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Index by author

April 01, 2002; Volume 30,Issue 4

A

  1. Acheampong, Andrew A.

    1. Distribution of Brimonidine into Anterior and Posterior Tissues of Monkey, Rabbit, and Rat Eyes
      Andrew A. Acheampong, Martha Shackleton, Brian John, James Burke, Larry Wheeler and Diane Tang-Liu
      Drug Metabolism and Disposition April 2002, 30 (4) 421-429; DOI: https://doi.org/10.1124/dmd.30.4.421

  2. Affrime, Melton

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  3. Alton, Kevin B.

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  4. Alvarez, Ana I.

    1. The Anthelminthic Agent Albendazole Does Not Interact with P-Glycoprotein
      Gracia Merino, Ana I. Alvarez, Julio G. Prieto and Richard B. Kim
      Drug Metabolism and Disposition April 2002, 30 (4) 365-369; DOI: https://doi.org/10.1124/dmd.30.4.365

  5. Alvinerie, Paul

    1. Regioselective Metabolism of Taxoids by Human CYP3A4 and 2C8: Structure-Activity Relationship
      Thierry Cresteil, Bernard Monsarrat, Joelle Dubois, Michelle Sonnier, Paul Alvinerie and Françoise Gueritte
      Drug Metabolism and Disposition April 2002, 30 (4) 438-445; DOI: https://doi.org/10.1124/dmd.30.4.438

  6. Ando, Masanori

    1. Interaction of Irinotecan (CPT-11) and Its Active Metabolite 7-Ethyl-10-Hydroxycamptothecin (SN-38) with Human Cytochrome P450 Enzymes
      Nobumitsu Hanioka, Shogo Ozawa, Hideto Jinno, Toshiko Tanaka-Kagawa, Tetsuji Nishimura, Masanori Ando and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 391-396; DOI: https://doi.org/10.1124/dmd.30.4.391

B

  1. Benetton, Salete A.

    1. In Vitro Effect of Standardized Ginseng Extracts and Individual Ginsenosides on the Catalytic Activity of Human CYP1A1, CYP1A2, and CYP1B1
      Thomas K. H. Chang, Jie Chen and Salete A. Benetton
      Drug Metabolism and Disposition April 2002, 30 (4) 378-384; DOI: https://doi.org/10.1124/dmd.30.4.378

  2. Bolze, Sebastien

    1. Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin
      Sebastien Bolze, Norbert Bromet, Croisine Gay-Feutry, Frederic Massiere, Roselyne Boulieu and Thierry Hulot
      Drug Metabolism and Disposition April 2002, 30 (4) 404-413; DOI: https://doi.org/10.1124/dmd.30.4.404

  3. Boulieu, Roselyne

    1. Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin
      Sebastien Bolze, Norbert Bromet, Croisine Gay-Feutry, Frederic Massiere, Roselyne Boulieu and Thierry Hulot
      Drug Metabolism and Disposition April 2002, 30 (4) 404-413; DOI: https://doi.org/10.1124/dmd.30.4.404

  4. Bromet, Norbert

    1. Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin
      Sebastien Bolze, Norbert Bromet, Croisine Gay-Feutry, Frederic Massiere, Roselyne Boulieu and Thierry Hulot
      Drug Metabolism and Disposition April 2002, 30 (4) 404-413; DOI: https://doi.org/10.1124/dmd.30.4.404

  5. Burke, James

    1. Distribution of Brimonidine into Anterior and Posterior Tissues of Monkey, Rabbit, and Rat Eyes
      Andrew A. Acheampong, Martha Shackleton, Brian John, James Burke, Larry Wheeler and Diane Tang-Liu
      Drug Metabolism and Disposition April 2002, 30 (4) 421-429; DOI: https://doi.org/10.1124/dmd.30.4.421

C

  1. Cayen, Mitchell N.

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  2. Chang, Thomas K. H.

