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Drug Metabolism & Disposition

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Table of Contents

June 01, 2002; Volume 30,Issue 6

Short Communication

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    Hepatocyte Nuclear Factor-1α Is a Causal Factor Responsible for Interindividual Differences in the Expression of UDP-Glucuronosyltransferase 2B7 mRNA in Human Livers
    Kenji Toide, Yoshiki Takahashi, Hiroshi Yamazaki, Yoshiaki Terauchi, Toshihiko Fujii, Andrew Parkinson and Tetsuya Kamataki
    Drug Metabolism and Disposition June 2002, 30 (6) 613-615; DOI: https://doi.org/10.1124/dmd.30.6.613

Articles

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    Immunohistochemical Localization and Activity of Glutathione Transferase Zeta (GSTZ1–1) in Rat Tissues
    Hoffman B. M. Lantum, Raymond B. Baggs, Daria M. Krenitsky, Philip G. Board and M. W. Anders
    Drug Metabolism and Disposition June 2002, 30 (6) 616-625; DOI: https://doi.org/10.1124/dmd.30.6.616
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    Intestinal Secretion Is a Major Route for Parent Ivermectin Elimination in the Rat
    Céline M. Laffont, Pierre-Louis Toutain, Michel Alvinerie and Alain Bousquet-Mélou
    Drug Metabolism and Disposition June 2002, 30 (6) 626-630; DOI: https://doi.org/10.1124/dmd.30.6.626
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    Trimethoprim and Sulfamethoxazole are Selective Inhibitors of CYP2C8 and CYP2C9, Respectively
    Xia Wen, Jun-Sheng Wang, Janne T. Backman, Jouko Laitila and Pertti J. Neuvonen
    Drug Metabolism and Disposition June 2002, 30 (6) 631-635; DOI: https://doi.org/10.1124/dmd.30.6.631
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    Imipramine N-Glucuronidation in Human Liver Microsomes: Biphasic Kinetics and Characterization of UDP-Glucuronosyltransferase Isoforms
    Miki Nakajima, Eriko Tanaka, Tomo Kobayashi, Noriko Ohashi, Toshiyuki Kume and Tsuyoshi Yokoi
    Drug Metabolism and Disposition June 2002, 30 (6) 636-642; DOI: https://doi.org/10.1124/dmd.30.6.636
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    Involvement of Liver Carboxylesterases in the In Vitro Metabolism of Lidocaine
    Stefan E. H. Alexson, Margareta Diczfalusy, Magnus Halldin and Stellan Swedmark
    Drug Metabolism and Disposition June 2002, 30 (6) 643-647; DOI: https://doi.org/10.1124/dmd.30.6.643
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    Effect of Albumin on Phenytoin and Tolbutamide Metabolism in Human Liver Microsomes: An Impact More Than Protein Binding
    Cuyue Tang, Yuh Lin, A. David Rodrigues and Jiunn H. Lin
    Drug Metabolism and Disposition June 2002, 30 (6) 648-654; DOI: https://doi.org/10.1124/dmd.30.6.648
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    In Vitro Biotransformation of Sildenafil (Viagra) in the Male Rat: The Role of CYP2C11
    Jill S. Warrington, Lisa L. von Moltke, Richard I. Shader and David J. Greenblatt
    Drug Metabolism and Disposition June 2002, 30 (6) 655-657; DOI: https://doi.org/10.1124/dmd.30.6.655
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    Comparison of Bioavailability and Metabolism with Two Commercial Formulations of Cyclosporine A in Rats
    Jens Koehler, Thomas Kuehnel, Frieder Kees, Klaus Hoecherl and Horst F. Grobecker
    Drug Metabolism and Disposition June 2002, 30 (6) 658-662; DOI: https://doi.org/10.1124/dmd.30.6.658
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    Metabolism of 18-Methoxycoronaridine, an Ibogaine Analog, to 18-Hydroxycoronaridine by Genetically Variable CYP2C19
    Wenjiang Zhang, Yamini Ramamoorthy, Rachel F. Tyndale, Stanley D. Glick, Isabelle M. Maisonneuve, Martin E. Kuehne and Edward M. Sellers
    Drug Metabolism and Disposition June 2002, 30 (6) 663-669; DOI: https://doi.org/10.1124/dmd.30.6.663
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    Ocular Disposition of Ganciclovir and Its Monoester Prodrugs following Intravitreal Administration Using Microdialysis
