hepatocytes
      Yau Yi Lau, Elpida Sapidou, Xiaoming Cui, Ronald E. White and K.-C. Cheng
      Drug Metabolism and Disposition December 2002, 30 (12) 1446-1454; DOI: https://doi.org/10.1124/dmd.30.12.1446
  2. Laus, G.

    1. You have access
      Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver Microsomes
      G. Elaut, G. Török, M. Vinken, G. Laus, P. Papeleu, D. Tourwe and V. Rogiers
      Drug Metabolism and Disposition December 2002, 30 (12) 1320-1328; DOI: https://doi.org/10.1124/dmd.30.12.1320
  3. Lee, Chunja

    1. You have access
      Suppression of Cytochrome P450 2C11 by Aromatic Hydrocarbons: Mechanistic Insights from Studies of the 5′-Flanking Region of theCYP2C11 Gene
      Anahita Bhathena, Chunja Lee and David S. Riddick
      Drug Metabolism and Disposition December 2002, 30 (12) 1385-1392; DOI: https://doi.org/10.1124/dmd.30.12.1385
  4. Lee, Su-Jun

    1. You have access
      Functional Properties of a Rainbow Trout CYP3A27 Expressed by Recombinant Baculovirus in Insect Cells
      Su-Jun Lee and Donald R. Buhler
      Drug Metabolism and Disposition December 2002, 30 (12) 1406-1412; DOI: https://doi.org/10.1124/dmd.30.12.1406
  5. Levi, Micha

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425
  6. Lu, Jian-Feng

    1. You have access
      Model-based Analysis of the Pharmacokinetic Interactions Between Ritonavir, Nelfinavir, and Saquinavir after Simultaneous and Staggered Oral Administration
      Jian-Feng Lu, Terrence F. Blaschke, Charles Flexner, Susan L. Rosenkranz, Lewis B. Sheiner and AIDS Clinical Trials Group Protocol 378 Investigators
      Drug Metabolism and Disposition December 2002, 30 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.30.12.1455
  7. Lunte, Susan M.

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425

M

  1. Mackerer, Carl R.

    1. You have access
      Comparative Pharmacokinetic and Disposition Studies of [1-14C]1-Eicosanylcyclohexane, a Surrogate Mineral Hydrocarbon, in Female Fischer-344 and Sprague-Dawley Rats
      Jason S. Halladay, Carl R. Mackerer, Lorraine E. Twerdok and I. Glenn Sipes
      Drug Metabolism and Disposition December 2002, 30 (12) 1470-1477; DOI: https://doi.org/10.1124/dmd.30.12.1470
  2. Madani, Soraya

    1. You have access
      Evaluation of Cytochrome P450 Probe Substrates Commonly Used by the Pharmaceutical Industry to Study in Vitro Drug Interactions
      Rae Yuan, Soraya Madani, Xiao-Xiong Wei, Kellie Reynolds and Shiew-Mei Huang
      Drug Metabolism and Disposition December 2002, 30 (12) 1311-1319; DOI: https://doi.org/10.1124/dmd.30.12.1311
  3. Matsukawa, Takehisa

    1. You have access
      Kinetics of Sequential Metabolism from d-Leucine tol-Leucine via α-Ketoisocaproic Acid in Rat
      Hiroshi Hasegawa, Takehisa Matsukawa, Yoshihiko Shinohara and Takao Hashimoto
      Drug Metabolism and Disposition December 2002, 30 (12) 1436-1440; DOI: https://doi.org/10.1124/dmd.30.12.1436
  4. Mercer-Haines, Nancy A.

    1. You have access
      Regulation of CYP2B6 and CYP3A Expression by Hydroxymethylglutaryl Coenzyme A Inhibitors in Primary Cultured Human Hepatocytes
      Thomas A. Kocarek, Michael S. Dahn, Hongbo Cai, Stephen C. Strom and Nancy A. Mercer-Haines
      Drug Metabolism and Disposition December 2002, 30 (12) 1400-1405; DOI: https://doi.org/10.1124/dmd.30.12.1400
  5. Mirghani, Rajaa A.