    1. In Vitro Effect of Standardized Ginseng Extracts and Individual Ginsenosides on the Catalytic Activity of Human CYP1A1, CYP1A2, and CYP1B1
      Thomas K. H. Chang, Jie Chen and Salete A. Benetton
      Drug Metabolism and Disposition April 2002, 30 (4) 378-384; DOI: https://doi.org/10.1124/dmd.30.4.378

  3. Chen, Jie

    1. In Vitro Effect of Standardized Ginseng Extracts and Individual Ginsenosides on the Catalytic Activity of Human CYP1A1, CYP1A2, and CYP1B1
      Thomas K. H. Chang, Jie Chen and Salete A. Benetton
      Drug Metabolism and Disposition April 2002, 30 (4) 378-384; DOI: https://doi.org/10.1124/dmd.30.4.378

  4. Chowdhury, Swapan

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  5. Coop, Leslie

    1. Determination of Acetaminophen-Protein Adducts in Mouse Liver and Serum and Human Serum after Hepatotoxic Doses of Acetaminophen Using High-Performance Liquid Chromatography with Electrochemical Detection
      Kenneth L. Muldrew, Laura P. James, Leslie Coop, Sandra S. McCullough, Howard P. Hendrickson, Jack A. Hinson and Philip R. Mayeux
      Drug Metabolism and Disposition April 2002, 30 (4) 446-451; DOI: https://doi.org/10.1124/dmd.30.4.446

  6. Cresteil, Thierry

    1. Regioselective Metabolism of Taxoids by Human CYP3A4 and 2C8: Structure-Activity Relationship
      Thierry Cresteil, Bernard Monsarrat, Joelle Dubois, Michelle Sonnier, Paul Alvinerie and Françoise Gueritte
      Drug Metabolism and Disposition April 2002, 30 (4) 438-445; DOI: https://doi.org/10.1124/dmd.30.4.438

D

  1. Dickmann, Leslie J.

    1. Polymorphic Variants (CYP2C9*3 and CYP2C9*5) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles
      Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Allan E. Rettie, Matthew A. Hummel and Leslie J. Dickmann
      Drug Metabolism and Disposition April 2002, 30 (4) 385-390; DOI: https://doi.org/10.1124/dmd.30.4.385

  2. Dubois, Joelle

    1. Regioselective Metabolism of Taxoids by Human CYP3A4 and 2C8: Structure-Activity Relationship
      Thierry Cresteil, Bernard Monsarrat, Joelle Dubois, Michelle Sonnier, Paul Alvinerie and Françoise Gueritte
      Drug Metabolism and Disposition April 2002, 30 (4) 438-445; DOI: https://doi.org/10.1124/dmd.30.4.438

E

  1. Ehninger, Gerhard

    1. The Oxidative Biotransformation of Losoxantrone (CI-941)
      Ulf D. Renner, Georgios Piperopoulos, Rolf Gebhardt, Gerhard Ehninger and Klaus-Peter Zeller
      Drug Metabolism and Disposition April 2002, 30 (4) 464-478; DOI: https://doi.org/10.1124/dmd.30.4.464

F

  1. Fang, Jia-Long

    1. Glucuronidation: An Important Mechanism for Detoxification of Benzo[a]Pyrene Metabolites in Aerodigestive Tract Tissues
      Zhong Zheng, Jia-Long Fang and Philip Lazarus
      Drug Metabolism and Disposition April 2002, 30 (4) 397-403; DOI: https://doi.org/10.1124/dmd.30.4.397

  2. Fowler, Stephen M.

    1. CYP3A4 Active Site Volume Modification by Mutagenesis of Leucine 211
      Stephen M. Fowler, John M. Taylor, Thomas Friedberg, C. Roland Wolf and Robert J. Riley
      Drug Metabolism and Disposition April 2002, 30 (4) 452-456; DOI: https://doi.org/10.1124/dmd.30.4.452

  3. Friedberg, Thomas

    1. CYP3A4 Active Site Volume Modification by Mutagenesis of Leucine 211
      Stephen M. Fowler, John M. Taylor, Thomas Friedberg, C. Roland Wolf and Robert J. Riley
      Drug Metabolism and Disposition April 2002, 30 (4) 452-456; DOI: https://doi.org/10.1124/dmd.30.4.452

