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Research ArticleArticle

Triethylenethiophosphoramide Is a Specific Inhibitor of Cytochrome P450 2B6: Implications for Cyclophosphamide Metabolism

James M. Rae, Nadia V. Soukhova, David A. Flockhart and Zeruesenay Desta
Drug Metabolism and Disposition May 2002, 30 (5) 525-530; DOI: https://doi.org/10.1124/dmd.30.5.525

Article Information

vol. 30 no. 5 525-530
DOI 
https://doi.org/10.1124/dmd.30.5.525
PubMed 
11950782
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 29, 2001
  • Accepted January 25, 2002
  • Published online May 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. James M. Rae1,
  2. Nadia V. Soukhova,
  3. David A. Flockhart2 and
  4. Zeruesenay Desta2
  1. Division of Clinical Pharmacology, Departments of Medicine and Pharmacology, Georgetown University Medical Center, Washington, DC
  1. James Michael Rae, University of Michigan Medical Center, Department of Internal Medicine, Med Sci 1, Room 5312, 1150 West Medical Center Drive, Ann Arbor, MI 48109-0612. E-mail address: jimmyrae{at}umich.edu
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Research ArticleArticle

Triethylenethiophosphoramide Is a Specific Inhibitor of Cytochrome P450 2B6: Implications for Cyclophosphamide Metabolism

James M. Rae, Nadia V. Soukhova, David A. Flockhart and Zeruesenay Desta
Drug Metabolism and Disposition May 1, 2002, 30 (5) 525-530; DOI: https://doi.org/10.1124/dmd.30.5.525
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