Table of Contents

Articles

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  Immunohistochemical Localization and Activity of Glutathione Transferase Zeta (GSTZ1–1) in Rat Tissues

  Hoffman B. M. Lantum, Raymond B. Baggs, Daria M. Krenitsky, Philip G. Board and M. W. Anders

  Drug Metabolism and Disposition June 2002, 30 (6) 616-625; DOI: https://doi.org/10.1124/dmd.30.6.616
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  Intestinal Secretion Is a Major Route for Parent Ivermectin Elimination in the Rat

  Céline M. Laffont, Pierre-Louis Toutain, Michel Alvinerie and Alain Bousquet-Mélou

  Drug Metabolism and Disposition June 2002, 30 (6) 626-630; DOI: https://doi.org/10.1124/dmd.30.6.626
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  Trimethoprim and Sulfamethoxazole are Selective Inhibitors of CYP2C8 and CYP2C9, Respectively

  Xia Wen, Jun-Sheng Wang, Janne T. Backman, Jouko Laitila and Pertti J. Neuvonen

  Drug Metabolism and Disposition June 2002, 30 (6) 631-635; DOI: https://doi.org/10.1124/dmd.30.6.631
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  Imipramine N-Glucuronidation in Human Liver Microsomes: Biphasic Kinetics and Characterization of UDP-Glucuronosyltransferase Isoforms

  Miki Nakajima, Eriko Tanaka, Tomo Kobayashi, Noriko Ohashi, Toshiyuki Kume and Tsuyoshi Yokoi

  Drug Metabolism and Disposition June 2002, 30 (6) 636-642; DOI: https://doi.org/10.1124/dmd.30.6.636
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  Involvement of Liver Carboxylesterases in the In Vitro Metabolism of Lidocaine

  Stefan E. H. Alexson, Margareta Diczfalusy, Magnus Halldin and Stellan Swedmark

  Drug Metabolism and Disposition June 2002, 30 (6) 643-647; DOI: https://doi.org/10.1124/dmd.30.6.643
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  Effect of Albumin on Phenytoin and Tolbutamide Metabolism in Human Liver Microsomes: An Impact More Than Protein Binding

  Cuyue Tang, Yuh Lin, A. David Rodrigues and Jiunn H. Lin

  Drug Metabolism and Disposition June 2002, 30 (6) 648-654; DOI: https://doi.org/10.1124/dmd.30.6.648
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  In Vitro Biotransformation of Sildenafil (Viagra) in the Male Rat: The Role of CYP2C11

  Jill S. Warrington, Lisa L. von Moltke, Richard I. Shader and David J. Greenblatt

  Drug Metabolism and Disposition June 2002, 30 (6) 655-657; DOI: https://doi.org/10.1124/dmd.30.6.655
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  Comparison of Bioavailability and Metabolism with Two Commercial Formulations of Cyclosporine A in Rats

  Jens Koehler, Thomas Kuehnel, Frieder Kees, Klaus Hoecherl and Horst F. Grobecker

  Drug Metabolism and Disposition June 2002, 30 (6) 658-662; DOI: https://doi.org/10.1124/dmd.30.6.658
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  Metabolism of 18-Methoxycoronaridine, an Ibogaine Analog, to 18-Hydroxycoronaridine by Genetically Variable CYP2C19

  Wenjiang Zhang, Yamini Ramamoorthy, Rachel F. Tyndale, Stanley D. Glick, Isabelle M. Maisonneuve, Martin E. Kuehne and Edward M. Sellers

  Drug Metabolism and Disposition June 2002, 30 (6) 663-669; DOI: https://doi.org/10.1124/dmd.30.6.663
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  Ocular Disposition of Ganciclovir and Its Monoester Prodrugs following Intravitreal Administration Using Microdialysis

  Sreeraj Macha and Ashim K. Mitra

  Drug Metabolism and Disposition June 2002, 30 (6) 670-675; DOI: https://doi.org/10.1124/dmd.30.6.670
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  Pharmacokinetics of Sodium Nitrite-Induced Methemoglobinemia in the Rat

