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Research ArticleArticle

Regioselective Metabolism of Taxoids by Human CYP3A4 and 2C8: Structure-Activity Relationship

Thierry Cresteil, Bernard Monsarrat, Joelle Dubois, Michelle Sonnier, Paul Alvinerie and Françoise Gueritte
Drug Metabolism and Disposition April 2002, 30 (4) 438-445; DOI: https://doi.org/10.1124/dmd.30.4.438

Article Information

vol. 30 no. 4 438-445
DOI 
https://doi.org/10.1124/dmd.30.4.438
PubMed 
11901098
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 9, 2001
  • Accepted January 3, 2002
  • Published online April 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Thierry Cresteil1,
  2. Bernard Monsarrat2,
  3. Joelle Dubois3,
  4. Michelle Sonnier1,
  5. Paul Alvinerie2 and
  6. Françoise Gueritte3
  1. 1Centre National de la Recherche Scientifique Unité Mixte Recherche 8532, Villejuif, France (T.C., M.S.); 2Institut de Pharmacologie et de Biologie Structurale, Centre National de la Recherche Scientifique Unité Mixte Recherche 5089, Toulouse, France (B.M., P.A.); 3Institut de Chimie des Substances Naturelles, Centre National de la Recherche Scientifique Unité Propre de Recherche 2301, Gif sur Yvette, France (J.D., F.G.)
  1. Dr. Thierry Cresteil, CNRS-ICSN, Avenue de la Terrasse, 91198 Gif sur Yvette Cedex, France. E-mail: cresteil{at}icsn.cnrs-gif.fr
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Research ArticleArticle

Regioselective Metabolism of Taxoids by Human CYP3A4 and 2C8: Structure-Activity Relationship

Thierry Cresteil, Bernard Monsarrat, Joelle Dubois, Michelle Sonnier, Paul Alvinerie and Françoise Gueritte
Drug Metabolism and Disposition April 1, 2002, 30 (4) 438-445; DOI: https://doi.org/10.1124/dmd.30.4.438
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