G

  1. Gay-Feutry, Croisine

    1. Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin
      Sebastien Bolze, Norbert Bromet, Croisine Gay-Feutry, Frederic Massiere, Roselyne Boulieu and Thierry Hulot
      Drug Metabolism and Disposition April 2002, 30 (4) 404-413; DOI: https://doi.org/10.1124/dmd.30.4.404

  2. Gebhardt, Rolf

    1. The Oxidative Biotransformation of Losoxantrone (CI-941)
      Ulf D. Renner, Georgios Piperopoulos, Rolf Gebhardt, Gerhard Ehninger and Klaus-Peter Zeller
      Drug Metabolism and Disposition April 2002, 30 (4) 464-478; DOI: https://doi.org/10.1124/dmd.30.4.464

  3. Gueritte, Françoise

    1. Regioselective Metabolism of Taxoids by Human CYP3A4 and 2C8: Structure-Activity Relationship
      Thierry Cresteil, Bernard Monsarrat, Joelle Dubois, Michelle Sonnier, Paul Alvinerie and Françoise Gueritte
      Drug Metabolism and Disposition April 2002, 30 (4) 438-445; DOI: https://doi.org/10.1124/dmd.30.4.438

  4. Guo, Ailan

    1. Delineating the Contribution of Secretory Transporters in the Efflux of Etoposide Using Madin-Darby Canine Kidney (MDCK) Cells Overexpressing P-Glycoprotein (Pgp), Multidrug Resistance-Associated Protein (MRP1), and Canalicular Multispecific Organic Anion Transporter (cMOAT)
      Ailan Guo, William Marinaro, Peidi Hu and Patrick J. Sinko
      Drug Metabolism and Disposition April 2002, 30 (4) 457-463; DOI: https://doi.org/10.1124/dmd.30.4.457

H

  1. Haining, Robert L.

    1. Polymorphic Variants (CYP2C9*3 and CYP2C9*5) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles
      Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Allan E. Rettie, Matthew A. Hummel and Leslie J. Dickmann
      Drug Metabolism and Disposition April 2002, 30 (4) 385-390; DOI: https://doi.org/10.1124/dmd.30.4.385

  2. Hanioka, Nobumitsu

    1. Interaction of Irinotecan (CPT-11) and Its Active Metabolite 7-Ethyl-10-Hydroxycamptothecin (SN-38) with Human Cytochrome P450 Enzymes
      Nobumitsu Hanioka, Shogo Ozawa, Hideto Jinno, Toshiko Tanaka-Kagawa, Tetsuji Nishimura, Masanori Ando and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 391-396; DOI: https://doi.org/10.1124/dmd.30.4.391

  3. Hendrickson, Howard P.

    1. Determination of Acetaminophen-Protein Adducts in Mouse Liver and Serum and Human Serum after Hepatotoxic Doses of Acetaminophen Using High-Performance Liquid Chromatography with Electrochemical Detection
      Kenneth L. Muldrew, Laura P. James, Leslie Coop, Sandra S. McCullough, Howard P. Hendrickson, Jack A. Hinson and Philip R. Mayeux
      Drug Metabolism and Disposition April 2002, 30 (4) 446-451; DOI: https://doi.org/10.1124/dmd.30.4.446

  4. Hinson, Jack A.

    1. Determination of Acetaminophen-Protein Adducts in Mouse Liver and Serum and Human Serum after Hepatotoxic Doses of Acetaminophen Using High-Performance Liquid Chromatography with Electrochemical Detection
      Kenneth L. Muldrew, Laura P. James, Leslie Coop, Sandra S. McCullough, Howard P. Hendrickson, Jack A. Hinson and Philip R. Mayeux
      Drug Metabolism and Disposition April 2002, 30 (4) 446-451; DOI: https://doi.org/10.1124/dmd.30.4.446

  5. Hu, Ming

    1. Absorption and Metabolism of Flavonoids in the Caco-2 Cell Culture Model and a Perused Rat Intestinal Model
      Yan Liu and Ming Hu
      Drug Metabolism and Disposition April 2002, 30 (4) 370-377; DOI: https://doi.org/10.1124/dmd.30.4.370