    1. You have access
      Enzyme Kinetics for the Formation of 3-Hydroxyquinine and Three New Metabolites of Quinine in Vitro; 3-Hydroxylation by CYP3A4 is Indeed the Major Metabolic Pathway
      Rajaa A. Mirghani, Ümit Yasar, Tao Zheng, James M. Cook, Lars L. Gustafsson, Gunnel Tybring and Örjan Ericsson
      Drug Metabolism and Disposition December 2002, 30 (12) 1368-1371; DOI: https://doi.org/10.1124/dmd.30.12.1368
  6. Miyamoto, Gohachiro

    1. You have access
      Mechanism for the Tissue Distribution of Grepafloxacin, a Fluoroquinolone Antibiotic, in Rats
      Takashi Suzuki, Yukio Kato, Hiroyuki Sasabe, Minoru Itose, Gohachiro Miyamoto and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2002, 30 (12) 1393-1399; DOI: https://doi.org/10.1124/dmd.30.12.1393
  7. Monte, Soria

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357

N

  1. Nakajima, Miki

    1. You have access
      Troglitazone Glucuronidation in Human Liver and Intestine Microsomes: High Catalytic Activity of UGT1A8 and UGT1A10
      Yuichiro Watanabe, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2002, 30 (12) 1462-1469; DOI: https://doi.org/10.1124/dmd.30.12.1462
    2. You have access
      Characterization of Nicotine and CotinineN-Glucuronidations in Human Liver Microsomes
      Miki Nakajima, Eriko Tanaka, Jun-Tack Kwon and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2002, 30 (12) 1484-1490; DOI: https://doi.org/10.1124/dmd.30.12.1484
  2. Neuvonen, Mikko

    1. You have access
      Gemfibrozil Inhibits CYP2C8-Mediated Cerivastatin Metabolism in Human Liver Microsomes
      Jun-Sheng Wang, Mikko Neuvonen, Xia Wen, Janne T. Backman and Pertti J. Neuvonen
      Drug Metabolism and Disposition December 2002, 30 (12) 1352-1356; DOI: https://doi.org/10.1124/dmd.30.12.1352
  3. Neuvonen, Pertti J.

    1. You have access
      Gemfibrozil Inhibits CYP2C8-Mediated Cerivastatin Metabolism in Human Liver Microsomes
      Jun-Sheng Wang, Mikko Neuvonen, Xia Wen, Janne T. Backman and Pertti J. Neuvonen
      Drug Metabolism and Disposition December 2002, 30 (12) 1352-1356; DOI: https://doi.org/10.1124/dmd.30.12.1352
  4. Nicholson, Jeremy K.

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357

O

  1. Obach, R. Scott

    1. You have access
      Microsomal Protein Concentration Modifies the Apparent Inhibitory Potency of CYP3A Inhibitors
      Thanh Huu Tran, Lisa L. von Moltke, Karthik Venkatakrishnan, Brian W. Granda, Megan A. Gibbs, R. Scott Obach, Jerold S. Harmatz and David J. Greenblatt
      Drug Metabolism and Disposition December 2002, 30 (12) 1441-1445; DOI: https://doi.org/10.1124/dmd.30.12.1441
  2. Ohta, Shigeru

    1. You have access
      Deacylation of N-Arylformamides andN-Arylacetamides by Formamidase in Rat Liver
      Osamu Ueda, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2002, 30 (12) 1297-1299; DOI: https://doi.org/10.1124/dmd.30.12.1297

P

  1. Papeleu, P.

    1. You have access
      Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver Microsomes
      G. Elaut, G. Török, M. Vinken, G. Laus, P. Papeleu, D. Tourwe and V. Rogiers
      Drug Metabolism and Disposition December 2002, 30 (12) 1320-1328; DOI: https://doi.org/10.1124/dmd.30.12.1320
  2. Payan, Jean-Paul

    1. You have access
      Toxicokinetics and Metabolism ofN-[14C]Methylpyrrolidone in Male Sprague-Dawley Rats. A Saturable NMP Elimination Process
      Jean-Paul Payan, Dominique Beydon, Jean-Paul Fabry, Isabelle Boudry, Benoit Cossec and Elisabeth Ferrari
      Drug Metabolism and Disposition December 2002, 30 (12) 1418-1424; DOI: https://doi.org/10.1124/dmd.30.12.1418

