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Research ArticleArticle

Polymorphic Variants (CYP2C9*3 and CYP2C9*5) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles

Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Allan E. Rettie, Matthew A. Hummel and Leslie J. Dickmann
Drug Metabolism and Disposition April 2002, 30 (4) 385-390; DOI: https://doi.org/10.1124/dmd.30.4.385

Article Information

vol. 30 no. 4 385-390
DOI 
https://doi.org/10.1124/dmd.30.4.385
PubMed 
11901091
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 6, 2001
  • Accepted December 14, 2001
  • Published online April 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Timothy S. Tracy1,
  2. J. Matthew Hutzler1,
  3. Robert L. Haining1,2,
  4. Allan E. Rettie2,
  5. Matthew A. Hummel1 and
  6. Leslie J. Dickmann2
  1. 1Deparment of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, West Virginia (T.S.T., J.M.H., M.A.H.); 2Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington (R.L.H., A.E.R., L.J.D.)
  1. Dr. Timothy S. Tracy, Dept. of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Box 9530, Morgantown, WV 26506. E-mail:ttracy{at}hsc.wvu.edu
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Research ArticleArticle

Polymorphic Variants (CYP2C9*3 and CYP2C9*5) and the F114L Active Site Mutation of CYP2C9: Effect on Atypical Kinetic Metabolism Profiles

Timothy S. Tracy, J. Matthew Hutzler, Robert L. Haining, Allan E. Rettie, Matthew A. Hummel and Leslie J. Dickmann
Drug Metabolism and Disposition April 1, 2002, 30 (4) 385-390; DOI: https://doi.org/10.1124/dmd.30.4.385
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