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Research ArticleArticle

Quinidine and Haloperidol as Modifiers of CYP3A4 Activity: Multisite Kinetic Model Approach

Aleksandra Galetin, Stephen E. Clarke and J. Brian Houston
Drug Metabolism and Disposition December 2002, 30 (12) 1512-1522; DOI: https://doi.org/10.1124/dmd.30.12.1512

Article Information

vol. 30 no. 12 1512-1522
DOI 
https://doi.org/10.1124/dmd.30.12.1512
PubMed 
12433827
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 9, 2002
  • Accepted September 9, 2002
  • Published online December 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Aleksandra Galetin1,
  2. Stephen E. Clarke2 and
  3. J. Brian Houston1
  1. 1School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom (A.G., J.B.H.); and 2Department of Mechanism and Extrapolation Technologies, GlaxoSmithKline, Welwyn, Hertfordshire, United Kingdom (S.E.C.)
  1. Dr. J. B. Houston, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Rd., Manchester, M13 9PL, UK. E-mail:brian.houston{at}man.ac.uk
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Research ArticleArticle

Quinidine and Haloperidol as Modifiers of CYP3A4 Activity: Multisite Kinetic Model Approach

Aleksandra Galetin, Stephen E. Clarke and J. Brian Houston
Drug Metabolism and Disposition December 1, 2002, 30 (12) 1512-1522; DOI: https://doi.org/10.1124/dmd.30.12.1512
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