R

  1. Rege, B.

    1. You have access
      Irreversible Inhibition of CYP2D6 by (−)-Chloroephedrine, a Possible Impurity in Methamphetamine
      B. Rege, K. M. Carter, M. A. Sarkar, G. E. Kellogg and W. H. Soine
      Drug Metabolism and Disposition December 2002, 30 (12) 1337-1343; DOI: https://doi.org/10.1124/dmd.30.12.1337
  2. Reynolds, Kellie

    1. You have access
      Evaluation of Cytochrome P450 Probe Substrates Commonly Used by the Pharmaceutical Industry to Study in Vitro Drug Interactions
      Rae Yuan, Soraya Madani, Xiao-Xiong Wei, Kellie Reynolds and Shiew-Mei Huang
      Drug Metabolism and Disposition December 2002, 30 (12) 1311-1319; DOI: https://doi.org/10.1124/dmd.30.12.1311
  3. Riddick, David S.

    1. You have access
      Suppression of Cytochrome P450 2C11 by Aromatic Hydrocarbons: Mechanistic Insights from Studies of the 5′-Flanking Region of theCYP2C11 Gene
      Anahita Bhathena, Chunja Lee and David S. Riddick
      Drug Metabolism and Disposition December 2002, 30 (12) 1385-1392; DOI: https://doi.org/10.1124/dmd.30.12.1385
  4. Riley, Robert J.

    1. You have access
      The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties
      Rupert P. Austin, Patrick Barton, Scott L. Cockroft, Mark C. Wenlock and Robert J. Riley
      Drug Metabolism and Disposition December 2002, 30 (12) 1497-1503; DOI: https://doi.org/10.1124/dmd.30.12.1497
  5. Rios, Gladys R.

    1. You have access
      Inhibition and Active Sites of UDP-Glucuronosyltransferases 2B7 and 1A1.
      Gladys R. Rios and Thomas R. Tephly
      Drug Metabolism and Disposition December 2002, 30 (12) 1364-1367; DOI: https://doi.org/10.1124/dmd.30.12.1364
  6. Rogiers, V.

    1. You have access
      Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver Microsomes
      G. Elaut, G. Török, M. Vinken, G. Laus, P. Papeleu, D. Tourwe and V. Rogiers
      Drug Metabolism and Disposition December 2002, 30 (12) 1320-1328; DOI: https://doi.org/10.1124/dmd.30.12.1320
  7. Rosenkranz, Susan L.

    1. You have access
      Model-based Analysis of the Pharmacokinetic Interactions Between Ritonavir, Nelfinavir, and Saquinavir after Simultaneous and Staggered Oral Administration
      Jian-Feng Lu, Terrence F. Blaschke, Charles Flexner, Susan L. Rosenkranz, Lewis B. Sheiner and AIDS Clinical Trials Group Protocol 378 Investigators
      Drug Metabolism and Disposition December 2002, 30 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.30.12.1455

S

  1. Sapidou, Elpida

    1. You have access
      Development of a Novel in Vitro Model to Predict Hepatic Clearance Using Fresh, Cryopreserved, and Sandwich-Cultured Hepatocytes
      Yau Yi Lau, Elpida Sapidou, Xiaoming Cui, Ronald E. White and K.-C. Cheng
      Drug Metabolism and Disposition December 2002, 30 (12) 1446-1454; DOI: https://doi.org/10.1124/dmd.30.12.1446
  2. Sarkar, M. A.

    1. You have access
      Irreversible Inhibition of CYP2D6 by (−)-Chloroephedrine, a Possible Impurity in Methamphetamine
      B. Rege, K. M. Carter, M. A. Sarkar, G. E. Kellogg and W. H. Soine
      Drug Metabolism and Disposition December 2002, 30 (12) 1337-1343; DOI: https://doi.org/10.1124/dmd.30.12.1337
  3. Sasabe, Hiroyuki

    1. You have access
      Mechanism for the Tissue Distribution of Grepafloxacin, a Fluoroquinolone Antibiotic, in Rats
      Takashi Suzuki, Yukio Kato, Hiroyuki Sasabe, Minoru Itose, Gohachiro Miyamoto and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2002, 30 (12) 1393-1399; DOI: https://doi.org/10.1124/dmd.30.12.1393
  4. Schroeder, Patricia E.