  6. Hu, Peidi

    1. Delineating the Contribution of Secretory Transporters in the Efflux of Etoposide Using Madin-Darby Canine Kidney (MDCK) Cells Overexpressing P-Glycoprotein (Pgp), Multidrug Resistance-Associated Protein (MRP1), and Canalicular Multispecific Organic Anion Transporter (cMOAT)
      Ailan Guo, William Marinaro, Peidi Hu and Patrick J. Sinko
      Drug Metabolism and Disposition April 2002, 30 (4) 457-463; DOI: https://doi.org/10.1124/dmd.30.4.457

  7. Hulot, Thierry

    1. Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin
      Sebastien Bolze, Norbert Bromet, Croisine Gay-Feutry, Frederic Massiere, Roselyne Boulieu and Thierry Hulot
      Drug Metabolism and Disposition April 2002, 30 (4) 404-413; DOI: https://doi.org/10.1124/dmd.30.4.404

  8. Hummel, Matthew A.

    1. Polymorphic Variants (CYP2C9*3 and CYP2C9*5) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles
      Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Allan E. Rettie, Matthew A. Hummel and Leslie J. Dickmann
      Drug Metabolism and Disposition April 2002, 30 (4) 385-390; DOI: https://doi.org/10.1124/dmd.30.4.385

  9. Hutzler, J. Matthew

    1. Atypical Kinetic Profiles in Drug Metabolism Reactions
      J. Matthew Hutzler and Timothy S. Tracy
      Drug Metabolism and Disposition April 2002, 30 (4) 355-362; DOI: https://doi.org/10.1124/dmd.30.4.355
    2. Polymorphic Variants (CYP2C9*3 and CYP2C9*5) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles
      Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Allan E. Rettie, Matthew A. Hummel and Leslie J. Dickmann
      Drug Metabolism and Disposition April 2002, 30 (4) 385-390; DOI: https://doi.org/10.1124/dmd.30.4.385

I

  1. Iannucci, Robert

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  2. Ishida, Seiichi

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

  3. Itoda, Masaya

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

J

  1. James, Laura P.

    1. Determination of Acetaminophen-Protein Adducts in Mouse Liver and Serum and Human Serum after Hepatotoxic Doses of Acetaminophen Using High-Performance Liquid Chromatography with Electrochemical Detection
      Kenneth L. Muldrew, Laura P. James, Leslie Coop, Sandra S. McCullough, Howard P. Hendrickson, Jack A. Hinson and Philip R. Mayeux
      Drug Metabolism and Disposition April 2002, 30 (4) 446-451; DOI: https://doi.org/10.1124/dmd.30.4.446

  2. Jinno, Hideto

    1. Interaction of Irinotecan (CPT-11) and Its Active Metabolite 7-Ethyl-10-Hydroxycamptothecin (SN-38) with Human Cytochrome P450 Enzymes
      Nobumitsu Hanioka, Shogo Ozawa, Hideto Jinno, Toshiko Tanaka-Kagawa, Tetsuji Nishimura, Masanori Ando and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 391-396; DOI: https://doi.org/10.1124/dmd.30.4.391

  3. John, Brian

    1. Distribution of Brimonidine into Anterior and Posterior Tissues of Monkey, Rabbit, and Rat Eyes
      Andrew A. Acheampong, Martha Shackleton, Brian John, James Burke, Larry Wheeler and Diane Tang-Liu
      Drug Metabolism and Disposition April 2002, 30 (4) 421-429; DOI: https://doi.org/10.1124/dmd.30.4.421

K

  1. Kim, Richard B.

    1. The Anthelminthic Agent Albendazole Does Not Interact with P-Glycoprotein
      Gracia Merino, Ana I. Alvarez, Julio G. Prieto and Richard B. Kim
      Drug Metabolism and Disposition April 2002, 30 (4) 365-369; DOI: https://doi.org/10.1124/dmd.30.4.365

  2. Kitamura, Shigeyuki

    1. Reductive Metabolism of an α,β-Ketoalkyne, 4-Phenyl-3-Butyn-2-One, by Rat Liver Preparations
      Shigeyuki Kitamura, Yoichi Kohno, Yuji Okamoto, Mitsuhiro Takeshita and Shigeru Ohta
      Drug Metabolism and Disposition April 2002, 30 (4) 414-420; DOI: https://doi.org/10.1124/dmd.30.4.414

