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Research ArticleArticle

Model-based Analysis of the Pharmacokinetic Interactions Between Ritonavir, Nelfinavir, and Saquinavir after Simultaneous and Staggered Oral Administration

Jian-Feng Lu, Terrence F. Blaschke, Charles Flexner, Susan L. Rosenkranz, Lewis B. Sheiner and AIDS Clinical Trials Group Protocol 378 Investigators
Drug Metabolism and Disposition December 2002, 30 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.30.12.1455

Article Information

vol. 30 no. 12 1455-1461
DOI 
https://doi.org/10.1124/dmd.30.12.1455
PubMed 
12433819
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 7, 2002
  • Accepted August 15, 2002
  • Published online December 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jian-Feng Lu1,2,
  2. Terrence F. Blaschke3,
  3. Charles Flexner4,
  4. Susan L. Rosenkranz5,
  5. Lewis B. Sheiner and
  6. AIDS Clinical Trials Group Protocol 378 Investigators
  1. 1Department of Laboratory Medicine and Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California (J.-F.L., L.B.S.); 2Department of Experimental and Clinical Pharmacology, Genentech, Inc., South San Francisco, California (J.-F.L.); 3Department of Medicine, Division of Clinical Pharmacology, Stanford University Medical Center, Stanford, California (T.F.B.); 4Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland (C.F.); and 5Statistics and Data Analysis Center, AIDs Clinical Trials Group/Harvard School of Public Health, Boston, Massachusetts (S.L.R.).
  1. Lewis B. Sheiner, Box 0626, UCSF, CA 94143-0626. E-mail: lbs{at}c255.ucsf.edu
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Research ArticleArticle

Model-based Analysis of the Pharmacokinetic Interactions Between Ritonavir, Nelfinavir, and Saquinavir after Simultaneous and Staggered Oral Administration

Jian-Feng Lu, Terrence F. Blaschke, Charles Flexner, Susan L. Rosenkranz, Lewis B. Sheiner and AIDS Clinical Trials Group Protocol 378 Investigators
Drug Metabolism and Disposition December 1, 2002, 30 (12) 1455-1461; DOI: https://doi.org/10.1124/dmd.30.12.1455
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