  Michael C. Kohn, Ronald L. Melnick, Frank Ye and Christopher J. Portier

  Drug Metabolism and Disposition June 2002, 30 (6) 676-683; DOI: https://doi.org/10.1124/dmd.30.6.676
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  The Disposition and Metabolism of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Human Subjects

  Rita A. Halpin, Arturo G. Porras, Leslie A. Geer, Margaret R. Davis, Donghui Cui, George A. Doss, Eric Woolf, Donald Musson, Catherine Matthews, Ralph Mazenko, Jules I. Schwartz, Kenneth C. Lasseter, Kamlesh P. Vyas and Thomas A. Baillie

  Drug Metabolism and Disposition June 2002, 30 (6) 684-693; DOI: https://doi.org/10.1124/dmd.30.6.684
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  Characterization of Raloxifene Glucuronidation in Vitro: Contribution of Intestinal Metabolism to Presystemic Clearance

  Daniel C. Kemp, Peter W. Fan and Jeffrey C. Stevens

  Drug Metabolism and Disposition June 2002, 30 (6) 694-700; DOI: https://doi.org/10.1124/dmd.30.6.694
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  Inhibition Kinetics of Monoclonal Antibodies against Cytochromes P450

  Qin Mei, Cuyue Tang, Yuh Lin, Thomas H. Rushmore and Magang Shou

  Drug Metabolism and Disposition June 2002, 30 (6) 701-708; DOI: https://doi.org/10.1124/dmd.30.6.701
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  The Licorice Root Derived Isoflavan Glabridin Inhibits the Activities of Human Cytochrome P450S 3A4, 2B6, and 2C9

  Ute M. Kent, Michael Aviram, Mira Rosenblat and Paul F. Hollenberg

  Drug Metabolism and Disposition June 2002, 30 (6) 709-715; DOI: https://doi.org/10.1124/dmd.30.6.709
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  Characterization of Butyrylcholinesterase Antagonism of Cocaine-Induced Hyperactivity

  Lee Koetzner and James H. Woods

  Drug Metabolism and Disposition June 2002, 30 (6) 716-723; DOI: https://doi.org/10.1124/dmd.30.6.716
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  Characterization of Equine Butyrylcholinesterase Disposition in the Mouse

  Lee Koetzner and James H. Woods

  Drug Metabolism and Disposition June 2002, 30 (6) 724-730; DOI: https://doi.org/10.1124/dmd.30.6.724
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  Determination of Drug Interactions Occurring with the Metabolic Pathways of Irinotecan

  Virginie Charasson, Marie-Christine Haaz and Jacques Robert

  Drug Metabolism and Disposition June 2002, 30 (6) 731-733; DOI: https://doi.org/10.1124/dmd.30.6.731
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  Quantitative Structure Activity Relationships for the Glucuronidation of Simple Phenols by Expressed Human UGT1A6 and UGT1A9

  Brian T. Ethell, Sean Ekins, Jibo Wang and Brian Burchell

  Drug Metabolism and Disposition June 2002, 30 (6) 734-738; DOI: https://doi.org/10.1124/dmd.30.6.734
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  Increase in Urea in Conjunction with l-Arginine Metabolism in the Liver Leads to Induction of Cytochrome P450 2E1 (CYP2E1): The Role of Urea in CYP2E1 Induction by Acute Renal Failure

  Hye Chin Chung, So Hee Kim, Myung Gull Lee and Sang Geon Kim

  Drug Metabolism and Disposition June 2002, 30 (6) 739-746; DOI: https://doi.org/10.1124/dmd.30.6.739
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  In Vitro Metabolism of Tresperimus by Human Vascular Semicarbazide-Sensitive Amine Oxidase

  Philippe Claud, Yves Artur and Romuald Laine

  Drug Metabolism and Disposition June 2002, 30 (6) 747-755; DOI: https://doi.org/10.1124/dmd.30.6.747