  3. Kohno, Yoichi

    1. Reductive Metabolism of an α,β-Ketoalkyne, 4-Phenyl-3-Butyn-2-One, by Rat Liver Preparations
      Shigeyuki Kitamura, Yoichi Kohno, Yuji Okamoto, Mitsuhiro Takeshita and Shigeru Ohta
      Drug Metabolism and Disposition April 2002, 30 (4) 414-420; DOI: https://doi.org/10.1124/dmd.30.4.414

  4. Kosoglou, Teddy

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

L

  1. Lazarus, Philip

    1. Glucuronidation: An Important Mechanism for Detoxification of Benzo[a]Pyrene Metabolites in Aerodigestive Tract Tissues
      Zhong Zheng, Jia-Long Fang and Philip Lazarus
      Drug Metabolism and Disposition April 2002, 30 (4) 397-403; DOI: https://doi.org/10.1124/dmd.30.4.397

  2. Liu, Yan

    1. Absorption and Metabolism of Flavonoids in the Caco-2 Cell Culture Model and a Perused Rat Intestinal Model
      Yan Liu and Ming Hu
      Drug Metabolism and Disposition April 2002, 30 (4) 370-377; DOI: https://doi.org/10.1124/dmd.30.4.370

M

  1. Marinaro, William

    1. Delineating the Contribution of Secretory Transporters in the Efflux of Etoposide Using Madin-Darby Canine Kidney (MDCK) Cells Overexpressing P-Glycoprotein (Pgp), Multidrug Resistance-Associated Protein (MRP1), and Canalicular Multispecific Organic Anion Transporter (cMOAT)
      Ailan Guo, William Marinaro, Peidi Hu and Patrick J. Sinko
      Drug Metabolism and Disposition April 2002, 30 (4) 457-463; DOI: https://doi.org/10.1124/dmd.30.4.457

  2. Massiere, Frederic

    1. Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin
      Sebastien Bolze, Norbert Bromet, Croisine Gay-Feutry, Frederic Massiere, Roselyne Boulieu and Thierry Hulot
      Drug Metabolism and Disposition April 2002, 30 (4) 404-413; DOI: https://doi.org/10.1124/dmd.30.4.404

  3. Maxwell, Stephen E.

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  4. Mayeux, Philip R.

    1. Determination of Acetaminophen-Protein Adducts in Mouse Liver and Serum and Human Serum after Hepatotoxic Doses of Acetaminophen Using High-Performance Liquid Chromatography with Electrochemical Detection
      Kenneth L. Muldrew, Laura P. James, Leslie Coop, Sandra S. McCullough, Howard P. Hendrickson, Jack A. Hinson and Philip R. Mayeux
      Drug Metabolism and Disposition April 2002, 30 (4) 446-451; DOI: https://doi.org/10.1124/dmd.30.4.446

  5. McCullough, Sandra S.

    1. Determination of Acetaminophen-Protein Adducts in Mouse Liver and Serum and Human Serum after Hepatotoxic Doses of Acetaminophen Using High-Performance Liquid Chromatography with Electrochemical Detection
      Kenneth L. Muldrew, Laura P. James, Leslie Coop, Sandra S. McCullough, Howard P. Hendrickson, Jack A. Hinson and Philip R. Mayeux
      Drug Metabolism and Disposition April 2002, 30 (4) 446-451; DOI: https://doi.org/10.1124/dmd.30.4.446

  6. Merino, Gracia

    1. The Anthelminthic Agent Albendazole Does Not Interact with P-Glycoprotein
      Gracia Merino, Ana I. Alvarez, Julio G. Prieto and Richard B. Kim
      Drug Metabolism and Disposition April 2002, 30 (4) 365-369; DOI: https://doi.org/10.1124/dmd.30.4.365

  7. Monsarrat, Bernard

    1. Regioselective Metabolism of Taxoids by Human CYP3A4 and 2C8: Structure-Activity Relationship
      Thierry Cresteil, Bernard Monsarrat, Joelle Dubois, Michelle Sonnier, Paul Alvinerie and Françoise Gueritte
      Drug Metabolism and Disposition April 2002, 30 (4) 438-445; DOI: https://doi.org/10.1124/dmd.30.4.438