    1. You have access
      Dihydroorotase Catalyzes the Ring Opening of the Hydrolysis Intermediates of the Cardioprotective Drug Dexrazoxane (ICRF-187)
      Patricia E. Schroeder, Jeffrey N. Davidson and Brian B. Hasinoff
      Drug Metabolism and Disposition December 2002, 30 (12) 1431-1435; DOI: https://doi.org/10.1124/dmd.30.12.1431
  5. Sharma, Rajendra

    1. You have access
      RLIP76, a Novel Transporter Catalyzing ATP-Dependent Efflux of Xenobiotics
      Sanjay Awasthi, Rajendra Sharma, Sharad S. Singhal, Piotr Zimniak and Yogesh C. Awasthi
      Drug Metabolism and Disposition December 2002, 30 (12) 1300-1310; DOI: https://doi.org/10.1124/dmd.30.12.1300
  6. Shaw, Leslie M.

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425
  7. Sheiner, Lewis B.

    1. You have access
      Model-based Analysis of the Pharmacokinetic Interactions Between Ritonavir, Nelfinavir, and Saquinavir after Simultaneous and Staggered Oral Administration
      Jian-Feng Lu, Terrence F. Blaschke, Charles Flexner, Susan L. Rosenkranz, Lewis B. Sheiner and AIDS Clinical Trials Group Protocol 378 Investigators
      Drug Metabolism and Disposition December 2002, 30 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.30.12.1455
  8. Shih, Pei-Shan

    1. You have access
      Pharmacokinetics of Midazolam and 1′-Hydroxymidazolam in Chinese with Different CYP3A5 Genotypes
      Pei-Shan Shih and Jin-Ding Huang
      Drug Metabolism and Disposition December 2002, 30 (12) 1491-1496; DOI: https://doi.org/10.1124/dmd.30.12.1491
  9. Shinohara, Yoshihiko

    1. You have access
      Kinetics of Sequential Metabolism from d-Leucine tol-Leucine via α-Ketoisocaproic Acid in Rat
      Hiroshi Hasegawa, Takehisa Matsukawa, Yoshihiko Shinohara and Takao Hashimoto
      Drug Metabolism and Disposition December 2002, 30 (12) 1436-1440; DOI: https://doi.org/10.1124/dmd.30.12.1436
  10. Singhal, Sharad S.

    1. You have access
      RLIP76, a Novel Transporter Catalyzing ATP-Dependent Efflux of Xenobiotics
      Sanjay Awasthi, Rajendra Sharma, Sharad S. Singhal, Piotr Zimniak and Yogesh C. Awasthi
      Drug Metabolism and Disposition December 2002, 30 (12) 1300-1310; DOI: https://doi.org/10.1124/dmd.30.12.1300
  11. Sipes, I. Glenn

    1. You have access
      Comparative Pharmacokinetic and Disposition Studies of [1-14C]1-Eicosanylcyclohexane, a Surrogate Mineral Hydrocarbon, in Female Fischer-344 and Sprague-Dawley Rats
      Jason S. Halladay, Carl R. Mackerer, Lorraine E. Twerdok and I. Glenn Sipes
      Drug Metabolism and Disposition December 2002, 30 (12) 1470-1477; DOI: https://doi.org/10.1124/dmd.30.12.1470
  12. Slattery, John T.

    1. You have access
      Effects of Ethanol Dose and Ethanol Withdrawal on Rat Liver Mitochondrial Glutathione: Implication of Potentiated Acetaminophen Toxicity in Alcoholics
      Ping Zhao and John T. Slattery
      Drug Metabolism and Disposition December 2002, 30 (12) 1413-1417; DOI: https://doi.org/10.1124/dmd.30.12.1413
  13. Smith, David E.

