Imipramine N-Glucuronidation in Human Liver Microsomes: Biphasic Kinetics and Characterization of UDP-Glucuronosyltransferase Isoforms

Miki Nakajima, Ph.D., Division of Drug Metabolism, Faculty of Pharmaceutical Sciences, Kanazawa University, Takara-machi 13-1, Kanazawa 920-0934, Japan. E-mail: nmiki{at}kenroku.kanazawa-u.ac.jp

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May 2002	53	25	112
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Jul 2002	14	37	58
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Apr 2011	7	19	9
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Jul 2014	12	10	13
Aug 2014	9	5	3
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Oct 2014	14	5	6
Nov 2014	11	8	8
Dec 2014	13	4	8
Jan 2015	9	5	2
Feb 2015	16	18	14
Mar 2015	22	6	11
Apr 2015	11	6	3
May 2015	19	10	4
Jun 2015	15	12	9
Jul 2015	15	4	7
Aug 2015	13	12	10
Sep 2015	14	0	3
Oct 2015	11	5	4
Nov 2015	20	29	15
Dec 2015	8	7	7
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Feb 2016	6	14	6
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Apr 2016	6	5	6
May 2016	9	9	15
Jun 2016	10	3	0
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Feb 2017	0	14	5
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Apr 2017	0	11	8
May 2017	0	20	25
Jun 2017	2	13	5
Jul 2017	4	10	9
Aug 2017	1	23	10
Sep 2017	1	17	8
Oct 2017	0	29	5
Nov 2017	0	49	18
Dec 2017	5	24	5
Jan 2018	6	24	8
Feb 2018	1	13	0
Mar 2018	1	19	4
Apr 2018	0	17	6
May 2018	0	17	5
Jun 2018	1	21	8
Jul 2018	1	19	5
Aug 2018	2	14	7
Sep 2018	0	45	2
Oct 2018	0	25	8
Nov 2018	2	33	8
Dec 2018	19	6	3
Jan 2019	16	4	2
Feb 2019	12	2	3
Mar 2019	15	6	0
Apr 2019	17	1	0
May 2019	21	0	0
Jun 2019	7	1	3
Jul 2019	14	0	0
Aug 2019	12	4	0
Sep 2019	25	3	2
Oct 2019	23	6	1
Nov 2019	15	0	1
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Feb 2020	8	3	0
Mar 2020	23	9	3
Apr 2020	13	8	2
May 2020	9	0	0
Jun 2020	12	0	1
Jul 2020	10	2	1
Aug 2020	8	0	4
Sep 2020	10	6	3
Oct 2020	11	3	1
Nov 2020	9	0	2
Dec 2020	8	5	0
Jan 2021	10	26	1
Feb 2021	17	28	3
Mar 2021	12	6	1
Apr 2021	9	2	0
May 2021	8	8	0
Jun 2021	15	20	2
Jul 2021	10	3	0