  8. Muldrew, Kenneth L.

    1. Determination of Acetaminophen-Protein Adducts in Mouse Liver and Serum and Human Serum after Hepatotoxic Doses of Acetaminophen Using High-Performance Liquid Chromatography with Electrochemical Detection
      Kenneth L. Muldrew, Laura P. James, Leslie Coop, Sandra S. McCullough, Howard P. Hendrickson, Jack A. Hinson and Philip R. Mayeux
      Drug Metabolism and Disposition April 2002, 30 (4) 446-451; DOI: https://doi.org/10.1124/dmd.30.4.446

  9. Murayama, Norie

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

N

  1. Nagano, Michiyo

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

  2. Nishimura, Tetsuji

    1. Interaction of Irinotecan (CPT-11) and Its Active Metabolite 7-Ethyl-10-Hydroxycamptothecin (SN-38) with Human Cytochrome P450 Enzymes
      Nobumitsu Hanioka, Shogo Ozawa, Hideto Jinno, Toshiko Tanaka-Kagawa, Tetsuji Nishimura, Masanori Ando and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 391-396; DOI: https://doi.org/10.1124/dmd.30.4.391

O

  1. Ohta, Shigeru

    1. Reductive Metabolism of an α,β-Ketoalkyne, 4-Phenyl-3-Butyn-2-One, by Rat Liver Preparations
      Shigeyuki Kitamura, Yoichi Kohno, Yuji Okamoto, Mitsuhiro Takeshita and Shigeru Ohta
      Drug Metabolism and Disposition April 2002, 30 (4) 414-420; DOI: https://doi.org/10.1124/dmd.30.4.414

  2. Okamoto, Yuji

    1. Reductive Metabolism of an α,β-Ketoalkyne, 4-Phenyl-3-Butyn-2-One, by Rat Liver Preparations
      Shigeyuki Kitamura, Yoichi Kohno, Yuji Okamoto, Mitsuhiro Takeshita and Shigeru Ohta
      Drug Metabolism and Disposition April 2002, 30 (4) 414-420; DOI: https://doi.org/10.1124/dmd.30.4.414

  3. Ozawa, Shogo

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363
    2. Interaction of Irinotecan (CPT-11) and Its Active Metabolite 7-Ethyl-10-Hydroxycamptothecin (SN-38) with Human Cytochrome P450 Enzymes
      Nobumitsu Hanioka, Shogo Ozawa, Hideto Jinno, Toshiko Tanaka-Kagawa, Tetsuji Nishimura, Masanori Ando and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 391-396; DOI: https://doi.org/10.1124/dmd.30.4.391

P

  1. Patrick, James E.

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  2. Piperopoulos, Georgios

    1. The Oxidative Biotransformation of Losoxantrone (CI-941)
      Ulf D. Renner, Georgios Piperopoulos, Rolf Gebhardt, Gerhard Ehninger and Klaus-Peter Zeller
      Drug Metabolism and Disposition April 2002, 30 (4) 464-478; DOI: https://doi.org/10.1124/dmd.30.4.464

  3. Prieto, Julio G.

    1. The Anthelminthic Agent Albendazole Does Not Interact with P-Glycoprotein
      Gracia Merino, Ana I. Alvarez, Julio G. Prieto and Richard B. Kim
      Drug Metabolism and Disposition April 2002, 30 (4) 365-369; DOI: https://doi.org/10.1124/dmd.30.4.365

R

  1. Renner, Ulf D.

    1. The Oxidative Biotransformation of Losoxantrone (CI-941)
      Ulf D. Renner, Georgios Piperopoulos, Rolf Gebhardt, Gerhard Ehninger and Klaus-Peter Zeller
      Drug Metabolism and Disposition April 2002, 30 (4) 464-478; DOI: https://doi.org/10.1124/dmd.30.4.464