    1. You have access
      Regional Pharmacokinetics of Amifostine in Anesthetized Dogs: Role of the Liver, Gastrointestinal Tract, Lungs, and Kidneys
      Micha Levi, James A. Knol, William D. Ensminger, Susan J. DeRemer, Chunzhi Dou, Susan M. Lunte, Heather S. Bonner, Leslie M. Shaw and David E. Smith
      Drug Metabolism and Disposition December 2002, 30 (12) 1425-1430; DOI: https://doi.org/10.1124/dmd.30.12.1425
  14. Soine, W. H.

    1. You have access
      Irreversible Inhibition of CYP2D6 by (−)-Chloroephedrine, a Possible Impurity in Methamphetamine
      B. Rege, K. M. Carter, M. A. Sarkar, G. E. Kellogg and W. H. Soine
      Drug Metabolism and Disposition December 2002, 30 (12) 1337-1343; DOI: https://doi.org/10.1124/dmd.30.12.1337
  15. Souid, Abdul-Kader

    1. You have access
      Kinetic Study of the Reaction of Cisplatin with Thiols
      James C. Dabrowiak, Jerry Goodisman and Abdul-Kader Souid
      Drug Metabolism and Disposition December 2002, 30 (12) 1378-1384; DOI: https://doi.org/10.1124/dmd.30.12.1378
  16. Strom, Stephen C.

    1. You have access
      Regulation of CYP2B6 and CYP3A Expression by Hydroxymethylglutaryl Coenzyme A Inhibitors in Primary Cultured Human Hepatocytes
      Thomas A. Kocarek, Michael S. Dahn, Hongbo Cai, Stephen C. Strom and Nancy A. Mercer-Haines
      Drug Metabolism and Disposition December 2002, 30 (12) 1400-1405; DOI: https://doi.org/10.1124/dmd.30.12.1400
  17. Sugiyama, Yuichi

    1. You have access
      Mechanism for the Tissue Distribution of Grepafloxacin, a Fluoroquinolone Antibiotic, in Rats
      Takashi Suzuki, Yukio Kato, Hiroyuki Sasabe, Minoru Itose, Gohachiro Miyamoto and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2002, 30 (12) 1393-1399; DOI: https://doi.org/10.1124/dmd.30.12.1393
  18. Suzuki, Takashi

    1. You have access
      Mechanism for the Tissue Distribution of Grepafloxacin, a Fluoroquinolone Antibiotic, in Rats
      Takashi Suzuki, Yukio Kato, Hiroyuki Sasabe, Minoru Itose, Gohachiro Miyamoto and Yuichi Sugiyama
      Drug Metabolism and Disposition December 2002, 30 (12) 1393-1399; DOI: https://doi.org/10.1124/dmd.30.12.1393

T

  1. Tanaka, Eriko

    1. You have access
      Characterization of Nicotine and CotinineN-Glucuronidations in Human Liver Microsomes
      Miki Nakajima, Eriko Tanaka, Jun-Tack Kwon and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2002, 30 (12) 1484-1490; DOI: https://doi.org/10.1124/dmd.30.12.1484
  2. Tephly, Thomas R.

    1. You have access
      Inhibition and Active Sites of UDP-Glucuronosyltransferases 2B7 and 1A1.
      Gladys R. Rios and Thomas R. Tephly
      Drug Metabolism and Disposition December 2002, 30 (12) 1364-1367; DOI: https://doi.org/10.1124/dmd.30.12.1364
  3. Török, G.

    1. You have access
      Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver Microsomes
      G. Elaut, G. Török, M. Vinken, G. Laus, P. Papeleu, D. Tourwe and V. Rogiers
      Drug Metabolism and Disposition December 2002, 30 (12) 1320-1328; DOI: https://doi.org/10.1124/dmd.30.12.1320
  4. Tourwe, D.

    1. You have access
      Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver Microsomes
      G. Elaut, G. Török, M. Vinken, G. Laus, P. Papeleu, D. Tourwe and V. Rogiers
      Drug Metabolism and Disposition December 2002, 30 (12) 1320-1328; DOI: https://doi.org/10.1124/dmd.30.12.1320
  5. Tran, Thanh Huu

    1. You have access
      Microsomal Protein Concentration Modifies the Apparent Inhibitory Potency of CYP3A Inhibitors
      Thanh Huu Tran, Lisa L. von Moltke, Karthik Venkatakrishnan, Brian W. Granda, Megan A. Gibbs, R. Scott Obach, Jerold S. Harmatz and David J. Greenblatt
      Drug Metabolism and Disposition December 2002, 30 (12) 1441-1445; DOI: https://doi.org/10.1124/dmd.30.12.1441
  6. Troke, Jeff