    Sreeraj Macha and Ashim K. Mitra
    Drug Metabolism and Disposition June 2002, 30 (6) 670-675; DOI: https://doi.org/10.1124/dmd.30.6.670
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    Pharmacokinetics of Sodium Nitrite-Induced Methemoglobinemia in the Rat
    Michael C. Kohn, Ronald L. Melnick, Frank Ye and Christopher J. Portier
    Drug Metabolism and Disposition June 2002, 30 (6) 676-683; DOI: https://doi.org/10.1124/dmd.30.6.676
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    The Disposition and Metabolism of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Human Subjects
    Rita A. Halpin, Arturo G. Porras, Leslie A. Geer, Margaret R. Davis, Donghui Cui, George A. Doss, Eric Woolf, Donald Musson, Catherine Matthews, Ralph Mazenko, Jules I. Schwartz, Kenneth C. Lasseter, Kamlesh P. Vyas and Thomas A. Baillie
    Drug Metabolism and Disposition June 2002, 30 (6) 684-693; DOI: https://doi.org/10.1124/dmd.30.6.684
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    Characterization of Raloxifene Glucuronidation in Vitro: Contribution of Intestinal Metabolism to Presystemic Clearance
    Daniel C. Kemp, Peter W. Fan and Jeffrey C. Stevens
    Drug Metabolism and Disposition June 2002, 30 (6) 694-700; DOI: https://doi.org/10.1124/dmd.30.6.694
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    Inhibition Kinetics of Monoclonal Antibodies against Cytochromes P450
    Qin Mei, Cuyue Tang, Yuh Lin, Thomas H. Rushmore and Magang Shou
    Drug Metabolism and Disposition June 2002, 30 (6) 701-708; DOI: https://doi.org/10.1124/dmd.30.6.701
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    The Licorice Root Derived Isoflavan Glabridin Inhibits the Activities of Human Cytochrome P450S 3A4, 2B6, and 2C9
    Ute M. Kent, Michael Aviram, Mira Rosenblat and Paul F. Hollenberg
    Drug Metabolism and Disposition June 2002, 30 (6) 709-715; DOI: https://doi.org/10.1124/dmd.30.6.709
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    Characterization of Butyrylcholinesterase Antagonism of Cocaine-Induced Hyperactivity
    Lee Koetzner and James H. Woods
    Drug Metabolism and Disposition June 2002, 30 (6) 716-723; DOI: https://doi.org/10.1124/dmd.30.6.716
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    Characterization of Equine Butyrylcholinesterase Disposition in the Mouse
    Lee Koetzner and James H. Woods
    Drug Metabolism and Disposition June 2002, 30 (6) 724-730; DOI: https://doi.org/10.1124/dmd.30.6.724
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    Determination of Drug Interactions Occurring with the Metabolic Pathways of Irinotecan
    Virginie Charasson, Marie-Christine Haaz and Jacques Robert
    Drug Metabolism and Disposition June 2002, 30 (6) 731-733; DOI: https://doi.org/10.1124/dmd.30.6.731
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    Quantitative Structure Activity Relationships for the Glucuronidation of Simple Phenols by Expressed Human UGT1A6 and UGT1A9
    Brian T. Ethell, Sean Ekins, Jibo Wang and Brian Burchell
    Drug Metabolism and Disposition June 2002, 30 (6) 734-738; DOI: https://doi.org/10.1124/dmd.30.6.734
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    Increase in Urea in Conjunction with l-Arginine Metabolism in the Liver Leads to Induction of Cytochrome P450 2E1 (CYP2E1): The Role of Urea in CYP2E1 Induction by Acute Renal Failure
    Hye Chin Chung, So Hee Kim, Myung Gull Lee and Sang Geon Kim
    Drug Metabolism and Disposition June 2002, 30 (6) 739-746; DOI: https://doi.org/10.1124/dmd.30.6.739
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    In Vitro Metabolism of Tresperimus by Human Vascular Semicarbazide-Sensitive Amine Oxidase
    Philippe Claud, Yves Artur and Romuald Laine
    Drug Metabolism and Disposition June 2002, 30 (6) 747-755; DOI: https://doi.org/10.1124/dmd.30.6.747
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Drug Metabolism and Disposition: 30 (6)
Drug Metabolism and Disposition
Vol. 30, Issue 6
1 Jun 2002
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