  2. Rettie, Allan E.

    1. Polymorphic Variants (CYP2C9*3 and CYP2C9*5) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles
      Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Allan E. Rettie, Matthew A. Hummel and Leslie J. Dickmann
      Drug Metabolism and Disposition April 2002, 30 (4) 385-390; DOI: https://doi.org/10.1124/dmd.30.4.385

  3. Riley, Robert J.

    1. CYP3A4 Active Site Volume Modification by Mutagenesis of Leucine 211
      Stephen M. Fowler, John M. Taylor, Thomas Friedberg, C. Roland Wolf and Robert J. Riley
      Drug Metabolism and Disposition April 2002, 30 (4) 452-456; DOI: https://doi.org/10.1124/dmd.30.4.452

S

  1. Saeki, Mayumi

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

  2. Sai, Kimie

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

  3. Saito, Yoshiro

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

  4. Sawada, Jun-ichi

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363
    2. Interaction of Irinotecan (CPT-11) and Its Active Metabolite 7-Ethyl-10-Hydroxycamptothecin (SN-38) with Human Cytochrome P450 Enzymes
      Nobumitsu Hanioka, Shogo Ozawa, Hideto Jinno, Toshiko Tanaka-Kagawa, Tetsuji Nishimura, Masanori Ando and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 391-396; DOI: https://doi.org/10.1124/dmd.30.4.391

  5. Shackleton, Martha

    1. Distribution of Brimonidine into Anterior and Posterior Tissues of Monkey, Rabbit, and Rat Eyes
      Andrew A. Acheampong, Martha Shackleton, Brian John, James Burke, Larry Wheeler and Diane Tang-Liu
      Drug Metabolism and Disposition April 2002, 30 (4) 421-429; DOI: https://doi.org/10.1124/dmd.30.4.421

  6. Sinko, Patrick J.

    1. Delineating the Contribution of Secretory Transporters in the Efflux of Etoposide Using Madin-Darby Canine Kidney (MDCK) Cells Overexpressing P-Glycoprotein (Pgp), Multidrug Resistance-Associated Protein (MRP1), and Canalicular Multispecific Organic Anion Transporter (cMOAT)
      Ailan Guo, William Marinaro, Peidi Hu and Patrick J. Sinko
      Drug Metabolism and Disposition April 2002, 30 (4) 457-463; DOI: https://doi.org/10.1124/dmd.30.4.457

  7. Sonnier, Michelle

    1. Regioselective Metabolism of Taxoids by Human CYP3A4 and 2C8: Structure-Activity Relationship
      Thierry Cresteil, Bernard Monsarrat, Joelle Dubois, Michelle Sonnier, Paul Alvinerie and Françoise Gueritte
      Drug Metabolism and Disposition April 2002, 30 (4) 438-445; DOI: https://doi.org/10.1124/dmd.30.4.438

  8. Soyama, Akiko

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

  9. Statkevich, Paul

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  10. Stauber, Kathe L.

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430

  11. Sugiyama, Yuichi

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

  12. Suzuki, Hiroshi

    1. Polymorphisms in the ABCC2 (cMOAT/MRP2) Gene Found in 72 Established Cell Lines Derived from Japanese Individuals: An Association between Single Nucleotide Polymorphisms in the 5′-Untranslated Region and Exon 28
      Masaya Itoda, Yoshiro Saito, Akiko Soyama, Mayumi Saeki, Norie Murayama, Seiichi Ishida, Kimie Sai, Michiyo Nagano, Hiroshi Suzuki, Yuichi Sugiyama, Shogo Ozawa and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 363-364; DOI: https://doi.org/10.1124/dmd.30.4.363

T

  1. Takeshita, Mitsuhiro

    1. Reductive Metabolism of an α,β-Ketoalkyne, 4-Phenyl-3-Butyn-2-One, by Rat Liver Preparations
      Shigeyuki Kitamura, Yoichi Kohno, Yuji Okamoto, Mitsuhiro Takeshita and Shigeru Ohta
      Drug Metabolism and Disposition April 2002, 30 (4) 414-420; DOI: https://doi.org/10.1124/dmd.30.4.414