    1. You have access
      Application of Directly Coupled High Performance Liquid Chromatography-NMR-Mass Spectometry and 1H NMR Spectroscopic Studies to the Investigation of 2,3-Benzofuran Metabolism in Sprague-Dawley Rats
      John C. Connelly, Susan C. Connor, Soria Monte, Nigel J.C. Bailey, Nathan Borgeaud, Elaine Holmes, Jeff Troke, Jeremy K. Nicholson and Claire L. Gavaghan
      Drug Metabolism and Disposition December 2002, 30 (12) 1357-1363; DOI: https://doi.org/10.1124/dmd.30.12.1357
  7. Twerdok, Lorraine E.

    1. You have access
      Comparative Pharmacokinetic and Disposition Studies of [1-14C]1-Eicosanylcyclohexane, a Surrogate Mineral Hydrocarbon, in Female Fischer-344 and Sprague-Dawley Rats
      Jason S. Halladay, Carl R. Mackerer, Lorraine E. Twerdok and I. Glenn Sipes
      Drug Metabolism and Disposition December 2002, 30 (12) 1470-1477; DOI: https://doi.org/10.1124/dmd.30.12.1470
  8. Tybring, Gunnel

    1. You have access
      Enzyme Kinetics for the Formation of 3-Hydroxyquinine and Three New Metabolites of Quinine in Vitro; 3-Hydroxylation by CYP3A4 is Indeed the Major Metabolic Pathway
      Rajaa A. Mirghani, Ümit Yasar, Tao Zheng, James M. Cook, Lars L. Gustafsson, Gunnel Tybring and Örjan Ericsson
      Drug Metabolism and Disposition December 2002, 30 (12) 1368-1371; DOI: https://doi.org/10.1124/dmd.30.12.1368

U

  1. Uckun, Fatih M.

    1. You have access
      Metabolism of Stavudine-5′-[p-Bromophenyl Methoxyalaninyl Phosphate], Stampidine, in Mice, Dogs, and Cats
      Chun-Lin Chen, Gengli Yu, T. K. Venkatachalam and Fatih M. Uckun
      Drug Metabolism and Disposition December 2002, 30 (12) 1523-1531; DOI: https://doi.org/10.1124/dmd.30.12.1523
  2. Ueda, Osamu

    1. You have access
      Deacylation of N-Arylformamides andN-Arylacetamides by Formamidase in Rat Liver
      Osamu Ueda, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2002, 30 (12) 1297-1299; DOI: https://doi.org/10.1124/dmd.30.12.1297

V

  1. Venkatachalam, T. K.

    1. You have access
      Metabolism of Stavudine-5′-[p-Bromophenyl Methoxyalaninyl Phosphate], Stampidine, in Mice, Dogs, and Cats
      Chun-Lin Chen, Gengli Yu, T. K. Venkatachalam and Fatih M. Uckun
      Drug Metabolism and Disposition December 2002, 30 (12) 1523-1531; DOI: https://doi.org/10.1124/dmd.30.12.1523
  2. Venkatakrishnan, Karthik

    1. You have access
      Microsomal Protein Concentration Modifies the Apparent Inhibitory Potency of CYP3A Inhibitors
      Thanh Huu Tran, Lisa L. von Moltke, Karthik Venkatakrishnan, Brian W. Granda, Megan A. Gibbs, R. Scott Obach, Jerold S. Harmatz and David J. Greenblatt
      Drug Metabolism and Disposition December 2002, 30 (12) 1441-1445; DOI: https://doi.org/10.1124/dmd.30.12.1441
  3. Vinken, M.

    1. You have access
      Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver Microsomes
      G. Elaut, G. Török, M. Vinken, G. Laus, P. Papeleu, D. Tourwe and V. Rogiers
      Drug Metabolism and Disposition December 2002, 30 (12) 1320-1328; DOI: https://doi.org/10.1124/dmd.30.12.1320
  4. von Moltke, Lisa L.

    1. You have access
      Microsomal Protein Concentration Modifies the Apparent Inhibitory Potency of CYP3A Inhibitors
      Thanh Huu Tran, Lisa L. von Moltke, Karthik Venkatakrishnan, Brian W. Granda, Megan A. Gibbs, R. Scott Obach, Jerold S. Harmatz and David J. Greenblatt
      Drug Metabolism and Disposition December 2002, 30 (12) 1441-1445; DOI: https://doi.org/10.1124/dmd.30.12.1441

W

  1. Wang, Jun-Sheng

    1. You have access
      Gemfibrozil Inhibits CYP2C8-Mediated Cerivastatin Metabolism in Human Liver Microsomes
      Jun-Sheng Wang, Mikko Neuvonen, Xia Wen, Janne T. Backman and Pertti J. Neuvonen
      Drug Metabolism and Disposition December 2002, 30 (12) 1352-1356; DOI: https://doi.org/10.1124/dmd.30.12.1352
  2. Watanabe, Yuichiro

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      Troglitazone Glucuronidation in Human Liver and Intestine Microsomes: High Catalytic Activity of UGT1A8 and UGT1A10
      Yuichiro Watanabe, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2002, 30 (12) 1462-1469; DOI: https://doi.org/10.1124/dmd.30.12.1462
  3. Wei, Xiao-Xiong

    1. You have access
      Evaluation of Cytochrome P450 Probe Substrates Commonly Used by the Pharmaceutical Industry to Study in Vitro Drug Interactions
      Rae Yuan, Soraya Madani, Xiao-Xiong Wei, Kellie Reynolds and Shiew-Mei Huang
      Drug Metabolism and Disposition December 2002, 30 (12) 1311-1319; DOI: https://doi.org/10.1124/dmd.30.12.1311
  4. Wen, Xia

    1. You have access
      Gemfibrozil Inhibits CYP2C8-Mediated Cerivastatin Metabolism in Human Liver Microsomes
      Jun-Sheng Wang, Mikko Neuvonen, Xia Wen, Janne T. Backman and Pertti J. Neuvonen
      Drug Metabolism and Disposition December 2002, 30 (12) 1352-1356; DOI: https://doi.org/10.1124/dmd.30.12.1352
  5. Wenlock, Mark C.

    1. You have access
      The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties
      Rupert P. Austin, Patrick Barton, Scott L. Cockroft, Mark C. Wenlock and Robert J. Riley
      Drug Metabolism and Disposition December 2002, 30 (12) 1497-1503; DOI: https://doi.org/10.1124/dmd.30.12.1497
  6. White, Ronald E.

    1. You have access
      Development of a Novel in Vitro Model to Predict Hepatic Clearance Using Fresh, Cryopreserved, and Sandwich-Cultured Hepatocytes
      Yau Yi Lau, Elpida Sapidou, Xiaoming Cui, Ronald E. White and K.-C. Cheng
      Drug Metabolism and Disposition December 2002, 30 (12) 1446-1454; DOI: https://doi.org/10.1124/dmd.30.12.1446
  7. Wienkers, Larry C.

    1. You have access
      Multiple Cytochrome P450 Enzymes Responsible for the Oxidative Metabolism of the Substituted (S)-3-Phenylpiperidine, (S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine Hydrochloride, in Human Liver Microsomes
      Larry C. Wienkers and Michael A. Wynalda
      Drug Metabolism and Disposition December 2002, 30 (12) 1372-1377; DOI: https://doi.org/10.1124/dmd.30.12.1372
  8. Wynalda, Michael A.