  2. Tanaka-Kagawa, Toshiko

    1. Interaction of Irinotecan (CPT-11) and Its Active Metabolite 7-Ethyl-10-Hydroxycamptothecin (SN-38) with Human Cytochrome P450 Enzymes
      Nobumitsu Hanioka, Shogo Ozawa, Hideto Jinno, Toshiko Tanaka-Kagawa, Tetsuji Nishimura, Masanori Ando and Jun-ichi Sawada
      Drug Metabolism and Disposition April 2002, 30 (4) 391-396; DOI: https://doi.org/10.1124/dmd.30.4.391

  3. Tang-Liu, Diane

    1. Distribution of Brimonidine into Anterior and Posterior Tissues of Monkey, Rabbit, and Rat Eyes
      Andrew A. Acheampong, Martha Shackleton, Brian John, James Burke, Larry Wheeler and Diane Tang-Liu
      Drug Metabolism and Disposition April 2002, 30 (4) 421-429; DOI: https://doi.org/10.1124/dmd.30.4.421

  4. Taylor, John M.

    1. CYP3A4 Active Site Volume Modification by Mutagenesis of Leucine 211
      Stephen M. Fowler, John M. Taylor, Thomas Friedberg, C. Roland Wolf and Robert J. Riley
      Drug Metabolism and Disposition April 2002, 30 (4) 452-456; DOI: https://doi.org/10.1124/dmd.30.4.452

  5. Tracy, Timothy S.

    1. Atypical Kinetic Profiles in Drug Metabolism Reactions
      J. Matthew Hutzler and Timothy S. Tracy
      Drug Metabolism and Disposition April 2002, 30 (4) 355-362; DOI: https://doi.org/10.1124/dmd.30.4.355
    2. Polymorphic Variants (CYP2C9*3 and CYP2C9*5) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles
      Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Allan E. Rettie, Matthew A. Hummel and Leslie J. Dickmann
      Drug Metabolism and Disposition April 2002, 30 (4) 385-390; DOI: https://doi.org/10.1124/dmd.30.4.385

W

  1. Wheeler, Larry

    1. Distribution of Brimonidine into Anterior and Posterior Tissues of Monkey, Rabbit, and Rat Eyes
      Andrew A. Acheampong, Martha Shackleton, Brian John, James Burke, Larry Wheeler and Diane Tang-Liu
      Drug Metabolism and Disposition April 2002, 30 (4) 421-429; DOI: https://doi.org/10.1124/dmd.30.4.421

  2. Wolf, C. Roland

    1. CYP3A4 Active Site Volume Modification by Mutagenesis of Leucine 211
      Stephen M. Fowler, John M. Taylor, Thomas Friedberg, C. Roland Wolf and Robert J. Riley
      Drug Metabolism and Disposition April 2002, 30 (4) 452-456; DOI: https://doi.org/10.1124/dmd.30.4.452

Z

  1. Zeller, Klaus-Peter

    1. The Oxidative Biotransformation of Losoxantrone (CI-941)
      Ulf D. Renner, Georgios Piperopoulos, Rolf Gebhardt, Gerhard Ehninger and Klaus-Peter Zeller
      Drug Metabolism and Disposition April 2002, 30 (4) 464-478; DOI: https://doi.org/10.1124/dmd.30.4.464

  2. Zheng, Zhong

    1. Glucuronidation: An Important Mechanism for Detoxification of Benzo[a]Pyrene Metabolites in Aerodigestive Tract Tissues
      Zhong Zheng, Jia-Long Fang and Philip Lazarus
      Drug Metabolism and Disposition April 2002, 30 (4) 397-403; DOI: https://doi.org/10.1124/dmd.30.4.397

  3. Zhu, Yali

    1. Disposition of the Selective Cholesterol Absorption Inhibitor Ezetimibe in Healthy Male Subjects
      James E. Patrick, Teddy Kosoglou, Kathe L. Stauber, Kevin B. Alton, Stephen E. Maxwell, Yali Zhu, Paul Statkevich, Robert Iannucci, Swapan Chowdhury, Melton Affrime and Mitchell N. Cayen
      Drug Metabolism and Disposition April 2002, 30 (4) 430-437; DOI: https://doi.org/10.1124/dmd.30.4.430
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