    1. You have access
      Multiple Cytochrome P450 Enzymes Responsible for the Oxidative Metabolism of the Substituted (S)-3-Phenylpiperidine, (S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine Hydrochloride, in Human Liver Microsomes
      Larry C. Wienkers and Michael A. Wynalda
      Drug Metabolism and Disposition December 2002, 30 (12) 1372-1377; DOI: https://doi.org/10.1124/dmd.30.12.1372

Y

  1. Yasar, Ümit

    1. You have access
      Enzyme Kinetics for the Formation of 3-Hydroxyquinine and Three New Metabolites of Quinine in Vitro; 3-Hydroxylation by CYP3A4 is Indeed the Major Metabolic Pathway
      Rajaa A. Mirghani, Ümit Yasar, Tao Zheng, James M. Cook, Lars L. Gustafsson, Gunnel Tybring and Örjan Ericsson
      Drug Metabolism and Disposition December 2002, 30 (12) 1368-1371; DOI: https://doi.org/10.1124/dmd.30.12.1368
  2. Yokoi, Tsuyoshi

    1. You have access
      Troglitazone Glucuronidation in Human Liver and Intestine Microsomes: High Catalytic Activity of UGT1A8 and UGT1A10
      Yuichiro Watanabe, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2002, 30 (12) 1462-1469; DOI: https://doi.org/10.1124/dmd.30.12.1462
    2. You have access
      Characterization of Nicotine and CotinineN-Glucuronidations in Human Liver Microsomes
      Miki Nakajima, Eriko Tanaka, Jun-Tack Kwon and Tsuyoshi Yokoi
      Drug Metabolism and Disposition December 2002, 30 (12) 1484-1490; DOI: https://doi.org/10.1124/dmd.30.12.1484
  3. Yu, Gengli

    1. You have access
      Metabolism of Stavudine-5′-[p-Bromophenyl Methoxyalaninyl Phosphate], Stampidine, in Mice, Dogs, and Cats
      Chun-Lin Chen, Gengli Yu, T. K. Venkatachalam and Fatih M. Uckun
      Drug Metabolism and Disposition December 2002, 30 (12) 1523-1531; DOI: https://doi.org/10.1124/dmd.30.12.1523
  4. Yuan, Rae

    1. You have access
      Evaluation of Cytochrome P450 Probe Substrates Commonly Used by the Pharmaceutical Industry to Study in Vitro Drug Interactions
      Rae Yuan, Soraya Madani, Xiao-Xiong Wei, Kellie Reynolds and Shiew-Mei Huang
      Drug Metabolism and Disposition December 2002, 30 (12) 1311-1319; DOI: https://doi.org/10.1124/dmd.30.12.1311

Z

  1. Zhang, Liming

    1. You have access
      Involvement of CYP3A in the Metabolism of Eplerenone in Humans and Dogs: Differential Metabolism by CYP3A4 and CYP3A5
      Chyung S. Cook, Loren M. Berry, David H. Kim, Earl G. Burton, Jeremy D. Hribar and Liming Zhang
      Drug Metabolism and Disposition December 2002, 30 (12) 1344-1351; DOI: https://doi.org/10.1124/dmd.30.12.1344
  2. Zhao, Ping

    1. You have access
      Effects of Ethanol Dose and Ethanol Withdrawal on Rat Liver Mitochondrial Glutathione: Implication of Potentiated Acetaminophen Toxicity in Alcoholics
      Ping Zhao and John T. Slattery
      Drug Metabolism and Disposition December 2002, 30 (12) 1413-1417; DOI: https://doi.org/10.1124/dmd.30.12.1413
  3. Zheng, Tao

    1. You have access
      Enzyme Kinetics for the Formation of 3-Hydroxyquinine and Three New Metabolites of Quinine in Vitro; 3-Hydroxylation by CYP3A4 is Indeed the Major Metabolic Pathway
      Rajaa A. Mirghani, Ümit Yasar, Tao Zheng, James M. Cook, Lars L. Gustafsson, Gunnel Tybring and Örjan Ericsson
      Drug Metabolism and Disposition December 2002, 30 (12) 1368-1371; DOI: https://doi.org/10.1124/dmd.30.12.1368
  4. Zimniak, Piotr

    1. You have access
      RLIP76, a Novel Transporter Catalyzing ATP-Dependent Efflux of Xenobiotics
      Sanjay Awasthi, Rajendra Sharma, Sharad S. Singhal, Piotr Zimniak and Yogesh C. Awasthi
      Drug Metabolism and Disposition December 2002, 30 (12) 1300-1310; DOI: https://doi.org/10.1124/dmd.30.12.1300
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Drug Metabolism and Disposition: 30 (12)
Drug Metabolism and Disposition
Vol. 30, Issue 12
1 Dec 2002
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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